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Mammalian Phenotype (MP): abnormal endocrine gland physiology

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Root: MP Hierarchy (mammalian/mouse phenotype from MGI_4.41)

Shortest distance to current term (+ for parents, - for children) MP term [MP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + 3:   mammalian phenotype [MP:0000001] <29>
+ + 2:   endocrine/exocrine gland phenotype [MP:0005379] <2>(51|81) (55|36|12)
+ 1:   abnormal gland physiology [MP:0002164] <4>(9|19) (11|11|5)
0:   abnormal endocrine gland physiology [MP:0013561] <6>(4|10) (4|6|2)
- 1:   abnormal endocrine pancreas physiology [MP:0010147] <6>(3|7) (3|5|2)
- 1:   abnormal thymus physiology [MP:0003763] <4>(1|2) (1|1|0)
- 1:   abnormal thyroid physiology [MP:0002876] <4>(0|0) (0|0|0)
- 1:   abnormal adrenal gland physiology [MP:0002909] <2>(0|1) (0|0|0)
- 1:   abnormal neuroendocrine gland physiology [MP:0013570] <2>(0|0) (0|0|0)
- 1:   abnormal parathyroid gland physiology [MP:0003431] <2>(0|0) (0|0|0)


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Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
Caspase-like0.0000003858Direct
Thyroglobulin type-1 domain0.02501Inherited
STAT0.1763Inherited
Transcription factor STAT-4 N-domain0.1763Inherited


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Family

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SCOP termFDR (all)Annotation (direct or inherited)
Caspase catalytic domain0.00000009775Direct
FYVE, a phosphatidylinositol-3-phosphate binding domain0.01623Inherited
Thyroglobulin type-1 domain0.02Inherited
Caspase recruitment domain, CARD0.02407Inherited
Pleckstrin-homology domain (PH domain)0.06568Inherited
STAT DNA-binding domain0.1352Inherited
STAT0.1352Inherited
Transcription factor STAT-4 N-domain0.1352Inherited
Forkhead DNA-binding domain0.2238Inherited
Growth factor receptor domain0.8426Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
Caspase-like0.0000001552Direct
Thyroglobulin type-1 domain0.01672Inherited
STAT0.1418Inherited
Transcription factor STAT-4 N-domain0.1418Inherited

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Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
47986,52129
  • 47986 - DEATH domain
  • 52129 - Caspase-like
  • 0.00001777Direct
    57184,57610
  • 57184 - Growth factor receptor domain
  • 57610 - Thyroglobulin type-1 domain
  • 0.0005779Direct
    49417,55550
  • 49417 - p53-like transcription factors
  • 55550 - SH2 domain
  • 0.1418Inherited
    48092,47655
  • 48092 - Transcription factor STAT-4 N-domain
  • 47655 - STAT
  • 0.1418Inherited
    47655,49417
  • 47655 - STAT
  • 49417 - p53-like transcription factors
  • 0.1418Inherited
    57716,48508
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 48508 - Nuclear receptor ligand-binding domain
  • 0.1827Inherited

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    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    47655,49417,55550
  • 47655 - STAT
  • 49417 - p53-like transcription factors
  • 55550 - SH2 domain
  • 0.1418Inherited
    48092,47655,49417
  • 48092 - Transcription factor STAT-4 N-domain
  • 47655 - STAT
  • 49417 - p53-like transcription factors
  • 0.1418Inherited


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
    Plot tree as:   Download Newick format tree:
    (show help)