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Mammalian Phenotype (MP): abnormal alpha-beta T cell morphology

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Root: MP Hierarchy (mammalian/mouse phenotype from MGI_4.41)

Shortest distance to current term (+ for parents, - for children) MP term [MP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + + + + + + 8:   mammalian phenotype [MP:0000001] <29>
+ + + + + + + 7:   immune system phenotype [MP:0005387] <2>(76|114) (86|66|35)
+ + + + + + + 7:   hematopoietic system phenotype [MP:0005397] <2>(72|102) (78|63|30)
+ + + + + + 6:   abnormal hematopoietic system morphology/development [MP:0002396] <5>(57|86) (66|47|21)
+ + + + + + 6:   abnormal immune system morphology [MP:0000685] <3>(50|76) (60|35|18)
+ + + + + 5:   abnormal immune system cell morphology [MP:0000716] <5>(37|63) (48|29|16)
+ + + + + 5:   abnormal hematopoietic cell morphology [MP:0013656] <9>(48|77) (60|43|18)
+ + + + 4:   abnormal leukocyte morphology [MP:0008246] <4>(36|62) (47|29|15)
+ + + 3:   abnormal mononuclear cell morphology [MP:0008247] <2>(33|57) (41|28|14)
+ + 2:   abnormal lymphocyte morphology [MP:0002619] <5>(27|46) (33|26|14)
+ 1:   abnormal T cell morphology [MP:0008037] <9>(14|25) (18|19|11)
0:   abnormal alpha-beta T cell morphology [MP:0012762] <13>(7|17) (8|14|6)
- 1:   abnormal CD8-positive, alpha beta T cell morphology [MP:0005010] <7>(3|8) (3|6|2)
- 1:   abnormal CD4-positive, alpha beta T cell morphology [MP:0002432] <6>(3|11) (4|10|4)
- 1:   abnormal alpha-beta T cell number [MP:0012763] <5>(3|11) (4|8|2)
- 1:   abnormal CD4-positive, alpha-beta memory T cell morphology [MP:0010834] <2>(0|0) (0|0|0)
- 1:   abnormal CD8-positive, alpha-beta memory T cell morphology [MP:0010837] <2>(0|0) (0|0|0)
- 1:   abnormal alpha-beta intraepithelial T cell morphology [MP:0008399] <2>(0|0) (0|0|0)
- 1:   abnormal double-positive T cell morphology [MP:0002408] <2>(1|2) (1|3|1)
- 1:   abnormal CD4-positive, CD25-positive, alpha-beta regulatory T cell morphology [MP:0008397] <1>(0|0) (0|0|0)
- 1:   abnormal NK T cell morphology [MP:0008036] <1>(0|0) (0|0|0)
- 1:   abnormal CD4-positive, alpha-beta intraepithelial T cell morphology [MP:0008400](0|0) (0|0|0)
- 1:   abnormal CD8 positive, alpha-beta intraepithelial T cell morphology [MP:0008401](0|0) (0|0|0)
- 1:   abnormal CD8-positive, alpha-beta cytotoxic T cell morphology [MP:0002436](0|0) (0|0|0)
- 1:   abnormal CD8-positive, alpha-beta regulatory T cell morphology [MP:0008398](0|0) (0|0|0)


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Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
E2F-DP heterodimerization region0.001536Inherited
N-terminal nucleophile aminohydrolases (Ntn hydrolases)0.002112Inherited
MHC antigen-recognition domain0.2022Inherited
STAT0.3291Inherited
Transcription factor STAT-4 N-domain0.3291Inherited
SH3-domain0.5158Inherited
Integrin domains0.7951Inherited


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Family

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SCOP termFDR (all)Annotation (direct or inherited)
Proteasome subunits0Direct
E2F dimerization segment0.000377Direct
Phoshoinositide 3-kinase (PI3K) helical domain0.000997Direct
Cell cycle transcription factor e2f-dp0.003801Inherited
MHC antigen-recognition domain0.1628Inherited
NF-kappa-B/REL/DORSAL transcription factors, C-terminal domain0.1955Inherited
Rel/Dorsal transcription factors, DNA-binding domain0.2343Inherited
Phoshoinositide 3-kinase (PI3K), catalytic domain0.2343Inherited
STAT DNA-binding domain0.2816Inherited
STAT0.2816Inherited
Transcription factor STAT-4 N-domain0.2816Inherited
C1 set domains (antibody constant domain-like)0.2858Inherited
V set domains (antibody variable domain-like)0.3088Inherited
Interleukin 17F, IL-17F0.4066Inherited
SH3-domain0.4549Inherited
Integrin domains0.755Inherited
TNF receptor-like0.9908Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
E2F-DP heterodimerization region0.0008616Direct
N-terminal nucleophile aminohydrolases (Ntn hydrolases)0.001204Inherited
MHC antigen-recognition domain0.1653Inherited
STAT0.2845Inherited
Transcription factor STAT-4 N-domain0.2845Inherited
SH3-domain0.4683Inherited
Integrin domains0.76Inherited
TNF receptor-like0.9851Inherited

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Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
47576,48065
  • 47576 - Calponin-homology domain, CH-domain
  • 48065 - DBL homology domain (DH-domain)
  • 0Direct
    50729,56112
  • 50729 - PH domain-like
  • 56112 - Protein kinase-like (PK-like)
  • 0.000005252Direct
    55550,55550
  • 55550 - SH2 domain
  • 55550 - SH2 domain
  • 0.0003226Direct
    55550,50044
  • 55550 - SH2 domain
  • 50044 - SH3-domain
  • 0.0003331Direct
    46785,144074
  • 46785 - "Winged helix" DNA-binding domain
  • 144074 - E2F-DP heterodimerization region
  • 0.0008616Direct
    49562,48371
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 48371 - ARM repeat
  • 0.0008616Direct
    48371,56112
  • 48371 - ARM repeat
  • 56112 - Protein kinase-like (PK-like)
  • 0.003307Inherited
    47986,47986
  • 47986 - DEATH domain
  • 47986 - DEATH domain
  • 0.0048Inherited
    53300,69318
  • 53300 - vWA-like
  • 69318 - Integrin alpha N-terminal domain
  • 0.01434Inherited
    54452,48726
  • 54452 - MHC antigen-recognition domain
  • 48726 - Immunoglobulin
  • 0.1653Inherited
    49417,81296
  • 49417 - p53-like transcription factors
  • 81296 - E set domains
  • 0.2371Inherited
    49417,55550
  • 49417 - p53-like transcription factors
  • 55550 - SH2 domain
  • 0.2845Inherited
    48092,47655
  • 48092 - Transcription factor STAT-4 N-domain
  • 47655 - STAT
  • 0.2845Inherited
    47655,49417
  • 47655 - STAT
  • 49417 - p53-like transcription factors
  • 0.2845Inherited

    (show details)
    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    50044,55550,50044
  • 50044 - SH3-domain
  • 55550 - SH2 domain
  • 50044 - SH3-domain
  • 0Direct
    47576,48065,50729
  • 47576 - Calponin-homology domain, CH-domain
  • 48065 - DBL homology domain (DH-domain)
  • 50729 - PH domain-like
  • 0Direct
    49562,48371,56112
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 48371 - ARM repeat
  • 56112 - Protein kinase-like (PK-like)
  • 0.0008616Direct
    53300,69318,69179
  • 53300 - vWA-like
  • 69318 - Integrin alpha N-terminal domain
  • 69179 - Integrin domains
  • 0.01434Inherited
    47655,49417,55550
  • 47655 - STAT
  • 49417 - p53-like transcription factors
  • 55550 - SH2 domain
  • 0.2845Inherited
    48092,47655,49417
  • 48092 - Transcription factor STAT-4 N-domain
  • 47655 - STAT
  • 49417 - p53-like transcription factors
  • 0.2845Inherited


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
    Plot tree as:   Download Newick format tree:
    (show help)