SUPERFAMILY 1.75 HMM library and genome assignments server

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CalX-beta domain family

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   All beta proteins [ 48724] (174)
Fold:   Immunoglobulin-like beta-sandwich [ 48725] (28)
Superfamily:   CalX-like [ 141072]
Family:   CalX-beta domain [ 141073]


Family statistics
Genomes (137) Uniprot 2018_03 genome PDB chains (SCOP 1.75)
Domains 824 3,501 3
Proteins 461 2,491 3


Human Phenotype (HP)

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show details)
HP termFDR (all)SDHP levelAnnotation (direct or inherited)
Phenotypic Abnormality (PA)Abnormality of the face0Least InformativeDirect
Phenotypic Abnormality (PA)Abnormality of skeletal morphology0Least InformativeDirect
Phenotypic Abnormality (PA)Abnormality of limbs0Least InformativeDirect
Phenotypic Abnormality (PA)Abnormality of the genitourinary system0.08271Least InformativeInherited
Phenotypic Abnormality (PA)Abnormality of the digestive system0.1181Least InformativeInherited
Phenotypic Abnormality (PA)Abnormality of the eye0.1446Least InformativeInherited
Phenotypic Abnormality (PA)Abnormality of limb bone morphology0Moderately InformativeDirect
Phenotypic Abnormality (PA)Abnormality of the lower limb0Moderately InformativeDirect
Phenotypic Abnormality (PA)Abnormality of connective tissue0Moderately InformativeDirect
Phenotypic Abnormality (PA)Abnormality of digestive system morphology0.004804Moderately InformativeInherited
Phenotypic Abnormality (PA)Abnormal ocular adnexa morphology0.007902Moderately InformativeInherited
Phenotypic Abnormality (PA)Abnormal reproductive system morphology0.009164Moderately InformativeInherited
Phenotypic Abnormality (PA)Abnormality of the gastrointestinal tract0.01542Moderately InformativeInherited
Phenotypic Abnormality (PA)Abnormality of the nose0.4137Moderately InformativeInherited
Phenotypic Abnormality (PA)Abnormal nasal morphology0.02311InformativeInherited
Phenotypic Abnormality (PA)Hernia0.1402InformativeInherited
Phenotypic Abnormality (PA)Midline defect of the nose0.00000002767Highly InformativeDirect
Phenotypic Abnormality (PA)Abnormal lacrimal duct morphology0.0000002061Highly InformativeDirect
Phenotypic Abnormality (PA)Abnormality of the anus0.0001052Highly InformativeDirect
Phenotypic Abnormality (PA)Abnormality of globe size0.001715Highly InformativeInherited
Phenotypic Abnormality (PA)Hernia of the abdominal wall0.002219Highly InformativeInherited
Phenotypic Abnormality (PA)Aplasia/Hypoplasia affecting the eye0.00742Highly InformativeInherited

Document: HP annotation of SCOP domains

Mouse Phenotype (MP)

(show details)
MP termFDR (all)SDMP levelAnnotation (direct or inherited)
Mammalian Phenotype (MP)abnormal craniofacial morphology0.0008875Moderately InformativeDirect
Mammalian Phenotype (MP)abnormal renal/urinary system morphology0.004058Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal skin morphology0.004532Moderately InformativeInherited
Mammalian Phenotype (MP)limbs/digits/tail phenotype0.02984Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal eye morphology0.7714Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal skin appearance0.0004793InformativeDirect
Mammalian Phenotype (MP)abnormal autopod morphology0.001736InformativeInherited
Mammalian Phenotype (MP)abnormal eyelid morphology0.009233InformativeInherited
Mammalian Phenotype (MP)microphthalmia0.000226Highly InformativeDirect
Mammalian Phenotype (MP)blistering0.0003054Highly InformativeDirect

Document: MP annotation of SCOP domains

Worm Phenotype (WP)

(show details) Document: WP annotation of SCOP domains

Zebrafish Anatomy (ZA)

(show details)
ZA termFDR (all)SDZA levelAnnotation (direct or inherited)
Zebrafish Anatomy (ZA)organism subdivision0Least InformativeDirect
Zebrafish Anatomy (ZA)anatomical cluster0Least InformativeDirect
Zebrafish Anatomy (ZA)multi-tissue structure0Least InformativeDirect
Zebrafish Anatomy (ZA)cavitated compound organ0Least InformativeDirect

Document: ZA annotation of SCOP domains

Xenopus Anatomy (XA)

(show details) Document: XA annotation of SCOP domains

Jump to [ Top of page · SCOP classification · Human Phenotype (HP) · Mouse Phenotype (MP) · Worm Phenotype (WP) · Zebrafish Anatomy (ZA) · Xenopus Anatomy (XA) ]

Internal database links

   
Superfamily level     Family level

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


   
Superfamily level     Family level

Alignments of sequences to 7 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Superfamily level

Browse and view proteins in genomes which have different domain combinations including a CalX-like domain.


   
Superfamily level     Family level

Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Jump to [ Top of page · SCOP classification · Human Phenotype (HP) · Mouse Phenotype (MP) · Worm Phenotype (WP) · Zebrafish Anatomy (ZA) · Xenopus Anatomy (XA) · Internal database links ]