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Worm Phenotype (WP): protein expression reduced

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Root: WP Hierarchy (worm phenotype from Wormbase Release WS226)

Shortest distance to current term (+ for parents, - for children) WP term [WP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + + + + + + 8:   Variant [WBPhenotype:0000886] <4>
+ + + + + + + 7:   physiology variant [WBPhenotype:0000519] <7>(487|558) (487|240|64)
+ + + + + + 6:   organism physiology variant [WBPhenotype:0000576] <10>(355|415) (355|191|56)
+ + + + + 5:   organism homeostasis metabolism variant [WBPhenotype:0000577] <17>(346|406) (348|189|55)
+ + + + 4:   organism metabolism processing variant [WBPhenotype:0000027] <25>(171|182) (175|80|24)
+ + + 3:   gene expression variant [WBPhenotype:0000717] <10>(122|134) (127|61|19)
+ + 2:   protein expression variant [WBPhenotype:0000112] <6>(38|44) (39|19|6)
+ 1:   level of protein expression variant [WBPhenotype:0001400] <2>(11|12) (11|9|4)
0:   protein expression reduced [WBPhenotype:0000120] <5>(7|9) (7|8|3)
- 1:   enzyme expression level reduced [WBPhenotype:0000123] <1>(0|0) (0|0|0)
- 1:   protein expression absent [WBPhenotype:0001410](0|0) (0|0|0)
- 1:   protein expression reduced cell specific [WBPhenotype:0001407](0|0) (0|0|0)
- 1:   protein expression reduced hermaphrodite [WBPhenotype:0001311](0|0) (0|0|0)
- 1:   protein expression reduced male [WBPhenotype:0001406](0|0) (0|0|0)


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
SH3-domain0.00000000001449Direct
SH2 domain0.0000000004995Direct
Integrin domains0.000001843Direct
Second domain of FERM0.00001228Direct
Actin-like ATPase domain0.0001614Direct
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases0.0004426Direct
PX domain0.0006388Direct


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Family

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SCOP termFDR (all)Annotation (direct or inherited)
Integrin domains0Direct
SH3-domain0.0000000003913Direct
SH2 domain0.00000001015Direct
LIM domain0.0000008165Direct
Second domain of FERM0.00002445Direct
Third domain of FERM0.00002597Direct
Actin/HSP700.00002914Direct
First domain of FERM0.00004826Direct
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases0.0005594Direct


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
SH3-domain0.00000000001153Direct
SH2 domain0.0000000003989Direct
Integrin domains0.000001504Direct
Second domain of FERM0.00001006Direct
Actin-like ATPase domain0.0001333Direct
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases0.0003677Direct
PX domain0.0005329Direct

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Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
57716,57716
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 0.000000001644Direct
    55550,50044
  • 55550 - SH2 domain
  • 50044 - SH3-domain
  • 0.000001504Direct
    47031,50729
  • 47031 - Second domain of FERM
  • 50729 - PH domain-like
  • 0.000001588Direct
    57196,57196
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.00002561Direct
    54236,47031
  • 54236 - Ubiquitin-like
  • 47031 - Second domain of FERM
  • 0.00004049Direct
    50044,55550
  • 50044 - SH3-domain
  • 55550 - SH2 domain
  • 0.00004575Direct
    50044,50044
  • 50044 - SH3-domain
  • 50044 - SH3-domain
  • 0.00004575Direct
    53067,53067
  • 53067 - Actin-like ATPase domain
  • 53067 - Actin-like ATPase domain
  • 0.0000505Direct

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    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    57716,57716,57716
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 0.000000001079Direct
    54236,47031,50729
  • 54236 - Ubiquitin-like
  • 47031 - Second domain of FERM
  • 50729 - PH domain-like
  • 0.00002579Direct
    57424,57424,57424
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 0.0003677Direct


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
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