SUPERFAMILY 1.75 HMM library and genome assignments server

SUPERFAMILY 2 can be accessed from supfam.org. Please contact us if you experience any problems.

Mammalian Phenotype (MP): decreased cell death

(show info)

Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Root: MP Hierarchy (mammalian/mouse phenotype from MGI_4.41)

Shortest distance to current term (+ for parents, - for children) MP term [MP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + + 4:   mammalian phenotype [MP:0000001] <29>
+ + + 3:   cellular phenotype [MP:0005384] <6>(95|116) (103|56|31)
+ + 2:   abnormal cell physiology [MP:0005621] <24>(77|96) (84|46|25)
+ 1:   abnormal cell death [MP:0000313] <5>(29|41) (33|15|5)
0:   decreased cell death [MP:0012555] <1>(4|5) (5|3|1)
- 1:   decreased apoptosis [MP:0006043] <18>(3|5) (5|3|1)


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Superfamily

(show details)
SCOP termFDR (all)Annotation (direct or inherited)
p53 tetramerization domain0Direct
Caspase-like0.00007097Direct
DEATH domain0.0001819Direct
Bcl-2 inhibitors of programmed cell death0.0008153Direct


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Family

(show details)
SCOP termFDR (all)Annotation (direct or inherited)
p53 DNA-binding domain-like0Direct
p53 tetramerization domain0Direct
Caspase catalytic domain0.00004813Direct
Bcl-2 inhibitors of programmed cell death0.0005547Direct
Toll/Interleukin receptor TIR domain0.02441Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
Plot tree as:   Download Newick format tree:
(show help)

Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

(show details)
Supra-domain (Single) FDR (all) Annotation (direct or inherited)
p53 tetramerization domain0Direct
Caspase-like0.00003392Direct
DEATH domain0.00009154Direct
Bcl-2 inhibitors of programmed cell death0.0004412Direct
Leucine zipper domain0.07171Inherited

(show details)
Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
49417,47719
  • 49417 - p53-like transcription factors
  • 47719 - p53 tetramerization domain
  • 0Direct
    47986,52129
  • 47986 - DEATH domain
  • 52129 - Caspase-like
  • 0.006582Inherited
    57586,57586
  • 57586 - TNF receptor-like
  • 57586 - TNF receptor-like
  • 0.04349Inherited

    (show details)
    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    47459,55785,55785
  • 47459 - HLH, helix-loop-helix DNA-binding domain
  • 55785 - PYP-like sensor domain (PAS domain)
  • 55785 - PYP-like sensor domain (PAS domain)
  • 0.0005441Direct


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
    Plot tree as:   Download Newick format tree:
    (show help)