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Worm Phenotype (WP): drug resistant

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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Root: WP Hierarchy (worm phenotype from Wormbase Release WS226)

Shortest distance to current term (+ for parents, - for children) WP term [WP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + + + + + 7:   Variant [WBPhenotype:0000886] <4>
+ + + + + + 6:   physiology variant [WBPhenotype:0000519] <7>(487|558) (487|240|64)
+ + + + + 5:   organism physiology variant [WBPhenotype:0000576] <10>(355|415) (355|191|56)
+ + + + 4:   organism homeostasis metabolism variant [WBPhenotype:0000577] <17>(346|406) (348|189|55)
+ + + 3:   organism environmental stimulus response variant [WBPhenotype:0000738] <16>(115|103) (118|51|16)
+ + 2:   chemical response variant [WBPhenotype:0000523] <11>(65|58) (66|25|6)
+ 1:   drug response variant [WBPhenotype:0000631] <27>(41|37) (42|16|2)
0:   drug resistant [WBPhenotype:0000011] <21>(16|17) (18|6|1)
- 1:   serotonin resistant [WBPhenotype:0000024] <5>(2|2) (3|0|0)
- 1:   anesthetic resistant [WBPhenotype:0000009] <3>(1|1) (1|0|0)
- 1:   biogenic amine receptor antagonist resistant [WBPhenotype:0001601] <3>(0|1) (0|0|0)
- 1:   cholinergic agonist resistant [WBPhenotype:0001578] <3>(2|2) (2|1|0)
- 1:   Fluorouracil resistant [WBPhenotype:0001649] <2>(1|1) (1|0|0)
- 1:   acetylcholinesterase inhibitor resistant [WBPhenotype:0001289] <2>(3|6) (4|1|0)
- 1:   anticonvulsant resistant [WBPhenotype:0001615] <2>(0|0) (0|0|0)
- 1:   imipramine resistant [WBPhenotype:0000340] <1>(2|1) (2|0|0)
- 1:   inhibitors of na k atpase resistant [WBPhenotype:0000331] <1>(0|0) (0|0|0)
- 1:   serotonin reuptake inhibitor resistant [WBPhenotype:0000381] <1>(0|0) (0|0|0)
- 1:   Bacillus thuringiensis toxin resistant [WBPhenotype:0001507](0|0) (0|0|0)
- 1:   alpha amanitin resistant [WBPhenotype:0000089](0|0) (0|0|0)
- 1:   caffeine resistant [WBPhenotype:0000252](0|0) (0|0|0)
- 1:   calcium channel modulator resistant [WBPhenotype:0000560](0|0) (0|0|0)
- 1:   chloroquinone resistant [WBPhenotype:0000489](0|0) (0|0|0)
- 1:   colchicine resistant [WBPhenotype:0000487](1|1) (1|0|0)
- 1:   dopamine resistant [WBPhenotype:0002077](0|0) (0|0|0)
- 1:   ivermectin resistant [WBPhenotype:0002053](1|1) (1|2|0)
- 1:   muscimol resistant [WBPhenotype:0001204](0|0) (0|0|0)
- 1:   phorbol ester resistant [WBPhenotype:0001839](0|1) (0|0|0)
- 1:   pore forming toxin resistant [WBPhenotype:0002060](0|0) (0|0|0)


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Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
cAMP-binding domain-like0.0003388Direct
Myosin rod fragments0.0006293Direct
PRTase-like0.0006293Direct
C2 domain (Calcium/lipid-binding domain, CaLB)0.0006838Direct
SNARE-like0.003852Inherited
Bromodomain0.004983Inherited
TPR-like0.01373Inherited
Spectrin repeat0.07346Inherited
Voltage-gated potassium channels0.1119Inherited
ENTH/VHS domain0.131Inherited
beta-beta-alpha zinc fingers0.2231Inherited
Protein kinase-like (PK-like)0.4381Inherited
Homeodomain-like0.6904Inherited
Nicotinic receptor ligand binding domain-like1Inherited
Neurotransmitter-gated ion-channel transmembrane pore1Inherited
Family A G protein-coupled receptor-like1Inherited


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Family

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SCOP termFDR (all)Annotation (direct or inherited)
Synaptotagmin-like (S variant)0.000008783Direct
Protein kinase cysteine-rich domain (cys2, phorbol-binding domain)0.00009688Direct
Clathrin coat assembly domain0.0003217Direct
Phosphoribosyltransferases (PRTases)0.0003217Direct
cAMP-binding domain0.0004415Direct
Bromodomain0.008031Inherited
FYVE, a phosphatidylinositol-3-phosphate binding domain0.008031Inherited
Rhodopsin-like0.01203Inherited
PLC-like (P variant)0.06456Inherited
Spectrin repeat0.06456Inherited
I set domains0.07517Inherited
WD40-repeat0.08867Inherited
Voltage-gated potassium channels0.1131Inherited
Pleckstrin-homology domain (PH domain)0.148Inherited
Protein kinases, catalytic subunit0.2718Inherited
Neurotransmitter-gated ion-channel transmembrane pore1Inherited
Nicotinic receptor ligand binding domain-like1Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
cAMP-binding domain-like0.000281Direct
PRTase-like0.0005248Direct
Myosin rod fragments0.0005248Direct
C2 domain (Calcium/lipid-binding domain, CaLB)0.000571Direct
PDZ domain-like0.0008926Direct
SNARE-like0.003273Inherited
Bromodomain0.004243Inherited
TPR-like0.01187Inherited
Spectrin repeat0.06579Inherited
Voltage-gated potassium channels0.1013Inherited
ENTH/VHS domain0.1192Inherited
WW domain0.1192Inherited
beta-beta-alpha zinc fingers0.2064Inherited
Protein kinase-like (PK-like)0.4168Inherited
Homeodomain-like0.6696Inherited
Neurotransmitter-gated ion-channel transmembrane pore1Inherited
Family A G protein-coupled receptor-like1Inherited
Nicotinic receptor ligand binding domain-like1Inherited

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Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
57889,57889
  • 57889 - Cysteine-rich domain
  • 57889 - Cysteine-rich domain
  • 0.00002243Direct
    49562,49562
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 0.0001892Direct
    50978,50978
  • 50978 - WD40 repeat-like
  • 50978 - WD40 repeat-like
  • 0.0001892Direct
    48452,48452
  • 48452 - TPR-like
  • 48452 - TPR-like
  • 0.0459Inherited
    48726,49265
  • 48726 - Immunoglobulin
  • 49265 - Fibronectin type III
  • 0.1977Inherited
    63712,90112
  • 63712 - Nicotinic receptor ligand binding domain-like
  • 90112 - Neurotransmitter-gated ion-channel transmembrane pore
  • 1Inherited

    (show details)
    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    46966,46966,46966
  • 46966 - Spectrin repeat
  • 46966 - Spectrin repeat
  • 46966 - Spectrin repeat
  • 0.00007359Direct


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
    Plot tree as:   Download Newick format tree:
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