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Worm Phenotype (WP): muscle system physiology variant

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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Root: WP Hierarchy (worm phenotype from Wormbase Release WS226)

Shortest distance to current term (+ for parents, - for children) WP term [WP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + 3:   Variant [WBPhenotype:0000886] <2>
+ + 2:   physiology variant [WBPhenotype:0000519] <14>(510|587) (510|248|68)
+ 1:   organ system physiology variant [WBPhenotype:0000575] <8>(445|529) (445|229|63)
0:   muscle system physiology variant [WBPhenotype:0000611] <4>(27|29) (29|14|5)
- 1:   muscle cell physiology variant [WBPhenotype:0000990] <8>(21|22) (22|13|4)
- 1:   muscle dystrophy [WBPhenotype:0000548] <2>(5|4) (5|0|0)
- 1:   body wall muscle contraction abnormal [WBPhenotype:0000153](0|0) (0|0|0)
- 1:   head muscle contraction variant [WBPhenotype:0000423](0|0) (0|0|0)


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Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
PH domain-like0Direct
SH3-domain0.0000000000008485Direct
SH2 domain0.00000000002824Direct
PLC-like phosphodiesterases0.00000001558Direct
Frizzled cysteine-rich domain0.00000002057Direct
C2 domain (Calcium/lipid-binding domain, CaLB)0.00000004153Direct
Growth factor receptor domain0.0000002399Direct
Ubiquitin-like0.0000006786Direct
Second domain of FERM0.000004214Direct
Protein kinase-like (PK-like)0.000004275Direct
Tropomyosin0.000007687Direct
Spectrin repeat0.000007687Direct
Calponin-homology domain, CH-domain0.000009303Direct
EF-hand0.0000419Direct
EGF/Laminin0.00008153Direct
Myosin rod fragments0.00008995Direct
GTPase activation domain, GAP0.0001293Direct
Lamin A/C globular tail domain0.0002054Direct
Intermediate filament protein, coiled coil region0.0002196Direct
PDZ domain-like0.0002396Direct
Cysteine-rich domain0.0002454Direct
cAMP-binding domain-like0.000602Direct
DBL homology domain (DH-domain)0.001624Inherited
Voltage-gated potassium channels0.002167Inherited
(Phosphotyrosine protein) phosphatases II0.002533Inherited
Actin-like ATPase domain0.003474Inherited
"Winged helix" DNA-binding domain0.2707Inherited


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Family

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SCOP termFDR (all)Annotation (direct or inherited)
Mammalian PLC0Direct
SH3-domain0.00000000002327Direct
PLC-like (P variant)0.000000000181Direct
Pleckstrin-homology domain (PH domain)0.0000000005112Direct
SH2 domain0.0000000005877Direct
Frizzled cysteine-rich domain0.00000004976Direct
EF-hand modules in multidomain proteins0.00000004976Direct
LIM domain0.0000002652Direct
Laminin-type module0.0000002867Direct
PDZ domain0.000006117Direct
DEP domain0.00000796Direct
Second domain of FERM0.000008246Direct
Third domain of FERM0.0000103Direct
Spectrin repeat0.0000103Direct
Tropomyosin0.00001822Direct
First domain of FERM0.00002282Direct
Calponin-homology domain, CH-domain0.00003269Direct
Protein kinases, catalytic subunit0.00003967Direct
Phosphotyrosine-binding domain (PTB)0.00004733Direct
Growth factor receptor domain0.0001032Direct
Lamin A/C globular tail domain0.0001581Direct
Myosin rod fragments0.0001696Direct
Intermediate filament protein, coiled coil region0.0004111Direct
BCR-homology GTPase activation domain (BH-domain)0.0006597Direct
cAMP-binding domain0.0008287Direct
Actin/HSP700.001082Inherited
DBL homology domain (DH-domain)0.00299Inherited
I set domains0.003669Inherited
Voltage-gated potassium channels0.01475Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
PH domain-like0Direct
SH3-domain0.000000000000668Direct
SH2 domain0.00000000002232Direct
PLC-like phosphodiesterases0.00000001242Direct
Frizzled cysteine-rich domain0.00000001642Direct
C2 domain (Calcium/lipid-binding domain, CaLB)0.00000003322Direct
Growth factor receptor domain0.0000001928Direct
Ubiquitin-like0.0000005476Direct
Second domain of FERM0.000003423Direct
Protein kinase-like (PK-like)0.000003473Direct
Tropomyosin0.000006252Direct
Spectrin repeat0.000006252Direct
Calponin-homology domain, CH-domain0.000007567Direct
EF-hand0.00003424Direct
EGF/Laminin0.00006673Direct
Myosin rod fragments0.00007368Direct
GTPase activation domain, GAP0.0001061Direct
Lamin A/C globular tail domain0.0001688Direct
Intermediate filament protein, coiled coil region0.0001805Direct
PDZ domain-like0.000197Direct
Cysteine-rich domain0.0002018Direct
cAMP-binding domain-like0.0004987Direct
Fibronectin type III0.0008674Direct
DBL homology domain (DH-domain)0.001358Inherited
Voltage-gated potassium channels0.00182Inherited
(Phosphotyrosine protein) phosphatases II0.002133Inherited
Actin-like ATPase domain0.002939Inherited
BAR/IMD domain-like0.006099Inherited
"Winged helix" DNA-binding domain0.2524Inherited

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Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
47473,51695
  • 47473 - EF-hand
  • 51695 - PLC-like phosphodiesterases
  • 0Direct
    50729,47473
  • 50729 - PH domain-like
  • 47473 - EF-hand
  • 0Direct
    51695,49562
  • 51695 - PLC-like phosphodiesterases
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 0Direct
    57716,57716
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 0.0000000003103Direct
    57196,57196
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.0000004929Direct
    47031,50729
  • 47031 - Second domain of FERM
  • 50729 - PH domain-like
  • 0.000000528Direct
    55550,50044
  • 55550 - SH2 domain
  • 50044 - SH3-domain
  • 0.0000007077Direct
    54236,47031
  • 54236 - Ubiquitin-like
  • 47031 - Second domain of FERM
  • 0.0000164Direct
    50044,50044
  • 50044 - SH3-domain
  • 50044 - SH3-domain
  • 0.00002191Direct
    64593,74853
  • 64593 - Intermediate filament protein, coiled coil region
  • 74853 - Lamin A/C globular tail domain
  • 0.00002191Direct
    46966,46966
  • 46966 - Spectrin repeat
  • 46966 - Spectrin repeat
  • 0.00002191Direct
    50044,55550
  • 50044 - SH3-domain
  • 55550 - SH2 domain
  • 0.00002191Direct
    53067,53067
  • 53067 - Actin-like ATPase domain
  • 53067 - Actin-like ATPase domain
  • 0.001535Inherited
    55550,56112
  • 55550 - SH2 domain
  • 56112 - Protein kinase-like (PK-like)
  • 0.004242Inherited

    (show details)
    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    50729,47473,51695
  • 50729 - PH domain-like
  • 47473 - EF-hand
  • 51695 - PLC-like phosphodiesterases
  • 0Direct
    57716,57716,57716
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 0.0000000002876Direct
    46966,46966,46966
  • 46966 - Spectrin repeat
  • 46966 - Spectrin repeat
  • 46966 - Spectrin repeat
  • 0.000009746Direct
    54236,47031,50729
  • 54236 - Ubiquitin-like
  • 47031 - Second domain of FERM
  • 50729 - PH domain-like
  • 0.0000104Direct
    57196,57196,57196
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.00003614Direct


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
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