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Worm Phenotype (WP): cell stress response variant

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Root: WP Hierarchy (worm phenotype from Wormbase Release WS226)

Shortest distance to current term (+ for parents, - for children) WP term [WP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + + 4:   Variant [WBPhenotype:0000886] <4>
+ + + 3:   physiology variant [WBPhenotype:0000519] <7>(487|558) (487|240|64)
+ + 2:   blast cell physiology variant [WBPhenotype:0000985] <26>(152|154) (153|66|17)
+ + 2:   cell physiology variant [WBPhenotype:0000536] <26>(152|154) (153|66|17)
+ 1:   cell homeostasis metabolism variant [WBPhenotype:0000585] <12>(65|61) (65|26|11)
0:   cell stress response variant [WBPhenotype:0000142] <12>(28|24) (28|9|3)
- 1:   cell ionizing radiation response variant [WBPhenotype:0001324] <5>(8|3) (8|0|0)
- 1:   DNA damage response variant [WBPhenotype:0000739] <4>(0|0) (0|0|0)
- 1:   cell UV response variant [WBPhenotype:0000100] <4>(0|0) (0|0|0)
- 1:   DNA damage checkpoint variant [WBPhenotype:0000741] <3>(0|0) (0|0|0)
- 1:   oxidative stress response variant [WBPhenotype:0000068] <3>(7|7) (7|2|0)
- 1:   osmotic stress response variant [WBPhenotype:0001725] <1>(4|3) (4|3|1)
- 1:   ER stress response variant [WBPhenotype:0001485](0|0) (0|0|0)
- 1:   mitochondrial stress response variant [WBPhenotype:0002434](0|0) (0|0|0)
- 1:   pathogen induced cell death increased [WBPhenotype:0000144](0|0) (0|0|0)
- 1:   response to injury variant [WBPhenotype:0001840](4|4) (4|1|0)
- 1:   unfolded protein accumulation [WBPhenotype:0001486](0|0) (0|0|0)
- 1:   unfolded protein response variant [WBPhenotype:0001719](6|5) (6|4|2)


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Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
RBP11-like subunits of RNA polymerase0Direct
Lipovitellin-phosvitin complex; beta-sheet shell regions0.00000001679Direct
Lipovitellin-phosvitin complex, superhelical domain0.00000001679Direct
beta and beta-prime subunits of DNA dependent RNA-polymerase0.00000001679Direct
PLC-like phosphodiesterases0.0000008925Direct
GroEL equatorial domain-like0.000001195Direct
GroEL-intermediate domain like0.000001195Direct
GroEL apical domain-like0.000002835Direct
RING/U-box0.000006966Direct
5' to 3' exonuclease, C-terminal subdomain0.000009195Direct
PIN domain-like0.0000185Direct
FAD/NAD-linked reductases, dimerisation (C-terminal) domain0.0001198Direct
Sm-like ribonucleoproteins0.001671Inherited
C2 domain (Calcium/lipid-binding domain, CaLB)0.003037Inherited
Saposin0.03686Inherited
Thioredoxin-like0.04325Inherited
PLP-dependent transferases0.05487Inherited
S-adenosyl-L-methionine-dependent methyltransferases0.09264Inherited
Lipocalins0.123Inherited
EF-hand0.1933Inherited
Cysteine proteinases0.1933Inherited
Cysteine-rich domain0.2352Inherited
Nucleotidylyl transferase0.2352Inherited
PH domain-like0.2859Inherited
E set domains0.3595Inherited
Metallo-dependent phosphatases0.4814Inherited
Nucleic acid-binding proteins0.758Inherited
"Winged helix" DNA-binding domain0.8992Inherited


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Family

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SCOP termFDR (all)Annotation (direct or inherited)
Arginine methyltransferase0Direct
RNA-polymerase beta0Direct
Mammalian PLC0Direct
Lipovitellin-phosvitin complex, superhelical domain0.00000003303Direct
Lipovitellin-phosvitin complex; beta-sheet shell regions0.00000003303Direct
Ubiquitin carboxyl-terminal hydrolase UCH-L0.00001316Direct
Group II chaperonin (CCT, TRIC), intermediate domain0.00001316Direct
5' to 3' exonuclease, C-terminal subdomain0.00001316Direct
5' to 3' exonuclease catalytic domain0.00001316Direct
Group II chaperonin (CCT, TRIC), ATPase domain0.00003078Direct
EF-hand modules in multidomain proteins0.0000611Direct
Erythroid transcription factor GATA-10.00006522Direct
Group II chaperonin (CCT, TRIC), apical domain0.00006522Direct
Tandem AAA-ATPase domain0.0001655Direct
FAD/NAD-linked reductases, dimerisation (C-terminal) domain0.0001709Direct
PLC-like (P variant)0.0002838Direct
Glutathione peroxidase-like0.009771Inherited
FAD/NAD-linked reductases, N-terminal and central domains0.0129Inherited
Pleckstrin-homology domain (PH domain)0.01703Inherited
Glutathione S-transferase (GST), N-terminal domain0.01977Inherited
RING finger domain, C3HC40.03079Inherited
Fatty acid binding protein-like0.1046Inherited
Class I aminoacyl-tRNA synthetases (RS), catalytic domain0.1046Inherited
Protein kinase cysteine-rich domain (cys2, phorbol-binding domain)0.2079Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
RBP11-like subunits of RNA polymerase0Direct
beta and beta-prime subunits of DNA dependent RNA-polymerase0.00000001349Direct
Lipovitellin-phosvitin complex; beta-sheet shell regions0.00000001349Direct
Lipovitellin-phosvitin complex, superhelical domain0.00000001349Direct
PLC-like phosphodiesterases0.000000726Direct
GroEL-intermediate domain like0.0000009734Direct
GroEL equatorial domain-like0.0000009734Direct
GroEL apical domain-like0.000002316Direct
RING/U-box0.000005699Direct
5' to 3' exonuclease, C-terminal subdomain0.000007526Direct
PIN domain-like0.00001518Direct
FAD/NAD-linked reductases, dimerisation (C-terminal) domain0.00009895Direct
Sm-like ribonucleoproteins0.001406Inherited
C2 domain (Calcium/lipid-binding domain, CaLB)0.002571Inherited
Saposin0.03252Inherited
Thioredoxin-like0.03826Inherited
PLP-dependent transferases0.04874Inherited
S-adenosyl-L-methionine-dependent methyltransferases0.08345Inherited
Lipocalins0.1117Inherited
EF-hand0.1778Inherited
Cysteine proteinases0.1778Inherited
Nucleotidylyl transferase0.2179Inherited
Cysteine-rich domain0.2179Inherited
PH domain-like0.2671Inherited
E set domains0.3393Inherited
Metallo-dependent phosphatases0.4596Inherited
Nucleic acid-binding proteins0.7379Inherited
"Winged helix" DNA-binding domain0.8837Inherited

(show details)
Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
47473,51695
  • 47473 - EF-hand
  • 51695 - PLC-like phosphodiesterases
  • 0Direct
    50729,47473
  • 50729 - PH domain-like
  • 47473 - EF-hand
  • 0Direct
    51695,49562
  • 51695 - PLC-like phosphodiesterases
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 0Direct
    56968,48431
  • 56968 - Lipovitellin-phosvitin complex; beta-sheet shell regions
  • 48431 - Lipovitellin-phosvitin complex, superhelical domain
  • 0.00000001349Direct
    48431,56968
  • 48431 - Lipovitellin-phosvitin complex, superhelical domain
  • 56968 - Lipovitellin-phosvitin complex; beta-sheet shell regions
  • 0.00000001349Direct
    54849,52029
  • 54849 - GroEL-intermediate domain like
  • 52029 - GroEL apical domain-like
  • 0.0000009734Direct
    48592,54849
  • 48592 - GroEL equatorial domain-like
  • 54849 - GroEL-intermediate domain like
  • 0.0000009734Direct
    51905,55424
  • 51905 - FAD/NAD(P)-binding domain
  • 55424 - FAD/NAD-linked reductases, dimerisation (C-terminal) domain
  • 0.00009895Direct
    52833,47616
  • 52833 - Thioredoxin-like
  • 47616 - GST C-terminal domain-like
  • 0.07376Inherited

    (show details)
    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    50729,47473,51695
  • 50729 - PH domain-like
  • 47473 - EF-hand
  • 51695 - PLC-like phosphodiesterases
  • 0Direct
    56968,48431,56968
  • 56968 - Lipovitellin-phosvitin complex; beta-sheet shell regions
  • 48431 - Lipovitellin-phosvitin complex, superhelical domain
  • 56968 - Lipovitellin-phosvitin complex; beta-sheet shell regions
  • 0.00000001349Direct
    48592,54849,52029
  • 48592 - GroEL equatorial domain-like
  • 54849 - GroEL-intermediate domain like
  • 52029 - GroEL apical domain-like
  • 0.0000009734Direct


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
    Plot tree as:   Download Newick format tree:
    (show help)