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Worm Phenotype (WP): protein expression variant

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Root: WP Hierarchy (worm phenotype from Wormbase Release WS226)

Shortest distance to current term (+ for parents, - for children) WP term [WP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + + + + 6:   Variant [WBPhenotype:0000886] <2>
+ + + + + 5:   physiology variant [WBPhenotype:0000519] <14>(510|587) (510|248|68)
+ + + + 4:   organism physiology variant [WBPhenotype:0000576] <9>(369|431) (372|193|56)
+ + + 3:   organism homeostasis metabolism variant [WBPhenotype:0000577] <16>(361|421) (363|190|55)
+ + 2:   organism metabolism processing variant [WBPhenotype:0000027] <25>(178|190) (182|87|26)
+ 1:   gene expression variant [WBPhenotype:0000717] <11>(127|139) (131|64|20)
0:   protein expression variant [WBPhenotype:0000112] <6>(39|44) (41|19|6)
- 1:   protein modification variant [WBPhenotype:0001382] <9>(13|10) (13|3|0)
- 1:   antibody staining variant [WBPhenotype:0000424] <6>(5|5) (5|2|1)
- 1:   translation variant [WBPhenotype:0000121] <4>(0|0) (0|0|0)
- 1:   level of protein expression variant [WBPhenotype:0001400] <2>(11|12) (11|9|4)
- 1:   pattern protein expression variant [WBPhenotype:0001408] <2>(12|19) (12|6|2)
- 1:   electrophoretic variant protein [WBPhenotype:0000394](0|0) (0|0|0)


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Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
Heme-dependent catalase-like0Direct
14-3-3 protein0Direct
Protein kinase-like (PK-like)0.0000000002272Direct
Arginase/deacetylase0.0000000008383Direct
ARM repeat0.000000001134Direct
SH3-domain0.000000006948Direct
C2 domain (Calcium/lipid-binding domain, CaLB)0.00000003429Direct
Intermediate filament protein, coiled coil region0.000001194Direct
PH domain-like0.000001283Direct
SH2 domain0.00001267Direct
Lamin A/C globular tail domain0.0000245Direct
GTPase activation domain, GAP0.00005953Direct
Integrin domains0.0001582Direct
PX domain0.0003161Direct
Cullin homology domain0.0003161Direct
PDZ domain-like0.0006695Direct
ARID-like0.0006893Direct
CAD & PB1 domains0.0006893Direct
DHS-like NAD/FAD-binding domain0.001101Inherited
Cullin repeat-like0.001763Inherited
Sm-like ribonucleoproteins0.001994Inherited
SET domain0.002544Inherited
Second domain of FERM0.005064Inherited
Cysteine-rich domain0.006669Inherited
Frizzled cysteine-rich domain0.01264Inherited
Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor0.01552Inherited
Spectrin repeat0.01552Inherited
Activating enzymes of the ubiquitin-like proteins0.01552Inherited
Cyclin-like0.01683Inherited
Riboflavin synthase domain-like0.09398Inherited
Ferredoxin reductase-like, C-terminal NADP-linked domain0.09398Inherited
Transducin (alpha subunit), insertion domain0.1379Inherited
Actin-like ATPase domain0.1898Inherited
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases0.2377Inherited
Clavaminate synthase-like0.2541Inherited
"Winged helix" DNA-binding domain0.4065Inherited
FYVE/PHD zinc finger0.5645Inherited
Translation proteins0.8941Inherited
Chromo domain-like0.9264Inherited


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Family

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SCOP termFDR (all)Annotation (direct or inherited)
Sir2 family of transcriptional regulators0Direct
Inositol polyphosphate 5-phosphatase (IPP5)0Direct
Heme-dependent catalases0Direct
Cullin repeat0Direct
SCF ubiquitin ligase complex WHB domain0Direct
Phoshoinositide 3-kinase (PI3K), catalytic domain0Direct
14-3-3 protein0Direct
Phoshoinositide 3-kinase (PI3K) helical domain0Direct
Histone deacetylase, HDAC0Direct
Integrin domains0Direct
Phosphatidylinositol phosphate kinase IIbeta, PIPK IIbeta0Direct
SH3-domain0.00000002685Direct
Protein kinases, catalytic subunit0.000001587Direct
Intermediate filament protein, coiled coil region0.000003948Direct
PLC-like (P variant)0.00002509Direct
EF-hand modules in multidomain proteins0.00002804Direct
PDZ domain0.0001062Direct
SH2 domain0.0001316Direct
Lamin A/C globular tail domain0.000175Direct
Pleckstrin-homology domain (PH domain)0.0001776Direct
PX domain0.0002994Direct
Cullin homology domain0.0002994Direct
Mammalian PLC0.001022Inherited
LIM domain0.001022Inherited
Histone lysine methyltransferases0.001891Inherited
First domain of FERM0.002924Inherited
Third domain of FERM0.003798Inherited
Spectrin repeat0.003798Inherited
Pumilio repeat0.005054Inherited
Sm motif of small nuclear ribonucleoproteins, SNRNP0.005435Inherited
Second domain of FERM0.007478Inherited
Synaptotagmin-like (S variant)0.007478Inherited
Protein kinase cysteine-rich domain (cys2, phorbol-binding domain)0.007891Inherited
Frizzled cysteine-rich domain0.01159Inherited
G proteins0.01289Inherited
Armadillo repeat0.01304Inherited
Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor0.0147Inherited
Extended AAA-ATPase domain0.097Inherited
Actin/HSP700.097Inherited
Transducin (alpha subunit), insertion domain0.1374Inherited
Clathrin coat assembly domain0.156Inherited
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases0.156Inherited
Elongation factors0.4859Inherited
PHD domain0.5065Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
Heme-dependent catalase-like0Direct
14-3-3 protein0Direct
Protein kinase-like (PK-like)0.00000000018Direct
Arginase/deacetylase0.0000000006655Direct
ARM repeat0.0000000009002Direct
SH3-domain0.000000005538Direct
C2 domain (Calcium/lipid-binding domain, CaLB)0.00000002742Direct
Intermediate filament protein, coiled coil region0.0000009654Direct
PH domain-like0.000001037Direct
SH2 domain0.00001031Direct
Lamin A/C globular tail domain0.00001999Direct
GTPase activation domain, GAP0.00004872Direct
Integrin domains0.0001299Direct
Cullin homology domain0.0002604Direct
PX domain0.0002604Direct
PDZ domain-like0.0005552Direct
CAD & PB1 domains0.0005718Direct
ARID-like0.0005718Direct
DNase I-like0.0009173Direct
DHS-like NAD/FAD-binding domain0.0009173Direct
PLC-like phosphodiesterases0.0009173Direct
Cullin repeat-like0.001476Inherited
Sm-like ribonucleoproteins0.001672Inherited
SET domain0.002143Inherited
Second domain of FERM0.004304Inherited
Cysteine-rich domain0.005687Inherited
Frizzled cysteine-rich domain0.01091Inherited
Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor0.01345Inherited
Activating enzymes of the ubiquitin-like proteins0.01345Inherited
Spectrin repeat0.01345Inherited
Cyclin-like0.01461Inherited
Ferredoxin reductase-like, C-terminal NADP-linked domain0.08471Inherited
Riboflavin synthase domain-like0.08471Inherited
Transducin (alpha subunit), insertion domain0.1256Inherited
Actin-like ATPase domain0.1745Inherited
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases0.2202Inherited
Clavaminate synthase-like0.2363Inherited
"Winged helix" DNA-binding domain0.3857Inherited
FYVE/PHD zinc finger0.5428Inherited
Translation proteins0.8787Inherited
Chromo domain-like0.9122Inherited

(show details)
Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
49562,48371
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 48371 - ARM repeat
  • 0Direct
    74788,75632
  • 74788 - Cullin repeat-like
  • 75632 - Cullin homology domain
  • 0Direct
    75632,46785
  • 75632 - Cullin homology domain
  • 46785 - "Winged helix" DNA-binding domain
  • 0Direct
    64593,74853
  • 64593 - Intermediate filament protein, coiled coil region
  • 74853 - Lamin A/C globular tail domain
  • 0.0000065Direct
    48371,56112
  • 48371 - ARM repeat
  • 56112 - Protein kinase-like (PK-like)
  • 0.0000117Direct
    57716,57716
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 0.00007523Direct
    55550,50044
  • 55550 - SH2 domain
  • 50044 - SH3-domain
  • 0.0001299Direct
    47031,50729
  • 47031 - Second domain of FERM
  • 50729 - PH domain-like
  • 0.0008731Direct
    50044,50044
  • 50044 - SH3-domain
  • 50044 - SH3-domain
  • 0.003194Inherited
    50044,55550
  • 50044 - SH3-domain
  • 55550 - SH2 domain
  • 0.003194Inherited
    54236,47031
  • 54236 - Ubiquitin-like
  • 47031 - Second domain of FERM
  • 0.006564Inherited
    46966,46966
  • 46966 - Spectrin repeat
  • 46966 - Spectrin repeat
  • 0.01091Inherited
    64356,49447
  • 64356 - SNARE-like
  • 49447 - Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor
  • 0.01091Inherited
    57196,57196
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.0184Inherited
    57889,57889
  • 57889 - Cysteine-rich domain
  • 57889 - Cysteine-rich domain
  • 0.03408Inherited
    47954,47954
  • 47954 - Cyclin-like
  • 47954 - Cyclin-like
  • 0.04042Inherited
    47895,52540
  • 47895 - Transducin (alpha subunit), insertion domain
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.1256Inherited
    53067,53067
  • 53067 - Actin-like ATPase domain
  • 53067 - Actin-like ATPase domain
  • 0.1745Inherited
    52540,50447
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 50447 - Translation proteins
  • 0.4636Inherited

    (show details)
    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    49562,48371,56112
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 48371 - ARM repeat
  • 56112 - Protein kinase-like (PK-like)
  • 0Direct
    74788,75632,46785
  • 74788 - Cullin repeat-like
  • 75632 - Cullin homology domain
  • 46785 - "Winged helix" DNA-binding domain
  • 0Direct
    57716,57716,57716
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 0.0002604Direct
    54236,47031,50729
  • 54236 - Ubiquitin-like
  • 47031 - Second domain of FERM
  • 50729 - PH domain-like
  • 0.004447Inherited
    46966,46966,46966
  • 46966 - Spectrin repeat
  • 46966 - Spectrin repeat
  • 46966 - Spectrin repeat
  • 0.01091Inherited
    57424,57424,57424
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 0.02021Inherited


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
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