SUPERFAMILY 1.75 HMM library and genome assignments server

Superfamily is undergoing a server migration - you are now browsing on the new server. Please contact us if you experience any problems.

Worm Phenotype (WP): level of transgene expression variant

(show info)

Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Root: WP Hierarchy (worm phenotype from Wormbase Release WS226)

Shortest distance to current term (+ for parents, - for children) WP term [WP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + + + + + 7:   Variant [WBPhenotype:0000886] <4>
+ + + + + + 6:   physiology variant [WBPhenotype:0000519] <7>(487|558) (487|240|64)
+ + + + + 5:   organism physiology variant [WBPhenotype:0000576] <10>(355|415) (355|191|56)
+ + + + 4:   organism homeostasis metabolism variant [WBPhenotype:0000577] <17>(346|406) (348|189|55)
+ + + 3:   organism metabolism processing variant [WBPhenotype:0000027] <25>(171|182) (175|80|24)
+ + 2:   gene expression variant [WBPhenotype:0000717] <10>(122|134) (127|61|19)
+ 1:   transgene expression variant [WBPhenotype:0000306] <3>(84|95) (88|41|13)
0:   level of transgene expression variant [WBPhenotype:0000962] <2>(35|44) (38|13|6)
- 1:   transgene expression reduced [WBPhenotype:0001278] <3>(11|14) (11|2|2)
- 1:   transgene expression increased [WBPhenotype:0001236](15|22) (18|9|4)


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Superfamily

(show details)
SCOP termFDR (all)Annotation (direct or inherited)
TK C-terminal domain-like0Direct
GroEL equatorial domain-like0Direct
HSP90 C-terminal domain0Direct
Ribosomal protein L10Direct
F1F0 ATP synthase subunit C0Direct
FF domain0Direct
Heme-dependent catalase-like0Direct
Cytochrome c0Direct
GroEL-intermediate domain like0Direct
Epsilon subunit of mitochondrial F1F0-ATP synthase0Direct
ValRS/IleRS/LeuRS editing domain0Direct
14-3-3 protein0Direct
GroEL apical domain-like0.00000001615Direct
Homeodomain-like0.00000005442Direct
Glucocorticoid receptor-like (DNA-binding domain)0.0000001816Direct
Saposin0.000005957Direct
beta and beta-prime subunits of DNA dependent RNA-polymerase0.00003133Direct
Leucine zipper domain0.00004542Direct
Single hybrid motif0.00007064Direct
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases0.00007064Direct
Zn-binding ribosomal proteins0.0001811Direct
ClpP/crotonase0.0001877Direct
Nuclear receptor ligand-binding domain0.0006336Direct
Cdc48 domain 2-like0.001265Inherited
ADC-like0.001265Inherited
Tubby C-terminal domain-like0.005084Inherited
S15/NS1 RNA-binding domain0.005084Inherited
Nucleotidylyl transferase0.02768Inherited
SMAD MH1 domain0.06114Inherited
S-adenosylmethionine synthetase0.17Inherited
4Fe-4S ferredoxins0.17Inherited
Frizzled cysteine-rich domain0.17Inherited
PYP-like sensor domain (PAS domain)0.2792Inherited
Class II aaRS ABD-related0.3573Inherited
Heat shock protein 70kD (HSP70), C-terminal subdomain0.6747Inherited


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Family

(show details)
SCOP termFDR (all)Annotation (direct or inherited)
Ribosomal protein L10Direct
a tRNA synthase domain0Direct
Group II chaperonin (CCT, TRIC), intermediate domain0Direct
FF domain0Direct
Branched-chain alpha-keto acid dehydrogenase beta-subunit, C-terminal-domain0Direct
ValRS/IleRS/LeuRS editing domain0Direct
Group II chaperonin (CCT, TRIC), ATPase domain0Direct
Epsilon subunit of mitochondrial F1F0-ATP synthase0Direct
RNA-polymerase beta0Direct
Heat shock protein 90, HSP90, N-terminal domain0Direct
Hsp90 middle domain0Direct
Heme-dependent catalases0Direct
Anticodon-binding domain of Class II aaRS0Direct
F1F0 ATP synthase subunit C0Direct
14-3-3 protein0Direct
HSP90 C-terminal domain0Direct
CAT-like0Direct
Group II chaperonin (CCT, TRIC), apical domain0.000000423Direct
Homeodomain0.000002456Direct
Biotinyl/lipoyl-carrier proteins and domains0.000209Direct
Leucine zipper domain0.0002237Direct
Transforming growth factor (TGF)-beta0.0003786Direct
Cyclin0.0006834Direct
Dual specificity phosphatase-like0.0007273Direct
Proteasome subunits0.0007273Direct
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases0.0008291Direct
Biotin dependent carboxylase carboxyltransferase domain0.00201Inherited
Cdc48 N-terminal domain-like0.00201Inherited
MIF4G domain-like0.00201Inherited
Anticodon-binding domain0.00201Inherited
Cdc48 domain 2-like0.00201Inherited
DEP domain0.008035Inherited
Nuclear receptor0.01594Inherited
SMAD domain0.03256Inherited
Nuclear receptor ligand-binding domain0.05303Inherited
SMAD MH1 domain0.05524Inherited
Class I aminoacyl-tRNA synthetases (RS), catalytic domain0.05768Inherited
Protein kinases, catalytic subunit0.106Inherited
Frizzled cysteine-rich domain0.157Inherited
S-adenosylmethionine synthetase0.157Inherited
RecA protein-like (ATPase-domain)0.2643Inherited
PDI-like0.2643Inherited
PLC-like (P variant)0.5131Inherited
Heat shock protein 70kD (HSP70), C-terminal subdomain0.6645Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
Plot tree as:   Download Newick format tree:
(show help)

Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

(show details)
Supra-domain (Single) FDR (all) Annotation (direct or inherited)
GroEL-intermediate domain like0Direct
TK C-terminal domain-like0Direct
ValRS/IleRS/LeuRS editing domain0Direct
GroEL equatorial domain-like0Direct
14-3-3 protein0Direct
Cytochrome c0Direct
Ribosomal protein L10Direct
F1F0 ATP synthase subunit C0Direct
Heme-dependent catalase-like0Direct
FF domain0Direct
Epsilon subunit of mitochondrial F1F0-ATP synthase0Direct
HSP90 C-terminal domain0Direct
GroEL apical domain-like0.00000001298Direct
Homeodomain-like0.00000004388Direct
Glucocorticoid receptor-like (DNA-binding domain)0.0000001468Direct
Saposin0.00000487Direct
beta and beta-prime subunits of DNA dependent RNA-polymerase0.00002575Direct
Leucine zipper domain0.0000374Direct
Single hybrid motif0.00005821Direct
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases0.00005821Direct
Zn-binding ribosomal proteins0.0001497Direct
ClpP/crotonase0.0001552Direct
Nuclear receptor ligand-binding domain0.0005284Direct
ADC-like0.001061Inherited
Cdc48 domain 2-like0.001061Inherited
S15/NS1 RNA-binding domain0.004331Inherited
Tubby C-terminal domain-like0.004331Inherited
Thiamin diphosphate-binding fold (THDP-binding)0.01016Inherited
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase0.01016Inherited
Nucleotidylyl transferase0.02425Inherited
SMAD MH1 domain0.05445Inherited
4Fe-4S ferredoxins0.156Inherited
S-adenosylmethionine synthetase0.156Inherited
Frizzled cysteine-rich domain0.156Inherited
PYP-like sensor domain (PAS domain)0.2606Inherited
Class II aaRS ABD-related0.337Inherited
Heat shock protein 70kD (HSP70), peptide-binding domain0.6236Inherited
Heat shock protein 70kD (HSP70), C-terminal subdomain0.6538Inherited

(show details)
Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
54849,52029
  • 54849 - GroEL-intermediate domain like
  • 52029 - GroEL apical domain-like
  • 0Direct
    48592,54849
  • 48592 - GroEL equatorial domain-like
  • 54849 - GroEL-intermediate domain like
  • 0Direct
    50677,52374
  • 50677 - ValRS/IleRS/LeuRS editing domain
  • 52374 - Nucleotidylyl transferase
  • 0Direct
    81698,81698
  • 81698 - FF domain
  • 81698 - FF domain
  • 0Direct
    81333,81333
  • 81333 - F1F0 ATP synthase subunit C
  • 81333 - F1F0 ATP synthase subunit C
  • 0Direct
    50692,54585
  • 50692 - ADC-like
  • 54585 - Cdc48 domain 2-like
  • 0Direct
    54585,52540
  • 54585 - Cdc48 domain 2-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    52518,52922
  • 52518 - Thiamin diphosphate-binding fold (THDP-binding)
  • 52922 - TK C-terminal domain-like
  • 0Direct
    50249,55681
  • 50249 - Nucleic acid-binding proteins
  • 55681 - Class II aaRS and biotin synthetases
  • 0.004331Inherited
    55681,52954
  • 55681 - Class II aaRS and biotin synthetases
  • 52954 - Class II aaRS ABD-related
  • 0.156Inherited
    55973,55973
  • 55973 - S-adenosylmethionine synthetase
  • 55973 - S-adenosylmethionine synthetase
  • 0.156Inherited
    100920,100934
  • 100920 - Heat shock protein 70kD (HSP70), peptide-binding domain
  • 100934 - Heat shock protein 70kD (HSP70), C-terminal subdomain
  • 0.6236Inherited
    53067,100920
  • 53067 - Actin-like ATPase domain
  • 100920 - Heat shock protein 70kD (HSP70), peptide-binding domain
  • 0.6236Inherited

    (show details)
    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    50692,54585,52540
  • 50692 - ADC-like
  • 54585 - Cdc48 domain 2-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    54585,52540,52540
  • 54585 - Cdc48 domain 2-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    48592,54849,52029
  • 48592 - GroEL equatorial domain-like
  • 54849 - GroEL-intermediate domain like
  • 52029 - GroEL apical domain-like
  • 0Direct
    55973,55973,55973
  • 55973 - S-adenosylmethionine synthetase
  • 55973 - S-adenosylmethionine synthetase
  • 55973 - S-adenosylmethionine synthetase
  • 0.156Inherited
    53067,53067,100920
  • 53067 - Actin-like ATPase domain
  • 53067 - Actin-like ATPase domain
  • 100920 - Heat shock protein 70kD (HSP70), peptide-binding domain
  • 0.6236Inherited
    53067,100920,100934
  • 53067 - Actin-like ATPase domain
  • 100920 - Heat shock protein 70kD (HSP70), peptide-binding domain
  • 100934 - Heat shock protein 70kD (HSP70), C-terminal subdomain
  • 0.6236Inherited


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
    Plot tree as:   Download Newick format tree:
    (show help)