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Worm Phenotype (WP): protein expression variant

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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Root: WP Hierarchy (worm phenotype from Wormbase Release WS226)

Shortest distance to current term (+ for parents, - for children) WP term [WP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + + + + 6:   Variant [WBPhenotype:0000886] <4>
+ + + + + 5:   physiology variant [WBPhenotype:0000519] <7>(487|558) (487|240|64)
+ + + + 4:   organism physiology variant [WBPhenotype:0000576] <10>(355|415) (355|191|56)
+ + + 3:   organism homeostasis metabolism variant [WBPhenotype:0000577] <17>(346|406) (348|189|55)
+ + 2:   organism metabolism processing variant [WBPhenotype:0000027] <25>(171|182) (175|80|24)
+ 1:   gene expression variant [WBPhenotype:0000717] <10>(122|134) (127|61|19)
0:   protein expression variant [WBPhenotype:0000112] <6>(38|44) (39|19|6)
- 1:   protein modification variant [WBPhenotype:0001382] <9>(11|9) (11|3|0)
- 1:   antibody staining variant [WBPhenotype:0000424] <6>(5|5) (5|2|1)
- 1:   translation variant [WBPhenotype:0000121] <4>(0|0) (0|0|0)
- 1:   level of protein expression variant [WBPhenotype:0001400] <2>(11|12) (11|9|4)
- 1:   pattern protein expression variant [WBPhenotype:0001408] <2>(12|19) (12|6|2)
- 1:   electrophoretic variant protein [WBPhenotype:0000394](0|0) (0|0|0)


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
Heme-dependent catalase-like0Direct
14-3-3 protein0Direct
Protein kinase-like (PK-like)0.0000000004981Direct
Arginase/deacetylase0.0000000007765Direct
ARM repeat0.000000007512Direct
SH3-domain0.0000000159Direct
C2 domain (Calcium/lipid-binding domain, CaLB)0.00000002995Direct
Intermediate filament protein, coiled coil region0.000001118Direct
SET domain0.000001386Direct
PH domain-like0.000003619Direct
SH2 domain0.00001133Direct
Lamin A/C globular tail domain0.00002323Direct
GTPase activation domain, GAP0.00005511Direct
Integrin domains0.0001532Direct
Cullin homology domain0.0004111Direct
PX domain0.0004111Direct
CAD & PB1 domains0.0006672Direct
ARID-like0.0006672Direct
DHS-like NAD/FAD-binding domain0.001371Inherited
Cullin repeat-like0.002254Inherited
Sm-like ribonucleoproteins0.002688Inherited
Second domain of FERM0.004851Inherited
Cysteine-rich domain0.005738Inherited
Cyclin-like0.0122Inherited
Frizzled cysteine-rich domain0.01455Inherited
Activating enzymes of the ubiquitin-like proteins0.01833Inherited
Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor0.01833Inherited
Spectrin repeat0.01833Inherited
FYVE/PHD zinc finger0.09209Inherited
Riboflavin synthase domain-like0.1055Inherited
Ferredoxin reductase-like, C-terminal NADP-linked domain0.1055Inherited
Chromo domain-like0.1443Inherited
Transducin (alpha subunit), insertion domain0.1585Inherited
Actin-like ATPase domain0.2262Inherited
"Winged helix" DNA-binding domain0.2425Inherited
Clavaminate synthase-like0.2489Inherited
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases0.2607Inherited
Translation proteins0.9165Inherited


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Family

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SCOP termFDR (all)Annotation (direct or inherited)
Phosphatidylinositol phosphate kinase IIbeta, PIPK IIbeta0Direct
Phoshoinositide 3-kinase (PI3K), catalytic domain0Direct
Inositol polyphosphate 5-phosphatase (IPP5)0Direct
Phoshoinositide 3-kinase (PI3K) helical domain0Direct
Integrin domains0Direct
Histone deacetylase, HDAC0Direct
Cullin repeat0Direct
SCF ubiquitin ligase complex WHB domain0Direct
Sir2 family of transcriptional regulators0Direct
Heme-dependent catalases0Direct
14-3-3 protein0Direct
SH3-domain0.00000002398Direct
Protein kinases, catalytic subunit0.000001268Direct
Intermediate filament protein, coiled coil region0.000003781Direct
EF-hand modules in multidomain proteins0.00002734Direct
PLC-like (P variant)0.00003361Direct
SH2 domain0.0001223Direct
PDZ domain0.0001571Direct
Lamin A/C globular tail domain0.0001698Direct
Pleckstrin-homology domain (PH domain)0.0002758Direct
Histone lysine methyltransferases0.0003259Direct
PX domain0.0003748Direct
Cullin homology domain0.0003748Direct
Mammalian PLC0.001241Inherited
LIM domain0.001241Inherited
First domain of FERM0.002871Inherited
Third domain of FERM0.003717Inherited
Spectrin repeat0.004077Inherited
Protein kinase cysteine-rich domain (cys2, phorbol-binding domain)0.005334Inherited
Sm motif of small nuclear ribonucleoproteins, SNRNP0.006654Inherited
Second domain of FERM0.007308Inherited
Synaptotagmin-like (S variant)0.007308Inherited
Frizzled cysteine-rich domain0.01319Inherited
Armadillo repeat0.01581Inherited
Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor0.01703Inherited
G proteins0.02071Inherited
Pumilio repeat0.04251Inherited
PHD domain0.1063Inherited
Actin/HSP700.1164Inherited
Extended AAA-ATPase domain0.1164Inherited
Transducin (alpha subunit), insertion domain0.156Inherited
Clathrin coat assembly domain0.1713Inherited
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases0.1713Inherited
Elongation factors0.5155Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
14-3-3 protein0Direct
Heme-dependent catalase-like0Direct
Protein kinase-like (PK-like)0.0000000003977Direct
Arginase/deacetylase0.0000000006206Direct
ARM repeat0.000000006028Direct
SH3-domain0.00000001277Direct
C2 domain (Calcium/lipid-binding domain, CaLB)0.00000002411Direct
Intermediate filament protein, coiled coil region0.0000009102Direct
SET domain0.00000113Direct
PH domain-like0.000002959Direct
SH2 domain0.000009276Direct
Lamin A/C globular tail domain0.00001906Direct
GTPase activation domain, GAP0.00004541Direct
Integrin domains0.0001265Direct
Cullin homology domain0.0003415Direct
PX domain0.0003415Direct
CAD & PB1 domains0.0005568Direct
ARID-like0.0005568Direct
PDZ domain-like0.0008985Direct
DHS-like NAD/FAD-binding domain0.001151Inherited
Cullin repeat-like0.001904Inherited
Sm-like ribonucleoproteins0.002273Inherited
Second domain of FERM0.00413Inherited
Cysteine-rich domain0.004894Inherited
Cyclin-like0.01052Inherited
Frizzled cysteine-rich domain0.01258Inherited
Spectrin repeat0.01592Inherited
Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor0.01592Inherited
Activating enzymes of the ubiquitin-like proteins0.01592Inherited
FYVE/PHD zinc finger0.08293Inherited
Riboflavin synthase domain-like0.09543Inherited
Ferredoxin reductase-like, C-terminal NADP-linked domain0.09543Inherited
Chromo domain-like0.1318Inherited
Transducin (alpha subunit), insertion domain0.1452Inherited
Actin-like ATPase domain0.2094Inherited
"Winged helix" DNA-binding domain0.2249Inherited
Clavaminate synthase-like0.2312Inherited
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases0.2427Inherited
Translation proteins0.9018Inherited

(show details)
Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
75632,46785
  • 75632 - Cullin homology domain
  • 46785 - "Winged helix" DNA-binding domain
  • 0Direct
    49562,48371
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 48371 - ARM repeat
  • 0Direct
    74788,75632
  • 74788 - Cullin repeat-like
  • 75632 - Cullin homology domain
  • 0Direct
    64593,74853
  • 64593 - Intermediate filament protein, coiled coil region
  • 74853 - Lamin A/C globular tail domain
  • 0.000006228Direct
    48371,56112
  • 48371 - ARM repeat
  • 56112 - Protein kinase-like (PK-like)
  • 0.0000113Direct
    57716,57716
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 0.0001151Direct
    55550,50044
  • 55550 - SH2 domain
  • 50044 - SH3-domain
  • 0.0001265Direct
    47031,50729
  • 47031 - Second domain of FERM
  • 50729 - PH domain-like
  • 0.0008399Direct
    50044,55550
  • 50044 - SH3-domain
  • 55550 - SH2 domain
  • 0.003836Inherited
    50044,50044
  • 50044 - SH3-domain
  • 50044 - SH3-domain
  • 0.003836Inherited
    54236,47031
  • 54236 - Ubiquitin-like
  • 47031 - Second domain of FERM
  • 0.006333Inherited
    64356,49447
  • 64356 - SNARE-like
  • 49447 - Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor
  • 0.01258Inherited
    46966,46966
  • 46966 - Spectrin repeat
  • 46966 - Spectrin repeat
  • 0.01258Inherited
    57196,57196
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.02317Inherited
    47954,47954
  • 47954 - Cyclin-like
  • 47954 - Cyclin-like
  • 0.02823Inherited
    57889,57889
  • 57889 - Cysteine-rich domain
  • 57889 - Cysteine-rich domain
  • 0.03977Inherited
    47895,52540
  • 47895 - Transducin (alpha subunit), insertion domain
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.1452Inherited
    53067,53067
  • 53067 - Actin-like ATPase domain
  • 53067 - Actin-like ATPase domain
  • 0.2094Inherited
    52540,50447
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 50447 - Translation proteins
  • 0.4958Inherited

    (show details)
    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    49562,48371,56112
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 48371 - ARM repeat
  • 56112 - Protein kinase-like (PK-like)
  • 0Direct
    74788,75632,46785
  • 74788 - Cullin repeat-like
  • 75632 - Cullin homology domain
  • 46785 - "Winged helix" DNA-binding domain
  • 0Direct
    57716,57716,57716
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 0.0003415Direct
    54236,47031,50729
  • 54236 - Ubiquitin-like
  • 47031 - Second domain of FERM
  • 50729 - PH domain-like
  • 0.004292Inherited
    46966,46966,46966
  • 46966 - Spectrin repeat
  • 46966 - Spectrin repeat
  • 46966 - Spectrin repeat
  • 0.01258Inherited
    57424,57424,57424
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 0.01957Inherited


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
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