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Worm Phenotype (WP): blast cell physiology variant

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Root: WP Hierarchy (worm phenotype from Wormbase Release WS226)

Shortest distance to current term (+ for parents, - for children) WP term [WP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + 2:   Variant [WBPhenotype:0000886] <4>
+ 1:   physiology variant [WBPhenotype:0000519] <7>(489|563) (489|241|65)
0:   blast cell physiology variant [WBPhenotype:0000985] <26>(152|154) (153|67|17)
- 1:   cell division variant [WBPhenotype:0000746] <20>(55|57) (55|24|4)
- 1:   cell homeostasis metabolism variant [WBPhenotype:0000585] <12>(65|61) (65|26|11)
- 1:   muscle cell physiology variant [WBPhenotype:0000990] <7>(18|20) (19|12|4)
- 1:   neuron physiology variant [WBPhenotype:0000991] <7>(4|5) (4|1|0)
- 1:   cell secretion variant [WBPhenotype:0000258] <6>(7|7) (7|0|0)
- 1:   cell cycle variant [WBPhenotype:0000740] <5>(8|10) (8|4|1)
- 1:   calcium mediated signaling variant [WBPhenotype:0002170] <4>(0|0) (0|0|0)
- 1:   germ cell physiology variant [WBPhenotype:0000987] <4>(7|5) (7|0|0)
- 1:   nuclear positioning variant [WBPhenotype:0000511] <4>(12|14) (13|5|1)
- 1:   cell death variant [WBPhenotype:0000729] <3>(57|51) (58|17|5)
- 1:   cell membrane physiology variant [WBPhenotype:0001965] <3>(0|0) (0|0|0)
- 1:   membrane trafficking variant [WBPhenotype:0001833] <3>(4|3) (4|1|0)
- 1:   oocyte physiology variant [WBPhenotype:0001424] <3>(14|14) (15|7|1)
- 1:   endocytic transport variant [WBPhenotype:0001421] <2>(28|26) (29|11|2)
- 1:   epithelial cell physiology variant [WBPhenotype:0000986] <2>(3|3) (3|2|1)
- 1:   vesicle trafficking variant [WBPhenotype:0001752] <2>(1|0) (1|0|0)
- 1:   coelomocyte physiology variant [WBPhenotype:0001423] <1>(7|7) (7|2|0)
- 1:   embryonic cell physiology variant [WBPhenotype:0000763] <1>(13|17) (13|7|0)
- 1:   lysosome homeostasis deficient [WBPhenotype:0001784] <1>(0|0) (0|0|0)
- 1:   lysosome organization biogenesis variant [WBPhenotype:0001430] <1>(3|3) (3|2|2)
- 1:   nuclear division variant [WBPhenotype:0000504] <1>(7|8) (7|4|2)
- 1:   plasma membrane composition variant [WBPhenotype:0002177] <1>(4|1) (4|1|1)
- 1:   cell growth variant [WBPhenotype:0010001](0|0) (0|0|0)
- 1:   gland cell physiology variant [WBPhenotype:0000988](0|0) (0|0|0)
- 1:   marginal cell physiology variant [WBPhenotype:0000989](0|0) (0|0|0)
- 1:   peroxisome physiology variant [WBPhenotype:0001264](0|0) (0|0|0)


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Superfamily

(show details)
SCOP termFDR (all)Annotation (direct or inherited)
Lipovitellin-phosvitin complex; beta-sheet shell regions0Direct
Ribosomal protein S100Direct
P-loop containing nucleoside triphosphate hydrolases0Direct
ValRS/IleRS/LeuRS editing domain0Direct
DNA repair protein MutS, domain III0Direct
Restriction endonuclease-like0Direct
C-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
Smc hinge domain0Direct
Lipovitellin-phosvitin complex, superhelical domain0Direct
N-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
Lesion bypass DNA polymerase (Y-family), little finger domain0Direct
Cullin homology domain0Direct
Profilin (actin-binding protein)0Direct
Ribosomal protein L10Direct
RBP11-like subunits of RNA polymerase0Direct
LEM domain0Direct
ARM repeat0Direct
The spindle assembly checkpoint protein mad20Direct
Clathrin adaptor appendage domain0Direct
Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor0Direct
HSP90 C-terminal domain0Direct
Ribosomal protein L10-like0Direct
Zn-finger domain of Sec23/240Direct
VPS9 domain0Direct
Helical domain of Sec23/240Direct
PX domain0Direct
DNA ligase/mRNA capping enzyme, catalytic domain0Direct
14-3-3 protein0Direct
C-terminal, gelsolin-like domain of Sec23/240Direct
Subdomain of clathrin and coatomer appendage domain0Direct
5' to 3' exonuclease, C-terminal subdomain0Direct
Sec7 domain0Direct
DLC0Direct
Histone-fold8.891e-16Direct
Nicotinic receptor ligand binding domain-like0.0000000000009126Direct
Nucleic acid-binding proteins0.000000000002936Direct
Neurotransmitter-gated ion-channel transmembrane pore0.0000000000178Direct
"Winged helix" DNA-binding domain0.00000000002151Direct
Skp1 dimerisation domain-like0.00000000009069Direct
PH domain-like0.0000000002213Direct
WD40 repeat-like0.000000004651Direct
FYVE/PHD zinc finger0.0000004662Direct
GroEL apical domain-like0.000004176Direct
Translation proteins SH3-like domain0.000009638Direct
N-terminal nucleophile aminohydrolases (Ntn hydrolases)0.00001099Direct
SNARE-like0.00001413Direct
GroEL-intermediate domain like0.0000158Direct
t-snare proteins0.0000158Direct
GroEL equatorial domain-like0.0000158Direct
C2 domain (Calcium/lipid-binding domain, CaLB)0.00001611Direct
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases0.00003346Direct
Translation proteins0.00003411Direct
SH3-domain0.00004574Direct
Activating enzymes of the ubiquitin-like proteins0.00005934Direct
Calponin-homology domain, CH-domain0.0001167Direct
ENTH/VHS domain0.0001579Direct
Actin-like ATPase domain0.0001746Direct
Cyclin-like0.0002769Direct
HLH, helix-loop-helix DNA-binding domain0.0002897Direct
Tubulin C-terminal domain-like0.0003849Direct
Lamin A/C globular tail domain0.0004576Direct
Spectrin repeat0.0004576Direct
Ribosomal protein S5 domain 2-like0.0006128Direct
Sec1/munc18-like (SM) proteins0.0008113Direct
Clc chloride channel0.0008113Direct
beta and beta-prime subunits of DNA dependent RNA-polymerase0.0008113Direct
Tubulin nucleotide-binding domain-like0.001019Inherited
DNA/RNA polymerases0.00119Inherited
PIN domain-like0.001258Inherited
Prefoldin0.001258Inherited
Calpain large subunit, middle domain (domain III)0.001258Inherited
Class II aaRS ABD-related0.001258Inherited
Nucleotidylyl transferase0.001436Inherited
RNA-binding domain, RBD0.002144Inherited
CAD & PB1 domains0.002936Inherited
Ribosomal proteins S24e, L23 and L15e0.002936Inherited
F1F0 ATP synthase subunit C0.002936Inherited
Frizzled cysteine-rich domain0.002936Inherited
Class II aaRS and biotin synthetases0.003129Inherited
Intermediate filament protein, coiled coil region0.003705Inherited
DBL homology domain (DH-domain)0.004021Inherited
Sm-like ribonucleoproteins0.004021Inherited
EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain0.004081Inherited
DEATH domain0.004081Inherited
L30e-like0.004081Inherited
Cullin repeat-like0.004081Inherited
Growth factor receptor domain0.005021Inherited
Metal cation-transporting ATPase, ATP-binding domain N0.005363Inherited
Protein kinase-like (PK-like)0.005624Inherited
Ubiquitin-like0.006824Inherited
GTPase activation domain, GAP0.007692Inherited
TPR-like0.007707Inherited
BAR/IMD domain-like0.007721Inherited
Calcium ATPase, transmembrane domain M0.008729Inherited
Hedgehog/intein (Hint) domain0.009848Inherited
SET domain0.01008Inherited
Cu,Zn superoxide dismutase-like0.01036Inherited
Integrin domains0.01036Inherited
Terpenoid cyclases/Protein prenyltransferases0.01036Inherited
Cdc48 domain 2-like0.01036Inherited
beta-sandwich domain of Sec23/240.01036Inherited
post-AAA+ oligomerization domain-like0.01036Inherited
BEACH domain0.01036Inherited
ADC-like0.01036Inherited
Calcium ATPase, transduction domain A0.01151Inherited
Translational machinery components0.01233Inherited
Di-copper centre-containing domain0.01233Inherited
FAD/NAD-linked reductases, dimerisation (C-terminal) domain0.01233Inherited
Quinoprotein alcohol dehydrogenase-like0.02368Inherited
Hect, E3 ligase catalytic domain0.02507Inherited
cAMP-binding domain-like0.02643Inherited
YWTD domain0.03107Inherited
Invertebrate chitin-binding proteins0.0349Inherited
Chromo domain-like0.03516Inherited
S15/NS1 RNA-binding domain0.03637Inherited
Tubby C-terminal domain-like0.03637Inherited
Cupredoxins0.03637Inherited
Caspase-like0.03637Inherited
Nucleotide-diphospho-sugar transferases0.05531Inherited
PLC-like phosphodiesterases0.05611Inherited
Second domain of FERM0.08814Inherited
Myosin rod fragments0.1014Inherited
Cysteine-rich domain0.1075Inherited
PDZ domain-like0.118Inherited
HAD-like0.1181Inherited
Homeodomain-like0.1191Inherited
FKBP-like0.1458Inherited
BRCT domain0.1875Inherited
CCCH zinc finger0.2157Inherited
p53-like transcription factors0.2543Inherited
UBC-like0.2628Inherited
SH2 domain0.2734Inherited
Multidrug efflux transporter AcrB transmembrane domain0.2784Inherited
CBS-domain pair0.3208Inherited
Cysteine proteinases0.4276Inherited
Transducin (alpha subunit), insertion domain0.4631Inherited
PLP-dependent transferases0.5106Inherited
HSP20-like chaperones0.5151Inherited
E set domains0.5326Inherited
Clavaminate synthase-like0.6139Inherited
Immunoglobulin0.6326Inherited
Lipocalins0.6608Inherited
ABC transporter transmembrane region0.6698Inherited
RING/U-box0.7775Inherited
EF-hand0.7842Inherited
POZ domain0.8695Inherited
S-adenosyl-L-methionine-dependent methyltransferases0.9355Inherited
(Phosphotyrosine protein) phosphatases II0.9859Inherited
Voltage-gated potassium channels0.9979Inherited
Metallo-dependent phosphatases1Inherited
Thioredoxin-like1Inherited
Saposin1Inherited


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Family

(show details)
SCOP termFDR (all)Annotation (direct or inherited)
Phoshoinositide 3-kinase (PI3K), catalytic domain0Direct
DNA replication initiator (cdc21/cdc54) N-terminal domain0Direct
ValRS/IleRS/LeuRS editing domain0Direct
Myotubularin-like phosphatases0Direct
N-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
DNA gyrase/MutL, second domain0Direct
Integrin domains0Direct
RNA-polymerase beta0Direct
L30e/L7ae ribosomal proteins0Direct
Lesion bypass DNA polymerase (Y-family), little finger domain0Direct
5' to 3' exonuclease, C-terminal subdomain0Direct
C-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
Clathrin coat assembly domain0Direct
Ribosomal protein L10Direct
Cullin repeat0Direct
5' to 3' exonuclease catalytic domain0Direct
Ubiquitin activating enzymes (UBA)0Direct
Lesion bypass DNA polymerase (Y-family), catalytic domain0Direct
Clathrin adaptor core protein0Direct
Acyl-carrier protein (ACP)0Direct
Arginine methyltransferase0Direct
Ribosomal protein S100Direct
DLC0Direct
14-3-3 protein0Direct
Protein prenyltransferases0Direct
Cullin homology domain0Direct
Inositol polyphosphate 5-phosphatase (IPP5)0Direct
LEM domain0Direct
Cell cycle transcription factor e2f-dp0Direct
SCF ubiquitin ligase complex WHB domain0Direct
DEATH domain, DD0Direct
Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor0Direct
PX domain0Direct
XPF/Rad1/Mus81 nuclease0Direct
Trunk domain of Sec23/240Direct
Phoshoinositide 3-kinase (PI3K) helical domain0Direct
Sec7 domain0Direct
Lipovitellin-phosvitin complex; beta-sheet shell regions0Direct
Zn-finger domain of Sec23/240Direct
Helical domain of Sec23/240Direct
Heat shock protein 90, HSP90, N-terminal domain0Direct
C-terminal, gelsolin-like domain of Sec23/240Direct
HSP90 C-terminal domain0Direct
Group II chaperonin (CCT, TRIC), intermediate domain0Direct
Hsp90 middle domain0Direct
Profilin (actin-binding protein)0Direct
beta-sandwich domain of Sec23/240Direct
Proteasome subunits0Direct
DNA repair protein MutS, domain III0Direct
Lipovitellin-phosvitin complex, superhelical domain0Direct
Mammalian PLC0Direct
Smc hinge domain0Direct
Nucleosome core histones0.00000000000002425Direct
Skp1 dimerisation domain-like0.0000000001215Direct
Nicotinic receptor ligand binding domain-like0.0000000001912Direct
Neurotransmitter-gated ion-channel transmembrane pore0.0000000008748Direct
FYVE, a phosphatidylinositol-3-phosphate binding domain0.0000000456Direct
Actin/HSP700.000002867Direct
Extended AAA-ATPase domain0.000003375Direct
Pleckstrin-homology domain (PH domain)0.000003921Direct
WD40-repeat0.000004442Direct
Armadillo repeat0.00004188Direct
Group II chaperonin (CCT, TRIC), apical domain0.00005216Direct
t-snare proteins0.00005216Direct
PLC-like (P variant)0.0001231Direct
Translational machinery components0.0001661Direct
Group II chaperonin (CCT, TRIC), ATPase domain0.0001661Direct
Phosphotyrosine-binding domain (PTB)0.0001883Direct
G proteins0.0002728Direct
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases0.000357Direct
Pumilio repeat0.000357Direct
Class I aminoacyl-tRNA synthetases (RS), catalytic domain0.0006728Direct
Cyclin0.0006728Direct
Motor proteins0.0008515Direct
Calponin-homology domain, CH-domain0.0008881Direct
SH3-domain0.0009881Direct
Cold shock DNA-binding domain-like0.001256Inherited
Tubulin, C-terminal domain0.001565Inherited
Sec1/munc18-like (SM) proteins0.001653Inherited
RecA protein-like (ATPase-domain)0.001653Inherited
Clc chloride channel0.001653Inherited
HLH, helix-loop-helix DNA-binding domain0.00252Inherited
Calpain large subunit, middle domain (domain III)0.002873Inherited
Tandem AAA-ATPase domain0.002997Inherited
Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain0.003286Inherited
Histone lysine methyltransferases0.003286Inherited
Spectrin repeat0.003538Inherited
Tubulin, GTPase domain0.00356Inherited
Frizzled cysteine-rich domain0.005166Inherited
EF-hand modules in multidomain proteins0.005166Inherited
BAR domain0.005166Inherited
F1F0 ATP synthase subunit C0.005166Inherited
Canonical RBD0.007476Inherited
BTB/POZ domain0.007776Inherited
Prefoldin0.007903Inherited
EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain0.008946Inherited
Intermediate filament protein, coiled coil region0.009003Inherited
Elongation factors0.01275Inherited
DBL homology domain (DH-domain)0.01275Inherited
Tetratricopeptide repeat (TPR)0.01367Inherited
Anticodon-binding domain0.01588Inherited
Ubiquitin carboxyl-terminal hydrolase UCH-L0.01588Inherited
Cu,Zn superoxide dismutase-like0.01588Inherited
BEACH domain0.01588Inherited
Ephrin ectodomain0.01588Inherited
Anticodon-binding domain of Class II aaRS0.01588Inherited
Hemocyanin middle domain0.01588Inherited
Cdc48 N-terminal domain-like0.01588Inherited
DNA polymerase III clamp loader subunits, C-terminal domain0.01588Inherited
Caspase catalytic domain0.01588Inherited
DNA gyrase/MutL, N-terminal domain0.01588Inherited
Cdc48 domain 2-like0.01588Inherited
FAD/NAD-linked reductases, N-terminal and central domains0.01682Inherited
LIM domain0.02089Inherited
Hedgehog C-terminal (Hog) autoprocessing domain0.02089Inherited
FAD/NAD-linked reductases, dimerisation (C-terminal) domain0.02121Inherited
I set domains0.02128Inherited
PDZ domain0.02804Inherited
Calcium ATPase, transduction domain A0.03342Inherited
Sm motif of small nuclear ribonucleoproteins, SNRNP0.03476Inherited
cAMP-binding domain0.03476Inherited
Nitrogenase iron protein-like0.04045Inherited
Erythroid transcription factor GATA-10.04645Inherited
Hect, E3 ligase catalytic domain0.04645Inherited
Linker histone H1/H50.05202Inherited
DNA polymerase I0.05202Inherited
DEP domain0.05494Inherited
BCR-homology GTPase activation domain (BH-domain)0.06558Inherited
Growth factor receptor domain0.08735Inherited
PHD domain0.1089Inherited
YWTD domain0.1167Inherited
First domain of FERM0.1167Inherited
Class II glutamine amidotransferases0.1167Inherited
Second domain of FERM0.125Inherited
DnaQ-like 3'-5' exonuclease0.125Inherited
Protein kinases, catalytic subunit0.1278Inherited
Calpain large subunit, catalytic domain (domain II)0.1529Inherited
Fatty acid binding protein-like0.1875Inherited
FKBP immunophilin/proline isomerase0.2235Inherited
Homeodomain0.2281Inherited
Third domain of FERM0.2312Inherited
Protein kinase cysteine-rich domain (cys2, phorbol-binding domain)0.2828Inherited
ABC transporter ATPase domain-like0.2943Inherited
Multidrug efflux transporter AcrB transmembrane domain0.3401Inherited
CCCH zinc finger0.391Inherited
CBS-domain pair0.3939Inherited
RING finger domain, C3HC40.5021Inherited
SH2 domain0.5815Inherited
Transducin (alpha subunit), insertion domain0.6424Inherited
UBC-related0.7269Inherited
ABC transporter transmembrane region0.7338Inherited
Glutathione peroxidase-like0.8828Inherited
Voltage-gated potassium channels1Inherited
Glutathione S-transferase (GST), N-terminal domain1Inherited


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Supra-domain (including individual superfamily)

(show details)
Supra-domain (Single) FDR (all) Annotation (direct or inherited)
Clathrin adaptor appendage domain0Direct
DNA ligase/mRNA capping enzyme, catalytic domain0Direct
P-loop containing nucleoside triphosphate hydrolases0Direct
Subdomain of clathrin and coatomer appendage domain0Direct
N-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor0Direct
5' to 3' exonuclease, C-terminal subdomain0Direct
PX domain0Direct
ValRS/IleRS/LeuRS editing domain0Direct
DNA repair protein MutS, domain III0Direct
Helical domain of Sec23/240Direct
Cullin homology domain0Direct
The spindle assembly checkpoint protein mad20Direct
DLC0Direct
Ribosomal protein L10Direct
ARM repeat0Direct
Ribosomal protein S100Direct
14-3-3 protein0Direct
Lipovitellin-phosvitin complex; beta-sheet shell regions0Direct
C-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
Ribosomal protein L10-like0Direct
Profilin (actin-binding protein)0Direct
Sec7 domain0Direct
Lipovitellin-phosvitin complex, superhelical domain0Direct
LEM domain0Direct
Zn-finger domain of Sec23/240Direct
VPS9 domain0Direct
Restriction endonuclease-like0Direct
Lesion bypass DNA polymerase (Y-family), little finger domain0Direct
HSP90 C-terminal domain0Direct
C-terminal, gelsolin-like domain of Sec23/240Direct
Smc hinge domain0Direct
RBP11-like subunits of RNA polymerase0Direct
Histone-fold7.012e-16Direct
Nicotinic receptor ligand binding domain-like0.0000000000007233Direct
Nucleic acid-binding proteins0.000000000002332Direct
Neurotransmitter-gated ion-channel transmembrane pore0.00000000001416Direct
"Winged helix" DNA-binding domain0.00000000001712Direct
Skp1 dimerisation domain-like0.00000000007227Direct
PH domain-like0.0000000001765Direct
WD40 repeat-like0.000000003729Direct
FYVE/PHD zinc finger0.0000003778Direct
GroEL apical domain-like0.000003412Direct
Translation proteins SH3-like domain0.000007886Direct
N-terminal nucleophile aminohydrolases (Ntn hydrolases)0.000008994Direct
SNARE-like0.00001158Direct
GroEL equatorial domain-like0.00001295Direct
t-snare proteins0.00001295Direct
GroEL-intermediate domain like0.00001295Direct
C2 domain (Calcium/lipid-binding domain, CaLB)0.00001321Direct
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases0.0000275Direct
Translation proteins0.00002804Direct
SH3-domain0.00003766Direct
Activating enzymes of the ubiquitin-like proteins0.00004889Direct
Calponin-homology domain, CH-domain0.00009641Direct
ENTH/VHS domain0.0001304Direct
Actin-like ATPase domain0.0001442Direct
Cyclin-like0.0002293Direct
HLH, helix-loop-helix DNA-binding domain0.0002401Direct
Tubulin C-terminal domain-like0.0003194Direct
Spectrin repeat0.0003802Direct
Lamin A/C globular tail domain0.0003802Direct
Ribosomal protein S5 domain 2-like0.0005108Direct
Clc chloride channel0.0006785Direct
Sec1/munc18-like (SM) proteins0.0006785Direct
beta and beta-prime subunits of DNA dependent RNA-polymerase0.0006785Direct
Tubulin nucleotide-binding domain-like0.0008544Direct
DNA/RNA polymerases0.0009978Direct
Class II aaRS ABD-related0.001055Inherited
Prefoldin0.001055Inherited
Calpain large subunit, middle domain (domain III)0.001055Inherited
PIN domain-like0.001055Inherited
Nucleotidylyl transferase0.001206Inherited
RNA-binding domain, RBD0.00181Inherited
Ribosomal proteins S24e, L23 and L15e0.002486Inherited
Frizzled cysteine-rich domain0.002486Inherited
CAD & PB1 domains0.002486Inherited
F1F0 ATP synthase subunit C0.002486Inherited
Class II aaRS and biotin synthetases0.002651Inherited
Intermediate filament protein, coiled coil region0.003146Inherited
Sm-like ribonucleoproteins0.003415Inherited
DBL homology domain (DH-domain)0.003415Inherited
DEATH domain0.003467Inherited
Cullin repeat-like0.003467Inherited
EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain0.003467Inherited
L30e-like0.003467Inherited
Growth factor receptor domain0.004276Inherited
Metal cation-transporting ATPase, ATP-binding domain N0.004568Inherited
Protein kinase-like (PK-like)0.004795Inherited
Ubiquitin-like0.005836Inherited
GTPase activation domain, GAP0.006593Inherited
TPR-like0.006606Inherited
BAR/IMD domain-like0.006618Inherited
Calcium ATPase, transmembrane domain M0.007498Inherited
Hedgehog/intein (Hint) domain0.008477Inherited
SET domain0.008679Inherited
ADC-like0.008923Inherited
Cdc48 domain 2-like0.008923Inherited
Terpenoid cyclases/Protein prenyltransferases0.008923Inherited
BEACH domain0.008923Inherited
Cu,Zn superoxide dismutase-like0.008923Inherited
beta-sandwich domain of Sec23/240.008923Inherited
post-AAA+ oligomerization domain-like0.008923Inherited
Integrin domains0.008923Inherited
Zinc beta-ribbon0.009917Inherited
Calcium ATPase, transduction domain A0.00992Inherited
Translational machinery components0.01064Inherited
FAD/NAD-linked reductases, dimerisation (C-terminal) domain0.01064Inherited
Di-copper centre-containing domain0.01064Inherited
Quinoprotein alcohol dehydrogenase-like0.02067Inherited
Hect, E3 ligase catalytic domain0.02191Inherited
cAMP-binding domain-like0.02312Inherited
YWTD domain0.02729Inherited
Invertebrate chitin-binding proteins0.03074Inherited
Chromo domain-like0.03098Inherited
S15/NS1 RNA-binding domain0.03207Inherited
Caspase-like0.03207Inherited
Cupredoxins0.03207Inherited
Tubby C-terminal domain-like0.03207Inherited
Nucleotide-diphospho-sugar transferases0.04913Inherited
PLC-like phosphodiesterases0.04987Inherited
Second domain of FERM0.07931Inherited
Myosin rod fragments0.09157Inherited
Cysteine-rich domain0.09725Inherited
PDZ domain-like0.107Inherited
HAD-like0.1071Inherited
Homeodomain-like0.1081Inherited
FKBP-like0.1332Inherited
BRCT domain0.1724Inherited
CCCH zinc finger0.1994Inherited
p53-like transcription factors0.2365Inherited
UBC-like0.2447Inherited
SH2 domain0.2549Inherited
Multidrug efflux transporter AcrB transmembrane domain0.2598Inherited
CBS-domain pair0.301Inherited
Cysteine proteinases0.4061Inherited
Transducin (alpha subunit), insertion domain0.4415Inherited
PLP-dependent transferases0.4885Inherited
HSP20-like chaperones0.493Inherited
E set domains0.5104Inherited
Clavaminate synthase-like0.5919Inherited
Immunoglobulin0.6107Inherited
Lipocalins0.6395Inherited
ABC transporter transmembrane region0.6486Inherited
RING/U-box0.7581Inherited
EF-hand0.7649Inherited
POZ domain0.8531Inherited
S-adenosyl-L-methionine-dependent methyltransferases0.9218Inherited
(Phosphotyrosine protein) phosphatases II0.9748Inherited
Voltage-gated potassium channels0.9876Inherited
Metallo-dependent phosphatases0.9989Inherited
Saposin0.9992Inherited
Thioredoxin-like1Inherited

(show details)
Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
56091,50249
  • 56091 - DNA ligase/mRNA capping enzyme, catalytic domain
  • 50249 - Nucleic acid-binding proteins
  • 0Direct
    46785,144074
  • 46785 - "Winged helix" DNA-binding domain
  • 144074 - E2F-DP heterodimerization region
  • 0Direct
    50692,54585
  • 50692 - ADC-like
  • 54585 - Cdc48 domain 2-like
  • 0Direct
    82919,53300
  • 82919 - Zn-finger domain of Sec23/24
  • 53300 - vWA-like
  • 0Direct
    64356,49447
  • 64356 - SNARE-like
  • 49447 - Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor
  • 0Direct
    48425,50729
  • 48425 - Sec7 domain
  • 50729 - PH domain-like
  • 0Direct
    52540,47917
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 47917 - C-terminal domain of alpha and beta subunits of F1 ATP synthase
  • 0Direct
    74788,75632
  • 74788 - Cullin repeat-like
  • 75632 - Cullin homology domain
  • 0Direct
    81811,82754
  • 81811 - Helical domain of Sec23/24
  • 82754 - C-terminal, gelsolin-like domain of Sec23/24
  • 0Direct
    57863,48403
  • 57863 - ArfGap/RecO-like zinc finger
  • 48403 - Ankyrin repeat
  • 0Direct
    47473,51695
  • 47473 - EF-hand
  • 51695 - PLC-like phosphodiesterases
  • 0Direct
    56672,100879
  • 56672 - DNA/RNA polymerases
  • 100879 - Lesion bypass DNA polymerase (Y-family), little finger domain
  • 0Direct
    48334,52540
  • 48334 - DNA repair protein MutS, domain III
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    75632,46785
  • 75632 - Cullin homology domain
  • 46785 - "Winged helix" DNA-binding domain
  • 0Direct
    50677,52374
  • 50677 - ValRS/IleRS/LeuRS editing domain
  • 52374 - Nucleotidylyl transferase
  • 0Direct
    48431,56968
  • 48431 - Lipovitellin-phosvitin complex, superhelical domain
  • 56968 - Lipovitellin-phosvitin complex; beta-sheet shell regions
  • 0Direct
    51695,49562
  • 51695 - PLC-like phosphodiesterases
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 0Direct
    49348,55711
  • 49348 - Clathrin adaptor appendage domain
  • 55711 - Subdomain of clathrin and coatomer appendage domain
  • 0Direct
    49562,48371
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 48371 - ARM repeat
  • 0Direct
    54585,52540
  • 54585 - Cdc48 domain 2-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    50729,47473
  • 50729 - PH domain-like
  • 47473 - EF-hand
  • 0Direct
    57903,51197
  • 57903 - FYVE/PHD zinc finger
  • 51197 - Clavaminate synthase-like
  • 0Direct
    56968,48431
  • 56968 - Lipovitellin-phosvitin complex; beta-sheet shell regions
  • 48431 - Lipovitellin-phosvitin complex, superhelical domain
  • 0Direct
    55874,54211
  • 55874 - ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
  • 54211 - Ribosomal protein S5 domain 2-like
  • 0Direct
    63712,90112
  • 63712 - Nicotinic receptor ligand binding domain-like
  • 90112 - Neurotransmitter-gated ion-channel transmembrane pore
  • 0.00000000001416Direct
    54695,81382
  • 54695 - POZ domain
  • 81382 - Skp1 dimerisation domain-like
  • 0.00000000001784Direct
    48371,48371
  • 48371 - ARM repeat
  • 48371 - ARM repeat
  • 0.0000000485Direct
    48592,54849
  • 48592 - GroEL equatorial domain-like
  • 54849 - GroEL-intermediate domain like
  • 0.00001295Direct
    54849,52029
  • 54849 - GroEL-intermediate domain like
  • 52029 - GroEL apical domain-like
  • 0.00001295Direct
    53067,53067
  • 53067 - Actin-like ATPase domain
  • 53067 - Actin-like ATPase domain
  • 0.00003157Direct
    57196,57196
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.00009641Direct
    47954,47954
  • 47954 - Cyclin-like
  • 47954 - Cyclin-like
  • 0.0001304Direct
    54001,49758
  • 54001 - Cysteine proteinases
  • 49758 - Calpain large subunit, middle domain (domain III)
  • 0.000183Direct
    46966,46966
  • 46966 - Spectrin repeat
  • 46966 - Spectrin repeat
  • 0.000183Direct
    57716,57716
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 0.000273Direct
    52490,55307
  • 52490 - Tubulin nucleotide-binding domain-like
  • 55307 - Tubulin C-terminal domain-like
  • 0.0008544Direct
    48452,48452
  • 48452 - TPR-like
  • 48452 - TPR-like
  • 0.0008837Direct
    52540,50447
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 50447 - Translation proteins
  • 0.00179Inherited
    48371,56112
  • 48371 - ARM repeat
  • 56112 - Protein kinase-like (PK-like)
  • 0.002486Inherited
    52374,47323
  • 52374 - Nucleotidylyl transferase
  • 47323 - Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
  • 0.003413Inherited
    50447,50465
  • 50447 - Translation proteins
  • 50465 - EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain
  • 0.003467Inherited
    81660,56784
  • 81660 - Metal cation-transporting ATPase, ATP-binding domain N
  • 56784 - HAD-like
  • 0.004568Inherited
    55550,50044
  • 55550 - SH2 domain
  • 50044 - SH3-domain
  • 0.008923Inherited
    55681,52954
  • 55681 - Class II aaRS and biotin synthetases
  • 52954 - Class II aaRS ABD-related
  • 0.008923Inherited
    52540,48019
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 48019 - post-AAA+ oligomerization domain-like
  • 0.008923Inherited
    81333,81333
  • 81333 - F1F0 ATP synthase subunit C
  • 81333 - F1F0 ATP synthase subunit C
  • 0.008923Inherited
    49265,48726
  • 49265 - Fibronectin type III
  • 48726 - Immunoglobulin
  • 0.008923Inherited
    51905,55424
  • 51905 - FAD/NAD(P)-binding domain
  • 55424 - FAD/NAD-linked reductases, dimerisation (C-terminal) domain
  • 0.01064Inherited
    54928,54928
  • 54928 - RNA-binding domain, RBD
  • 54928 - RNA-binding domain, RBD
  • 0.01165Inherited
    48065,50729
  • 48065 - DBL homology domain (DH-domain)
  • 50729 - PH domain-like
  • 0.01329Inherited
    50044,50044
  • 50044 - SH3-domain
  • 50044 - SH3-domain
  • 0.02729Inherited
    50044,55550
  • 50044 - SH3-domain
  • 55550 - SH2 domain
  • 0.02729Inherited
    54534,54534
  • 54534 - FKBP-like
  • 54534 - FKBP-like
  • 0.03207Inherited
    50249,55681
  • 50249 - Nucleic acid-binding proteins
  • 55681 - Class II aaRS and biotin synthetases
  • 0.03207Inherited
    52540,52540
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.03699Inherited
    47031,50729
  • 47031 - Second domain of FERM
  • 50729 - PH domain-like
  • 0.04987Inherited
    53098,56672
  • 53098 - Ribonuclease H-like
  • 56672 - DNA/RNA polymerases
  • 0.07133Inherited
    57424,57424
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 0.07507Inherited
    54236,47031
  • 54236 - Ubiquitin-like
  • 47031 - Second domain of FERM
  • 0.1435Inherited
    90229,90229
  • 90229 - CCCH zinc finger
  • 90229 - CCCH zinc finger
  • 0.1861Inherited
    48726,49265
  • 48726 - Immunoglobulin
  • 49265 - Fibronectin type III
  • 0.1861Inherited
    48726,48726
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 0.2305Inherited
    52540,90123
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 90123 - ABC transporter transmembrane region
  • 0.264Inherited
    47895,52540
  • 47895 - Transducin (alpha subunit), insertion domain
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.4415Inherited
    90123,52540
  • 90123 - ABC transporter transmembrane region
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.6486Inherited
    52833,47616
  • 52833 - Thioredoxin-like
  • 47616 - GST C-terminal domain-like
  • 1Inherited
    55550,56112
  • 55550 - SH2 domain
  • 56112 - Protein kinase-like (PK-like)
  • 1Inherited

    (show details)
    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    74788,75632,46785
  • 74788 - Cullin repeat-like
  • 75632 - Cullin homology domain
  • 46785 - "Winged helix" DNA-binding domain
  • 0Direct
    46966,46966,46966
  • 46966 - Spectrin repeat
  • 46966 - Spectrin repeat
  • 46966 - Spectrin repeat
  • 0Direct
    50692,54585,52540
  • 50692 - ADC-like
  • 54585 - Cdc48 domain 2-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    50729,47473,51695
  • 50729 - PH domain-like
  • 47473 - EF-hand
  • 51695 - PLC-like phosphodiesterases
  • 0Direct
    49562,48371,56112
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 48371 - ARM repeat
  • 56112 - Protein kinase-like (PK-like)
  • 0Direct
    56968,48431,56968
  • 56968 - Lipovitellin-phosvitin complex; beta-sheet shell regions
  • 48431 - Lipovitellin-phosvitin complex, superhelical domain
  • 56968 - Lipovitellin-phosvitin complex; beta-sheet shell regions
  • 0Direct
    54585,52540,52540
  • 54585 - Cdc48 domain 2-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    48592,54849,52029
  • 48592 - GroEL equatorial domain-like
  • 54849 - GroEL-intermediate domain like
  • 52029 - GroEL apical domain-like
  • 0.00001295Direct
    57716,57716,57716
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 0.0003193Direct
    81660,56784,81665
  • 81660 - Metal cation-transporting ATPase, ATP-binding domain N
  • 56784 - HAD-like
  • 81665 - Calcium ATPase, transmembrane domain M
  • 0.002651Inherited
    52540,50447,50465
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 50447 - Translation proteins
  • 50465 - EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain
  • 0.003467Inherited
    57424,57424,57424
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 0.01715Inherited
    48726,48726,49265
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 49265 - Fibronectin type III
  • 0.04079Inherited
    54236,47031,50729
  • 54236 - Ubiquitin-like
  • 47031 - Second domain of FERM
  • 50729 - PH domain-like
  • 0.1016Inherited
    48726,48726,48726
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 0.1337Inherited
    90123,52540,90123
  • 90123 - ABC transporter transmembrane region
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 90123 - ABC transporter transmembrane region
  • 0.264Inherited
    52540,90123,52540
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 90123 - ABC transporter transmembrane region
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.264Inherited


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