SUPERFAMILY 1.75 HMM library and genome assignments server

Superfamily is undergoing a server migration - you are now browsing on the new server. Please contact us if you experience any problems.

Worm Phenotype (WP): apoptosis variant

(show info)

Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Root: WP Hierarchy (worm phenotype from Wormbase Release WS226)

Shortest distance to current term (+ for parents, - for children) WP term [WP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + + + 5:   Variant [WBPhenotype:0000886] <4>
+ + + + 4:   physiology variant [WBPhenotype:0000519] <7>(487|558) (487|240|64)
+ + + 3:   blast cell physiology variant [WBPhenotype:0000985] <26>(152|154) (153|66|17)
+ + + 3:   cell physiology variant [WBPhenotype:0000536] <26>(152|154) (153|66|17)
+ + 2:   cell death variant [WBPhenotype:0000729] <3>(56|50) (57|16|5)
+ 1:   programmed cell death variant [WBPhenotype:0001172] <3>(54|47) (55|15|5)
0:   apoptosis variant [WBPhenotype:0000730] <13>(50|43) (50|12|5)
- 1:   engulfment variant [WBPhenotype:0000885] <4>(1|1) (1|0|0)
- 1:   apoptosis increased [WBPhenotype:0000183] <2>(7|8) (7|3|1)
- 1:   apoptosis reduced [WBPhenotype:0000182] <2>(3|4) (3|0|0)
- 1:   cell corpse number variant [WBPhenotype:0000590] <2>(29|29) (30|10|5)
- 1:   cell death sexually dimorphic variant [WBPhenotype:0001218] <2>(0|0) (0|0|0)
- 1:   mutagen induced apoptosis variant [WBPhenotype:0002152] <2>(4|1) (4|0|0)
- 1:   apoptosis protracted [WBPhenotype:0000185] <1>(2|2) (2|0|0)
- 1:   apoptotic DNA degradation defective [WBPhenotype:0002201](0|0) (0|0|0)
- 1:   apoptotic arrest [WBPhenotype:0000244](0|0) (0|0|0)
- 1:   apoptotic cell shedding variant [WBPhenotype:0002180](0|0) (0|0|0)
- 1:   cell corpse degradation variant [WBPhenotype:0010004](2|2) (2|0|0)
- 1:   corpse morphology variant [WBPhenotype:0002203](0|0) (0|0|0)
- 1:   starvation induced apoptosis variant [WBPhenotype:0002184](0|0) (0|0|0)


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Superfamily

(show details)
SCOP termFDR (all)Annotation (direct or inherited)
RBP11-like subunits of RNA polymerase0Direct
C-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
Clathrin adaptor appendage domain0Direct
DLC0Direct
N-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
VPS9 domain0Direct
PX domain0Direct
Subdomain of clathrin and coatomer appendage domain0Direct
Skp1 dimerisation domain-like0.00000000000002174Direct
Cullin homology domain0.00000003246Direct
GroEL apical domain-like0.00000008956Direct
PH domain-like0.0000001932Direct
beta and beta-prime subunits of DNA dependent RNA-polymerase0.0000004448Direct
GroEL equatorial domain-like0.0000009792Direct
Cullin repeat-like0.0000009792Direct
GroEL-intermediate domain like0.0000009792Direct
ENTH/VHS domain0.00000431Direct
Histone-fold0.000007371Direct
Nucleic acid-binding proteins0.00004336Direct
SH3-domain0.00004336Direct
Sm-like ribonucleoproteins0.00004565Direct
"Winged helix" DNA-binding domain0.00004747Direct
5' to 3' exonuclease, C-terminal subdomain0.00007897Direct
Integrin domains0.00007897Direct
BAR/IMD domain-like0.0001938Direct
Activating enzymes of the ubiquitin-like proteins0.0002492Direct
Tubby C-terminal domain-like0.0003518Direct
Cupredoxins0.0003518Direct
DEATH domain0.0005114Direct
SNARE-like0.0006572Direct
Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor0.0009456Direct
Sec1/munc18-like (SM) proteins0.0009456Direct
Metal cation-transporting ATPase, ATP-binding domain N0.001178Inherited
Lamin A/C globular tail domain0.001559Inherited
Calcium ATPase, transmembrane domain M0.001592Inherited
HLH, helix-loop-helix DNA-binding domain0.002877Inherited
PIN domain-like0.003624Inherited
Calcium ATPase, transduction domain A0.005141Inherited
Hect, E3 ligase catalytic domain0.005896Inherited
Intermediate filament protein, coiled coil region0.0129Inherited
POZ domain0.08859Inherited
Chromo domain-like0.09224Inherited
Saposin0.1676Inherited
ARM repeat0.1684Inherited
PLP-dependent transferases0.4847Inherited
S-adenosyl-L-methionine-dependent methyltransferases0.5453Inherited
SET domain0.7735Inherited
FYVE/PHD zinc finger0.8457Inherited
Metallo-dependent phosphatases0.8815Inherited
Protein kinase-like (PK-like)0.9901Inherited


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Family

(show details)
SCOP termFDR (all)Annotation (direct or inherited)
N-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
PX domain0Direct
Group II chaperonin (CCT, TRIC), intermediate domain0Direct
Arginine methyltransferase0Direct
Phoshoinositide 3-kinase (PI3K) helical domain0Direct
Integrin domains0Direct
C-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
Cullin repeat0Direct
SCF ubiquitin ligase complex WHB domain0Direct
RNA-polymerase beta0Direct
DLC0Direct
Myotubularin-like phosphatases0Direct
FYVE, a phosphatidylinositol-3-phosphate binding domain3.143e-16Direct
Skp1 dimerisation domain-like0.00000000000008118Direct
Group II chaperonin (CCT, TRIC), apical domain0.0000000641Direct
Cullin homology domain0.00000008971Direct
Group II chaperonin (CCT, TRIC), ATPase domain0.0000006504Direct
RecA protein-like (ATPase-domain)0.000001019Direct
Nucleosome core histones0.00002657Direct
BTB/POZ domain0.00004635Direct
G proteins0.00005751Direct
Phoshoinositide 3-kinase (PI3K), catalytic domain0.00006274Direct
Ephrin ectodomain0.0001255Direct
5' to 3' exonuclease, C-terminal subdomain0.0001255Direct
5' to 3' exonuclease catalytic domain0.0001255Direct
Cold shock DNA-binding domain-like0.0001538Direct
Clathrin adaptor core protein0.000192Direct
SH3-domain0.0002828Direct
Ubiquitin activating enzymes (UBA)0.000556Direct
BAR domain0.000556Direct
Phosphotyrosine-binding domain (PTB)0.0008678Direct
Sm motif of small nuclear ribonucleoproteins, SNRNP0.0008678Direct
Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor0.001492Inherited
Sec1/munc18-like (SM) proteins0.001492Inherited
Armadillo repeat0.004419Inherited
Translational machinery components0.005674Inherited
HLH, helix-loop-helix DNA-binding domain0.007956Inherited
Hect, E3 ligase catalytic domain0.009224Inherited
Proteasome subunits0.009226Inherited
Calcium ATPase, transduction domain A0.01026Inherited
Intermediate filament protein, coiled coil region0.02005Inherited
Histone lysine methyltransferases0.8112Inherited
Protein kinases, catalytic subunit0.9991Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
Plot tree as:   Download Newick format tree:
(show help)

Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

(show details)
Supra-domain (Single) FDR (all) Annotation (direct or inherited)
Subdomain of clathrin and coatomer appendage domain0Direct
PX domain0Direct
VPS9 domain0Direct
Clathrin adaptor appendage domain0Direct
RBP11-like subunits of RNA polymerase0Direct
N-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
DLC0Direct
C-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
Skp1 dimerisation domain-like0.00000000000001718Direct
Cullin homology domain0.00000002614Direct
GroEL apical domain-like0.00000007228Direct
PH domain-like0.0000001562Direct
beta and beta-prime subunits of DNA dependent RNA-polymerase0.0000003605Direct
GroEL-intermediate domain like0.0000007967Direct
GroEL equatorial domain-like0.0000007967Direct
Cullin repeat-like0.0000007967Direct
ENTH/VHS domain0.000003524Direct
Histone-fold0.000006029Direct
Nucleic acid-binding proteins0.00003569Direct
SH3-domain0.00003569Direct
Sm-like ribonucleoproteins0.0000376Direct
"Winged helix" DNA-binding domain0.0000391Direct
5' to 3' exonuclease, C-terminal subdomain0.00006512Direct
Integrin domains0.00006512Direct
BAR/IMD domain-like0.0001603Direct
Activating enzymes of the ubiquitin-like proteins0.0002064Direct
Cupredoxins0.0002918Direct
Tubby C-terminal domain-like0.0002918Direct
DEATH domain0.0004252Direct
SNARE-like0.0005483Direct
Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor0.0007921Direct
Sec1/munc18-like (SM) proteins0.0007921Direct
Metal cation-transporting ATPase, ATP-binding domain N0.000987Direct
Lamin A/C globular tail domain0.001311Inherited
Calcium ATPase, transmembrane domain M0.001339Inherited
HLH, helix-loop-helix DNA-binding domain0.002436Inherited
PIN domain-like0.003075Inherited
Calcium ATPase, transduction domain A0.004381Inherited
Hect, E3 ligase catalytic domain0.005032Inherited
Intermediate filament protein, coiled coil region0.01114Inherited
POZ domain0.07972Inherited
Chromo domain-like0.08307Inherited
Saposin0.1537Inherited
ARM repeat0.1545Inherited
PLP-dependent transferases0.4632Inherited
S-adenosyl-L-methionine-dependent methyltransferases0.5234Inherited
SET domain0.754Inherited
FYVE/PHD zinc finger0.8283Inherited
Metallo-dependent phosphatases0.8657Inherited
Protein kinase-like (PK-like)0.9794Inherited

(show details)
Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
75632,46785
  • 75632 - Cullin homology domain
  • 46785 - "Winged helix" DNA-binding domain
  • 0Direct
    49562,48371
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 48371 - ARM repeat
  • 0Direct
    49348,55711
  • 49348 - Clathrin adaptor appendage domain
  • 55711 - Subdomain of clathrin and coatomer appendage domain
  • 0Direct
    74788,75632
  • 74788 - Cullin repeat-like
  • 75632 - Cullin homology domain
  • 0Direct
    52540,47917
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 47917 - C-terminal domain of alpha and beta subunits of F1 ATP synthase
  • 0Direct
    54695,81382
  • 54695 - POZ domain
  • 81382 - Skp1 dimerisation domain-like
  • 0.0000000000000497Direct
    54849,52029
  • 54849 - GroEL-intermediate domain like
  • 52029 - GroEL apical domain-like
  • 0.0000007967Direct
    48592,54849
  • 48592 - GroEL equatorial domain-like
  • 54849 - GroEL-intermediate domain like
  • 0.0000007967Direct
    48371,56112
  • 48371 - ARM repeat
  • 56112 - Protein kinase-like (PK-like)
  • 0.0002918Direct
    81660,56784
  • 81660 - Metal cation-transporting ATPase, ATP-binding domain N
  • 56784 - HAD-like
  • 0.000987Direct
    57196,57196
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.00718Inherited
    57424,57424
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 0.02666Inherited

    (show details)
    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    49562,48371,56112
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 48371 - ARM repeat
  • 56112 - Protein kinase-like (PK-like)
  • 0Direct
    74788,75632,46785
  • 74788 - Cullin repeat-like
  • 75632 - Cullin homology domain
  • 46785 - "Winged helix" DNA-binding domain
  • 0Direct
    48592,54849,52029
  • 48592 - GroEL equatorial domain-like
  • 54849 - GroEL-intermediate domain like
  • 52029 - GroEL apical domain-like
  • 0.0000007967Direct
    81660,56784,81665
  • 81660 - Metal cation-transporting ATPase, ATP-binding domain N
  • 56784 - HAD-like
  • 81665 - Calcium ATPase, transmembrane domain M
  • 0.0007122Direct
    57424,57424,57424
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 0.01114Inherited


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
    Plot tree as:   Download Newick format tree:
    (show help)