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Worm Phenotype (WP): gene expression variant

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Root: WP Hierarchy (worm phenotype from Wormbase Release WS226)

Shortest distance to current term (+ for parents, - for children) WP term [WP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + + + 5:   Variant [WBPhenotype:0000886] <4>
+ + + + 4:   physiology variant [WBPhenotype:0000519] <7>(489|563) (489|241|65)
+ + + 3:   organism physiology variant [WBPhenotype:0000576] <10>(357|420) (358|193|57)
+ + 2:   organism homeostasis metabolism variant [WBPhenotype:0000577] <17>(347|410) (350|191|56)
+ 1:   organism metabolism processing variant [WBPhenotype:0000027] <25>(171|182) (176|81|24)
0:   gene expression variant [WBPhenotype:0000717] <10>(122|134) (129|62|19)
- 1:   RNA expression variant [WBPhenotype:0000113] <10>(19|16) (19|5|0)
- 1:   protein expression variant [WBPhenotype:0000112] <6>(38|44) (41|20|6)
- 1:   dosage compensation variant [WBPhenotype:0000718] <3>(1|0) (1|0|0)
- 1:   transgene expression variant [WBPhenotype:0000306] <3>(84|95) (88|41|13)
- 1:   gene expression level high [WBPhenotype:0000135] <1>(2|2) (2|0|0)
- 1:   gene expression level reduced [WBPhenotype:0000134] <1>(5|3) (5|0|0)
- 1:   drug induced gene expression variant [WBPhenotype:0001838](5|6) (5|2|0)
- 1:   environmental stimuli induced gene expression variant [WBPhenotype:0001861](0|0) (0|0|0)
- 1:   pathogen induced gene expression variant [WBPhenotype:0001857](1|1) (1|0|0)
- 1:   pattern of gene expression variant [WBPhenotype:0000111](0|0) (0|0|0)


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
MIR domain0Direct
HSP90 C-terminal domain0Direct
TK C-terminal domain-like0Direct
Ribosomal proteins S24e, L23 and L15e0Direct
Tubulin nucleotide-binding domain-like0Direct
S-adenosylmethionine synthetase0Direct
Tubulin C-terminal domain-like0Direct
Nop domain0Direct
SMAD MH1 domain0Direct
Helical domain of Sec23/240Direct
JAB1/MPN domain0Direct
14-3-3 protein0Direct
C-terminal, gelsolin-like domain of Sec23/240Direct
Cullin homology domain0Direct
Heat shock protein 70kD (HSP70), C-terminal subdomain0Direct
N-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor0Direct
Cytochrome c0Direct
Heme-dependent catalase-like0Direct
FF domain0Direct
F1F0 ATP synthase subunit C0Direct
Clathrin adaptor appendage domain0Direct
ISP domain0Direct
ValRS/IleRS/LeuRS editing domain0Direct
GroEL equatorial domain-like0Direct
Subdomain of clathrin and coatomer appendage domain0Direct
Class II aaRS ABD-related0Direct
Ribosomal protein L10-like0Direct
Zn-finger domain of Sec23/240Direct
GroEL-intermediate domain like0Direct
Cu,Zn superoxide dismutase-like0Direct
GroEL apical domain-like0Direct
C-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
Epsilon subunit of mitochondrial F1F0-ATP synthase0Direct
Ribosomal protein L10Direct
Class II aaRS and biotin synthetases0.000001696Direct
Acid proteases0.000001696Direct
RING/U-box0.000003233Direct
SNARE-like0.000005035Direct
Translation proteins0.00000832Direct
PAP/OAS1 substrate-binding domain0.00000915Direct
Translation proteins SH3-like domain0.00004613Direct
CCCH zinc finger0.00005127Direct
Cullin repeat-like0.00005916Direct
Arginase/deacetylase0.00005916Direct
Heat shock protein 70kD (HSP70), peptide-binding domain0.00005916Direct
Hect, E3 ligase catalytic domain0.00005916Direct
N-terminal nucleophile aminohydrolases (Ntn hydrolases)0.000112Direct
B-box zinc-binding domain0.0001135Direct
ARM repeat0.0001745Direct
Cyclophilin-like0.0002879Direct
ENTH/VHS domain0.000667Direct
Sm-like ribonucleoproteins0.0007192Direct
L30e-like0.001156Inherited
EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain0.001156Inherited
RNA-binding domain, RBD0.001398Inherited
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases0.001511Inherited
Sec1/munc18-like (SM) proteins0.001908Inherited
beta and beta-prime subunits of DNA dependent RNA-polymerase0.001908Inherited
"Winged helix" DNA-binding domain0.00266Inherited
P-loop containing nucleoside triphosphate hydrolases0.003058Inherited
PAZ domain0.003098Inherited
Ferredoxin reductase-like, C-terminal NADP-linked domain0.003255Inherited
Activating enzymes of the ubiquitin-like proteins0.003255Inherited
Riboflavin synthase domain-like0.003255Inherited
FKBP-like0.00394Inherited
Leucine zipper domain0.00495Inherited
Frizzled cysteine-rich domain0.005902Inherited
4Fe-4S ferredoxins0.005902Inherited
Zn-binding ribosomal proteins0.008884Inherited
Single hybrid motif0.00988Inherited
DHS-like NAD/FAD-binding domain0.009922Inherited
Histone-fold0.01286Inherited
Saposin0.01314Inherited
p53-like transcription factors0.0166Inherited
Cyclin-like0.0166Inherited
FYVE/PHD zinc finger0.01746Inherited
Integrin domains0.01799Inherited
ADC-like0.01799Inherited
Cdc48 domain 2-like0.01799Inherited
SET domain0.01942Inherited
PX domain0.0204Inherited
PH domain-like0.02093Inherited
SH3-domain0.02797Inherited
Homeodomain-like0.0303Inherited
Protein kinase-like (PK-like)0.03099Inherited
UBC-like0.03209Inherited
Actin-like ATPase domain0.04198Inherited
Chaperone J-domain0.04198Inherited
HLH, helix-loop-helix DNA-binding domain0.04816Inherited
dsRNA-binding domain-like0.05031Inherited
Tubby C-terminal domain-like0.06037Inherited
S15/NS1 RNA-binding domain0.06037Inherited
CAD & PB1 domains0.06037Inherited
ARID-like0.06037Inherited
Quinoprotein alcohol dehydrogenase-like0.06215Inherited
Cysteine-rich domain0.06302Inherited
HSP20-like chaperones0.08231Inherited
Ribosomal protein S5 domain 2-like0.09413Inherited
Nucleic acid-binding proteins0.09575Inherited
KA1-like0.1256Inherited
Cysteine proteinases0.1302Inherited
GTPase activation domain, GAP0.1438Inherited
SH2 domain0.1947Inherited
Nucleotidyltransferase0.2063Inherited
Transducin (alpha subunit), insertion domain0.2343Inherited
HMG-box0.2343Inherited
Eukaryotic type KH-domain (KH-domain type I)0.293Inherited
Second domain of FERM0.3364Inherited
Nucleotidylyl transferase0.3902Inherited
Glucocorticoid receptor-like (DNA-binding domain)0.3973Inherited
Intermediate filament protein, coiled coil region0.4348Inherited
C2 domain (Calcium/lipid-binding domain, CaLB)0.4687Inherited
Lamin A/C globular tail domain0.4897Inherited
Spectrin repeat0.4897Inherited
PYP-like sensor domain (PAS domain)0.4897Inherited
Chromo domain-like0.5286Inherited
Ribonuclease H-like0.5461Inherited
FAD/NAD-linked reductases, dimerisation (C-terminal) domain0.5527Inherited
Nuclear receptor ligand-binding domain0.827Inherited
Clavaminate synthase-like0.9262Inherited
ClpP/crotonase1Inherited


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Family

(show details)
SCOP termFDR (all)Annotation (direct or inherited)
Helical domain of Sec23/240Direct
L30e/L7ae ribosomal proteins0Direct
MIR domain0Direct
Epsilon subunit of mitochondrial F1F0-ATP synthase0Direct
SCF ubiquitin ligase complex WHB domain0Direct
Ubiquitin carboxyl-terminal hydrolase UCH-L0Direct
Cullin homology domain0Direct
Adenain-like0Direct
Zn-finger domain of Sec23/240Direct
PDI-like0Direct
FF domain0Direct
Quinoprotein alcohol dehydrogenase-like0Direct
Trunk domain of Sec23/240Direct
Clathrin coat assembly domain0Direct
HSP200Direct
Group II chaperonin (CCT, TRIC), intermediate domain0Direct
Branched-chain alpha-keto acid dehydrogenase beta-subunit, C-terminal-domain0Direct
C-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
ValRS/IleRS/LeuRS editing domain0Direct
ets domain0Direct
Phosphatidylinositol phosphate kinase IIbeta, PIPK IIbeta0Direct
Histone deacetylase, HDAC0Direct
Ribosomal protein L10Direct
RNA-polymerase beta0Direct
Mammalian PLC0Direct
Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor0Direct
Tubulin, GTPase domain0Direct
Cullin repeat0Direct
Proteasome subunits0Direct
Phoshoinositide 3-kinase (PI3K) helical domain0Direct
CAT-like0Direct
SMAD MH1 domain0Direct
14-3-3 protein0Direct
Heat shock protein 90, HSP90, N-terminal domain0Direct
Heat shock protein 70kD (HSP70), C-terminal subdomain0Direct
Acyl-carrier protein (ACP)0Direct
Erythroid transcription factor GATA-10Direct
Phoshoinositide 3-kinase (PI3K), catalytic domain0Direct
RecA protein-like (ATPase-domain)0Direct
POU-specific domain0Direct
S-adenosylmethionine synthetase0Direct
N-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
Cu,Zn superoxide dismutase-like0Direct
Heme-dependent catalases0Direct
Group II chaperonin (CCT, TRIC), apical domain0Direct
Group II chaperonin (CCT, TRIC), ATPase domain0Direct
RNA editing terminal uridyl transferase 2, RET2, domain 20Direct
Integrin domains0Direct
Nop domain0Direct
C-terminal, gelsolin-like domain of Sec23/240Direct
a tRNA synthase domain0Direct
HSP90 C-terminal domain0Direct
MIF4G domain-like0Direct
Tubulin, C-terminal domain0Direct
Anticodon-binding domain of Class II aaRS0Direct
beta-sandwich domain of Sec23/240Direct
Brix domain0Direct
p120GAP domain-like0Direct
Clathrin adaptor core protein0Direct
Hsp90 middle domain0Direct
Sir2 family of transcriptional regulators0Direct
F1F0 ATP synthase subunit C0Direct
Inositol polyphosphate 5-phosphatase (IPP5)0Direct
Actin/HSP700.000000001875Direct
UBC-related0.00000003468Direct
Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain0.0000006818Direct
Pepsin-like0.000001794Direct
Dual specificity phosphatase-like0.000001794Direct
Papain-like0.00002595Direct
Ubiquitin carboxyl-terminal hydrolase, UCH0.00003651Direct
Class I aminoacyl-tRNA synthetases (RS), catalytic domain0.00009981Direct
Hect, E3 ligase catalytic domain0.0002022Direct
Armadillo repeat0.0002056Direct
CCCH zinc finger0.0005201Direct
SMAD domain0.000551Direct
Translational machinery components0.000551Direct
Heat shock protein 70kD (HSP70), peptide-binding domain0.000551Direct
B-box zinc-binding domain0.0006696Direct
Cyclophilin (peptidylprolyl isomerase)0.00144Inherited
TBP-associated factors, TAFs0.00199Inherited
EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain0.00315Inherited
Histone lysine methyltransferases0.003365Inherited
PDZ domain0.00338Inherited
Canonical RBD0.005057Inherited
Sm motif of small nuclear ribonucleoproteins, SNRNP0.005593Inherited
Extended PAW domain0.006297Inherited
FKBP immunophilin/proline isomerase0.01014Inherited
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases0.01014Inherited
Pumilio repeat0.01014Inherited
EF-hand modules in multidomain proteins0.01072Inherited
Frizzled cysteine-rich domain0.01072Inherited
Ubiquitin activating enzymes (UBA)0.01072Inherited
Transforming growth factor (TGF)-beta0.01072Inherited
Elongation factors0.01314Inherited
PAZ domain0.01824Inherited
Homeodomain0.01832Inherited
Cold shock DNA-binding domain-like0.02088Inherited
Leucine zipper domain0.02088Inherited
RING finger domain, C3HC40.02337Inherited
Biotinyl/lipoyl-carrier proteins and domains0.02422Inherited
Anticodon-binding domain0.02838Inherited
Cdc48 N-terminal domain-like0.02838Inherited
Cdc48 domain 2-like0.02838Inherited
Biotin dependent carboxylase carboxyltransferase domain0.02838Inherited
Nucleosome core histones0.03461Inherited
Chaperone J-domain0.04018Inherited
Cyclin0.04098Inherited
HLH, helix-loop-helix DNA-binding domain0.04595Inherited
SH3-domain0.04698Inherited
PX domain0.04766Inherited
PHD domain0.05882Inherited
DEP domain0.09195Inherited
G proteins0.1068Inherited
Pleckstrin-homology domain (PH domain)0.1438Inherited
Protein kinase cysteine-rich domain (cys2, phorbol-binding domain)0.152Inherited
First domain of FERM0.1858Inherited
Extended AAA-ATPase domain0.2171Inherited
Transducin (alpha subunit), insertion domain0.2245Inherited
HMG-box0.2245Inherited
PLC-like (P variant)0.3296Inherited
Third domain of FERM0.3597Inherited
Protein kinases, catalytic subunit0.4133Inherited
Intermediate filament protein, coiled coil region0.4222Inherited
Synaptotagmin-like (S variant)0.4369Inherited
Second domain of FERM0.4369Inherited
LIM domain0.4758Inherited
N-acetyl transferase, NAT0.5143Inherited
SH2 domain0.5292Inherited
Spectrin repeat0.5363Inherited
Lamin A/C globular tail domain0.5363Inherited
Ubiquitin-related0.5649Inherited
Double-stranded RNA-binding domain (dsRBD)0.6202Inherited
Nuclear receptor ligand-binding domain1Inherited
Nuclear receptor1Inherited


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Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
S-adenosylmethionine synthetase0Direct
Zn-finger domain of Sec23/240Direct
Ribosomal protein L10-like0Direct
Class II aaRS ABD-related0Direct
HSP90 C-terminal domain0Direct
Cu,Zn superoxide dismutase-like0Direct
N-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
ValRS/IleRS/LeuRS editing domain0Direct
Subdomain of clathrin and coatomer appendage domain0Direct
FF domain0Direct
Heat shock protein 70kD (HSP70), C-terminal subdomain0Direct
GroEL apical domain-like0Direct
Tubulin nucleotide-binding domain-like0Direct
F1F0 ATP synthase subunit C0Direct
GroEL equatorial domain-like0Direct
14-3-3 protein0Direct
Helical domain of Sec23/240Direct
Clathrin adaptor appendage domain0Direct
Epsilon subunit of mitochondrial F1F0-ATP synthase0Direct
MIR domain0Direct
C-terminal, gelsolin-like domain of Sec23/240Direct
Nop domain0Direct
TK C-terminal domain-like0Direct
Cytochrome c0Direct
Cullin homology domain0Direct
C-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
Tubulin C-terminal domain-like0Direct
Ribosomal protein L10Direct
Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor0Direct
GroEL-intermediate domain like0Direct
ISP domain0Direct
Ribosomal proteins S24e, L23 and L15e0Direct
Heme-dependent catalase-like0Direct
JAB1/MPN domain0Direct
SMAD MH1 domain0Direct
Acid proteases0.000001384Direct
Class II aaRS and biotin synthetases0.000001384Direct
RING/U-box0.000002643Direct
SNARE-like0.000004117Direct
Translation proteins0.000006803Direct
PAP/OAS1 substrate-binding domain0.000007485Direct
Translation proteins SH3-like domain0.00003798Direct
CCCH zinc finger0.00004223Direct
Arginase/deacetylase0.00004874Direct
Hect, E3 ligase catalytic domain0.00004874Direct
Cullin repeat-like0.00004874Direct
Heat shock protein 70kD (HSP70), peptide-binding domain0.00004874Direct
N-terminal nucleophile aminohydrolases (Ntn hydrolases)0.00009249Direct
B-box zinc-binding domain0.00009368Direct
ARM repeat0.0001441Direct
Cyclophilin-like0.0002386Direct
ENTH/VHS domain0.0005567Direct
Sm-like ribonucleoproteins0.0006009Direct
EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain0.0009688Direct
L30e-like0.0009688Direct
RNA-binding domain, RBD0.001174Inherited
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases0.001269Inherited
Sec1/munc18-like (SM) proteins0.001608Inherited
beta and beta-prime subunits of DNA dependent RNA-polymerase0.001608Inherited
"Winged helix" DNA-binding domain0.002249Inherited
P-loop containing nucleoside triphosphate hydrolases0.002591Inherited
PAZ domain0.002624Inherited
Ferredoxin reductase-like, C-terminal NADP-linked domain0.00276Inherited
Riboflavin synthase domain-like0.00276Inherited
Activating enzymes of the ubiquitin-like proteins0.00276Inherited
FKBP-like0.003346Inherited
Leucine zipper domain0.004214Inherited
Frizzled cysteine-rich domain0.005036Inherited
4Fe-4S ferredoxins0.005036Inherited
Zn-binding ribosomal proteins0.007633Inherited
Single hybrid motif0.008506Inherited
DHS-like NAD/FAD-binding domain0.008542Inherited
Histone-fold0.01111Inherited
Saposin0.01135Inherited
Cyclin-like0.01438Inherited
p53-like transcription factors0.01438Inherited
FYVE/PHD zinc finger0.01514Inherited
Cdc48 domain 2-like0.0156Inherited
ADC-like0.0156Inherited
Integrin domains0.0156Inherited
SET domain0.01688Inherited
PX domain0.01776Inherited
PH domain-like0.01824Inherited
SH3-domain0.02451Inherited
Homeodomain-like0.02659Inherited
Protein kinase-like (PK-like)0.02721Inherited
UBC-like0.02819Inherited
PDZ domain-like0.0349Inherited
Actin-like ATPase domain0.03712Inherited
Chaperone J-domain0.03712Inherited
HLH, helix-loop-helix DNA-binding domain0.0427Inherited
dsRNA-binding domain-like0.04462Inherited
S15/NS1 RNA-binding domain0.05374Inherited
Tubby C-terminal domain-like0.05374Inherited
CAD & PB1 domains0.05374Inherited
ARID-like0.05374Inherited
Quinoprotein alcohol dehydrogenase-like0.05539Inherited
Cysteine-rich domain0.05619Inherited
HSP20-like chaperones0.07395Inherited
Ribosomal protein S5 domain 2-like0.08482Inherited
Nucleic acid-binding proteins0.08633Inherited
KA1-like0.1142Inherited
Cysteine proteinases0.1186Inherited
GTPase activation domain, GAP0.1313Inherited
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase0.1542Inherited
SH2 domain0.1791Inherited
Nucleotidyltransferase0.1902Inherited
Transducin (alpha subunit), insertion domain0.217Inherited
HMG-box0.217Inherited
Calponin-homology domain, CH-domain0.2478Inherited
Eukaryotic type KH-domain (KH-domain type I)0.2739Inherited
Second domain of FERM0.3164Inherited
Nucleotidylyl transferase0.3697Inherited
Glucocorticoid receptor-like (DNA-binding domain)0.3763Inherited
Intermediate filament protein, coiled coil region0.4134Inherited
C2 domain (Calcium/lipid-binding domain, CaLB)0.4473Inherited
cAMP-binding domain-like0.4678Inherited
Spectrin repeat0.4678Inherited
Lamin A/C globular tail domain0.4678Inherited
PYP-like sensor domain (PAS domain)0.4678Inherited
Chromo domain-like0.5064Inherited
Ribonuclease H-like0.5242Inherited
FAD/NAD-linked reductases, dimerisation (C-terminal) domain0.5308Inherited
Lipovitellin-phosvitin complex; beta-sheet shell regions0.5966Inherited
Thiamin diphosphate-binding fold (THDP-binding)0.5966Inherited
Lipovitellin-phosvitin complex, superhelical domain0.5966Inherited
Nuclear receptor ligand-binding domain0.8087Inherited
Clavaminate synthase-like0.912Inherited
ClpP/crotonase0.9957Inherited

(show details)
Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
100920,100934
  • 100920 - Heat shock protein 70kD (HSP70), peptide-binding domain
  • 100934 - Heat shock protein 70kD (HSP70), C-terminal subdomain
  • 0Direct
    55973,55973
  • 55973 - S-adenosylmethionine synthetase
  • 55973 - S-adenosylmethionine synthetase
  • 0Direct
    54849,52029
  • 54849 - GroEL-intermediate domain like
  • 52029 - GroEL apical domain-like
  • 0Direct
    75632,46785
  • 75632 - Cullin homology domain
  • 46785 - "Winged helix" DNA-binding domain
  • 0Direct
    52490,55307
  • 52490 - Tubulin nucleotide-binding domain-like
  • 55307 - Tubulin C-terminal domain-like
  • 0Direct
    55681,52954
  • 55681 - Class II aaRS and biotin synthetases
  • 52954 - Class II aaRS ABD-related
  • 0Direct
    49348,55711
  • 49348 - Clathrin adaptor appendage domain
  • 55711 - Subdomain of clathrin and coatomer appendage domain
  • 0Direct
    50692,54585
  • 50692 - ADC-like
  • 54585 - Cdc48 domain 2-like
  • 0Direct
    81811,82754
  • 81811 - Helical domain of Sec23/24
  • 82754 - C-terminal, gelsolin-like domain of Sec23/24
  • 0Direct
    49562,48371
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 48371 - ARM repeat
  • 0Direct
    81333,81333
  • 81333 - F1F0 ATP synthase subunit C
  • 81333 - F1F0 ATP synthase subunit C
  • 0Direct
    55785,55785
  • 55785 - PYP-like sensor domain (PAS domain)
  • 55785 - PYP-like sensor domain (PAS domain)
  • 0Direct
    82919,53300
  • 82919 - Zn-finger domain of Sec23/24
  • 53300 - vWA-like
  • 0Direct
    54585,52540
  • 54585 - Cdc48 domain 2-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    54495,46934
  • 54495 - UBC-like
  • 46934 - UBA-like
  • 0Direct
    50729,56112
  • 50729 - PH domain-like
  • 56112 - Protein kinase-like (PK-like)
  • 0Direct
    54534,54534
  • 54534 - FKBP-like
  • 54534 - FKBP-like
  • 0Direct
    57756,57756
  • 57756 - Retrovirus zinc finger-like domains
  • 57756 - Retrovirus zinc finger-like domains
  • 0Direct
    81698,81698
  • 81698 - FF domain
  • 81698 - FF domain
  • 0Direct
    52518,52922
  • 52518 - Thiamin diphosphate-binding fold (THDP-binding)
  • 52922 - TK C-terminal domain-like
  • 0Direct
    50677,52374
  • 50677 - ValRS/IleRS/LeuRS editing domain
  • 52374 - Nucleotidylyl transferase
  • 0Direct
    51695,49562
  • 51695 - PLC-like phosphodiesterases
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 0Direct
    46785,46785
  • 46785 - "Winged helix" DNA-binding domain
  • 46785 - "Winged helix" DNA-binding domain
  • 0Direct
    52540,47917
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 47917 - C-terminal domain of alpha and beta subunits of F1 ATP synthase
  • 0Direct
    57863,48403
  • 57863 - ArfGap/RecO-like zinc finger
  • 48403 - Ankyrin repeat
  • 0Direct
    50729,47473
  • 50729 - PH domain-like
  • 47473 - EF-hand
  • 0Direct
    64356,49447
  • 64356 - SNARE-like
  • 49447 - Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor
  • 0Direct
    47473,51695
  • 47473 - EF-hand
  • 51695 - PLC-like phosphodiesterases
  • 0Direct
    74788,75632
  • 74788 - Cullin repeat-like
  • 75632 - Cullin homology domain
  • 0Direct
    48592,54849
  • 48592 - GroEL equatorial domain-like
  • 54849 - GroEL-intermediate domain like
  • 0Direct
    81301,81631
  • 81301 - Nucleotidyltransferase
  • 81631 - PAP/OAS1 substrate-binding domain
  • 0.000004117Direct
    53067,100920
  • 53067 - Actin-like ATPase domain
  • 100920 - Heat shock protein 70kD (HSP70), peptide-binding domain
  • 0.00004874Direct
    47954,47954
  • 47954 - Cyclin-like
  • 47954 - Cyclin-like
  • 0.00006128Direct
    48452,48452
  • 48452 - TPR-like
  • 48452 - TPR-like
  • 0.0002388Direct
    54928,54928
  • 54928 - RNA-binding domain, RBD
  • 54928 - RNA-binding domain, RBD
  • 0.0002388Direct
    101690,53098
  • 101690 - PAZ domain
  • 53098 - Ribonuclease H-like
  • 0.0005064Direct
    50447,50465
  • 50447 - Translation proteins
  • 50465 - EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain
  • 0.0009688Direct
    57889,57889
  • 57889 - Cysteine-rich domain
  • 57889 - Cysteine-rich domain
  • 0.0009688Direct
    52540,50447
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 50447 - Translation proteins
  • 0.001414Inherited
    51045,51045
  • 51045 - WW domain
  • 51045 - WW domain
  • 0.001608Inherited
    57850,57845
  • 57850 - RING/U-box
  • 57845 - B-box zinc-binding domain
  • 0.003464Inherited
    48371,56112
  • 48371 - ARM repeat
  • 56112 - Protein kinase-like (PK-like)
  • 0.005036Inherited
    90229,90229
  • 90229 - CCCH zinc finger
  • 90229 - CCCH zinc finger
  • 0.006438Inherited
    50044,55550
  • 50044 - SH3-domain
  • 55550 - SH2 domain
  • 0.007633Inherited
    50044,50044
  • 50044 - SH3-domain
  • 50044 - SH3-domain
  • 0.007633Inherited
    55550,50044
  • 55550 - SH2 domain
  • 50044 - SH3-domain
  • 0.0156Inherited
    63380,52343
  • 63380 - Riboflavin synthase domain-like
  • 52343 - Ferredoxin reductase-like, C-terminal NADP-linked domain
  • 0.02055Inherited
    57850,57850
  • 57850 - RING/U-box
  • 57850 - RING/U-box
  • 0.03262Inherited
    53067,53067
  • 53067 - Actin-like ATPase domain
  • 53067 - Actin-like ATPase domain
  • 0.03712Inherited
    50249,55681
  • 50249 - Nucleic acid-binding proteins
  • 55681 - Class II aaRS and biotin synthetases
  • 0.05374Inherited
    57716,57716
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 0.1458Inherited
    47895,52540
  • 47895 - Transducin (alpha subunit), insertion domain
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.217Inherited
    47031,50729
  • 47031 - Second domain of FERM
  • 50729 - PH domain-like
  • 0.2428Inherited
    52833,52833
  • 52833 - Thioredoxin-like
  • 52833 - Thioredoxin-like
  • 0.3654Inherited
    54236,47031
  • 54236 - Ubiquitin-like
  • 47031 - Second domain of FERM
  • 0.4574Inherited
    64593,74853
  • 64593 - Intermediate filament protein, coiled coil region
  • 74853 - Lamin A/C globular tail domain
  • 0.5308Inherited
    51905,55424
  • 51905 - FAD/NAD(P)-binding domain
  • 55424 - FAD/NAD-linked reductases, dimerisation (C-terminal) domain
  • 0.5308Inherited
    56968,48431
  • 56968 - Lipovitellin-phosvitin complex; beta-sheet shell regions
  • 48431 - Lipovitellin-phosvitin complex, superhelical domain
  • 0.5966Inherited
    46966,46966
  • 46966 - Spectrin repeat
  • 46966 - Spectrin repeat
  • 0.5966Inherited
    48431,56968
  • 48431 - Lipovitellin-phosvitin complex, superhelical domain
  • 56968 - Lipovitellin-phosvitin complex; beta-sheet shell regions
  • 0.5966Inherited
    57196,57196
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.737Inherited
    57424,57424
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 0.9576Inherited

    (show details)
    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    48592,54849,52029
  • 48592 - GroEL equatorial domain-like
  • 54849 - GroEL-intermediate domain like
  • 52029 - GroEL apical domain-like
  • 0Direct
    54585,52540,52540
  • 54585 - Cdc48 domain 2-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    49562,48371,56112
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 48371 - ARM repeat
  • 56112 - Protein kinase-like (PK-like)
  • 0Direct
    74788,75632,46785
  • 74788 - Cullin repeat-like
  • 75632 - Cullin homology domain
  • 46785 - "Winged helix" DNA-binding domain
  • 0Direct
    48452,48452,48452
  • 48452 - TPR-like
  • 48452 - TPR-like
  • 48452 - TPR-like
  • 0Direct
    55973,55973,55973
  • 55973 - S-adenosylmethionine synthetase
  • 55973 - S-adenosylmethionine synthetase
  • 55973 - S-adenosylmethionine synthetase
  • 0Direct
    50692,54585,52540
  • 50692 - ADC-like
  • 54585 - Cdc48 domain 2-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    53067,100920,100934
  • 53067 - Actin-like ATPase domain
  • 100920 - Heat shock protein 70kD (HSP70), peptide-binding domain
  • 100934 - Heat shock protein 70kD (HSP70), C-terminal subdomain
  • 0Direct
    50729,47473,51695
  • 50729 - PH domain-like
  • 47473 - EF-hand
  • 51695 - PLC-like phosphodiesterases
  • 0Direct
    48371,48371,48371
  • 48371 - ARM repeat
  • 48371 - ARM repeat
  • 48371 - ARM repeat
  • 0Direct
    53067,53067,100920
  • 53067 - Actin-like ATPase domain
  • 53067 - Actin-like ATPase domain
  • 100920 - Heat shock protein 70kD (HSP70), peptide-binding domain
  • 0.00004874Direct
    52540,50447,50465
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 50447 - Translation proteins
  • 50465 - EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain
  • 0.0009688Direct
    57850,57850,57850
  • 57850 - RING/U-box
  • 57850 - RING/U-box
  • 57850 - RING/U-box
  • 0.008542Inherited
    54236,47031,50729
  • 54236 - Ubiquitin-like
  • 47031 - Second domain of FERM
  • 50729 - PH domain-like
  • 0.3787Inherited
    57716,57716,57716
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 0.4134Inherited
    52833,52833,52833
  • 52833 - Thioredoxin-like
  • 52833 - Thioredoxin-like
  • 52833 - Thioredoxin-like
  • 0.4134Inherited
    56968,48431,56968
  • 56968 - Lipovitellin-phosvitin complex; beta-sheet shell regions
  • 48431 - Lipovitellin-phosvitin complex, superhelical domain
  • 56968 - Lipovitellin-phosvitin complex; beta-sheet shell regions
  • 0.5966Inherited
    46966,46966,46966
  • 46966 - Spectrin repeat
  • 46966 - Spectrin repeat
  • 46966 - Spectrin repeat
  • 0.5966Inherited
    57424,57424,57424
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 0.9576Inherited


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
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