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Worm Phenotype (WP): protein metabolism variant

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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Root: WP Hierarchy (worm phenotype from Wormbase Release WS226)

Shortest distance to current term (+ for parents, - for children) WP term [WP ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + + 4:   organism physiology variant [WBPhenotype:0000576] <10>(355|415) (355|191|56)
+ + + + 4:   Variant [WBPhenotype:0000886] <4>
+ + + 3:   physiology variant [WBPhenotype:0000519] <7>(487|558) (487|240|64)
+ + + 3:   organism homeostasis metabolism variant [WBPhenotype:0000577] <17>(346|406) (348|189|55)
+ + 2:   organism metabolism processing variant [WBPhenotype:0000027] <25>(171|182) (175|80|24)
+ + 2:   cell physiology variant [WBPhenotype:0000536] <26>(152|154) (153|66|17)
+ + 2:   blast cell physiology variant [WBPhenotype:0000985] <26>(152|154) (153|66|17)
+ 1:   cell homeostasis metabolism variant [WBPhenotype:0000585] <12>(65|61) (65|26|11)
+ 1:   metabolic pathway variant [WBPhenotype:0000463] <8>(35|28) (35|16|8)
0:   protein metabolism variant [WBPhenotype:0001644] <10>(28|24) (28|15|8)
- 1:   translation variant [WBPhenotype:0000121] <4>(0|0) (0|0|0)
- 1:   protein phosphorylation variant [WBPhenotype:0001349] <2>(4|4) (4|3|0)
- 1:   protein methylation variant [WBPhenotype:0001383] <1>(3|2) (3|0|0)
- 1:   proteasome core activity variant [WBPhenotype:0002009](1|1) (1|1|0)
- 1:   protein degradation variant [WBPhenotype:0001645](7|8) (7|4|4)
- 1:   protein stabilization variant [WBPhenotype:0001806](0|0) (0|0|0)
- 1:   protein transport variant [WBPhenotype:0001864](2|1) (2|1|0)
- 1:   protein turnover variant [WBPhenotype:0002010](0|0) (0|0|0)
- 1:   unfolded protein accumulation [WBPhenotype:0001486](0|0) (0|0|0)
- 1:   unfolded protein response variant [WBPhenotype:0001719](6|5) (6|4|2)


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
SET domain0.00000001646Direct
Calpain large subunit, middle domain (domain III)0.0000009709Direct
GroEL equatorial domain-like0.00000274Direct
GroEL-intermediate domain like0.00000274Direct
GroEL apical domain-like0.000006455Direct
Integrin domains0.0000161Direct
Cdc48 domain 2-like0.0000161Direct
ADC-like0.0000161Direct
F1F0 ATP synthase subunit C0.00007416Direct
PH domain-like0.0001699Direct
Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor0.0002064Direct
Spectrin repeat0.0002511Direct
N-terminal nucleophile aminohydrolases (Ntn hydrolases)0.0007128Direct
Voltage-gated potassium channels0.0007539Direct
cAMP-binding domain-like0.0009066Direct
SNARE-like0.0009066Direct
Protein kinase-like (PK-like)0.001376Inherited
Quinoprotein alcohol dehydrogenase-like0.003953Inherited
Immunoglobulin0.01863Inherited
Lipovitellin-phosvitin complex; beta-sheet shell regions0.02758Inherited
Lipovitellin-phosvitin complex, superhelical domain0.02758Inherited
Clavaminate synthase-like0.06075Inherited
Sm-like ribonucleoproteins0.06075Inherited
Transducin (alpha subunit), insertion domain0.06075Inherited
Translation proteins0.06375Inherited
Homeodomain-like0.08229Inherited
FYVE/PHD zinc finger0.1359Inherited
Cyclin-like0.8781Inherited


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Family

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SCOP termFDR (all)Annotation (direct or inherited)
Integrin domains0Direct
Histone lysine methyltransferases0.0000006159Direct
Calpain large subunit, middle domain (domain III)0.000002553Direct
Proteasome subunits0.00001358Direct
Group II chaperonin (CCT, TRIC), intermediate domain0.00002824Direct
Cdc48 N-terminal domain-like0.00002824Direct
Cdc48 domain 2-like0.00002824Direct
Group II chaperonin (CCT, TRIC), ATPase domain0.00007745Direct
F1F0 ATP synthase subunit C0.0001293Direct
Group II chaperonin (CCT, TRIC), apical domain0.0001624Direct
Calpain large subunit, catalytic domain (domain II)0.0001824Direct
Spectrin repeat0.0003031Direct
Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor0.0003572Direct
Clathrin adaptor core protein0.0007728Direct
Protein kinases, catalytic subunit0.001753Inherited
LIM domain0.003748Inherited
Voltage-gated potassium channels0.005157Inherited
Pleckstrin-homology domain (PH domain)0.008495Inherited
Lipovitellin-phosvitin complex, superhelical domain0.02768Inherited
Lipovitellin-phosvitin complex; beta-sheet shell regions0.02768Inherited
Elongation factors0.05035Inherited
I set domains0.05035Inherited
Transducin (alpha subunit), insertion domain0.06194Inherited
PHD domain0.1999Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
SET domain0.00000001323Direct
Calpain large subunit, middle domain (domain III)0.0000007899Direct
GroEL-intermediate domain like0.000002237Direct
GroEL equatorial domain-like0.000002237Direct
GroEL apical domain-like0.00000528Direct
Integrin domains0.0000132Direct
ADC-like0.0000132Direct
Cdc48 domain 2-like0.0000132Direct
F1F0 ATP synthase subunit C0.00006113Direct
PH domain-like0.0001403Direct
Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor0.0001707Direct
Spectrin repeat0.000208Direct
N-terminal nucleophile aminohydrolases (Ntn hydrolases)0.0005955Direct
Voltage-gated potassium channels0.0006304Direct
cAMP-binding domain-like0.0007592Direct
SNARE-like0.0007592Direct
Protein kinase-like (PK-like)0.001155Inherited
Quinoprotein alcohol dehydrogenase-like0.003358Inherited
Immunoglobulin0.01618Inherited
Lipovitellin-phosvitin complex; beta-sheet shell regions0.02416Inherited
Lipovitellin-phosvitin complex, superhelical domain0.02416Inherited
Sm-like ribonucleoproteins0.05409Inherited
Transducin (alpha subunit), insertion domain0.05409Inherited
Clavaminate synthase-like0.05409Inherited
Translation proteins0.05687Inherited
Homeodomain-like0.07394Inherited
FYVE/PHD zinc finger0.1239Inherited
Cyclin-like0.8621Inherited

(show details)
Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
50692,54585
  • 50692 - ADC-like
  • 54585 - Cdc48 domain 2-like
  • 0Direct
    54585,52540
  • 54585 - Cdc48 domain 2-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    54001,49758
  • 54001 - Cysteine proteinases
  • 49758 - Calpain large subunit, middle domain (domain III)
  • 0.0000002095Direct
    54849,52029
  • 54849 - GroEL-intermediate domain like
  • 52029 - GroEL apical domain-like
  • 0.000002237Direct
    48592,54849
  • 48592 - GroEL equatorial domain-like
  • 54849 - GroEL-intermediate domain like
  • 0.000002237Direct
    81333,81333
  • 81333 - F1F0 ATP synthase subunit C
  • 81333 - F1F0 ATP synthase subunit C
  • 0.0000132Direct
    46966,46966
  • 46966 - Spectrin repeat
  • 46966 - Spectrin repeat
  • 0.0003716Direct
    48065,50729
  • 48065 - DBL homology domain (DH-domain)
  • 50729 - PH domain-like
  • 0.0005168Direct
    56968,48431
  • 56968 - Lipovitellin-phosvitin complex; beta-sheet shell regions
  • 48431 - Lipovitellin-phosvitin complex, superhelical domain
  • 0.02416Inherited
    48431,56968
  • 48431 - Lipovitellin-phosvitin complex, superhelical domain
  • 56968 - Lipovitellin-phosvitin complex; beta-sheet shell regions
  • 0.02416Inherited
    48726,49265
  • 48726 - Immunoglobulin
  • 49265 - Fibronectin type III
  • 0.02416Inherited
    48726,48726
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 0.04316Inherited
    52540,50447
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 50447 - Translation proteins
  • 0.04316Inherited
    47895,52540
  • 47895 - Transducin (alpha subunit), insertion domain
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.05409Inherited
    47954,47954
  • 47954 - Cyclin-like
  • 47954 - Cyclin-like
  • 0.5698Inherited

    (show details)
    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    50692,54585,52540
  • 50692 - ADC-like
  • 54585 - Cdc48 domain 2-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    54585,52540,52540
  • 54585 - Cdc48 domain 2-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    48592,54849,52029
  • 48592 - GroEL equatorial domain-like
  • 54849 - GroEL-intermediate domain like
  • 52029 - GroEL apical domain-like
  • 0.000002237Direct
    46966,46966,46966
  • 46966 - Spectrin repeat
  • 46966 - Spectrin repeat
  • 46966 - Spectrin repeat
  • 0.0001707Direct
    57716,57716,57716
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 0.001178Inherited
    56968,48431,56968
  • 56968 - Lipovitellin-phosvitin complex; beta-sheet shell regions
  • 48431 - Lipovitellin-phosvitin complex, superhelical domain
  • 56968 - Lipovitellin-phosvitin complex; beta-sheet shell regions
  • 0.02416Inherited
    48726,48726,49265
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 49265 - Fibronectin type III
  • 0.05409Inherited
    48726,48726,48726
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 0.08452Inherited


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
    Plot tree as:   Download Newick format tree:
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