SUPERFAMILY 1.75 HMM library and genome assignments server

Superfamily is undergoing a server migration - you are now browsing on the new server. Please contact us if you experience any problems.

Worm Phenotype (WP): chemical response variant

(show info)

Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Root: WP Hierarchy (worm phenotype from Wormbase Release WS226)

Shortest distance to current term (+ for parents, - for children) WP term [WP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + + + 5:   Variant [WBPhenotype:0000886] <2>
+ + + + 4:   physiology variant [WBPhenotype:0000519] <15>(509|582) (509|247|68)
+ + + 3:   organism physiology variant [WBPhenotype:0000576] <11>(366|425) (369|192|56)
+ + 2:   organism homeostasis metabolism variant [WBPhenotype:0000577] <16>(358|416) (360|189|55)
+ 1:   organism environmental stimulus response variant [WBPhenotype:0000738] <16>(128|115) (130|52|16)
0:   chemical response variant [WBPhenotype:0000523] <12>(67|60) (68|25|6)
- 1:   drug response variant [WBPhenotype:0000631] <27>(43|38) (44|16|2)
- 1:   chemical hypersensitive [WBPhenotype:0001918] <5>(7|7) (7|4|1)
- 1:   chemosensory behavior variant [WBPhenotype:0001049] <5>(19|19) (20|5|0)
- 1:   chemosensory response variant [WBPhenotype:0001040] <5>(19|19) (20|5|0)
- 1:   response to food variant [WBPhenotype:0001072] <4>(2|2) (2|0|0)
- 1:   chemical resistant [WBPhenotype:0001502] <2>(0|0) (0|0|0)
- 1:   bis phenol A response variant [WBPhenotype:0000931] <1>(0|0) (0|0|0)
- 1:   organism toxic chemical response variant [WBPhenotype:0001379] <1>(0|0) (0|0|0)
- 1:   growth inhibition response to chemical [WBPhenotype:0002125](0|0) (0|0|0)
- 1:   high pH avoidance defective [WBPhenotype:0002385](0|0) (0|0|0)
- 1:   neurotransmitter response variant [WBPhenotype:0002399](0|0) (0|0|0)
- 1:   unfolded protein response variant [WBPhenotype:0001719](6|5) (6|4|2)


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Superfamily

(show details)
SCOP termFDR (all)Annotation (direct or inherited)
Aromatic aminoacid monoxygenases, catalytic and oligomerization domains0Direct
Transducin (heterotrimeric G protein), gamma chain0Direct
Skp1 dimerisation domain-like0.0000000000009406Direct
Nicotinic receptor ligand binding domain-like0.000000000001228Direct
Neurotransmitter-gated ion-channel transmembrane pore0.000000000002387Direct
Cullin repeat-like0.000000009891Direct
Cullin homology domain0.0000007544Direct
Protein kinase-like (PK-like)0.0000009624Direct
cAMP-binding domain-like0.00001046Direct
C2 domain (Calcium/lipid-binding domain, CaLB)0.00001394Direct
Transducin (alpha subunit), insertion domain0.0002654Direct
Periplasmic binding protein-like I0.002462Inherited
Myosin rod fragments0.003839Inherited
Quinoprotein alcohol dehydrogenase-like0.007825Inherited
Voltage-gated potassium channels0.01824Inherited
Multidrug efflux transporter AcrB transmembrane domain0.0217Inherited
EF-hand0.02244Inherited
Tryptophan synthase beta subunit-like PLP-dependent enzymes0.02287Inherited
Immunoglobulin0.02522Inherited
PRTase-like0.02693Inherited
Lipovitellin-phosvitin complex; beta-sheet shell regions0.03135Inherited
Spectrin repeat0.03135Inherited
Lipovitellin-phosvitin complex, superhelical domain0.03135Inherited
ENTH/VHS domain0.03137Inherited
TPR-like0.03146Inherited
Calcium ATPase, transmembrane domain M0.03687Inherited
Calcium ATPase, transduction domain A0.03687Inherited
Metal cation-transporting ATPase, ATP-binding domain N0.03687Inherited
Periplasmic binding protein-like II0.03784Inherited
PDZ domain-like0.04229Inherited
WD40 repeat-like0.0456Inherited
Troponin coil-coiled subunits0.05919Inherited
SMAD/FHA domain0.05989Inherited
Glutathione synthetase ATP-binding domain-like0.05989Inherited
SAM/Pointed domain0.06482Inherited
Regulator of G-protein signaling, RGS0.06482Inherited
Nucleotide cyclase0.06505Inherited
Cysteine-rich domain0.06797Inherited
EGF/Laminin0.08499Inherited
SH3-domain0.1106Inherited
t-snare proteins0.1108Inherited
SNARE-like0.1148Inherited
SNF-like0.1797Inherited
PH domain-like0.2133Inherited
P-loop containing nucleoside triphosphate hydrolases0.2219Inherited
Cystine-knot cytokines0.2225Inherited
GroEL equatorial domain-like0.2274Inherited
GroEL-intermediate domain like0.2274Inherited
GroEL apical domain-like0.2274Inherited
Tubulin nucleotide-binding domain-like0.262Inherited
HAD-like0.2669Inherited
POZ domain0.2708Inherited
Bromodomain0.334Inherited
Tubulin C-terminal domain-like0.3887Inherited
Sm-like ribonucleoproteins0.4719Inherited
"Winged helix" DNA-binding domain0.48Inherited
ABC transporter transmembrane region0.6253Inherited
Leucine zipper domain0.6309Inherited
Glucocorticoid receptor-like (DNA-binding domain)0.6983Inherited
Homeodomain-like0.8081Inherited
DBL homology domain (DH-domain)0.8339Inherited
Nucleic acid-binding proteins0.8566Inherited
HLH, helix-loop-helix DNA-binding domain0.9049Inherited
Nuclear receptor ligand-binding domain1Inherited
Ankyrin repeat1Inherited
Family A G protein-coupled receptor-like1Inherited
beta-beta-alpha zinc fingers1Inherited


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Family

(show details)
SCOP termFDR (all)Annotation (direct or inherited)
Transducin (heterotrimeric G protein), gamma chain0Direct
Quinoprotein alcohol dehydrogenase-like0Direct
SCF ubiquitin ligase complex WHB domain0Direct
Cullin repeat0Direct
Aromatic aminoacid monoxygenases, catalytic and oligomerization domains0Direct
Neurotransmitter-gated ion-channel transmembrane pore0.000000000007123Direct
Nicotinic receptor ligand binding domain-like0.000000000007123Direct
Skp1 dimerisation domain-like0.0000000001108Direct
Protein kinases, catalytic subunit0.0000002225Direct
Cullin homology domain0.000002233Direct
cAMP-binding domain0.00001692Direct
Transducin (alpha subunit), insertion domain0.0003371Direct
DNA replication initiator (cdc21/cdc54) N-terminal domain0.0005541Direct
Eps15 homology domain (EH domain)0.0007548Direct
BTB/POZ domain0.001715Inherited
Transforming growth factor (TGF)-beta0.003158Inherited
PLC-like (P variant)0.004607Inherited
Synaptotagmin-like (S variant)0.006387Inherited
G proteins0.01033Inherited
L-arabinose binding protein-like0.01278Inherited
I set domains0.01302Inherited
Clathrin coat assembly domain0.01605Inherited
Phosphoribosyltransferases (PRTases)0.01605Inherited
Multidrug efflux transporter AcrB transmembrane domain0.02276Inherited
Spectrin repeat0.0311Inherited
Lipovitellin-phosvitin complex; beta-sheet shell regions0.0311Inherited
Lipovitellin-phosvitin complex, superhelical domain0.0311Inherited
Pleckstrin-homology domain (PH domain)0.0377Inherited
Phosphate binding protein-like0.03905Inherited
Calcium ATPase, transduction domain A0.03932Inherited
Metal cation-transporting ATPase, ATP-binding domain N0.03932Inherited
PDZ domain0.03932Inherited
Tryptophan synthase beta subunit-like PLP-dependent enzymes0.04116Inherited
Regulator of G-protein signaling, RGS0.0662Inherited
Adenylyl and guanylyl cyclase catalytic domain0.07647Inherited
Meta-cation ATPase, catalytic domain P0.09926Inherited
t-snare proteins0.1078Inherited
Group II chaperonin (CCT, TRIC), intermediate domain0.1078Inherited
SH3-domain0.1245Inherited
Protein kinase cysteine-rich domain (cys2, phorbol-binding domain)0.1296Inherited
WD40-repeat0.1634Inherited
SNF-like0.1799Inherited
Pyridoxal-dependent decarboxylase0.1799Inherited
Voltage-gated potassium channels0.2009Inherited
Calcium ATPase, transmembrane domain M0.2318Inherited
Tubulin, GTPase domain0.2713Inherited
FYVE, a phosphatidylinositol-3-phosphate binding domain0.2859Inherited
Group II chaperonin (CCT, TRIC), ATPase domain0.339Inherited
Group II chaperonin (CCT, TRIC), apical domain0.339Inherited
Bromodomain0.339Inherited
Tubulin, C-terminal domain0.4017Inherited
Leucine zipper domain0.6477Inherited
Rhodopsin-like0.7108Inherited
ABC transporter transmembrane region0.7465Inherited
DBL homology domain (DH-domain)0.8488Inherited
ABC transporter ATPase domain-like0.8659Inherited
HLH, helix-loop-helix DNA-binding domain0.9153Inherited
Nuclear receptor ligand-binding domain1Inherited
Ankyrin repeat1Inherited
Nuclear receptor1Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
Plot tree as:   Download Newick format tree:
(show help)

Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

(show details)
Supra-domain (Single) FDR (all) Annotation (direct or inherited)
Aromatic aminoacid monoxygenases, catalytic and oligomerization domains0Direct
Transducin (heterotrimeric G protein), gamma chain0Direct
Skp1 dimerisation domain-like0.0000000000007435Direct
Nicotinic receptor ligand binding domain-like0.0000000000009712Direct
Neurotransmitter-gated ion-channel transmembrane pore0.000000000001889Direct
Cullin repeat-like0.000000007914Direct
Cullin homology domain0.0000006109Direct
Protein kinase-like (PK-like)0.0000007801Direct
cAMP-binding domain-like0.00000853Direct
C2 domain (Calcium/lipid-binding domain, CaLB)0.00001139Direct
Transducin (alpha subunit), insertion domain0.0002193Direct
Periplasmic binding protein-like I0.002076Inherited
Myosin rod fragments0.003255Inherited
Quinoprotein alcohol dehydrogenase-like0.006707Inherited
Voltage-gated potassium channels0.01583Inherited
Multidrug efflux transporter AcrB transmembrane domain0.01892Inherited
EF-hand0.01958Inherited
Tryptophan synthase beta subunit-like PLP-dependent enzymes0.01997Inherited
Immunoglobulin0.02207Inherited
PRTase-like0.0236Inherited
Spectrin repeat0.02756Inherited
Lipovitellin-phosvitin complex; beta-sheet shell regions0.02756Inherited
Lipovitellin-phosvitin complex, superhelical domain0.02756Inherited
ENTH/VHS domain0.02758Inherited
TPR-like0.02767Inherited
Calcium ATPase, transduction domain A0.03253Inherited
Metal cation-transporting ATPase, ATP-binding domain N0.03253Inherited
Calcium ATPase, transmembrane domain M0.03253Inherited
Periplasmic binding protein-like II0.0334Inherited
PDZ domain-like0.03739Inherited
WD40 repeat-like0.04039Inherited
Troponin coil-coiled subunits0.05273Inherited
Glutathione synthetase ATP-binding domain-like0.05338Inherited
SMAD/FHA domain0.05338Inherited
Regulator of G-protein signaling, RGS0.05786Inherited
SAM/Pointed domain0.05786Inherited
Nucleotide cyclase0.05809Inherited
Cysteine-rich domain0.06076Inherited
EGF/Laminin0.07653Inherited
SH3-domain0.1001Inherited
t-snare proteins0.1003Inherited
SNARE-like0.1041Inherited
SNF-like0.165Inherited
PH domain-like0.197Inherited
P-loop containing nucleoside triphosphate hydrolases0.2052Inherited
Cystine-knot cytokines0.2058Inherited
WW domain0.2105Inherited
GroEL apical domain-like0.2105Inherited
GroEL equatorial domain-like0.2105Inherited
GroEL-intermediate domain like0.2105Inherited
Tubulin nucleotide-binding domain-like0.244Inherited
HAD-like0.2488Inherited
POZ domain0.2525Inherited
Bromodomain0.3142Inherited
Tubulin C-terminal domain-like0.3681Inherited
Sm-like ribonucleoproteins0.4507Inherited
"Winged helix" DNA-binding domain0.4589Inherited
ABC transporter transmembrane region0.6035Inherited
Leucine zipper domain0.6092Inherited
Glucocorticoid receptor-like (DNA-binding domain)0.6775Inherited
Homeodomain-like0.7897Inherited
DBL homology domain (DH-domain)0.8163Inherited
Nucleic acid-binding proteins0.8402Inherited
HLH, helix-loop-helix DNA-binding domain0.8899Inherited
Family A G protein-coupled receptor-like1Inherited
Nuclear receptor ligand-binding domain1Inherited
Ankyrin repeat1Inherited
beta-beta-alpha zinc fingers1Inherited

(show details)
Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
74788,75632
  • 74788 - Cullin repeat-like
  • 75632 - Cullin homology domain
  • 0Direct
    75632,46785
  • 75632 - Cullin homology domain
  • 46785 - "Winged helix" DNA-binding domain
  • 0Direct
    63712,90112
  • 63712 - Nicotinic receptor ligand binding domain-like
  • 90112 - Neurotransmitter-gated ion-channel transmembrane pore
  • 0.000000000001889Direct
    54695,81382
  • 54695 - POZ domain
  • 81382 - Skp1 dimerisation domain-like
  • 0.00000000003856Direct
    56112,55073
  • 56112 - Protein kinase-like (PK-like)
  • 55073 - Nucleotide cyclase
  • 0.0000001014Direct
    47895,52540
  • 47895 - Transducin (alpha subunit), insertion domain
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.0002193Direct
    48452,48452
  • 48452 - TPR-like
  • 48452 - TPR-like
  • 0.000255Direct
    49265,48726
  • 49265 - Fibronectin type III
  • 48726 - Immunoglobulin
  • 0.0003767Direct
    48726,49265
  • 48726 - Immunoglobulin
  • 49265 - Fibronectin type III
  • 0.0005462Direct
    50044,50044
  • 50044 - SH3-domain
  • 50044 - SH3-domain
  • 0.0007086Direct
    49562,49562
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 0.01997Inherited
    56968,48431
  • 56968 - Lipovitellin-phosvitin complex; beta-sheet shell regions
  • 48431 - Lipovitellin-phosvitin complex, superhelical domain
  • 0.02756Inherited
    47473,47473
  • 47473 - EF-hand
  • 47473 - EF-hand
  • 0.02756Inherited
    48431,56968
  • 48431 - Lipovitellin-phosvitin complex, superhelical domain
  • 56968 - Lipovitellin-phosvitin complex; beta-sheet shell regions
  • 0.02756Inherited
    81660,56784
  • 81660 - Metal cation-transporting ATPase, ATP-binding domain N
  • 56784 - HAD-like
  • 0.03253Inherited
    46966,46966
  • 46966 - Spectrin repeat
  • 46966 - Spectrin repeat
  • 0.05273Inherited
    50978,50978
  • 50978 - WD40 repeat-like
  • 50978 - WD40 repeat-like
  • 0.05273Inherited
    56784,81665
  • 56784 - HAD-like
  • 81665 - Calcium ATPase, transmembrane domain M
  • 0.05338Inherited
    57889,57889
  • 57889 - Cysteine-rich domain
  • 57889 - Cysteine-rich domain
  • 0.165Inherited
    48592,54849
  • 48592 - GroEL equatorial domain-like
  • 54849 - GroEL-intermediate domain like
  • 0.2105Inherited
    54849,52029
  • 54849 - GroEL-intermediate domain like
  • 52029 - GroEL apical domain-like
  • 0.2105Inherited
    52490,55307
  • 52490 - Tubulin nucleotide-binding domain-like
  • 55307 - Tubulin C-terminal domain-like
  • 0.244Inherited
    90123,52540
  • 90123 - ABC transporter transmembrane region
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.6035Inherited
    48065,50729
  • 48065 - DBL homology domain (DH-domain)
  • 50729 - PH domain-like
  • 0.7359Inherited
    57716,48508
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 48508 - Nuclear receptor ligand-binding domain
  • 0.9377Inherited

    (show details)
    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    74788,75632,46785
  • 74788 - Cullin repeat-like
  • 75632 - Cullin homology domain
  • 46785 - "Winged helix" DNA-binding domain
  • 0Direct
    52540,52540,52540
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.0003767Direct
    56968,48431,56968
  • 56968 - Lipovitellin-phosvitin complex; beta-sheet shell regions
  • 48431 - Lipovitellin-phosvitin complex, superhelical domain
  • 56968 - Lipovitellin-phosvitin complex; beta-sheet shell regions
  • 0.02756Inherited
    81660,56784,81665
  • 81660 - Metal cation-transporting ATPase, ATP-binding domain N
  • 56784 - HAD-like
  • 81665 - Calcium ATPase, transmembrane domain M
  • 0.05338Inherited
    46966,46966,46966
  • 46966 - Spectrin repeat
  • 46966 - Spectrin repeat
  • 46966 - Spectrin repeat
  • 0.1003Inherited
    48592,54849,52029
  • 48592 - GroEL equatorial domain-like
  • 54849 - GroEL-intermediate domain like
  • 52029 - GroEL apical domain-like
  • 0.2105Inherited


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
    Plot tree as:   Download Newick format tree:
    (show help)