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Worm Phenotype (WP): organ system development variant

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Root: WP Hierarchy (worm phenotype from Wormbase Release WS226)

Shortest distance to current term (+ for parents, - for children) WP term [WP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + 2:   Variant [WBPhenotype:0000886] <4>
+ 1:   development variant [WBPhenotype:0000518] <7>(506|577) (506|246|68)
0:   organ system development variant [WBPhenotype:0000530] <10>(78|72) (80|31|12)
- 1:   reproductive system development variant [WBPhenotype:0000624] <10>(47|39) (48|20|8)
- 1:   nervous system development variant [WBPhenotype:0000623] <7>(8|6) (8|2|1)
- 1:   alimentary system development variant [WBPhenotype:0000617] <6>(12|11) (13|4|3)
- 1:   muscle system development variant [WBPhenotype:0000622] <5>(8|5) (8|2|1)
- 1:   coelomic system development variant [WBPhenotype:0000618] <3>(1|2) (1|0|0)
- 1:   epithelial system development variant [WBPhenotype:0000619] <3>(14|13) (14|5|1)
- 1:   ectopic organ [WBPhenotype:0002498] <2>(0|0) (0|0|0)
- 1:   excretory secretory system development variant [WBPhenotype:0000620] <2>(6|6) (6|1|0)
- 1:   organ senescence variant [WBPhenotype:0001740](0|0) (0|0|0)
- 1:   tube morphogenesis variant [WBPhenotype:0001848](0|0) (0|0|0)


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Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
C-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
Integrin alpha N-terminal domain0Direct
N-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
ArfGap/RecO-like zinc finger0Direct
Frizzled cysteine-rich domain0Direct
14-3-3 protein0Direct
ARM repeat0.0000000000001555Direct
"Winged helix" DNA-binding domain0.000000000001055Direct
P-loop containing nucleoside triphosphate hydrolases0.000000000001338Direct
Immunoglobulin0.00000000003795Direct
RNA-binding domain, RBD0.0000000002482Direct
EGF/Laminin0.000000002433Direct
PH domain-like0.00000000637Direct
Homeodomain-like0.0000000108Direct
Bromodomain0.00000002615Direct
Fibronectin type III0.0000003063Direct
WD40 repeat-like0.0000003111Direct
Sm-like ribonucleoproteins0.0000006969Direct
PYP-like sensor domain (PAS domain)0.00001462Direct
Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor0.00001587Direct
Growth factor receptor domain0.00001921Direct
HLH, helix-loop-helix DNA-binding domain0.00002711Direct
Tubulin C-terminal domain-like0.00003554Direct
FYVE/PHD zinc finger0.00008432Direct
Sec7 domain0.0001153Direct
Tubulin nucleotide-binding domain-like0.0001554Direct
Band 7/SPFH domain0.0001731Direct
Protein kinase-like (PK-like)0.0002138Direct
Activating enzymes of the ubiquitin-like proteins0.0003174Direct
SNARE-like0.0003473Direct
Intermediate filament protein, coiled coil region0.0003771Direct
HMG-box0.0004908Direct
KA1-like0.0005759Direct
Plexin repeat0.0005759Direct
Sec1/munc18-like (SM) proteins0.0005759Direct
Sema domain0.0005759Direct
Myosin rod fragments0.0008087Direct
GroEL equatorial domain-like0.0008087Direct
Cullin repeat-like0.0008087Direct
GroEL-intermediate domain like0.0008087Direct
E2F-DP heterodimerization region0.0008143Direct
Integrin domains0.0008143Direct
Cdc48 domain 2-like0.0008143Direct
ADC-like0.0008143Direct
Cullin homology domain0.001689Inherited
GroEL apical domain-like0.00172Inherited
Calponin-homology domain, CH-domain0.001738Inherited
beta-beta-alpha zinc fingers0.002925Inherited
Lamin A/C globular tail domain0.00324Inherited
F1F0 ATP synthase subunit C0.00335Inherited
CCCH zinc finger0.003615Inherited
Troponin coil-coiled subunits0.003821Inherited
Cyclin-like0.004846Inherited
Arginase/deacetylase0.00727Inherited
Histone-fold0.008Inherited
Nucleic acid-binding proteins0.008268Inherited
SMAD MH1 domain0.008374Inherited
PDZ domain-like0.01328Inherited
TPR-like0.02082Inherited
Chromo domain-like0.02279Inherited
Concanavalin A-like lectins/glucanases0.03411Inherited
BAR/IMD domain-like0.03816Inherited
N-terminal nucleophile aminohydrolases (Ntn hydrolases)0.04652Inherited
HIT/MYND zinc finger-like0.05434Inherited
vWA-like0.07252Inherited
Ankyrin repeat0.09308Inherited
SMAD/FHA domain0.1245Inherited
SET domain0.1531Inherited
Ubiquitin-like0.1576Inherited
TSP-1 type 1 repeat0.1707Inherited
Cadherin-like0.2029Inherited
Cystine-knot cytokines0.3096Inherited
ABC transporter transmembrane region0.3328Inherited
Acyl-CoA N-acyltransferases (Nat)0.3876Inherited
Voltage-gated potassium channels0.3882Inherited
Nucleotide-diphospho-sugar transferases0.7295Inherited
F-box domain1Inherited
NAD(P)-binding Rossmann-fold domains1Inherited


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Family

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SCOP termFDR (all)Annotation (direct or inherited)
N-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
Mo25 protein0Direct
Frizzled cysteine-rich domain0Direct
Laminin-type module0Direct
Pyk2-associated protein beta ARF-GAP domain0Direct
Integrin domains0Direct
C-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
POU-specific domain0Direct
14-3-3 protein0Direct
Canonical RBD0.000000008366Direct
Homeodomain0.00000009118Direct
Bromodomain0.0000001497Direct
Pleckstrin-homology domain (PH domain)0.00000368Direct
Sm motif of small nuclear ribonucleoproteins, SNRNP0.000003752Direct
Fibronectin type III0.000004164Direct
Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor0.00003401Direct
I set domains0.00006718Direct
Tubulin, C-terminal domain0.0001286Direct
Band 7/SPFH domain0.0001368Direct
Erythroid transcription factor GATA-10.0001368Direct
HLH, helix-loop-helix DNA-binding domain0.000187Direct
Sema domain0.0002079Direct
Sec7 domain0.0002079Direct
WD40-repeat0.0003621Direct
Pumilio repeat0.0003802Direct
ets domain0.0003802Direct
Tubulin, GTPase domain0.0004719Direct
Intermediate filament protein, coiled coil region0.0008777Direct
Proteasome subunits0.0009131Direct
DNA replication initiator (cdc21/cdc54) N-terminal domain0.001022Inherited
Plexin repeat0.001022Inherited
Cullin repeat0.001022Inherited
SCF ubiquitin ligase complex WHB domain0.001022Inherited
PHD domain0.00118Inherited
PDZ domain0.001221Inherited
Cdc48 N-terminal domain-like0.00125Inherited
DEATH domain, DD0.00125Inherited
Cell cycle transcription factor e2f-dp0.00125Inherited
Cdc48 domain 2-like0.00125Inherited
HMG-box0.001425Inherited
Myosin rod fragments0.001634Inherited
G proteins0.002312Inherited
Protein kinases, catalytic subunit0.002473Inherited
Clathrin coat assembly domain0.002973Inherited
Clathrin adaptor core protein0.002973Inherited
Cullin homology domain0.002973Inherited
Paired domain0.00343Inherited
F1F0 ATP synthase subunit C0.005131Inherited
Transforming growth factor (TGF)-beta0.005131Inherited
DEP domain0.005131Inherited
Calponin-homology domain, CH-domain0.005725Inherited
Laminin G-like module0.00635Inherited
Histone deacetylase, HDAC0.006636Inherited
Group II chaperonin (CCT, TRIC), ATPase domain0.006636Inherited
Histone lysine methyltransferases0.006753Inherited
CCCH zinc finger0.01034Inherited
Group II chaperonin (CCT, TRIC), apical domain0.01254Inherited
RecA protein-like (ATPase-domain)0.01278Inherited
SMAD MH1 domain0.01278Inherited
N-acetyl transferase, NAT0.01863Inherited
EGF-type module0.03516Inherited
SMAD domain0.04214Inherited
Myb/SANT domain0.04214Inherited
Armadillo repeat0.04768Inherited
Nucleosome core histones0.05525Inherited
Lamin A/C globular tail domain0.06443Inherited
Cadherin0.1581Inherited
TBP-associated factors, TAFs0.1581Inherited
Chromo domain0.1971Inherited
Ankyrin repeat0.2379Inherited
ABC transporter transmembrane region0.3731Inherited
ABC transporter ATPase domain-like0.6151Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
14-3-3 protein0Direct
Frizzled cysteine-rich domain0Direct
ArfGap/RecO-like zinc finger0Direct
N-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
Integrin alpha N-terminal domain0Direct
C-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
ARM repeat0.0000000000001231Direct
"Winged helix" DNA-binding domain0.0000000000008369Direct
P-loop containing nucleoside triphosphate hydrolases0.000000000001062Direct
Immunoglobulin0.00000000003022Direct
RNA-binding domain, RBD0.0000000001981Direct
EGF/Laminin0.000000001949Direct
PH domain-like0.000000005112Direct
Homeodomain-like0.000000008672Direct
Bromodomain0.00000002105Direct
Fibronectin type III0.000000248Direct
WD40 repeat-like0.0000002519Direct
Sm-like ribonucleoproteins0.0000005666Direct
PYP-like sensor domain (PAS domain)0.00001198Direct
Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor0.00001301Direct
Growth factor receptor domain0.00001576Direct
HLH, helix-loop-helix DNA-binding domain0.00002227Direct
Tubulin C-terminal domain-like0.00002923Direct
FYVE/PHD zinc finger0.00006956Direct
Sec7 domain0.00009521Direct
Tubulin nucleotide-binding domain-like0.0001284Direct
Band 7/SPFH domain0.000143Direct
Protein kinase-like (PK-like)0.0001768Direct
Activating enzymes of the ubiquitin-like proteins0.0002633Direct
SNARE-like0.000288Direct
Intermediate filament protein, coiled coil region0.0003129Direct
HMG-box0.0004081Direct
Plexin repeat0.0004797Direct
Sema domain0.0004797Direct
Sec1/munc18-like (SM) proteins0.0004797Direct
KA1-like0.0004797Direct
GroEL-intermediate domain like0.0006766Direct
GroEL equatorial domain-like0.0006766Direct
Cullin repeat-like0.0006766Direct
Myosin rod fragments0.0006766Direct
E2F-DP heterodimerization region0.0006811Direct
Integrin domains0.0006811Direct
ADC-like0.0006811Direct
Cdc48 domain 2-like0.0006811Direct
C2 domain (Calcium/lipid-binding domain, CaLB)0.0009316Direct
Cullin homology domain0.001421Inherited
GroEL apical domain-like0.001447Inherited
Calponin-homology domain, CH-domain0.001462Inherited
beta-beta-alpha zinc fingers0.002477Inherited
Lamin A/C globular tail domain0.002746Inherited
F1F0 ATP synthase subunit C0.002841Inherited
CCCH zinc finger0.003068Inherited
Troponin coil-coiled subunits0.003246Inherited
Cyclin-like0.004125Inherited
Arginase/deacetylase0.006229Inherited
Histone-fold0.006864Inherited
Nucleic acid-binding proteins0.007098Inherited
SMAD MH1 domain0.00719Inherited
beta and beta-prime subunits of DNA dependent RNA-polymerase0.00719Inherited
PDZ domain-like0.01148Inherited
TPR-like0.01814Inherited
Chromo domain-like0.01989Inherited
Concanavalin A-like lectins/glucanases0.03002Inherited
BAR/IMD domain-like0.03369Inherited
N-terminal nucleophile aminohydrolases (Ntn hydrolases)0.04121Inherited
HIT/MYND zinc finger-like0.04827Inherited
vWA-like0.06491Inherited
Ankyrin repeat0.08386Inherited
SMAD/FHA domain0.1131Inherited
SET domain0.14Inherited
Ubiquitin-like0.1442Inherited
TSP-1 type 1 repeat0.1567Inherited
Cadherin-like0.1871Inherited
Cystine-knot cytokines0.2901Inherited
ABC transporter transmembrane region0.3129Inherited
Acyl-CoA N-acyltransferases (Nat)0.3671Inherited
Voltage-gated potassium channels0.3676Inherited
Nucleotide-diphospho-sugar transferases0.7091Inherited
NAD(P)-binding Rossmann-fold domains1Inherited
F-box domain1Inherited

(show details)
Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
46785,144074
  • 46785 - "Winged helix" DNA-binding domain
  • 144074 - E2F-DP heterodimerization region
  • 0Direct
    50692,54585
  • 50692 - ADC-like
  • 54585 - Cdc48 domain 2-like
  • 0Direct
    54585,52540
  • 54585 - Cdc48 domain 2-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    57863,48403
  • 57863 - ArfGap/RecO-like zinc finger
  • 48403 - Ankyrin repeat
  • 0Direct
    52540,47917
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 47917 - C-terminal domain of alpha and beta subunits of F1 ATP synthase
  • 0Direct
    48726,48726
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 0.0000000002504Direct
    57196,57196
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.00000002696Direct
    48726,49265
  • 48726 - Immunoglobulin
  • 49265 - Fibronectin type III
  • 0.00002923Direct
    54928,54928
  • 54928 - RNA-binding domain, RBD
  • 54928 - RNA-binding domain, RBD
  • 0.00008028Direct
    48371,48371
  • 48371 - ARM repeat
  • 48371 - ARM repeat
  • 0.0001284Direct
    52490,55307
  • 52490 - Tubulin nucleotide-binding domain-like
  • 55307 - Tubulin C-terminal domain-like
  • 0.0001284Direct
    49265,49265
  • 49265 - Fibronectin type III
  • 49265 - Fibronectin type III
  • 0.0002633Direct
    47954,47954
  • 47954 - Cyclin-like
  • 47954 - Cyclin-like
  • 0.000288Direct
    75632,46785
  • 75632 - Cullin homology domain
  • 46785 - "Winged helix" DNA-binding domain
  • 0.0004797Direct
    74788,75632
  • 74788 - Cullin repeat-like
  • 75632 - Cullin homology domain
  • 0.0004797Direct
    54849,52029
  • 54849 - GroEL-intermediate domain like
  • 52029 - GroEL apical domain-like
  • 0.0006766Direct
    48592,54849
  • 48592 - GroEL equatorial domain-like
  • 54849 - GroEL-intermediate domain like
  • 0.0006766Direct
    81333,81333
  • 81333 - F1F0 ATP synthase subunit C
  • 81333 - F1F0 ATP synthase subunit C
  • 0.0006811Direct
    55550,50044
  • 55550 - SH2 domain
  • 50044 - SH3-domain
  • 0.0006811Direct
    101912,103575
  • 101912 - Sema domain
  • 103575 - Plexin repeat
  • 0.0006811Direct
    64356,49447
  • 64356 - SNARE-like
  • 49447 - Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor
  • 0.0006811Direct
    49265,48726
  • 49265 - Fibronectin type III
  • 48726 - Immunoglobulin
  • 0.0006811Direct
    48452,48452
  • 48452 - TPR-like
  • 48452 - TPR-like
  • 0.0007309Direct
    57903,57903
  • 57903 - FYVE/PHD zinc finger
  • 57903 - FYVE/PHD zinc finger
  • 0.002841Inherited
    52113,52113
  • 52113 - BRCT domain
  • 52113 - BRCT domain
  • 0.00719Inherited
    64593,74853
  • 64593 - Intermediate filament protein, coiled coil region
  • 74853 - Lamin A/C globular tail domain
  • 0.01426Inherited
    54160,54160
  • 54160 - Chromo domain-like
  • 54160 - Chromo domain-like
  • 0.01426Inherited
    90229,90229
  • 90229 - CCCH zinc finger
  • 90229 - CCCH zinc finger
  • 0.0309Inherited
    52540,90123
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 90123 - ABC transporter transmembrane region
  • 0.03826Inherited
    49313,49313
  • 49313 - Cadherin-like
  • 49313 - Cadherin-like
  • 0.07605Inherited
    90123,52540
  • 90123 - ABC transporter transmembrane region
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.3129Inherited

    (show details)
    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    50692,54585,52540
  • 50692 - ADC-like
  • 54585 - Cdc48 domain 2-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    54585,52540,52540
  • 54585 - Cdc48 domain 2-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    48726,48726,48726
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 0.00005948Direct
    57196,57196,57196
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.00006484Direct
    48726,48726,49265
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 49265 - Fibronectin type III
  • 0.0001324Direct
    74788,75632,46785
  • 74788 - Cullin repeat-like
  • 75632 - Cullin homology domain
  • 46785 - "Winged helix" DNA-binding domain
  • 0.0004797Direct
    48592,54849,52029
  • 48592 - GroEL equatorial domain-like
  • 54849 - GroEL-intermediate domain like
  • 52029 - GroEL apical domain-like
  • 0.0006766Direct
    81296,81296,81296
  • 81296 - E set domains
  • 81296 - E set domains
  • 81296 - E set domains
  • 0.0006811Direct
    48452,48452,48452
  • 48452 - TPR-like
  • 48452 - TPR-like
  • 48452 - TPR-like
  • 0.0006811Direct
    52540,90123,52540
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 90123 - ABC transporter transmembrane region
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.03826Inherited
    90123,52540,90123
  • 90123 - ABC transporter transmembrane region
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 90123 - ABC transporter transmembrane region
  • 0.03826Inherited
    49313,49313,49313
  • 49313 - Cadherin-like
  • 49313 - Cadherin-like
  • 49313 - Cadherin-like
  • 0.07605Inherited


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
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