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Worm Phenotype (WP): meiosis defective early emb

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Root: WP Hierarchy (worm phenotype from Wormbase Release WS226)

Shortest distance to current term (+ for parents, - for children) WP term [WP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + + 4:   organism development variant [WBPhenotype:0000531] <10>(504|576) (504|246|68)
+ + + + 4:   Variant [WBPhenotype:0000886] <4>
+ + + + 4:   development variant [WBPhenotype:0000518] <7>(506|577) (506|246|68)
+ + + 3:   lethal [WBPhenotype:0000062] <5>(498|574) (498|245|68)
+ + + 3:   physiology variant [WBPhenotype:0000519] <7>(487|558) (487|240|64)
+ + + 3:   embryonic development variant [WBPhenotype:0000749] <21>(445|531) (445|231|63)
+ + + 3:   cell development variant [WBPhenotype:0000529] <17>(128|124) (129|49|15)
+ + 2:   gametogenesis variant [WBPhenotype:0000774] <2>(65|59) (66|27|6)
+ + 2:   embryonic lethal [WBPhenotype:0000050] <7>(443|531) (443|230|63)
+ + 2:   blast cell physiology variant [WBPhenotype:0000985] <26>(152|154) (153|66|17)
+ + 2:   cell physiology variant [WBPhenotype:0000536] <26>(152|154) (153|66|17)
+ 1:   germ cell development variant [WBPhenotype:0000812] <8>(63|59) (64|27|6)
+ 1:   early embryonic lethal [WBPhenotype:0001100] <30>(61|63) (61|26|4)
+ 1:   cell division variant [WBPhenotype:0000746] <20>(55|57) (55|24|4)
0:   meiosis defective early emb [WBPhenotype:0001041] <11>(38|34) (38|16|4)
- 1:   meiotic chromosome organization variant [WBPhenotype:0002012] <11>(16|14) (16|4|1)
- 1:   meiotic progression prophase variant [WBPhenotype:0001824] <4>(24|23) (24|11|2)
- 1:   meiotic spindle defective [WBPhenotype:0001868] <4>(2|2) (2|1|0)
- 1:   developmental delay [WBPhenotype:0000848] <2>(2|1) (2|1|0)
- 1:   meiotic DNA double strand break formation variant [WBPhenotype:0001921] <1>(0|0) (0|0|0)
- 1:   polar body extrusion defective early emb [WBPhenotype:0000777] <1>(0|0) (0|0|0)
- 1:   anaphase I progression variant early embryo [WBPhenotype:0002006](0|0) (0|0|0)
- 1:   first polar body position variant [WBPhenotype:0000194](0|0) (0|0|0)
- 1:   meiosis metaphase to anaphase transition block [WBPhenotype:0001216](1|1) (1|0|0)
- 1:   no polar body formation [WBPhenotype:0000372](0|0) (0|0|0)
- 1:   passage through meiosis defective early emb [WBPhenotype:0000776](1|2) (1|0|0)


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Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
The spindle assembly checkpoint protein mad20Direct
C-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
Ribosomal protein L10Direct
N-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
LEM domain0Direct
Skp1 dimerisation domain-like0Direct
N-terminal nucleophile aminohydrolases (Ntn hydrolases)0.000003346Direct
L30e-like0.00001552Direct
DNA repair protein MutS, domain III0.00005236Direct
Cdc48 domain 2-like0.00005236Direct
ADC-like0.00005236Direct
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases0.00007303Direct
Ribosomal proteins S24e, L23 and L15e0.0002357Direct
F1F0 ATP synthase subunit C0.0002357Direct
FKBP-like0.0005813Direct
Translational machinery components0.0006405Direct
EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain0.004108Inherited
Translation proteins SH3-like domain0.005892Inherited
TPR-like0.01013Inherited
P-loop containing nucleoside triphosphate hydrolases0.01142Inherited
GroEL equatorial domain-like0.01307Inherited
GroEL-intermediate domain like0.01307Inherited
GroEL apical domain-like0.01307Inherited
Smc hinge domain0.01309Inherited
Quinoprotein alcohol dehydrogenase-like0.01309Inherited
Translation proteins0.02606Inherited
SNARE-like0.02882Inherited
Sm-like ribonucleoproteins0.04586Inherited
S15/NS1 RNA-binding domain0.06279Inherited
POZ domain0.07153Inherited
Class II aaRS and biotin synthetases0.08678Inherited
Ribosomal protein S5 domain 2-like0.2144Inherited
"Winged helix" DNA-binding domain0.2874Inherited
Nucleic acid-binding proteins0.2936Inherited
Activating enzymes of the ubiquitin-like proteins0.4704Inherited
Nucleotidylyl transferase0.5369Inherited
Protein kinase-like (PK-like)0.5967Inherited
Histone-fold0.9466Inherited


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Family

(show details)
SCOP termFDR (all)Annotation (direct or inherited)
N-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
Ribosomal protein L10Direct
LEM domain0Direct
Group II chaperonin (CCT, TRIC), intermediate domain0Direct
C-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
Proteasome subunits0Direct
Skp1 dimerisation domain-like3.143e-16Direct
RecA protein-like (ATPase-domain)0.0000005044Direct
L30e/L7ae ribosomal proteins0.000006361Direct
Cdc48 N-terminal domain-like0.0000789Direct
DNA repair protein MutS, domain III0.0000789Direct
Anticodon-binding domain0.0000789Direct
Cdc48 domain 2-like0.0000789Direct
BTB/POZ domain0.0002307Direct
Motor proteins0.0003399Direct
F1F0 ATP synthase subunit C0.0003536Direct
FKBP immunophilin/proline isomerase0.001Inherited
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases0.001Inherited
Clathrin adaptor core protein0.002033Inherited
Group II chaperonin (CCT, TRIC), ATPase domain0.002498Inherited
Group II chaperonin (CCT, TRIC), apical domain0.002498Inherited
Elongation factors0.003302Inherited
EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain0.006132Inherited
Smc hinge domain0.02707Inherited
Translational machinery components0.02707Inherited
Tetratricopeptide repeat (TPR)0.03649Inherited
Extended AAA-ATPase domain0.04752Inherited
Cold shock DNA-binding domain-like0.06584Inherited
Sm motif of small nuclear ribonucleoproteins, SNRNP0.06584Inherited
Class II aminoacyl-tRNA synthetase (aaRS)-like, catalytic domain0.08717Inherited
Nitrogenase iron protein-like0.1737Inherited
Class I aminoacyl-tRNA synthetases (RS), catalytic domain0.317Inherited
Protein kinases, catalytic subunit0.751Inherited
Nucleosome core histones0.8883Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
The spindle assembly checkpoint protein mad20Direct
Ribosomal protein L10Direct
Skp1 dimerisation domain-like0Direct
N-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
C-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
LEM domain0Direct
N-terminal nucleophile aminohydrolases (Ntn hydrolases)0.000002736Direct
L30e-like0.00001273Direct
DNA repair protein MutS, domain III0.00004314Direct
ADC-like0.00004314Direct
Cdc48 domain 2-like0.00004314Direct
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases0.00006018Direct
F1F0 ATP synthase subunit C0.0001951Direct
Ribosomal proteins S24e, L23 and L15e0.0001951Direct
FKBP-like0.0004842Direct
Translational machinery components0.0005343Direct
EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain0.00349Inherited
Translation proteins SH3-like domain0.005028Inherited
TPR-like0.008722Inherited
P-loop containing nucleoside triphosphate hydrolases0.009841Inherited
GroEL-intermediate domain like0.01129Inherited
GroEL equatorial domain-like0.01129Inherited
GroEL apical domain-like0.01129Inherited
Quinoprotein alcohol dehydrogenase-like0.01131Inherited
Smc hinge domain0.01131Inherited
Translation proteins0.0228Inherited
SNARE-like0.02527Inherited
Sm-like ribonucleoproteins0.04061Inherited
S15/NS1 RNA-binding domain0.05599Inherited
POZ domain0.06399Inherited
Class II aaRS and biotin synthetases0.07806Inherited
Ribosomal protein S5 domain 2-like0.1981Inherited
"Winged helix" DNA-binding domain0.2685Inherited
Nucleic acid-binding proteins0.2745Inherited
Activating enzymes of the ubiquitin-like proteins0.4487Inherited
Nucleotidylyl transferase0.5149Inherited
Protein kinase-like (PK-like)0.5744Inherited
Histone-fold0.9333Inherited

(show details)
Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
54695,81382
  • 54695 - POZ domain
  • 81382 - Skp1 dimerisation domain-like
  • 0Direct
    50692,54585
  • 50692 - ADC-like
  • 54585 - Cdc48 domain 2-like
  • 0Direct
    54585,52540
  • 54585 - Cdc48 domain 2-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    52540,47917
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 47917 - C-terminal domain of alpha and beta subunits of F1 ATP synthase
  • 0Direct
    81333,81333
  • 81333 - F1F0 ATP synthase subunit C
  • 81333 - F1F0 ATP synthase subunit C
  • 0.00004314Direct
    48334,52540
  • 48334 - DNA repair protein MutS, domain III
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.00004314Direct
    52374,47323
  • 52374 - Nucleotidylyl transferase
  • 47323 - Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
  • 0.00005131Direct
    50249,55681
  • 50249 - Nucleic acid-binding proteins
  • 55681 - Class II aaRS and biotin synthetases
  • 0.0001951Direct
    54534,54534
  • 54534 - FKBP-like
  • 54534 - FKBP-like
  • 0.0001951Direct
    52540,50447
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 50447 - Translation proteins
  • 0.001035Inherited
    50447,50465
  • 50447 - Translation proteins
  • 50465 - EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain
  • 0.00349Inherited
    54849,52029
  • 54849 - GroEL-intermediate domain like
  • 52029 - GroEL apical domain-like
  • 0.01129Inherited
    48592,54849
  • 48592 - GroEL equatorial domain-like
  • 54849 - GroEL-intermediate domain like
  • 0.01129Inherited
    52540,52540
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.1262Inherited
    57196,57196
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.4269Inherited
    48371,48371
  • 48371 - ARM repeat
  • 48371 - ARM repeat
  • 0.5437Inherited

    (show details)
    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    50692,54585,52540
  • 50692 - ADC-like
  • 54585 - Cdc48 domain 2-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    54585,52540,52540
  • 54585 - Cdc48 domain 2-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    52540,50447,50465
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 50447 - Translation proteins
  • 50465 - EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain
  • 0.00349Inherited
    48592,54849,52029
  • 48592 - GroEL equatorial domain-like
  • 54849 - GroEL-intermediate domain like
  • 52029 - GroEL apical domain-like
  • 0.01129Inherited


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
    Plot tree as:   Download Newick format tree:
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