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Mammalian Phenotype (MP): abnormal sensitivity to induced morbidity/mortality

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Root: MP Hierarchy (mammalian/mouse phenotype from MGI_4.41)

Shortest distance to current term (+ for parents, - for children) MP term [MP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + 3:   mammalian phenotype [MP:0000001] <29>
+ + 2:   mortality/aging [MP:0010768] <4>(83|115) (89|67|50)
+ 1:   abnormal induced morbidity/mortality [MP:0001657] <5>(21|23) (21|9|3)
0:   abnormal sensitivity to induced morbidity/mortality [MP:0020148] <3>(16|20) (16|9|3)
- 1:   abnormal mortality induced by ionizing radiation [MP:0020149] <2>(6|6) (6|3|1)
- 1:   decreased sensitivity to induced morbidity/mortality [MP:0009764] <2>(1|1) (1|1|0)
- 1:   increased sensitivity to induced morbidity/mortality [MP:0009763] <1>(5|9) (5|5|2)


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Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
WGR domain-like0Direct
N-acetylmuramoyl-L-alanine amidase-like0Direct
Nitric oxide (NO) synthase oxygenase domain0Direct
Domain of poly(ADP-ribose) polymerase0.0002588Direct
Alpha-macroglobulin receptor domain0.0002725Direct
Flavoproteins0.0002725Direct
Ferredoxin reductase-like, C-terminal NADP-linked domain0.0002844Direct
Riboflavin synthase domain-like0.0002844Direct
Terpenoid cyclases/Protein prenyltransferases0.00178Inherited
GroES-like0.002097Inherited
BRCT domain0.002726Inherited
Ran binding protein zinc finger-like0.01262Inherited
ADP-ribosylation0.0439Inherited
SMAD/FHA domain0.08231Inherited
Nuclear receptor ligand-binding domain0.1862Inherited
Caspase-like0.5517Inherited


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Family

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SCOP termFDR (all)Annotation (direct or inherited)
N-acetylmuramoyl-L-alanine amidase-like0Direct
WGR domain0Direct
Nitric oxide (NO) synthase oxygenase domain0Direct
Cytochrome p450 reductase N-terminal domain-like0Direct
NADPH-cytochrome p450 reductase FAD-binding domain-like0.00001608Direct
NADPH-cytochrome p450 reductase-like0.00001608Direct
Tissue inhibitor of metalloproteinases, TIMP0.0001876Direct
Domain of poly(ADP-ribose) polymerase0.0001876Direct
Complement components0.0002101Direct
Alpha-macroglobulin receptor domain0.0002101Direct
Alcohol dehydrogenase-like, N-terminal domain0.001641Inherited
Alcohol dehydrogenase-like, C-terminal domain0.001641Inherited
Poly(ADP-ribose) polymerase, C-terminal domain0.00315Inherited
Ran binding protein zinc finger-like0.01114Inherited
FHA domain0.02941Inherited
Nuclear receptor ligand-binding domain0.1703Inherited
Nuclear receptor0.1703Inherited
PHD domain0.3826Inherited
Fibronectin type II module0.4506Inherited
Caspase catalytic domain0.5291Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
WGR domain-like0Direct
N-acetylmuramoyl-L-alanine amidase-like0Direct
Nitric oxide (NO) synthase oxygenase domain0Direct
Domain of poly(ADP-ribose) polymerase0.0001322Direct
Flavoproteins0.0001395Direct
Alpha-macroglobulin receptor domain0.0001395Direct
Riboflavin synthase domain-like0.0001461Direct
Ferredoxin reductase-like, C-terminal NADP-linked domain0.0001461Direct
Terpenoid cyclases/Protein prenyltransferases0.001007Inherited
GroES-like0.001195Inherited
BRCT domain0.001571Inherited
Ran binding protein zinc finger-like0.008016Inherited
ADP-ribosylation0.03067Inherited
SMAD/FHA domain0.06092Inherited
Nuclear receptor ligand-binding domain0.1509Inherited
Caspase-like0.5049Inherited

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Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
142921,47587
  • 142921 - WGR domain-like
  • 47587 - Domain of poly(ADP-ribose) polymerase
  • 0Direct
    51735,50129
  • 51735 - NAD(P)-binding Rossmann-fold domains
  • 50129 - GroES-like
  • 0Direct
    47587,56399
  • 47587 - Domain of poly(ADP-ribose) polymerase
  • 56399 - ADP-ribosylation
  • 0.0001322Direct
    57716,48508
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 48508 - Nuclear receptor ligand-binding domain
  • 0.0003875Direct
    50129,51735
  • 50129 - GroES-like
  • 51735 - NAD(P)-binding Rossmann-fold domains
  • 0.001195Inherited
    52113,52113
  • 52113 - BRCT domain
  • 52113 - BRCT domain
  • 0.002306Inherited
    52058,57184
  • 52058 - L domain-like
  • 57184 - Growth factor receptor domain
  • 0.002306Inherited
    57184,52058
  • 57184 - Growth factor receptor domain
  • 52058 - L domain-like
  • 0.002306Inherited
    47986,52129
  • 47986 - DEATH domain
  • 52129 - Caspase-like
  • 0.5049Inherited

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    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    50129,51735,50129
  • 50129 - GroES-like
  • 51735 - NAD(P)-binding Rossmann-fold domains
  • 50129 - GroES-like
  • 0Direct
    142921,47587,56399
  • 142921 - WGR domain-like
  • 47587 - Domain of poly(ADP-ribose) polymerase
  • 56399 - ADP-ribosylation
  • 0Direct
    52058,57184,52058
  • 52058 - L domain-like
  • 57184 - Growth factor receptor domain
  • 52058 - L domain-like
  • 0.002306Inherited


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
    Plot tree as:   Download Newick format tree:
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