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Mammalian Phenotype (MP): abnormal endocrine pancreas secretion

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Root: MP Hierarchy (mammalian/mouse phenotype from MGI_4.41)

Shortest distance to current term (+ for parents, - for children) MP term [MP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + + + 5:   mammalian phenotype [MP:0000001] <29>
+ + + + 4:   endocrine/exocrine gland phenotype [MP:0005379] <2>(51|81) (55|36|12)
+ + + 3:   abnormal gland physiology [MP:0002164] <4>(9|19) (11|11|5)
+ + 2:   abnormal pancreas physiology [MP:0002693] <8>(5|12) (5|7|3)
+ 1:   abnormal pancreas secretion [MP:0002694] <2>(5|10) (5|7|3)
0:   abnormal endocrine pancreas secretion [MP:0014195] <6>(3|8) (3|5|2)
- 1:   abnormal amylin secretion [MP:0014123] <2>(0|0) (0|0|0)
- 1:   abnormal glucagon secretion [MP:0003565] <2>(0|0) (0|0|0)
- 1:   abnormal insulin secretion [MP:0003564] <2>(1|4) (1|1|0)
- 1:   abnormal pancreatic ghrelin secretion [MP:0009196](0|0) (0|0|0)
- 1:   abnormal pancreatic polypeptide secretion [MP:0009197](0|0) (0|0|0)
- 1:   abnormal pancreatic somatostatin secretion [MP:0008953](0|0) (0|0|0)


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Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
STAT0.0001612Direct
Transcription factor STAT-4 N-domain0.0001612Direct
Thyroglobulin type-1 domain0.002772Inherited


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Family

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SCOP termFDR (all)Annotation (direct or inherited)
STAT DNA-binding domain0.00009488Direct
STAT0.00009488Direct
Transcription factor STAT-4 N-domain0.00009488Direct
Forkhead DNA-binding domain0.0001183Direct
Ras-binding domain, RBD0.0009447Direct
FYVE, a phosphatidylinositol-3-phosphate binding domain0.001444Inherited
Thyroglobulin type-1 domain0.001829Inherited
Growth factor receptor domain0.02016Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
STAT0.00008059Direct
Transcription factor STAT-4 N-domain0.00008059Direct
Thyroglobulin type-1 domain0.001601Inherited

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Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
57184,57610
  • 57184 - Growth factor receptor domain
  • 57610 - Thyroglobulin type-1 domain
  • 0.00003875Direct
    49417,55550
  • 49417 - p53-like transcription factors
  • 55550 - SH2 domain
  • 0.00008059Direct
    48092,47655
  • 48092 - Transcription factor STAT-4 N-domain
  • 47655 - STAT
  • 0.00008059Direct
    47655,49417
  • 47655 - STAT
  • 49417 - p53-like transcription factors
  • 0.00008059Direct
    57716,48508
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 48508 - Nuclear receptor ligand-binding domain
  • 0.0003689Direct

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    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    47655,49417,55550
  • 47655 - STAT
  • 49417 - p53-like transcription factors
  • 55550 - SH2 domain
  • 0.00008059Direct
    48092,47655,49417
  • 48092 - Transcription factor STAT-4 N-domain
  • 47655 - STAT
  • 49417 - p53-like transcription factors
  • 0.00008059Direct


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
    Plot tree as:   Download Newick format tree:
    (show help)