SUPERFAMILY 1.75 HMM library and genome assignments server

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E2F dimerization segment family

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   Multi-domain proteins (alpha and beta) [ 56572] (66)
Fold:   E2F-DP heterodimerization region [ 144073]
Superfamily:   E2F-DP heterodimerization region [ 144074] (2)
Family:   E2F dimerization segment [ 144078]


Family statistics
Genomes (69) Uniprot 2018_03 genome PDB chains (SCOP 1.75)
Domains 172 377 1
Proteins 172 377 1


Mouse Phenotype (MP)

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show details)
MP termFDR (all)SDMP levelAnnotation (direct or inherited)
Mammalian Phenotype (MP)nervous system phenotype0Least InformativeDirect
Mammalian Phenotype (MP)endocrine/exocrine gland phenotype0Least InformativeDirect
Mammalian Phenotype (MP)cellular phenotype0Least InformativeDirect
Mammalian Phenotype (MP)mortality/aging0Least InformativeDirect
Mammalian Phenotype (MP)immune system phenotype0.01399Least InformativeInherited
Mammalian Phenotype (MP)hematopoietic system phenotype0.07877Least InformativeInherited
Mammalian Phenotype (MP)abnormal homeostasis0.1487Least InformativeInherited
Mammalian Phenotype (MP)lethality during fetal growth through weaning0Moderately InformativeDirect
Mammalian Phenotype (MP)abnormal reproductive system morphology0.0001195Moderately InformativeDirect
Mammalian Phenotype (MP)abnormal T cell morphology0.001078Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal blood cell morphology/development0.001939Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal lymphocyte cell number0.002922Moderately InformativeInherited
Mammalian Phenotype (MP)respiratory system phenotype0.004377Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal somatic sensory system morphology0.004614Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal blood cell morphology0.01103Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal eye morphology0.03009Moderately InformativeInherited
Mammalian Phenotype (MP)prenatal lethality0.06159Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal endocrine gland morphology0.1862Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal immune system organ morphology0.1983Moderately InformativeInherited
Mammalian Phenotype (MP)decreased hematopoietic cell number0.4931Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal reproductive system physiology0.5042Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal neuron morphology0.6484Moderately InformativeInherited
Mammalian Phenotype (MP)premature death0InformativeDirect
Mammalian Phenotype (MP)abnormal testis morphology0.000003676InformativeDirect
Mammalian Phenotype (MP)abnormal T cell differentiation0.00003873InformativeDirect
Mammalian Phenotype (MP)decreased cell proliferation0.00008303InformativeDirect
Mammalian Phenotype (MP)abnormal retinal neuronal layer morphology0.0004156InformativeDirect
Mammalian Phenotype (MP)abnormal fluid regulation0.0004546InformativeDirect
Mammalian Phenotype (MP)abnormal male reproductive system physiology0.0005857InformativeDirect
Mammalian Phenotype (MP)decreased neuron number0.001108InformativeInherited
Mammalian Phenotype (MP)lethality throughout fetal growth and development0.003987InformativeInherited
Mammalian Phenotype (MP)abnormal lymph organ size0.01226InformativeInherited
Mammalian Phenotype (MP)abnormal thymus morphology0.02304InformativeInherited
Mammalian Phenotype (MP)postnatal lethality0.05309InformativeInherited
Mammalian Phenotype (MP)decreased T cell number0.2627InformativeInherited
Mammalian Phenotype (MP)abnormal retinal bipolar cell morphology0.000001002Highly InformativeDirect
Mammalian Phenotype (MP)abnormal retinal ganglion cell morphology0.000007305Highly InformativeDirect
Mammalian Phenotype (MP)lethality throughout fetal growth and development, complete penetrance0.00001277Highly InformativeDirect
Mammalian Phenotype (MP)abnormal cell cycle0.00001332Highly InformativeDirect
Mammalian Phenotype (MP)male infertility0.0001016Highly InformativeDirect
Mammalian Phenotype (MP)abnormal respiratory epithelium morphology0.0001585Highly InformativeDirect
Mammalian Phenotype (MP)abnormal eye development0.0002803Highly InformativeDirect
Mammalian Phenotype (MP)postnatal lethality, incomplete penetrance0.0005206Highly InformativeDirect
Mammalian Phenotype (MP)abnormal thymus size0.0008554Highly InformativeDirect

Document: MP annotation of SCOP domains

Worm Phenotype (WP)

(show details) Document: WP annotation of SCOP domains

Xenopus Anatomy (XA)

(show details)
XA termFDR (all)SDXA levelAnnotation (direct or inherited)
Xenopus ANatomical entity (XAN)embryo0Least InformativeDirect
Xenopus ANatomical entity (XAN)urogenital system0Least InformativeDirect
Xenopus ANatomical entity (XAN)head0Least InformativeDirect
Xenopus ANatomical entity (XAN)trunk0Least InformativeDirect
Xenopus ANatomical entity (XAN)tissue0Least InformativeDirect
Xenopus ANatomical entity (XAN)cavitated compound organ0Least InformativeDirect
Xenopus ANatomical entity (XAN)ectoderm0Moderately InformativeDirect
Xenopus ANatomical entity (XAN)germ cell0Moderately InformativeDirect
Xenopus ANatomical entity (XAN)testis0Moderately InformativeDirect
Xenopus ANatomical entity (XAN)endomesoderm0InformativeDirect

Document: XA annotation of SCOP domains

Arabidopsis Plant Ontology (AP)

(show details)
AP termFDR (all)SDAP levelAnnotation (direct or inherited)
Plant ANatomical entity (PAN)shoot apex0Least InformativeDirect
Plant ANatomical entity (PAN)shoot internode0Least InformativeDirect
Plant ANatomical entity (PAN)root0Least InformativeDirect
Plant ANatomical entity (PAN)plant embryo0Least InformativeDirect
Plant ANatomical entity (PAN)seed0Least InformativeDirect
Plant ANatomical entity (PAN)vascular leaf0Least InformativeDirect
Plant ANatomical entity (PAN)megasporophyll0Least InformativeDirect
Plant ANatomical entity (PAN)sepal0Least InformativeDirect
Plant ANatomical entity (PAN)petal0Least InformativeDirect
Plant ANatomical entity (PAN)stem0Least InformativeDirect
Plant ANatomical entity (PAN)inflorescence0Least InformativeDirect
Plant ANatomical entity (PAN)gynoecium0Least InformativeDirect
Plant ANatomical entity (PAN)leaf lamina0Least InformativeDirect
Plant ANatomical entity (PAN)collective leaf structure0Least InformativeDirect
Plant ANatomical entity (PAN)stalk0Least InformativeDirect
Plant ANatomical entity (PAN)branch0Least InformativeDirect
Plant ANatomical entity (PAN)phyllome apex0Least InformativeDirect
Plant ANatomical entity (PAN)plant sperm cell0InformativeDirect
Plant structure DEvelopment stage (PDE)4 leaf senescence stage0Least InformativeDirect
Plant structure DEvelopment stage (PDE)E expanded cotyledon stage0Least InformativeDirect
Plant structure DEvelopment stage (PDE)F mature embryo stage0Least InformativeDirect
Plant structure DEvelopment stage (PDE)C globular stage0Least InformativeDirect
Plant structure DEvelopment stage (PDE)D bilateral stage0Least InformativeDirect
Plant structure DEvelopment stage (PDE)LP.10 ten leaves visible stage0Least InformativeDirect
Plant structure DEvelopment stage (PDE)LP.04 four leaves visible stage0Least InformativeDirect

Document: AP annotation of SCOP domains

Jump to [ Top of page · SCOP classification · Mouse Phenotype (MP) · Worm Phenotype (WP) · Xenopus Anatomy (XA) · Arabidopsis Plant Ontology (AP) ]

Internal database links

   
Superfamily level     Family level

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


   
Superfamily level     Family level

Alignments of sequences to 3 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Superfamily level

Browse and view proteins in genomes which have different domain combinations including a E2F-DP heterodimerization region domain.


   
Superfamily level     Family level

Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Jump to [ Top of page · SCOP classification · Mouse Phenotype (MP) · Worm Phenotype (WP) · Xenopus Anatomy (XA) · Arabidopsis Plant Ontology (AP) · Internal database links ]