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Worm Phenotype (WP): protein expression variant

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Root: WP Hierarchy (worm phenotype from Wormbase Release WS226)

Shortest distance to current term (+ for parents, - for children) WP term [WP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + + + + 6:   Variant [WBPhenotype:0000886] <2>
+ + + + + 5:   physiology variant [WBPhenotype:0000519] <15>(509|582) (509|247|68)
+ + + + 4:   organism physiology variant [WBPhenotype:0000576] <11>(366|425) (369|192|56)
+ + + 3:   organism homeostasis metabolism variant [WBPhenotype:0000577] <16>(358|416) (360|189|55)
+ + 2:   organism metabolism processing variant [WBPhenotype:0000027] <25>(176|187) (179|86|26)
+ 1:   gene expression variant [WBPhenotype:0000717] <10>(124|136) (127|63|20)
0:   protein expression variant [WBPhenotype:0000112] <6>(39|44) (39|19|6)
- 1:   protein modification variant [WBPhenotype:0001382] <9>(13|10) (13|3|0)
- 1:   antibody staining variant [WBPhenotype:0000424] <6>(5|5) (5|2|1)
- 1:   translation variant [WBPhenotype:0000121] <4>(0|0) (0|0|0)
- 1:   level of protein expression variant [WBPhenotype:0001400] <2>(11|12) (11|9|4)
- 1:   pattern protein expression variant [WBPhenotype:0001408] <2>(12|19) (12|6|2)
- 1:   electrophoretic variant protein [WBPhenotype:0000394](0|0) (0|0|0)


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Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
Heme-dependent catalase-like0Direct
14-3-3 protein0Direct
Protein kinase-like (PK-like)0.0000000002451Direct
Arginase/deacetylase0.0000000008277Direct
ARM repeat0.000000001528Direct
SH3-domain0.00000001019Direct
C2 domain (Calcium/lipid-binding domain, CaLB)0.00000003371Direct
Intermediate filament protein, coiled coil region0.00000118Direct
PH domain-like0.000002081Direct
SH2 domain0.00001249Direct
Lamin A/C globular tail domain0.00002425Direct
GTPase activation domain, GAP0.00005891Direct
Integrin domains0.0001571Direct
PX domain0.000356Direct
Cullin homology domain0.000356Direct
CAD & PB1 domains0.0006849Direct
ARID-like0.0006849Direct
PDZ domain-like0.000834Direct
DHS-like NAD/FAD-binding domain0.001218Inherited
Cullin repeat-like0.001975Inherited
Sm-like ribonucleoproteins0.002292Inherited
SET domain0.003103Inherited
Cysteine-rich domain0.004753Inherited
Second domain of FERM0.005044Inherited
Cyclin-like0.0106Inherited
Frizzled cysteine-rich domain0.01349Inherited
Activating enzymes of the ubiquitin-like proteins0.0168Inherited
Spectrin repeat0.0168Inherited
Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor0.0168Inherited
Riboflavin synthase domain-like0.09928Inherited
Ferredoxin reductase-like, C-terminal NADP-linked domain0.09928Inherited
Transducin (alpha subunit), insertion domain0.1475Inherited
Actin-like ATPase domain0.2069Inherited
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases0.2487Inherited
Clavaminate synthase-like0.254Inherited
"Winged helix" DNA-binding domain0.4437Inherited
FYVE/PHD zinc finger0.5902Inherited
Translation proteins0.9043Inherited
Chromo domain-like0.9348Inherited


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Family

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SCOP termFDR (all)Annotation (direct or inherited)
Sir2 family of transcriptional regulators0Direct
Phosphatidylinositol phosphate kinase IIbeta, PIPK IIbeta0Direct
Histone deacetylase, HDAC0Direct
Integrin domains0Direct
Inositol polyphosphate 5-phosphatase (IPP5)0Direct
14-3-3 protein0Direct
SCF ubiquitin ligase complex WHB domain0Direct
Phoshoinositide 3-kinase (PI3K) helical domain0Direct
Phoshoinositide 3-kinase (PI3K), catalytic domain0Direct
Cullin repeat0Direct
Heme-dependent catalases0Direct
SH3-domain0.00000002662Direct
Protein kinases, catalytic subunit0.000001721Direct
Intermediate filament protein, coiled coil region0.00000393Direct
EF-hand modules in multidomain proteins0.00002792Direct
PLC-like (P variant)0.00002917Direct
PDZ domain0.0001305Direct
SH2 domain0.0001309Direct
Lamin A/C globular tail domain0.0001744Direct
Pleckstrin-homology domain (PH domain)0.0002238Direct
PX domain0.0003367Direct
Cullin homology domain0.0003367Direct
LIM domain0.00113Inherited
Mammalian PLC0.00113Inherited
Histone lysine methyltransferases0.002183Inherited
First domain of FERM0.002917Inherited
Spectrin repeat0.00379Inherited
Third domain of FERM0.00379Inherited
Protein kinase cysteine-rich domain (cys2, phorbol-binding domain)0.004705Inherited
Pumilio repeat0.005555Inherited
Sm motif of small nuclear ribonucleoproteins, SNRNP0.006036Inherited
Second domain of FERM0.00747Inherited
Synaptotagmin-like (S variant)0.00747Inherited
Frizzled cysteine-rich domain0.01237Inherited
Armadillo repeat0.01441Inherited
Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor0.01588Inherited
G proteins0.01663Inherited
Actin/HSP700.1071Inherited
Extended AAA-ATPase domain0.1071Inherited
Transducin (alpha subunit), insertion domain0.1471Inherited
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases0.1642Inherited
Clathrin coat assembly domain0.1642Inherited
Elongation factors0.502Inherited
PHD domain0.5266Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
14-3-3 protein0Direct
Heme-dependent catalase-like0Direct
Protein kinase-like (PK-like)0.0000000001949Direct
Arginase/deacetylase0.0000000006593Direct
ARM repeat0.000000001219Direct
SH3-domain0.000000008156Direct
C2 domain (Calcium/lipid-binding domain, CaLB)0.00000002705Direct
Intermediate filament protein, coiled coil region0.0000009574Direct
PH domain-like0.000001692Direct
SH2 domain0.0000102Direct
Lamin A/C globular tail domain0.00001984Direct
GTPase activation domain, GAP0.00004831Direct
Integrin domains0.0001293Direct
Cullin homology domain0.0002946Direct
PX domain0.0002946Direct
CAD & PB1 domains0.0005696Direct
ARID-like0.0005696Direct
PDZ domain-like0.0006953Direct
DHS-like NAD/FAD-binding domain0.001018Inherited
Cullin repeat-like0.001659Inherited
Sm-like ribonucleoproteins0.00193Inherited
SET domain0.002623Inherited
Cysteine-rich domain0.004039Inherited
Second domain of FERM0.004291Inherited
Cyclin-like0.009133Inherited
Frizzled cysteine-rich domain0.01168Inherited
Spectrin repeat0.01458Inherited
Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor0.01458Inherited
Activating enzymes of the ubiquitin-like proteins0.01458Inherited
Ferredoxin reductase-like, C-terminal NADP-linked domain0.08975Inherited
Riboflavin synthase domain-like0.08975Inherited
Transducin (alpha subunit), insertion domain0.1346Inherited
Actin-like ATPase domain0.1908Inherited
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases0.2309Inherited
Clavaminate synthase-like0.2362Inherited
"Winged helix" DNA-binding domain0.4226Inherited
FYVE/PHD zinc finger0.5685Inherited
Translation proteins0.8892Inherited
Chromo domain-like0.9215Inherited

(show details)
Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
74788,75632
  • 74788 - Cullin repeat-like
  • 75632 - Cullin homology domain
  • 0Direct
    75632,46785
  • 75632 - Cullin homology domain
  • 46785 - "Winged helix" DNA-binding domain
  • 0Direct
    49562,48371
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 48371 - ARM repeat
  • 0Direct
    64593,74853
  • 64593 - Intermediate filament protein, coiled coil region
  • 74853 - Lamin A/C globular tail domain
  • 0.000006452Direct
    48371,56112
  • 48371 - ARM repeat
  • 56112 - Protein kinase-like (PK-like)
  • 0.00001162Direct
    57716,57716
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 0.00009144Direct
    55550,50044
  • 55550 - SH2 domain
  • 50044 - SH3-domain
  • 0.0001293Direct
    47031,50729
  • 47031 - Second domain of FERM
  • 50729 - PH domain-like
  • 0.0008684Direct
    50044,50044
  • 50044 - SH3-domain
  • 50044 - SH3-domain
  • 0.003478Inherited
    50044,55550
  • 50044 - SH3-domain
  • 55550 - SH2 domain
  • 0.003478Inherited
    54236,47031
  • 54236 - Ubiquitin-like
  • 47031 - Second domain of FERM
  • 0.00654Inherited
    46966,46966
  • 46966 - Spectrin repeat
  • 46966 - Spectrin repeat
  • 0.01168Inherited
    64356,49447
  • 64356 - SNARE-like
  • 49447 - Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor
  • 0.01168Inherited
    57196,57196
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.02054Inherited
    47954,47954
  • 47954 - Cyclin-like
  • 47954 - Cyclin-like
  • 0.02537Inherited
    57889,57889
  • 57889 - Cysteine-rich domain
  • 57889 - Cysteine-rich domain
  • 0.03673Inherited
    47895,52540
  • 47895 - Transducin (alpha subunit), insertion domain
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.1346Inherited
    53067,53067
  • 53067 - Actin-like ATPase domain
  • 53067 - Actin-like ATPase domain
  • 0.1908Inherited
    52540,50447
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 50447 - Translation proteins
  • 0.4789Inherited

    (show details)
    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    74788,75632,46785
  • 74788 - Cullin repeat-like
  • 75632 - Cullin homology domain
  • 46785 - "Winged helix" DNA-binding domain
  • 0Direct
    49562,48371,56112
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 48371 - ARM repeat
  • 56112 - Protein kinase-like (PK-like)
  • 0Direct
    57716,57716,57716
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 0.0002946Direct
    54236,47031,50729
  • 54236 - Ubiquitin-like
  • 47031 - Second domain of FERM
  • 50729 - PH domain-like
  • 0.004432Inherited
    46966,46966,46966
  • 46966 - Spectrin repeat
  • 46966 - Spectrin repeat
  • 46966 - Spectrin repeat
  • 0.01168Inherited
    57424,57424,57424
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 0.02015Inherited


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
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