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Mammalian Phenotype (MP): embryonic lethality prior to organogenesis

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Root: MP Hierarchy (mammalian/mouse phenotype from MGI_4.41)

Shortest distance to current term (+ for parents, - for children) MP term [MP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + + + + + 7:   mammalian phenotype [MP:0000001] <29>
+ + + + + 5:   mortality/aging [MP:0010768] <4>(83|115) (89|67|50)
+ + + + 4:   preweaning lethality [MP:0010770] <4>(48|79) (55|45|38)
+ + + + 4:   abnormal survival [MP:0010769] <10>(60|91) (67|55|39)
+ + + 3:   prenatal lethality [MP:0002080] <5>(27|49) (30|23|16)
+ + 2:   embryonic lethality [MP:0008762] <4>(16|30) (16|11|7)
+ 1:   embryonic lethality prior to tooth bud stage [MP:0013293] <1>(10|14) (10|5|1)
0:   embryonic lethality prior to organogenesis [MP:0013292] <3>(10|14) (10|5|1)
- 1:   embryonic lethality between implantation and placentation [MP:0009850] <4>(3|8) (4|3|0)
- 1:   embryonic lethality at implantation [MP:0008527] <2>(0|0) (0|0|0)
- 1:   embryonic lethality before implantation [MP:0006204] <2>(0|1) (0|0|0)


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Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
GroEL-intermediate domain like0Direct
BRCT domain0.000001388Direct
SCOP hierarchy in SUPERFAMILY0.0001219Direct
Nucleic acid-binding proteins0.0003194Direct
dsRNA-binding domain-like0.0003819Direct
Subtilisin-like0.0007057Direct
ADC-like0.0007404Direct
Zinc beta-ribbon0.0007404Direct
GroEL apical domain-like0.002477Inherited
Cullin homology domain0.009944Inherited


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Family

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SCOP termFDR (all)Annotation (direct or inherited)
Phoshoinositide 3-kinase (PI3K), catalytic domain0.00002111Direct
Extended AAA-ATPase domain0.0001696Direct
Subtilases0.0001958Direct
DNA polymerase I0.0002074Direct
Proprotein convertase P-domain0.0002074Direct
Prohormone convertase 1 pro-domain0.0002074Direct
Tandem AAA-ATPase domain0.0002977Direct
SCF ubiquitin ligase complex WHB domain0.001513Inherited
Extracellular domain of cell surface receptors0.003662Inherited
N-acetyl transferase, NAT0.004091Inherited
Cullin homology domain0.006523Inherited
Linker histone H1/H50.01593Inherited
Ubiquitin carboxyl-terminal hydrolase, UCH0.1919Inherited
Armadillo repeat0.716Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
GroEL-intermediate domain like0Direct
BRCT domain0.0000005689Direct
Nucleic acid-binding proteins0.0001653Direct
dsRNA-binding domain-like0.000199Direct
Subtilisin-like0.0003775Direct
ADC-like0.0003975Direct
Zinc beta-ribbon0.0003975Direct
GroEL apical domain-like0.001423Inherited
Cullin homology domain0.006207Inherited
Acyl-CoA N-acyltransferases (Nat)0.01137Inherited

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Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
54849,52029
  • 54849 - GroEL-intermediate domain like
  • 52029 - GroEL apical domain-like
  • 0Direct
    52113,52113
  • 52113 - BRCT domain
  • 52113 - BRCT domain
  • 0.00002301Direct
    52743,49785
  • 52743 - Subtilisin-like
  • 49785 - Galactose-binding domain-like
  • 0.0001929Direct
    52540,52540
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.0002554Direct
    75632,46785
  • 75632 - Cullin homology domain
  • 46785 - "Winged helix" DNA-binding domain
  • 0.001423Inherited

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    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    54897,52743,49785
  • 54897 - Protease propeptides/inhibitors
  • 52743 - Subtilisin-like
  • 49785 - Galactose-binding domain-like
  • 0.0001929Direct


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
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