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Worm Phenotype (WP): protein interaction variant

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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Root: WP Hierarchy (worm phenotype from Wormbase Release WS226)

Shortest distance to current term (+ for parents, - for children) WP term [WP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + + + 5:   Variant [WBPhenotype:0000886] <2>
+ + + + 4:   physiology variant [WBPhenotype:0000519] <14>(510|587) (510|248|68)
+ + + 3:   organism physiology variant [WBPhenotype:0000576] <9>(369|431) (372|193|56)
+ + 2:   organism homeostasis metabolism variant [WBPhenotype:0000577] <16>(361|421) (363|190|55)
+ 1:   organism metabolism processing variant [WBPhenotype:0000027] <25>(178|190) (182|87|26)
0:   protein interaction variant [WBPhenotype:0001369] <4>(47|49) (48|21|9)
- 1:   protein RNA interaction variant [WBPhenotype:0001371] <2>(0|0) (0|0|0)
- 1:   protein protein interaction variant [WBPhenotype:0001370] <2>(44|49) (45|19|8)
- 1:   microtubule polymerization variant [WBPhenotype:0001591](0|0) (0|0|0)
- 1:   protein DNA interaction variant [WBPhenotype:0001372](0|0) (0|0|0)


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
JAB1/MPN domain0Direct
RING/U-box0Direct
GroEL-intermediate domain like0Direct
GroEL equatorial domain-like0Direct
C-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
14-3-3 protein0Direct
Cu,Zn superoxide dismutase-like0Direct
N-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
Cysteine proteinases0.00000000000001252Direct
UBC-like0.00000000002483Direct
Chaperone J-domain0.0000000002735Direct
Acid proteases0.00000000259Direct
Heat shock protein 70kD (HSP70), peptide-binding domain0.000000002811Direct
Hect, E3 ligase catalytic domain0.000000002811Direct
B-box zinc-binding domain0.0000001309Direct
Cyclophilin-like0.0000004794Direct
FKBP-like0.000001019Direct
Heat shock protein 70kD (HSP70), C-terminal subdomain0.000006361Direct
GroEL apical domain-like0.000006361Direct
HSP20-like chaperones0.00001098Direct
Tubulin nucleotide-binding domain-like0.00002785Direct
Ubiquitin-like0.00004565Direct
EF-hand0.00007281Direct
Tubulin C-terminal domain-like0.00008619Direct
Actin-like ATPase domain0.000131Direct
Galactose-binding domain-like0.0001797Direct
ADC-like0.0002656Direct
WWE domain0.0002656Direct
Cdc48 domain 2-like0.0002656Direct
MIT domain0.0002656Direct
Activating enzymes of the ubiquitin-like proteins0.0002952Direct
HSP40/DnaJ peptide-binding domain0.001143Inherited
Seven-hairpin glycosidases0.003596Inherited
EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain0.005051Inherited
N-terminal nucleophile aminohydrolases (Ntn hydrolases)0.005704Inherited
UBA-like0.008736Inherited
Sec1/munc18-like (SM) proteins0.01487Inherited
Skp1 dimerisation domain-like0.02721Inherited
Cullin homology domain0.03711Inherited
PYP-like sensor domain (PAS domain)0.03711Inherited
WD40 repeat-like0.04494Inherited
Translation proteins0.05996Inherited
Cullin repeat-like0.07167Inherited
"Winged helix" DNA-binding domain0.2505Inherited
RNI-like0.6893Inherited
POZ domain0.9991Inherited
F-box domain1Inherited


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Family

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SCOP termFDR (all)Annotation (direct or inherited)
PDI-like0Direct
Cu,Zn superoxide dismutase-like0Direct
C-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
Group II chaperonin (CCT, TRIC), intermediate domain0Direct
Ubiquitin carboxyl-terminal hydrolase UCH-L0Direct
14-3-3 protein0Direct
RING finger domain, C3HC40Direct
Group II chaperonin (CCT, TRIC), ATPase domain0Direct
N-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
Pepsin-like0.00000000000003804Direct
UBC-related0.0000000000002294Direct
Papain-like0.0000000001793Direct
Chaperone J-domain0.000000000239Direct
Ubiquitin carboxyl-terminal hydrolase, UCH0.0000000077Direct
Hect, E3 ligase catalytic domain0.000000009229Direct
Heat shock protein 70kD (HSP70), peptide-binding domain0.00000007924Direct
Extended PAW domain0.0000001043Direct
B-box zinc-binding domain0.0000001062Direct
Cyclophilin (peptidylprolyl isomerase)0.0000003885Direct
Ubiquitin-related0.000001013Direct
FKBP immunophilin/proline isomerase0.000002746Direct
Heat shock protein 70kD (HSP70), C-terminal subdomain0.000005117Direct
Group II chaperonin (CCT, TRIC), apical domain0.00001847Direct
Calmodulin-like0.00002233Direct
Tubulin, GTPase domain0.000023Direct
Actin/HSP700.00002474Direct
Ubiquitin activating enzymes (UBA)0.00004728Direct
HSP200.00006646Direct
Tubulin, C-terminal domain0.00007139Direct
Cdc48 domain 2-like0.0003864Direct
WWE domain0.0003864Direct
MIT domain0.0003864Direct
Cdc48 N-terminal domain-like0.0003864Direct
Class I alpha-1;2-mannosidase, catalytic domain0.002938Inherited
Elongation factors0.004128Inherited
EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain0.004192Inherited
Sm motif of small nuclear ribonucleoproteins, SNRNP0.004411Inherited
Proteasome subunits0.007447Inherited
Cullin repeat0.0126Inherited
Sec1/munc18-like (SM) proteins0.0126Inherited
SCF ubiquitin ligase complex WHB domain0.0126Inherited
RecA protein-like (ATPase-domain)0.0126Inherited
Clathrin adaptor core protein0.03227Inherited
Cullin homology domain0.03227Inherited
Skp1 dimerisation domain-like0.03741Inherited
Thioltransferase0.1083Inherited
BTB/POZ domain0.2958Inherited
WD40-repeat0.331Inherited
F-box domain0.6421Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
GroEL equatorial domain-like0Direct
RING/U-box0Direct
14-3-3 protein0Direct
JAB1/MPN domain0Direct
N-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
GroEL-intermediate domain like0Direct
C-terminal domain of alpha and beta subunits of F1 ATP synthase0Direct
Cu,Zn superoxide dismutase-like0Direct
Cysteine proteinases0.000000000000009822Direct
UBC-like0.00000000001961Direct
Chaperone J-domain0.0000000002168Direct
Acid proteases0.00000000206Direct
Hect, E3 ligase catalytic domain0.000000002237Direct
Heat shock protein 70kD (HSP70), peptide-binding domain0.000000002237Direct
B-box zinc-binding domain0.0000001049Direct
Cyclophilin-like0.0000003862Direct
FKBP-like0.0000008231Direct
Heat shock protein 70kD (HSP70), C-terminal subdomain0.000005171Direct
GroEL apical domain-like0.000005171Direct
HSP20-like chaperones0.000008931Direct
Tubulin nucleotide-binding domain-like0.00002273Direct
Ubiquitin-like0.00003732Direct
EF-hand0.00005956Direct
Tubulin C-terminal domain-like0.00007059Direct
Actin-like ATPase domain0.0001074Direct
Galactose-binding domain-like0.0001475Direct
Cdc48 domain 2-like0.0002186Direct
MIT domain0.0002186Direct
WWE domain0.0002186Direct
ADC-like0.0002186Direct
Activating enzymes of the ubiquitin-like proteins0.0002432Direct
HSP40/DnaJ peptide-binding domain0.0009522Direct
Seven-hairpin glycosidases0.003044Inherited
EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain0.004292Inherited
N-terminal nucleophile aminohydrolases (Ntn hydrolases)0.004854Inherited
UBA-like0.007493Inherited
Sec1/munc18-like (SM) proteins0.01288Inherited
Skp1 dimerisation domain-like0.02384Inherited
Cullin homology domain0.03269Inherited
PYP-like sensor domain (PAS domain)0.03269Inherited
WD40 repeat-like0.03972Inherited
Translation proteins SH3-like domain0.04969Inherited
Translation proteins0.05338Inherited
Cullin repeat-like0.06409Inherited
"Winged helix" DNA-binding domain0.2327Inherited
RNI-like0.6684Inherited
POZ domain0.9889Inherited
F-box domain0.9917Inherited

(show details)
Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
48592,54849
  • 48592 - GroEL equatorial domain-like
  • 54849 - GroEL-intermediate domain like
  • 0Direct
    54495,46934
  • 54495 - UBC-like
  • 46934 - UBA-like
  • 0Direct
    100920,100934
  • 100920 - Heat shock protein 70kD (HSP70), peptide-binding domain
  • 100934 - Heat shock protein 70kD (HSP70), C-terminal subdomain
  • 0Direct
    54849,52029
  • 54849 - GroEL-intermediate domain like
  • 52029 - GroEL apical domain-like
  • 0Direct
    52540,47917
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 47917 - C-terminal domain of alpha and beta subunits of F1 ATP synthase
  • 0Direct
    54534,54534
  • 54534 - FKBP-like
  • 54534 - FKBP-like
  • 0Direct
    54585,52540
  • 54585 - Cdc48 domain 2-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    50692,54585
  • 50692 - ADC-like
  • 54585 - Cdc48 domain 2-like
  • 0Direct
    53067,100920
  • 53067 - Actin-like ATPase domain
  • 100920 - Heat shock protein 70kD (HSP70), peptide-binding domain
  • 0.000000002237Direct
    52833,52833
  • 52833 - Thioredoxin-like
  • 52833 - Thioredoxin-like
  • 0.00000004602Direct
    57850,57850
  • 57850 - RING/U-box
  • 57850 - RING/U-box
  • 0.00001694Direct
    57850,57845
  • 57850 - RING/U-box
  • 57845 - B-box zinc-binding domain
  • 0.00001879Direct
    52490,55307
  • 52490 - Tubulin nucleotide-binding domain-like
  • 55307 - Tubulin C-terminal domain-like
  • 0.00002273Direct
    49785,49785
  • 49785 - Galactose-binding domain-like
  • 49785 - Galactose-binding domain-like
  • 0.0001034Direct
    53067,53067
  • 53067 - Actin-like ATPase domain
  • 53067 - Actin-like ATPase domain
  • 0.0001074Direct
    49493,49493
  • 49493 - HSP40/DnaJ peptide-binding domain
  • 49493 - HSP40/DnaJ peptide-binding domain
  • 0.0009522Direct
    52540,50447
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 50447 - Translation proteins
  • 0.004176Inherited
    50447,50465
  • 50447 - Translation proteins
  • 50465 - EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain
  • 0.004292Inherited
    74788,75632
  • 74788 - Cullin repeat-like
  • 75632 - Cullin homology domain
  • 0.01288Inherited
    75632,46785
  • 75632 - Cullin homology domain
  • 46785 - "Winged helix" DNA-binding domain
  • 0.01288Inherited
    54695,81382
  • 54695 - POZ domain
  • 81382 - Skp1 dimerisation domain-like
  • 0.0146Inherited

    (show details)
    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    53067,100920,100934
  • 53067 - Actin-like ATPase domain
  • 100920 - Heat shock protein 70kD (HSP70), peptide-binding domain
  • 100934 - Heat shock protein 70kD (HSP70), C-terminal subdomain
  • 0Direct
    50692,54585,52540
  • 50692 - ADC-like
  • 54585 - Cdc48 domain 2-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    54585,52540,52540
  • 54585 - Cdc48 domain 2-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    48592,54849,52029
  • 48592 - GroEL equatorial domain-like
  • 54849 - GroEL-intermediate domain like
  • 52029 - GroEL apical domain-like
  • 0Direct
    53067,53067,100920
  • 53067 - Actin-like ATPase domain
  • 53067 - Actin-like ATPase domain
  • 100920 - Heat shock protein 70kD (HSP70), peptide-binding domain
  • 0.000000002237Direct
    52833,52833,52833
  • 52833 - Thioredoxin-like
  • 52833 - Thioredoxin-like
  • 52833 - Thioredoxin-like
  • 0.0000000998Direct
    57850,57850,57850
  • 57850 - RING/U-box
  • 57850 - RING/U-box
  • 57850 - RING/U-box
  • 0.000006577Direct
    52540,50447,50465
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 50447 - Translation proteins
  • 50465 - EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain
  • 0.004292Inherited
    74788,75632,46785
  • 74788 - Cullin repeat-like
  • 75632 - Cullin homology domain
  • 46785 - "Winged helix" DNA-binding domain
  • 0.01288Inherited


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
    Plot tree as:   Download Newick format tree:
    (show help)