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Worm Phenotype (WP): locomotion variant

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Root: WP Hierarchy (worm phenotype from Wormbase Release WS226)

Shortest distance to current term (+ for parents, - for children) WP term [WP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + + 4:   Variant [WBPhenotype:0000886] <2>
+ + + 3:   physiology variant [WBPhenotype:0000519] <15>(509|582) (509|247|68)
+ + 2:   behavior variant [WBPhenotype:0000517] <3>(136|138) (138|59|22)
+ 1:   organism behavior variant [WBPhenotype:0000525] <22>(136|138) (138|59|22)
0:   locomotion variant [WBPhenotype:0000643] <10>(73|80) (74|32|15)
- 1:   locomotor coordination variant [WBPhenotype:0004017] <7>(19|22) (19|7|1)
- 1:   activity level variant [WBPhenotype:0000641] <6>(22|26) (23|11|5)
- 1:   cell migration variant [WBPhenotype:0000594] <6>(24|24) (24|6|1)
- 1:   localized movement variant [WBPhenotype:0001699] <3>(13|14) (13|5|1)
- 1:   swimming variant [WBPhenotype:0001700] <3>(0|2) (1|0|0)
- 1:   chemotaxis variant [WBPhenotype:0001434] <2>(19|18) (20|5|0)
- 1:   forward locomotion variant [WBPhenotype:0002345] <2>(12|14) (12|4|0)
- 1:   burrowing assay distance abnormal [WBPhenotype:0002516] <1>(1|0) (1|0|0)
- 1:   thermotaxis variant [WBPhenotype:0002513] <1>(6|6) (6|1|0)
- 1:   enhanced locomotion defective [WBPhenotype:0001773](0|0) (0|0|0)


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Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
Heat shock protein 70kD (HSP70), peptide-binding domain0Direct
Heat shock protein 70kD (HSP70), C-terminal subdomain0Direct
HSP90 C-terminal domain0Direct
5' to 3' exonuclease, C-terminal subdomain0Direct
S-adenosylmethionine synthetase0Direct
Multidrug efflux transporter AcrB transmembrane domain0Direct
Transducin (heterotrimeric G protein), gamma chain0Direct
Integrin alpha N-terminal domain0Direct
HSP40/DnaJ peptide-binding domain0Direct
Clathrin adaptor appendage domain0Direct
DnaJ/Hsp40 cysteine-rich domain0Direct
Frizzled cysteine-rich domain0Direct
Chaperone J-domain0Direct
WWE domain0Direct
Subdomain of clathrin and coatomer appendage domain0Direct
Transducin (alpha subunit), insertion domain0.000000000000002668Direct
RING/U-box0.00000000000006363Direct
Skp1 dimerisation domain-like0.000000000001047Direct
Hect, E3 ligase catalytic domain0.000002139Direct
Tubulin C-terminal domain-like0.000003772Direct
Nicotinic receptor ligand binding domain-like0.000009357Direct
Neurotransmitter-gated ion-channel transmembrane pore0.0000129Direct
Tubulin nucleotide-binding domain-like0.00001378Direct
SNF-like0.00001378Direct
B-box zinc-binding domain0.00008819Direct
Periplasmic binding protein-like I0.0001196Direct
Smc hinge domain0.0002209Direct
Hedgehog/intein (Hint) domain0.0002744Direct
Spectrin repeat0.0007861Direct
UBC-like0.0008968Direct
cAMP-binding domain-like0.001259Inherited
Insulin-like0.002424Inherited
Cysteine proteinases0.002545Inherited
Integrin domains0.004487Inherited
E2F-DP heterodimerization region0.004487Inherited
EGF/Laminin0.004697Inherited
Cysteine-rich domain0.006459Inherited
TPR-like0.007571Inherited
Periplasmic binding protein-like II0.01157Inherited
Immunoglobulin0.0135Inherited
Fibronectin type III0.01455Inherited
WD40 repeat-like0.04162Inherited
Myosin rod fragments0.0446Inherited
Glutathione synthetase ATP-binding domain-like0.04745Inherited
BAR/IMD domain-like0.06877Inherited
NAD kinase/diacylglycerol kinase-like0.07049Inherited
PH domain-like0.07765Inherited
Tropomyosin0.1128Inherited
NHL repeat0.141Inherited
UBA-like0.2025Inherited
Lamin A/C globular tail domain0.2073Inherited
Intermediate filament protein, coiled coil region0.2073Inherited
Second domain of FERM0.2073Inherited
Ankyrin repeat0.2407Inherited
Nucleotide cyclase0.2412Inherited
HD-domain/PDEase-like0.2784Inherited
Voltage-gated potassium channels0.3015Inherited
PX domain0.3348Inherited
RCC1/BLIP-II0.3723Inherited
Protein kinase-like (PK-like)0.3745Inherited
PapD-like0.3854Inherited
Regulator of G-protein signaling, RGS0.3937Inherited
HLH, helix-loop-helix DNA-binding domain0.5545Inherited
Homeodomain-like0.561Inherited
SMAD MH1 domain0.5776Inherited
PLP-dependent transferases0.5823Inherited
LDL receptor-like module0.6232Inherited
Troponin coil-coiled subunits0.7135Inherited
SMAD/FHA domain0.9196Inherited
POZ domain0.9735Inherited
P-loop containing nucleoside triphosphate hydrolases0.9735Inherited
Glucocorticoid receptor-like (DNA-binding domain)1Inherited
C2 domain (Calcium/lipid-binding domain, CaLB)1Inherited


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Family

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SCOP termFDR (all)Annotation (direct or inherited)
Transducin (heterotrimeric G protein), gamma chain0Direct
Ubiquitin carboxyl-terminal hydrolase UCH-L0Direct
Phoshatidylinositol transfer protein, PITP0Direct
Frizzled cysteine-rich domain0Direct
5' to 3' exonuclease catalytic domain0Direct
Laminin-type module0Direct
HSP40/DnaJ peptide-binding domain0Direct
HSP90 C-terminal domain0Direct
Hsp90 middle domain0Direct
Heat shock protein 70kD (HSP70), C-terminal subdomain0Direct
RhoGDI-like0Direct
DnaJ/Hsp40 cysteine-rich domain0Direct
Quinoprotein alcohol dehydrogenase-like0Direct
Myotubularin-like phosphatases0Direct
Integrin domains0Direct
Smc hinge domain0Direct
Heat shock protein 90, HSP90, N-terminal domain0Direct
Heat shock protein 70kD (HSP70), peptide-binding domain0Direct
5' to 3' exonuclease, C-terminal subdomain0Direct
Chaperone J-domain0Direct
HSP200Direct
Zf-UBP0Direct
S-adenosylmethionine synthetase0Direct
WWE domain0Direct
Multidrug efflux transporter AcrB transmembrane domain0.00000000000001682Direct
Transducin (alpha subunit), insertion domain0.00000000000008424Direct
Skp1 dimerisation domain-like0.000000000001421Direct
Ubiquitin carboxyl-terminal hydrolase, UCH0.0000000003118Direct
UBC-related0.00000002024Direct
Neurotransmitter-gated ion-channel transmembrane pore0.00000085Direct
Hect, E3 ligase catalytic domain0.000007304Direct
Nicotinic receptor ligand binding domain-like0.00001104Direct
Tubulin, C-terminal domain0.00002132Direct
SNF-like0.00002175Direct
Tubulin, GTPase domain0.00006584Direct
Rhodopsin-like0.000122Direct
B-box zinc-binding domain0.0003843Direct
Reprolysin-like0.0006872Direct
Spectrin repeat0.000732Direct
Hedgehog C-terminal (Hog) autoprocessing domain0.000732Direct
L-arabinose binding protein-like0.0007439Direct
RING finger domain, C3HC40.0008759Direct
cAMP-binding domain0.001661Inherited
Insulin-like0.00202Inherited
Cell cycle transcription factor e2f-dp0.006832Inherited
Phosphate binding protein-like0.009021Inherited
Fibronectin type III0.01256Inherited
I set domains0.02022Inherited
EGF-type module0.02626Inherited
Protein kinase cysteine-rich domain (cys2, phorbol-binding domain)0.02798Inherited
G proteins0.04151Inherited
BTB/POZ domain0.05101Inherited
First domain of FERM0.05795Inherited
NHL repeat0.0729Inherited
Myosin rod fragments0.0729Inherited
WD40-repeat0.07987Inherited
Tropomyosin0.1007Inherited
Third domain of FERM0.1123Inherited
Intermediate filament protein, coiled coil region0.189Inherited
Adenylyl and guanylyl cyclase catalytic domain0.2269Inherited
Protein kinases, catalytic subunit0.2503Inherited
Second domain of FERM0.2514Inherited
Lamin A/C globular tail domain0.2577Inherited
Pyridoxal-dependent decarboxylase0.2577Inherited
PDEase0.2577Inherited
Pleckstrin-homology domain (PH domain)0.3052Inherited
Voltage-gated potassium channels0.3327Inherited
Regulator of G-protein signaling, RGS0.3726Inherited
PX domain0.442Inherited
MSP-like0.4501Inherited
Homeodomain0.4657Inherited
Ankyrin repeat0.5264Inherited
HLH, helix-loop-helix DNA-binding domain0.538Inherited
SMAD MH1 domain0.5548Inherited
LDL receptor-like module0.6031Inherited
Integrin A (or I) domain0.6234Inherited
SMAD domain0.7841Inherited
PLC-like (P variant)0.861Inherited
Acetylcholinesterase-like0.9821Inherited
Synaptotagmin-like (S variant)1Inherited


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Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
5' to 3' exonuclease, C-terminal subdomain0Direct
WWE domain0Direct
Subdomain of clathrin and coatomer appendage domain0Direct
Clathrin adaptor appendage domain0Direct
HSP90 C-terminal domain0Direct
DnaJ/Hsp40 cysteine-rich domain0Direct
Integrin alpha N-terminal domain0Direct
S-adenosylmethionine synthetase0Direct
Heat shock protein 70kD (HSP70), C-terminal subdomain0Direct
Transducin (heterotrimeric G protein), gamma chain0Direct
Heat shock protein 70kD (HSP70), peptide-binding domain0Direct
Multidrug efflux transporter AcrB transmembrane domain0Direct
Frizzled cysteine-rich domain0Direct
HSP40/DnaJ peptide-binding domain0Direct
Chaperone J-domain0Direct
Transducin (alpha subunit), insertion domain0.000000000000002099Direct
RING/U-box0.00000000000005016Direct
Skp1 dimerisation domain-like0.0000000000008278Direct
Hect, E3 ligase catalytic domain0.000001739Direct
Tubulin C-terminal domain-like0.000003072Direct
Nicotinic receptor ligand binding domain-like0.000007629Direct
Neurotransmitter-gated ion-channel transmembrane pore0.00001053Direct
SNF-like0.00001125Direct
Tubulin nucleotide-binding domain-like0.00001125Direct
B-box zinc-binding domain0.00007243Direct
Periplasmic binding protein-like I0.00009838Direct
Smc hinge domain0.0001822Direct
Hedgehog/intein (Hint) domain0.0002267Direct
Spectrin repeat0.0006552Direct
UBC-like0.0007477Direct
cAMP-binding domain-like0.001053Inherited
Insulin-like0.002044Inherited
Cysteine proteinases0.002147Inherited
E2F-DP heterodimerization region0.00381Inherited
Integrin domains0.00381Inherited
EGF/Laminin0.00399Inherited
Cysteine-rich domain0.005516Inherited
TPR-like0.006484Inherited
Periplasmic binding protein-like II0.009981Inherited
Immunoglobulin0.01168Inherited
Fibronectin type III0.01261Inherited
WD40 repeat-like0.03678Inherited
Myosin rod fragments0.03948Inherited
Glutathione synthetase ATP-binding domain-like0.04207Inherited
BAR/IMD domain-like0.06149Inherited
NAD kinase/diacylglycerol kinase-like0.06308Inherited
PH domain-like0.06968Inherited
Tropomyosin0.1022Inherited
NHL repeat0.1285Inherited
UBA-like0.1866Inherited
Lamin A/C globular tail domain0.1912Inherited
Second domain of FERM0.1912Inherited
Intermediate filament protein, coiled coil region0.1912Inherited
Ankyrin repeat0.2233Inherited
Nucleotide cyclase0.2238Inherited
HD-domain/PDEase-like0.26Inherited
Voltage-gated potassium channels0.2825Inherited
PX domain0.315Inherited
RCC1/BLIP-II0.3518Inherited
Protein kinase-like (PK-like)0.354Inherited
PapD-like0.3649Inherited
Regulator of G-protein signaling, RGS0.3731Inherited
HLH, helix-loop-helix DNA-binding domain0.533Inherited
Homeodomain-like0.5394Inherited
SMAD MH1 domain0.556Inherited
PLP-dependent transferases0.5607Inherited
LDL receptor-like module0.6013Inherited
Troponin coil-coiled subunits0.6928Inherited
SMAD/FHA domain0.9054Inherited
POZ domain0.9618Inherited
P-loop containing nucleoside triphosphate hydrolases0.9618Inherited
alpha/beta-Hydrolases1Inherited
C2 domain (Calcium/lipid-binding domain, CaLB)1Inherited
Glucocorticoid receptor-like (DNA-binding domain)1Inherited

(show details)
Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
46785,144074
  • 46785 - "Winged helix" DNA-binding domain
  • 144074 - E2F-DP heterodimerization region
  • 0Direct
    55973,55973
  • 55973 - S-adenosylmethionine synthetase
  • 55973 - S-adenosylmethionine synthetase
  • 0Direct
    50692,54585
  • 50692 - ADC-like
  • 54585 - Cdc48 domain 2-like
  • 0Direct
    53067,100920
  • 53067 - Actin-like ATPase domain
  • 100920 - Heat shock protein 70kD (HSP70), peptide-binding domain
  • 0Direct
    50729,56112
  • 50729 - PH domain-like
  • 56112 - Protein kinase-like (PK-like)
  • 0Direct
    49493,49493
  • 49493 - HSP40/DnaJ peptide-binding domain
  • 49493 - HSP40/DnaJ peptide-binding domain
  • 0Direct
    49265,48726
  • 49265 - Fibronectin type III
  • 48726 - Immunoglobulin
  • 0Direct
    81383,50978
  • 81383 - F-box domain
  • 50978 - WD40 repeat-like
  • 0Direct
    100920,100934
  • 100920 - Heat shock protein 70kD (HSP70), peptide-binding domain
  • 100934 - Heat shock protein 70kD (HSP70), C-terminal subdomain
  • 0Direct
    57938,49493
  • 57938 - DnaJ/Hsp40 cysteine-rich domain
  • 49493 - HSP40/DnaJ peptide-binding domain
  • 0Direct
    49348,55711
  • 49348 - Clathrin adaptor appendage domain
  • 55711 - Subdomain of clathrin and coatomer appendage domain
  • 0Direct
    54585,52540
  • 54585 - Cdc48 domain 2-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    57850,117839
  • 57850 - RING/U-box
  • 117839 - WWE domain
  • 0Direct
    47895,52540
  • 47895 - Transducin (alpha subunit), insertion domain
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.000000000000002099Direct
    54695,81382
  • 54695 - POZ domain
  • 81382 - Skp1 dimerisation domain-like
  • 0.0000000000002404Direct
    63712,90112
  • 63712 - Nicotinic receptor ligand binding domain-like
  • 90112 - Neurotransmitter-gated ion-channel transmembrane pore
  • 0.00001053Direct
    52490,55307
  • 52490 - Tubulin nucleotide-binding domain-like
  • 55307 - Tubulin C-terminal domain-like
  • 0.00001125Direct
    46966,46966
  • 46966 - Spectrin repeat
  • 46966 - Spectrin repeat
  • 0.00003899Direct
    56112,55073
  • 56112 - Protein kinase-like (PK-like)
  • 55073 - Nucleotide cyclase
  • 0.0001046Direct
    57850,57845
  • 57850 - RING/U-box
  • 57845 - B-box zinc-binding domain
  • 0.0001409Direct
    57889,57889
  • 57889 - Cysteine-rich domain
  • 57889 - Cysteine-rich domain
  • 0.0008504Direct
    47473,47473
  • 47473 - EF-hand
  • 47473 - EF-hand
  • 0.001547Inherited
    48403,48403
  • 48403 - Ankyrin repeat
  • 48403 - Ankyrin repeat
  • 0.007214Inherited
    50044,55550
  • 50044 - SH3-domain
  • 55550 - SH2 domain
  • 0.01055Inherited
    48726,48726
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 0.03887Inherited
    48726,49265
  • 48726 - Immunoglobulin
  • 49265 - Fibronectin type III
  • 0.05397Inherited
    47031,50729
  • 47031 - Second domain of FERM
  • 50729 - PH domain-like
  • 0.05884Inherited
    48452,48452
  • 48452 - TPR-like
  • 48452 - TPR-like
  • 0.08715Inherited
    57716,57716
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 0.1129Inherited
    64593,74853
  • 64593 - Intermediate filament protein, coiled coil region
  • 74853 - Lamin A/C globular tail domain
  • 0.26Inherited
    50978,50978
  • 50978 - WD40 repeat-like
  • 50978 - WD40 repeat-like
  • 0.26Inherited
    57424,57424
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 0.556Inherited

    (show details)
    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    57938,49493,49493
  • 57938 - DnaJ/Hsp40 cysteine-rich domain
  • 49493 - HSP40/DnaJ peptide-binding domain
  • 49493 - HSP40/DnaJ peptide-binding domain
  • 0Direct
    46966,46966,46966
  • 46966 - Spectrin repeat
  • 46966 - Spectrin repeat
  • 46966 - Spectrin repeat
  • 0Direct
    55973,55973,55973
  • 55973 - S-adenosylmethionine synthetase
  • 55973 - S-adenosylmethionine synthetase
  • 55973 - S-adenosylmethionine synthetase
  • 0Direct
    50692,54585,52540
  • 50692 - ADC-like
  • 54585 - Cdc48 domain 2-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    57362,57362,57362
  • 57362 - BPTI-like
  • 57362 - BPTI-like
  • 57362 - BPTI-like
  • 0Direct
    54585,52540,52540
  • 54585 - Cdc48 domain 2-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    53067,53067,100920
  • 53067 - Actin-like ATPase domain
  • 53067 - Actin-like ATPase domain
  • 100920 - Heat shock protein 70kD (HSP70), peptide-binding domain
  • 0Direct
    48726,49265,48726
  • 48726 - Immunoglobulin
  • 49265 - Fibronectin type III
  • 48726 - Immunoglobulin
  • 0Direct
    53067,100920,100934
  • 53067 - Actin-like ATPase domain
  • 100920 - Heat shock protein 70kD (HSP70), peptide-binding domain
  • 100934 - Heat shock protein 70kD (HSP70), C-terminal subdomain
  • 0Direct
    57196,57196,57196
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.000003553Direct
    57716,57716,57716
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 0.00005803Direct
    48726,48726,48726
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 0.01475Inherited
    54236,47031,50729
  • 54236 - Ubiquitin-like
  • 47031 - Second domain of FERM
  • 50729 - PH domain-like
  • 0.1285Inherited
    48726,48726,49265
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 49265 - Fibronectin type III
  • 0.1399Inherited
    57424,57424,57424
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 0.556Inherited


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
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