SUPERFAMILY 1.75 HMM library and genome assignments server

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SNF-like family

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   Membrane and cell surface proteins and peptides [ 56835] (58)
Fold:   SNF-like [ 161069]
Superfamily:   SNF-like [ 161070]
Family:   SNF-like [ 161071]

Family statistics
Genomes (1,218) Uniprot 2018_03 genome PDB chains (SCOP 1.75)
Domains 4,062 22,169 2
Proteins 4,056 22,113 2

Disease Ontology (DO)

show details)
DO termFDR (all)SDDO levelAnnotation (direct or inherited)
Disease Ontology (DO)disease of mental health0.003133Moderately InformativeInherited
Disease Ontology (DO)substance dependence0.00006605InformativeDirect
Disease Ontology (DO)developmental disorder of mental health0.08129InformativeInherited
Disease Ontology (DO)bipolar disorder0.00007358Highly InformativeDirect
Disease Ontology (DO)specific developmental disorder0.0003945Highly InformativeDirect
Disease Ontology (DO)drug dependence0.000653Highly InformativeDirect

Document: DO annotation of SCOP domains

Human Phenotype (HP)

(show details) Document: HP annotation of SCOP domains

Mouse Phenotype (MP)

(show details)
MP termFDR (all)SDMP levelAnnotation (direct or inherited)
Mammalian Phenotype (MP)nervous system phenotype0.03699Least InformativeInherited
Mammalian Phenotype (MP)abnormal homeostasis0.03878Least InformativeInherited
Mammalian Phenotype (MP)abnormal synaptic transmission0.009931Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal behavior1Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal amino acid level0.00002215InformativeDirect
Mammalian Phenotype (MP)abnormal behavioral response to xenobiotic0.00004861InformativeDirect
Mammalian Phenotype (MP)abnormal CNS synaptic transmission0.0004707InformativeDirect
Mammalian Phenotype (MP)abnormal learning/memory/conditioning0.003364InformativeInherited
Mammalian Phenotype (MP)abnormal emotion/affect behavior0.01633InformativeInherited
Mammalian Phenotype (MP)abnormal associative learning0.00008128Highly InformativeDirect
Mammalian Phenotype (MP)abnormal response to novelty0.06971Highly InformativeInherited

Document: MP annotation of SCOP domains

Worm Phenotype (WP)

(show details)
WP termFDR (all)SDWP levelAnnotation (direct or inherited)
Worm Phenotype (WP)organism behavior variant0.0006358Least InformativeDirect
Worm Phenotype (WP)movement variant0.0000001037Moderately InformativeDirect
Worm Phenotype (WP)locomotion variant0.00001909Moderately InformativeDirect
Worm Phenotype (WP)body region morphology variant0.00006303Moderately InformativeDirect
Worm Phenotype (WP)organism segment morphology variant0.00006303Moderately InformativeDirect
Worm Phenotype (WP)developmental morphology variant0.00006351Moderately InformativeDirect
Worm Phenotype (WP)adult body morphology variant0.000064Moderately InformativeDirect
Worm Phenotype (WP)body morphology variant0.00007184Moderately InformativeDirect
Worm Phenotype (WP)head movement variant0InformativeDirect
Worm Phenotype (WP)body posture variant6.282e-16InformativeDirect
Worm Phenotype (WP)body bend variant0.000000000000001883InformativeDirect
Worm Phenotype (WP)foraging behavior variant0.00000000000004125InformativeDirect
Worm Phenotype (WP)forward locomotion variant0.000001005InformativeDirect
Worm Phenotype (WP)velocity of movement variant0.0002372InformativeDirect
Worm Phenotype (WP)directionality variant0.006803InformativeInherited
Worm Phenotype (WP)small0.5672InformativeInherited
Worm Phenotype (WP)locomotion reduced1InformativeInherited
Worm Phenotype (WP)coiling frequency0.00000000000004936Highly InformativeDirect
Worm Phenotype (WP)forward point velocity variant0.0000000000001654Highly InformativeDirect
Worm Phenotype (WP)backward point velocity variant0.0000000000002295Highly InformativeDirect
Worm Phenotype (WP)fat0.000000444Highly InformativeDirect
Worm Phenotype (WP)pausing variant0.0000007327Highly InformativeDirect
Worm Phenotype (WP)short0.000007239Highly InformativeDirect
Worm Phenotype (WP)roaming variant0.01025Highly InformativeInherited
Worm Phenotype (WP)foraging hyperactive0.02162Highly InformativeInherited

Document: WP annotation of SCOP domains

Fly Anatomy (FA)

(show details) Document: FA annotation of SCOP domains

Xenopus Anatomy (XA)

(show details) Document: XA annotation of SCOP domains

Jump to [ Top of page · SCOP classification · Disease Ontology (DO) · Human Phenotype (HP) · Mouse Phenotype (MP) · Worm Phenotype (WP) · Fly Anatomy (FA) · Xenopus Anatomy (XA) ]

Internal database links

Superfamily level     Family level

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.

Superfamily level     Family level

Alignments of sequences to 1 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.

Superfamily level

Browse and view proteins in genomes which have different domain combinations including a SNF-like domain.

Superfamily level     Family level

Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.

Jump to [ Top of page · SCOP classification · Disease Ontology (DO) · Human Phenotype (HP) · Mouse Phenotype (MP) · Worm Phenotype (WP) · Fly Anatomy (FA) · Xenopus Anatomy (XA) · Internal database links ]