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Worm Phenotype (WP): cell death variant

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Root: WP Hierarchy (worm phenotype from Wormbase Release WS226)

Shortest distance to current term (+ for parents, - for children) WP term [WP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + 3:   Variant [WBPhenotype:0000886] <4>
+ + 2:   physiology variant [WBPhenotype:0000519] <7>(487|558) (487|240|64)
+ 1:   blast cell physiology variant [WBPhenotype:0000985] <26>(152|154) (153|66|17)
+ 1:   cell physiology variant [WBPhenotype:0000536] <26>(152|154) (153|66|17)
0:   cell death variant [WBPhenotype:0000729] <3>(56|50) (57|16|5)
- 1:   programmed cell death variant [WBPhenotype:0001172] <3>(54|47) (55|15|5)
- 1:   induced cell death variant [WBPhenotype:0001268] <2>(1|2) (1|1|0)
- 1:   cell degeneration [WBPhenotype:0000178] <1>(0|0) (0|0|0)


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Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
RBP11-like subunits of RNA polymerase0Direct
C-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
Clathrin adaptor appendage domain0Direct
DLC0Direct
N-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
VPS9 domain0Direct
PX domain0Direct
Subdomain of clathrin and coatomer appendage domain0Direct
Calpain large subunit, middle domain (domain III)0.000000482Direct
beta and beta-prime subunits of DNA dependent RNA-polymerase0.0000008179Direct
Cullin repeat-like0.000001965Direct
Skp1 dimerisation domain-like0.000008154Direct
Terpenoid cyclases/Protein prenyltransferases0.0001179Direct
Integrin domains0.0001179Direct
FYVE/PHD zinc finger0.0003565Direct
Caspase-like0.000519Direct
Tubby C-terminal domain-like0.000519Direct
Cupredoxins0.000519Direct
Cullin homology domain0.0007784Direct
GroEL apical domain-like0.001511Inherited
GroEL equatorial domain-like0.004097Inherited
GroEL-intermediate domain like0.004097Inherited
Sm-like ribonucleoproteins0.005052Inherited
ENTH/VHS domain0.005052Inherited
Protein kinase-like (PK-like)0.007597Inherited
BAR/IMD domain-like0.012Inherited
Calcium ATPase, transmembrane domain M0.0125Inherited
Metal cation-transporting ATPase, ATP-binding domain N0.0125Inherited
5' to 3' exonuclease, C-terminal subdomain0.02057Inherited
F1F0 ATP synthase subunit C0.02057Inherited
DNA repair protein MutS, domain III0.02057Inherited
DEATH domain0.02757Inherited
Calcium ATPase, transduction domain A0.02772Inherited
SH3-domain0.04629Inherited
PH domain-like0.06062Inherited
ARM repeat0.06173Inherited
SET domain0.0624Inherited
Activating enzymes of the ubiquitin-like proteins0.0653Inherited
Sec1/munc18-like (SM) proteins0.06811Inherited
Hect, E3 ligase catalytic domain0.06811Inherited
HLH, helix-loop-helix DNA-binding domain0.1082Inherited
Lamin A/C globular tail domain0.1202Inherited
PIN domain-like0.14Inherited
Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor0.14Inherited
SNARE-like0.1572Inherited
POZ domain0.1741Inherited
Saposin0.214Inherited
Intermediate filament protein, coiled coil region0.2293Inherited
"Winged helix" DNA-binding domain0.2828Inherited
Nucleic acid-binding proteins0.3931Inherited
Chromo domain-like0.4241Inherited
Histone-fold0.4611Inherited
WD40 repeat-like0.4803Inherited
Metallo-dependent phosphatases0.5894Inherited
PLP-dependent transferases0.6043Inherited
S-adenosyl-L-methionine-dependent methyltransferases0.663Inherited


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Family

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SCOP termFDR (all)Annotation (direct or inherited)
N-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
PX domain0Direct
Group II chaperonin (CCT, TRIC), intermediate domain0Direct
Arginine methyltransferase0Direct
Phoshoinositide 3-kinase (PI3K) helical domain0Direct
Integrin domains0Direct
C-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
Cullin repeat0Direct
SCF ubiquitin ligase complex WHB domain0Direct
RNA-polymerase beta0Direct
Protein prenyltransferases0Direct
DLC0Direct
Myotubularin-like phosphatases0Direct
FYVE, a phosphatidylinositol-3-phosphate binding domain0.000000000000001256Direct
Calpain large subunit, middle domain (domain III)0.000001341Direct
RecA protein-like (ATPase-domain)0.000001911Direct
Skp1 dimerisation domain-like0.000008685Direct
Ephrin ectodomain0.0001896Direct
Caspase catalytic domain0.0001896Direct
Group II chaperonin (CCT, TRIC), apical domain0.0002335Direct
Calpain large subunit, catalytic domain (domain II)0.0003022Direct
Group II chaperonin (CCT, TRIC), ATPase domain0.0007069Direct
Cullin homology domain0.0007069Direct
Phoshoinositide 3-kinase (PI3K), catalytic domain0.001409Inherited
BTB/POZ domain0.005034Inherited
Sm motif of small nuclear ribonucleoproteins, SNRNP0.009989Inherited
G proteins0.01016Inherited
BAR domain0.01873Inherited
F1F0 ATP synthase subunit C0.01873Inherited
DNA repair protein MutS, domain III0.01873Inherited
5' to 3' exonuclease, C-terminal subdomain0.01873Inherited
5' to 3' exonuclease catalytic domain0.01873Inherited
Cold shock DNA-binding domain-like0.02251Inherited
Calcium ATPase, transduction domain A0.02661Inherited
Protein kinases, catalytic subunit0.04438Inherited
SH3-domain0.04852Inherited
Histone lysine methyltransferases0.05065Inherited
Clathrin adaptor core protein0.06194Inherited
Ubiquitin activating enzymes (UBA)0.06376Inherited
Sec1/munc18-like (SM) proteins0.06376Inherited
Hect, E3 ligase catalytic domain0.06376Inherited
Phosphotyrosine-binding domain (PTB)0.09885Inherited
HLH, helix-loop-helix DNA-binding domain0.1091Inherited
Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor0.1335Inherited
Intermediate filament protein, coiled coil region0.2219Inherited
Translational machinery components0.2219Inherited
Armadillo repeat0.2633Inherited
Nucleosome core histones0.4497Inherited
Proteasome subunits0.5924Inherited
ABC transporter ATPase domain-like0.7508Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
Subdomain of clathrin and coatomer appendage domain0Direct
PX domain0Direct
VPS9 domain0Direct
Clathrin adaptor appendage domain0Direct
RBP11-like subunits of RNA polymerase0Direct
N-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
DLC0Direct
C-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
Calpain large subunit, middle domain (domain III)0.0000003908Direct
beta and beta-prime subunits of DNA dependent RNA-polymerase0.0000006651Direct
Cullin repeat-like0.000001604Direct
Skp1 dimerisation domain-like0.00000667Direct
Terpenoid cyclases/Protein prenyltransferases0.00009737Direct
Integrin domains0.00009737Direct
FYVE/PHD zinc finger0.0002957Direct
Cupredoxins0.0004317Direct
Tubby C-terminal domain-like0.0004317Direct
Caspase-like0.0004317Direct
Cullin homology domain0.0006511Direct
GroEL apical domain-like0.00127Inherited
GroEL-intermediate domain like0.003481Inherited
GroEL equatorial domain-like0.003481Inherited
Sm-like ribonucleoproteins0.004303Inherited
ENTH/VHS domain0.004303Inherited
Protein kinase-like (PK-like)0.006513Inherited
BAR/IMD domain-like0.01035Inherited
Calcium ATPase, transmembrane domain M0.01079Inherited
Metal cation-transporting ATPase, ATP-binding domain N0.01079Inherited
FAD/NAD-linked reductases, dimerisation (C-terminal) domain0.01792Inherited
F1F0 ATP synthase subunit C0.01792Inherited
5' to 3' exonuclease, C-terminal subdomain0.01792Inherited
DNA repair protein MutS, domain III0.01792Inherited
DEATH domain0.02416Inherited
Calcium ATPase, transduction domain A0.02429Inherited
SH3-domain0.041Inherited
PH domain-like0.05398Inherited
ARM repeat0.055Inherited
SET domain0.05563Inherited
Activating enzymes of the ubiquitin-like proteins0.0583Inherited
Hect, E3 ligase catalytic domain0.06088Inherited
Sec1/munc18-like (SM) proteins0.06088Inherited
HLH, helix-loop-helix DNA-binding domain0.09787Inherited
Lamin A/C globular tail domain0.1091Inherited
PIN domain-like0.1278Inherited
Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor0.1278Inherited
SNARE-like0.1439Inherited
POZ domain0.1598Inherited
Saposin0.1977Inherited
Intermediate filament protein, coiled coil region0.2123Inherited
"Winged helix" DNA-binding domain0.2641Inherited
Nucleic acid-binding proteins0.3725Inherited
Chromo domain-like0.4027Inherited
Histone-fold0.4396Inherited
WD40 repeat-like0.4585Inherited
Metallo-dependent phosphatases0.567Inherited
PLP-dependent transferases0.582Inherited
S-adenosyl-L-methionine-dependent methyltransferases0.6419Inherited

(show details)
Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
75632,46785
  • 75632 - Cullin homology domain
  • 46785 - "Winged helix" DNA-binding domain
  • 0Direct
    49562,48371
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 48371 - ARM repeat
  • 0Direct
    49348,55711
  • 49348 - Clathrin adaptor appendage domain
  • 55711 - Subdomain of clathrin and coatomer appendage domain
  • 0Direct
    74788,75632
  • 74788 - Cullin repeat-like
  • 75632 - Cullin homology domain
  • 0Direct
    52540,47917
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 47917 - C-terminal domain of alpha and beta subunits of F1 ATP synthase
  • 0Direct
    54001,49758
  • 54001 - Cysteine proteinases
  • 49758 - Calpain large subunit, middle domain (domain III)
  • 0.00000005366Direct
    48371,56112
  • 48371 - ARM repeat
  • 56112 - Protein kinase-like (PK-like)
  • 0.000008117Direct
    54695,81382
  • 54695 - POZ domain
  • 81382 - Skp1 dimerisation domain-like
  • 0.00001787Direct
    81333,81333
  • 81333 - F1F0 ATP synthase subunit C
  • 81333 - F1F0 ATP synthase subunit C
  • 0.00009737Direct
    54849,52029
  • 54849 - GroEL-intermediate domain like
  • 52029 - GroEL apical domain-like
  • 0.003481Inherited
    48592,54849
  • 48592 - GroEL equatorial domain-like
  • 54849 - GroEL-intermediate domain like
  • 0.003481Inherited
    81660,56784
  • 81660 - Metal cation-transporting ATPase, ATP-binding domain N
  • 56784 - HAD-like
  • 0.01079Inherited
    48334,52540
  • 48334 - DNA repair protein MutS, domain III
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.01792Inherited
    51905,55424
  • 51905 - FAD/NAD(P)-binding domain
  • 55424 - FAD/NAD-linked reductases, dimerisation (C-terminal) domain
  • 0.01792Inherited
    57424,57424
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 0.1278Inherited
    57196,57196
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.3562Inherited

    (show details)
    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    49562,48371,56112
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 48371 - ARM repeat
  • 56112 - Protein kinase-like (PK-like)
  • 0Direct
    74788,75632,46785
  • 74788 - Cullin repeat-like
  • 75632 - Cullin homology domain
  • 46785 - "Winged helix" DNA-binding domain
  • 0Direct
    48592,54849,52029
  • 48592 - GroEL equatorial domain-like
  • 54849 - GroEL-intermediate domain like
  • 52029 - GroEL apical domain-like
  • 0.003481Inherited
    81660,56784,81665
  • 81660 - Metal cation-transporting ATPase, ATP-binding domain N
  • 56784 - HAD-like
  • 81665 - Calcium ATPase, transmembrane domain M
  • 0.01079Inherited
    57424,57424,57424
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 0.1278Inherited


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
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