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Worm Phenotype (WP): metal response variant

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Root: WP Hierarchy (worm phenotype from Wormbase Release WS226)

Shortest distance to current term (+ for parents, - for children) WP term [WP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + + + 5:   Variant [WBPhenotype:0000886] <4>
+ + + + 4:   physiology variant [WBPhenotype:0000519] <7>(487|558) (487|240|64)
+ + + 3:   organism physiology variant [WBPhenotype:0000576] <10>(355|415) (355|191|56)
+ + 2:   organism homeostasis metabolism variant [WBPhenotype:0000577] <17>(346|406) (348|189|55)
+ 1:   organism environmental stimulus response variant [WBPhenotype:0000738] <16>(115|103) (118|51|16)
0:   metal response variant [WBPhenotype:0000591] <15>(12|13) (13|10|5)
- 1:   cadmium response variant [WBPhenotype:0001653] <2>(9|10) (10|9|5)
- 1:   copper response variant [WBPhenotype:0000592] <2>(0|1) (1|0|0)
- 1:   manganese response variant [WBPhenotype:0001863] <2>(1|1) (1|0|0)
- 1:   zinc response variant [WBPhenotype:0001747] <2>(0|0) (0|0|0)
- 1:   lead response variant [WBPhenotype:0002227] <1>(0|0) (0|0|0)
- 1:   silver hypersensitive [WBPhenotype:0002250] <1>(0|0) (0|0|0)
- 1:   aluminum response variant [WBPhenotype:0002228](0|0) (0|0|0)
- 1:   arsenic hypersensitive [WBPhenotype:0002244](0|0) (0|0|0)
- 1:   chromium response variant [WBPhenotype:0002229](0|0) (0|0|0)
- 1:   cobalt hypersensitive [WBPhenotype:0002226](0|0) (0|0|0)
- 1:   iron hypersensitive [WBPhenotype:0002257](0|0) (0|0|0)
- 1:   magnesium hypersensitivity [WBPhenotype:0002054](0|0) (0|0|0)
- 1:   mercury hypersensitive [WBPhenotype:0002224](0|0) (0|0|0)
- 1:   nickel toxicity resistant [WBPhenotype:0002258](0|0) (0|0|0)
- 1:   selenium response variant [WBPhenotype:0002256](2|2) (2|1|0)


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Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
ABC transporter transmembrane region0.000000007699Direct
Cation efflux protein transmembrane domain-like0.0000000156Direct
Cation efflux protein cytoplasmic domain-like0.00000383Direct
Protein kinase-like (PK-like)0.00004256Direct
Cytochrome P4500.0002677Direct
GST C-terminal domain-like0.0008739Direct
Thioredoxin-like0.001573Inherited
HSP20-like chaperones0.0027Inherited
Heat shock protein 70kD (HSP70), C-terminal subdomain0.005589Inherited
Heat shock protein 70kD (HSP70), peptide-binding domain0.005589Inherited
Neurotransmitter-gated ion-channel transmembrane pore0.3074Inherited
Nicotinic receptor ligand binding domain-like0.3235Inherited


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Family

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SCOP termFDR (all)Annotation (direct or inherited)
ABC transporter transmembrane region0.000000003127Direct
ABC transporter ATPase domain-like0.0000002748Direct
Cation efflux protein transmembrane domain-like0.0000005073Direct
Cation efflux protein cytoplasmic domain-like0.000002233Direct
Cytochrome P4500.0003863Direct
Protein kinases, catalytic subunit0.000871Direct
Glutathione S-transferase (GST), N-terminal domain0.001376Inherited
Glutathione S-transferase (GST), C-terminal domain0.001818Inherited
Heat shock protein 70kD (HSP70), peptide-binding domain0.002739Inherited
Heat shock protein 70kD (HSP70), C-terminal subdomain0.004984Inherited
Actin/HSP700.04144Inherited
Neurotransmitter-gated ion-channel transmembrane pore0.3061Inherited
Nicotinic receptor ligand binding domain-like0.3061Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
ABC transporter transmembrane region0.00000000618Direct
Cation efflux protein transmembrane domain-like0.00000001253Direct
Cation efflux protein cytoplasmic domain-like0.000003131Direct
Protein kinase-like (PK-like)0.00003502Direct
Cytochrome P4500.0002217Direct
GST C-terminal domain-like0.0007316Direct
Thioredoxin-like0.001323Inherited
HSP20-like chaperones0.002283Inherited
Heat shock protein 70kD (HSP70), C-terminal subdomain0.004765Inherited
Heat shock protein 70kD (HSP70), peptide-binding domain0.004765Inherited
Actin-like ATPase domain0.07312Inherited
Neurotransmitter-gated ion-channel transmembrane pore0.2879Inherited
Nicotinic receptor ligand binding domain-like0.3038Inherited

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Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
90123,52540
  • 90123 - ABC transporter transmembrane region
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.00000000618Direct
    161111,160240
  • 161111 - Cation efflux protein transmembrane domain-like
  • 160240 - Cation efflux protein cytoplasmic domain-like
  • 0.000003131Direct
    52540,90123
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 90123 - ABC transporter transmembrane region
  • 0.000009071Direct
    52833,47616
  • 52833 - Thioredoxin-like
  • 47616 - GST C-terminal domain-like
  • 0.0002487Direct
    56436,49854
  • 56436 - C-type lectin-like
  • 49854 - Spermadhesin, CUB domain
  • 0.002552Inherited
    100920,100934
  • 100920 - Heat shock protein 70kD (HSP70), peptide-binding domain
  • 100934 - Heat shock protein 70kD (HSP70), C-terminal subdomain
  • 0.004765Inherited
    53067,100920
  • 53067 - Actin-like ATPase domain
  • 100920 - Heat shock protein 70kD (HSP70), peptide-binding domain
  • 0.004765Inherited
    56436,56436
  • 56436 - C-type lectin-like
  • 56436 - C-type lectin-like
  • 0.005935Inherited
    53067,53067
  • 53067 - Actin-like ATPase domain
  • 53067 - Actin-like ATPase domain
  • 0.06068Inherited
    63712,90112
  • 63712 - Nicotinic receptor ligand binding domain-like
  • 90112 - Neurotransmitter-gated ion-channel transmembrane pore
  • 0.2879Inherited

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    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    52540,90123,52540
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 90123 - ABC transporter transmembrane region
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.000009071Direct
    90123,52540,90123
  • 90123 - ABC transporter transmembrane region
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 90123 - ABC transporter transmembrane region
  • 0.000009071Direct
    56436,56436,49854
  • 56436 - C-type lectin-like
  • 56436 - C-type lectin-like
  • 49854 - Spermadhesin, CUB domain
  • 0.001032Inherited
    53067,53067,100920
  • 53067 - Actin-like ATPase domain
  • 53067 - Actin-like ATPase domain
  • 100920 - Heat shock protein 70kD (HSP70), peptide-binding domain
  • 0.004765Inherited
    53067,100920,100934
  • 53067 - Actin-like ATPase domain
  • 100920 - Heat shock protein 70kD (HSP70), peptide-binding domain
  • 100934 - Heat shock protein 70kD (HSP70), C-terminal subdomain
  • 0.004765Inherited


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
    Plot tree as:   Download Newick format tree:
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