SUPERFAMILY 1.75 HMM library and genome assignments server

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Globins family

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   All alpha proteins [ 46456] (284)
Fold:   Globin-like [ 46457] (2)
Superfamily:   Globin-like [ 46458] (4)
Family:   Globins [ 46463] (26)


Family statistics
Genomes (1,029) Uniprot 2018_03 genome PDB chains (SCOP 1.75)
Domains 2,185 14,222 244
Proteins 2,166 14,182 238


Enzyme Commission (EC)

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show details)
EC termFDR (all)SDEO levelAnnotation (direct or inherited)
Enzyme Commission (EC)Oxidoreductases0Least InformativeDirect
Enzyme Commission (EC)Acting on paired donors, with incorporation or red0Moderately InformativeDirect
Enzyme Commission (EC)With NADH or NADPH as one donor, and incorporation0Highly InformativeDirect

Document: EC annotation of SCOP domains

Disease Ontology (DO)

(show details)
DO termFDR (all)SDDO levelAnnotation (direct or inherited)
Disease Ontology (DO)genetic disease0.0002833Moderately InformativeDirect
Disease Ontology (DO)hematopoietic system disease0.0009647Moderately InformativeDirect
Disease Ontology (DO)lower respiratory tract disease0.04893Moderately InformativeInherited
Disease Ontology (DO)autosomal recessive disease0.000001818InformativeDirect
Disease Ontology (DO)anemia0.00000832Highly InformativeDirect
Disease Ontology (DO)in situ carcinoma0.00005054Highly InformativeDirect

Document: DO annotation of SCOP domains

Human Phenotype (HP)

(show details)
HP termFDR (all)SDHP levelAnnotation (direct or inherited)
Mode of Inheritance (MI)Autosomal dominant inheritance0Least InformativeDirect
Phenotypic Abnormality (PA)Abnormality of the immune system0.01464Least InformativeInherited
Phenotypic Abnormality (PA)Abnormality of the integument0.05353Least InformativeInherited
Phenotypic Abnormality (PA)Abnormality of the cardiovascular system0.05715Least InformativeInherited
Phenotypic Abnormality (PA)Abnormality of the digestive system0.07697Least InformativeInherited
Phenotypic Abnormality (PA)Abnormality of skeletal morphology0.09644Least InformativeInherited
Phenotypic Abnormality (PA)Abnormality of the face0.5629Least InformativeInherited
Phenotypic Abnormality (PA)Abnormality of blood and blood-forming tissues0Moderately InformativeDirect
Phenotypic Abnormality (PA)Abnormality of the lymphatic system0.00009298Moderately InformativeDirect
Phenotypic Abnormality (PA)Abnormality of the abdominal organs0.002052Moderately InformativeInherited
Phenotypic Abnormality (PA)Anemia0InformativeDirect
Phenotypic Abnormality (PA)Splenomegaly0.00000605InformativeDirect
Phenotypic Abnormality (PA)Abnormal liver morphology0.0002682InformativeDirect
Phenotypic Abnormality (PA)Hepatomegaly0.00002808Highly InformativeDirect
Phenotypic Abnormality (PA)Anemia of inadequate production0.002027Highly InformativeInherited
Phenotypic Abnormality (PA)Hemolytic anemia1Highly InformativeInherited

Document: HP annotation of SCOP domains

Worm Phenotype (WP)

(show details) Document: WP annotation of SCOP domains

Xenopus Anatomy (XA)

(show details)
XA termFDR (all)SDXA levelAnnotation (direct or inherited)
Xenopus ANatomical entity (XAN)head0Least InformativeDirect
Xenopus ANatomical entity (XAN)tissue0.639Least InformativeInherited
Xenopus ANatomical entity (XAN)embryo0.7442Least InformativeInherited
Xenopus ANatomical entity (XAN)embryonic structure0.2628Moderately InformativeInherited
Xenopus ANatomical entity (XAN)mesoderm0.06507InformativeInherited
Xenopus ANatomical entity (XAN)ventral blood island0.0000001238Highly InformativeDirect
Xenopus ANatomical entity (XAN)circulatory system0.00002481Highly InformativeDirect
Xenopus ANatomical entity (XAN)lateral plate mesoderm0.001402Highly InformativeInherited
Xenopus DEvelopment stage (XDE)post-embryonic stage0Least InformativeDirect

Document: XA annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEC levelAnnotation (direct or inherited)
Enzyme Commission (EC)Oxidoreductases0Least InformativeDirect
Enzyme Commission (EC)Transferases1Least InformativeInherited
Enzyme Commission (EC)Nucleotidyltransferases0.1629Moderately InformativeInherited
Enzyme Commission (EC)Acting on paired donors, with incorporation or reduction of molecular oxygen. The oxygen incorporate0InformativeDirect

Document: EC annotation of SCOP domains

Jump to [ Top of page · SCOP classification · Enzyme Commission (EC) · Disease Ontology (DO) · Human Phenotype (HP) · Worm Phenotype (WP) · Xenopus Anatomy (XA) · Enzyme Commission (EC) ]

Internal database links

   
Superfamily level     Family level

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


   
Superfamily level     Family level

Alignments of sequences to 232 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Superfamily level

Browse and view proteins in genomes which have different domain combinations including a Globin-like domain.


   
Superfamily level     Family level

Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Jump to [ Top of page · SCOP classification · Enzyme Commission (EC) · Disease Ontology (DO) · Human Phenotype (HP) · Worm Phenotype (WP) · Xenopus Anatomy (XA) · Enzyme Commission (EC) · Internal database links ]