SUPERFAMILY 1.75 HMM library and genome assignments server

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PAZ domain family

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   All beta proteins [ 48724] (174)
Fold:   SH3-like barrel [ 50036] (21)
Superfamily:   PAZ domain [ 101690]
Family:   PAZ domain [ 101691] (5)


Family statistics
Genomes (227) Uniprot 2018_03 genome PDB chains (SCOP 1.75)
Domains 950 2,649 7
Proteins 947 2,643 7


Disease Ontology (DO)

(
show details) Document: DO annotation of SCOP domains

Mouse Phenotype (MP)

(show details)
MP termFDR (all)SDMP levelAnnotation (direct or inherited)
Mammalian Phenotype (MP)endocrine/exocrine gland phenotype0.003259Least InformativeInherited
Mammalian Phenotype (MP)cellular phenotype0.03372Least InformativeInherited
Mammalian Phenotype (MP)abnormal reproductive system morphology0.00157Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal reproductive system physiology0.004697Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal skin morphology0.028Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal skin adnexa morphology0.03576Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal primary sex determination0.00002902InformativeDirect
Mammalian Phenotype (MP)abnormal spermatogenesis0.00003578InformativeDirect
Mammalian Phenotype (MP)abnormal germ cell morphology0.00003799InformativeDirect
Mammalian Phenotype (MP)abnormal testis morphology0.00006478InformativeDirect
Mammalian Phenotype (MP)abnormal male reproductive system physiology0.0002838InformativeDirect
Mammalian Phenotype (MP)abnormal epidermal layer morphology0.001833InformativeInherited
Mammalian Phenotype (MP)abnormal testis weight0.0000006575Highly InformativeDirect
Mammalian Phenotype (MP)decreased male germ cell number0.000004294Highly InformativeDirect
Mammalian Phenotype (MP)small testis0.0000159Highly InformativeDirect
Mammalian Phenotype (MP)thick epidermis0.00003831Highly InformativeDirect

Document: MP annotation of SCOP domains

Worm Phenotype (WP)

(show details)
WP termFDR (all)SDWP levelAnnotation (direct or inherited)
Worm Phenotype (WP)organism metabolism processing variant0.0711Least InformativeInherited
Worm Phenotype (WP)RNA expression variant0.0000000000007047InformativeDirect
Worm Phenotype (WP)RNAi response variant0.0000000007294Highly InformativeDirect
Worm Phenotype (WP)maintenance of gene silencing variant0.000000343Highly InformativeDirect
Worm Phenotype (WP)mRNA levels increased0.0001581Highly InformativeDirect

Document: WP annotation of SCOP domains

Fly Phenotype (FP)

(show details)
FP termFDR (all)SDFP levelAnnotation (direct or inherited)
Fly Phenotype (FP)modifier of variegation0.000001388InformativeDirect
Fly Phenotype (FP)cell cycle defective0.0002453InformativeDirect
Fly Phenotype (FP)suppressor of variegation0.0000006372Highly InformativeDirect
Fly Phenotype (FP)mitotic cell cycle defective0.0000793Highly InformativeDirect

Document: FP annotation of SCOP domains

Fly Anatomy (FA)

(show details)
FA termFDR (all)SDFA levelAnnotation (direct or inherited)
Fly Anatomy (FA)egg0.0007896InformativeDirect

Document: FA annotation of SCOP domains

Zebrafish Anatomy (ZA)

(show details) Document: ZA annotation of SCOP domains

Xenopus Anatomy (XA)

(show details)
XA termFDR (all)SDXA levelAnnotation (direct or inherited)
Xenopus ANatomical entity (XAN)trunk0Least InformativeDirect
Xenopus ANatomical entity (XAN)cavitated compound organ0Least InformativeDirect

Document: XA annotation of SCOP domains

Arabidopsis Plant Ontology (AP)

(show details)
AP termFDR (all)SDAP levelAnnotation (direct or inherited)
Plant structure DEvelopment stage (PDE)C globular stage0Least InformativeDirect

Document: AP annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEC levelAnnotation (direct or inherited)
Enzyme Commission (EC)Hydrolases0Least InformativeDirect
Enzyme Commission (EC)Acting on ester bonds0Moderately InformativeDirect

Document: EC annotation of SCOP domains

Jump to [ Top of page · SCOP classification · Disease Ontology (DO) · Mouse Phenotype (MP) · Worm Phenotype (WP) · Fly Phenotype (FP) · Fly Anatomy (FA) · Zebrafish Anatomy (ZA) · Xenopus Anatomy (XA) · Arabidopsis Plant Ontology (AP) · Enzyme Commission (EC) ]

Internal database links

   
Superfamily level     Family level

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


   
Superfamily level     Family level

Alignments of sequences to 8 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Superfamily level

Browse and view proteins in genomes which have different domain combinations including a PAZ domain domain.


   
Superfamily level     Family level

Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Jump to [ Top of page · SCOP classification · Disease Ontology (DO) · Mouse Phenotype (MP) · Worm Phenotype (WP) · Fly Phenotype (FP) · Fly Anatomy (FA) · Zebrafish Anatomy (ZA) · Xenopus Anatomy (XA) · Arabidopsis Plant Ontology (AP) · Enzyme Commission (EC) · Internal database links ]