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Worm Phenotype (WP): reproductive system development variant

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Root: WP Hierarchy (worm phenotype from Wormbase Release WS226)

Shortest distance to current term (+ for parents, - for children) WP term [WP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + + 4:   Variant [WBPhenotype:0000886] <2>
+ + + 3:   physiology variant [WBPhenotype:0000519] <14>(510|587) (510|248|68)
+ + 2:   development variant [WBPhenotype:0000518] <6>(508|585) (508|248|68)
+ 1:   organ system development variant [WBPhenotype:0000530] <10>(79|72) (80|33|13)
0:   reproductive system development variant [WBPhenotype:0000624] <10>(48|41) (49|22|9)
- 1:   vulva development variant [WBPhenotype:0000699] <3>(15|13) (15|3|1)
- 1:   copulatory structure development variant [WBPhenotype:0000429] <2>(0|0) (0|0|0)
- 1:   gonad development variant [WBPhenotype:0000691] <2>(20|17) (21|9|5)
- 1:   sex muscle development variant [WBPhenotype:0000669] <2>(0|0) (0|0|0)
- 1:   vulva uterus connection defective [WBPhenotype:0000283] <2>(10|8) (10|6|3)
- 1:   feminization of XX and XO animals [WBPhenotype:0000687] <1>(1|0) (1|0|0)
- 1:   fewer eggs in utero [WBPhenotype:0002019](0|0) (0|0|0)
- 1:   gonad migration variant [WBPhenotype:0000690](0|1) (0|0|0)
- 1:   no uterus [WBPhenotype:0000401](0|0) (0|0|0)
- 1:   sexual maturation defective [WBPhenotype:0000434](0|0) (0|0|0)


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Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
C-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
Integrin alpha N-terminal domain0Direct
N-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
Cullin repeat-like0.00003929Direct
Sema domain0.00004282Direct
Plexin repeat0.00004282Direct
ADC-like0.0000992Direct
E2F-DP heterodimerization region0.0000992Direct
Cdc48 domain 2-like0.0000992Direct
Integrin domains0.0000992Direct
Cullin homology domain0.0001353Direct
F1F0 ATP synthase subunit C0.0004377Direct
Sec63 N-terminal domain-like0.0004377Direct
Immunoglobulin0.0005491Direct
Chromo domain-like0.001199Inherited
N-terminal nucleophile aminohydrolases (Ntn hydrolases)0.002121Inherited
Bromodomain0.004946Inherited
Sm-like ribonucleoproteins0.004946Inherited
HMG-box0.02371Inherited
Fibronectin type III0.02496Inherited
FYVE/PHD zinc finger0.03627Inherited
SET domain0.03977Inherited
Cadherin-like0.04576Inherited
Acyl-CoA N-acyltransferases (Nat)0.05147Inherited
EGF/Laminin0.05357Inherited
WD40 repeat-like0.05598Inherited
Cyclin-like0.09097Inherited
Nucleic acid-binding proteins0.1038Inherited
GroEL-intermediate domain like0.1092Inherited
GroEL equatorial domain-like0.1092Inherited
GroEL apical domain-like0.1092Inherited
Arginase/deacetylase0.1789Inherited
HIT/MYND zinc finger-like0.1789Inherited
Cystine-knot cytokines0.1789Inherited
P-loop containing nucleoside triphosphate hydrolases0.2587Inherited
Protein kinase-like (PK-like)0.284Inherited
TPR-like0.4371Inherited
"Winged helix" DNA-binding domain0.4881Inherited
SNARE-like0.492Inherited
Nucleotide-diphospho-sugar transferases0.5417Inherited
Intermediate filament protein, coiled coil region0.6252Inherited
TSP-1 type 1 repeat0.6675Inherited
Tubulin nucleotide-binding domain-like0.9044Inherited
NAD(P)-binding Rossmann-fold domains0.9321Inherited
F-box domain0.9564Inherited
Tubulin C-terminal domain-like0.9753Inherited
Homeodomain-like0.9915Inherited
RNA-binding domain, RBD1Inherited


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Family

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SCOP termFDR (all)Annotation (direct or inherited)
C-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
Integrin domains0Direct
N-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
PHD domain0.00001112Direct
Sema domain0.00001394Direct
Proteasome subunits0.00001811Direct
DNA replication initiator (cdc21/cdc54) N-terminal domain0.00007454Direct
Cullin repeat0.00007454Direct
SCF ubiquitin ligase complex WHB domain0.00007454Direct
Plexin repeat0.00007454Direct
Cdc48 domain 2-like0.0001473Direct
Cell cycle transcription factor e2f-dp0.0001473Direct
Cdc48 N-terminal domain-like0.0001473Direct
Cullin homology domain0.0002332Direct
Transforming growth factor (TGF)-beta0.0006488Direct
F1F0 ATP synthase subunit C0.0006488Direct
N-acetyl transferase, NAT0.0008534Direct
RecA protein-like (ATPase-domain)0.001734Inherited
Bromodomain0.003831Inherited
Armadillo repeat0.005251Inherited
I set domains0.006562Inherited
Sm motif of small nuclear ribonucleoproteins, SNRNP0.01127Inherited
HMG-box0.01927Inherited
Fibronectin type III0.02017Inherited
TBP-associated factors, TAFs0.0314Inherited
Cadherin0.0314Inherited
Histone lysine methyltransferases0.03292Inherited
Chromo domain0.0413Inherited
Pumilio repeat0.05581Inherited
WD40-repeat0.057Inherited
Cyclin0.1187Inherited
Group II chaperonin (CCT, TRIC), apical domain0.1579Inherited
Clathrin adaptor core protein0.1579Inherited
Histone deacetylase, HDAC0.1579Inherited
Group II chaperonin (CCT, TRIC), ATPase domain0.1579Inherited
Protein kinases, catalytic subunit0.2562Inherited
PDZ domain0.5936Inherited
Intermediate filament protein, coiled coil region0.5947Inherited
Tubulin, GTPase domain0.8813Inherited
Homeodomain0.9338Inherited
Tubulin, C-terminal domain0.9599Inherited


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Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
N-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
Integrin alpha N-terminal domain0Direct
C-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
Cullin repeat-like0.00003211Direct
Sema domain0.00003499Direct
Plexin repeat0.00003499Direct
Cdc48 domain 2-like0.00008126Direct
Integrin domains0.00008126Direct
E2F-DP heterodimerization region0.00008126Direct
ADC-like0.00008126Direct
Cullin homology domain0.000111Direct
F1F0 ATP synthase subunit C0.0003616Direct
Sec63 N-terminal domain-like0.0003616Direct
Immunoglobulin0.0004548Direct
beta and beta-prime subunits of DNA dependent RNA-polymerase0.0009803Direct
Chromo domain-like0.0009993Direct
N-terminal nucleophile aminohydrolases (Ntn hydrolases)0.001781Inherited
Bromodomain0.004202Inherited
Sm-like ribonucleoproteins0.004202Inherited
HMG-box0.0207Inherited
Fibronectin type III0.02183Inherited
FYVE/PHD zinc finger0.03194Inherited
SET domain0.03506Inherited
Cadherin-like0.04046Inherited
Acyl-CoA N-acyltransferases (Nat)0.04565Inherited
EGF/Laminin0.04757Inherited
WD40 repeat-like0.04974Inherited
Cyclin-like0.08188Inherited
Nucleic acid-binding proteins0.09382Inherited
GroEL equatorial domain-like0.0988Inherited
GroEL apical domain-like0.0988Inherited
GroEL-intermediate domain like0.0988Inherited
Cystine-knot cytokines0.1643Inherited
HIT/MYND zinc finger-like0.1643Inherited
Arginase/deacetylase0.1643Inherited
P-loop containing nucleoside triphosphate hydrolases0.2407Inherited
Protein kinase-like (PK-like)0.2654Inherited
TPR-like0.4163Inherited
"Winged helix" DNA-binding domain0.4665Inherited
SNARE-like0.4703Inherited
Nucleotide-diphospho-sugar transferases0.5199Inherited
Intermediate filament protein, coiled coil region0.6032Inherited
TSP-1 type 1 repeat0.6459Inherited
Tubulin nucleotide-binding domain-like0.889Inherited
NAD(P)-binding Rossmann-fold domains0.9183Inherited
F-box domain0.9431Inherited
Tubulin C-terminal domain-like0.9633Inherited
Homeodomain-like0.9809Inherited
RNA-binding domain, RBD1Inherited

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Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
46785,144074
  • 46785 - "Winged helix" DNA-binding domain
  • 144074 - E2F-DP heterodimerization region
  • 0Direct
    52540,47917
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 47917 - C-terminal domain of alpha and beta subunits of F1 ATP synthase
  • 0Direct
    54585,52540
  • 54585 - Cdc48 domain 2-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    50692,54585
  • 50692 - ADC-like
  • 54585 - Cdc48 domain 2-like
  • 0Direct
    48726,48726
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 0.00001764Direct
    74788,75632
  • 74788 - Cullin repeat-like
  • 75632 - Cullin homology domain
  • 0.00003499Direct
    75632,46785
  • 75632 - Cullin homology domain
  • 46785 - "Winged helix" DNA-binding domain
  • 0.00003499Direct
    81333,81333
  • 81333 - F1F0 ATP synthase subunit C
  • 81333 - F1F0 ATP synthase subunit C
  • 0.00008126Direct
    101912,103575
  • 101912 - Sema domain
  • 103575 - Plexin repeat
  • 0.00008126Direct
    55550,50044
  • 55550 - SH2 domain
  • 50044 - SH3-domain
  • 0.00008126Direct
    57903,57903
  • 57903 - FYVE/PHD zinc finger
  • 57903 - FYVE/PHD zinc finger
  • 0.0003616Direct
    54160,54160
  • 54160 - Chromo domain-like
  • 54160 - Chromo domain-like
  • 0.00207Inherited
    49313,49313
  • 49313 - Cadherin-like
  • 49313 - Cadherin-like
  • 0.01356Inherited
    57196,57196
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.06639Inherited
    48726,49265
  • 48726 - Immunoglobulin
  • 49265 - Fibronectin type III
  • 0.08188Inherited
    48452,48452
  • 48452 - TPR-like
  • 48452 - TPR-like
  • 0.08188Inherited
    48592,54849
  • 48592 - GroEL equatorial domain-like
  • 54849 - GroEL-intermediate domain like
  • 0.0988Inherited
    54849,52029
  • 54849 - GroEL-intermediate domain like
  • 52029 - GroEL apical domain-like
  • 0.0988Inherited
    48065,50729
  • 48065 - DBL homology domain (DH-domain)
  • 50729 - PH domain-like
  • 0.0988Inherited
    49265,49265
  • 49265 - Fibronectin type III
  • 49265 - Fibronectin type III
  • 0.0988Inherited
    82895,82895
  • 82895 - TSP-1 type 1 repeat
  • 82895 - TSP-1 type 1 repeat
  • 0.3931Inherited
    52490,55307
  • 52490 - Tubulin nucleotide-binding domain-like
  • 55307 - Tubulin C-terminal domain-like
  • 0.889Inherited

    (show details)
    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    50692,54585,52540
  • 50692 - ADC-like
  • 54585 - Cdc48 domain 2-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    54585,52540,52540
  • 54585 - Cdc48 domain 2-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    74788,75632,46785
  • 74788 - Cullin repeat-like
  • 75632 - Cullin homology domain
  • 46785 - "Winged helix" DNA-binding domain
  • 0.00003499Direct
    48726,48726,48726
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 0.004202Inherited
    49313,49313,49313
  • 49313 - Cadherin-like
  • 49313 - Cadherin-like
  • 49313 - Cadherin-like
  • 0.01356Inherited
    57196,57196,57196
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.0207Inherited
    48726,48726,49265
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 49265 - Fibronectin type III
  • 0.05903Inherited
    48592,54849,52029
  • 48592 - GroEL equatorial domain-like
  • 54849 - GroEL-intermediate domain like
  • 52029 - GroEL apical domain-like
  • 0.0988Inherited
    82895,82895,82895
  • 82895 - TSP-1 type 1 repeat
  • 82895 - TSP-1 type 1 repeat
  • 82895 - TSP-1 type 1 repeat
  • 0.3931Inherited


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
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