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Homeodomain family

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   All alpha proteins [ 46456] (284)
Fold:   DNA/RNA-binding 3-helical bundle [ 46688] (14)
Superfamily:   Homeodomain-like [ 46689] (19)
Family:   Homeodomain [ 46690] (40)


Family statistics
Genomes (186) Uniprot 2018_03 genome PDB chains (SCOP 1.75)
Domains 4,632 12,364 56
Proteins 4,623 12,337 56


Disease Ontology (DO)

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show details)
DO termFDR (all)SDDO levelAnnotation (direct or inherited)
Disease Ontology (DO)physical disorder0.0004572InformativeDirect

Document: DO annotation of SCOP domains

Human Phenotype (HP)

(show details)
HP termFDR (all)SDHP levelAnnotation (direct or inherited)
Mode of Inheritance (MI)Autosomal dominant inheritance0.0006011Least InformativeDirect
Phenotypic Abnormality (PA)Abnormality of the eye0.02044Least InformativeInherited
Phenotypic Abnormality (PA)Abnormality of the genitourinary system0.1924Least InformativeInherited
Phenotypic Abnormality (PA)Abnormality of skeletal morphology0.2356Least InformativeInherited
Phenotypic Abnormality (PA)Abnormality of limbs0.4014Least InformativeInherited
Phenotypic Abnormality (PA)Abnormality of the face0.4754Least InformativeInherited
Phenotypic Abnormality (PA)Abnormality of nervous system morphology0.6807Least InformativeInherited
Phenotypic Abnormality (PA)Abnormality of the digestive system0.9323Least InformativeInherited
Phenotypic Abnormality (PA)Abnormality of the endocrine system0.1115Moderately InformativeInherited
Phenotypic Abnormality (PA)Abnormality of the upper urinary tract0.3362Moderately InformativeInherited
Phenotypic Abnormality (PA)Aplasia/Hypoplasia involving the central nervous system0.3793Moderately InformativeInherited
Phenotypic Abnormality (PA)Abnormality of limb bone morphology0.4205Moderately InformativeInherited
Phenotypic Abnormality (PA)Abnormality of the upper limb0.452Moderately InformativeInherited
Phenotypic Abnormality (PA)Abnormality of the nose0.5485Moderately InformativeInherited
Phenotypic Abnormality (PA)Abnormality of forebrain morphology0.5666Moderately InformativeInherited
Phenotypic Abnormality (PA)Abnormality of the vertebral column0.8004Moderately InformativeInherited
Phenotypic Abnormality (PA)Abnormality of the abdominal organs0.9369Moderately InformativeInherited
Phenotypic Abnormality (PA)Abnormal oral cavity morphology1Moderately InformativeInherited
Phenotypic Abnormality (PA)Abnormal lip morphology0.003699InformativeInherited
Phenotypic Abnormality (PA)Abnormality of the fontanelles or cranial sutures0.01457InformativeInherited
Phenotypic Abnormality (PA)Abnormal palate morphology0.02595InformativeInherited
Phenotypic Abnormality (PA)Abnormality of the thyroid gland0.04659InformativeInherited
Phenotypic Abnormality (PA)Abnormal nasal morphology0.07491InformativeInherited
Phenotypic Abnormality (PA)Abnormal vertebral morphology0.1275InformativeInherited
Phenotypic Abnormality (PA)Abnormality of the cerebral subcortex0.1436InformativeInherited
Phenotypic Abnormality (PA)Abnormal circulating hormone level0.1719InformativeInherited
Phenotypic Abnormality (PA)Short stature0.3802InformativeInherited
Phenotypic Abnormality (PA)Abnormal fundus morphology0.4413InformativeInherited
Phenotypic Abnormality (PA)Abnormality of the anterior pituitary0.5026InformativeInherited
Phenotypic Abnormality (PA)Aplasia/hypoplasia of the extremities0.5175InformativeInherited
Phenotypic Abnormality (PA)Aplasia/Hypoplasia affecting the eye0.000003996Highly InformativeDirect
Phenotypic Abnormality (PA)Large fontanelles0.000006547Highly InformativeDirect
Phenotypic Abnormality (PA)Abnormality of periauricular region0.0002265Highly InformativeDirect
Phenotypic Abnormality (PA)Agenesis of corpus callosum0.0005428Highly InformativeDirect
Phenotypic Abnormality (PA)Abnormal 2nd finger morphology0.001431Highly InformativeInherited
Phenotypic Abnormality (PA)Abnormality of circulating adrenocorticotropin level0.005563Highly InformativeInherited
Phenotypic Abnormality (PA)Midline defect of the nose0.007296Highly InformativeInherited
Phenotypic Abnormality (PA)Abnormal ureter physiology0.1317Highly InformativeInherited
Phenotypic Abnormality (PA)Cleft palate0.3853Highly InformativeInherited
Phenotypic Abnormality (PA)Short finger0.5562Highly InformativeInherited
Phenotypic Abnormality (PA)Abnormal bone structure0.7455Highly InformativeInherited

Document: HP annotation of SCOP domains

Mouse Phenotype (MP)

(show details)
MP termFDR (all)SDMP levelAnnotation (direct or inherited)
Mammalian Phenotype (MP)nervous system phenotype0.000000000002266Least InformativeDirect
Mammalian Phenotype (MP)endocrine/exocrine gland phenotype0.0000003681Least InformativeDirect
Mammalian Phenotype (MP)mortality/aging0.000001627Least InformativeDirect
Mammalian Phenotype (MP)growth/size/body region phenotype0.000002355Least InformativeDirect
Mammalian Phenotype (MP)cellular phenotype0.05586Least InformativeInherited
Mammalian Phenotype (MP)cardiovascular system phenotype0.4158Least InformativeInherited
Mammalian Phenotype (MP)abnormal homeostasis0.6721Least InformativeInherited
Mammalian Phenotype (MP)immune system phenotype1Least InformativeInherited
Mammalian Phenotype (MP)hematopoietic system phenotype1Least InformativeInherited
Mammalian Phenotype (MP)abnormal craniofacial morphology0.000000000000007866Moderately InformativeDirect
Mammalian Phenotype (MP)lethality during fetal growth through weaning0.0000000000006013Moderately InformativeDirect
Mammalian Phenotype (MP)limbs/digits/tail phenotype0.00000001062Moderately InformativeDirect
Mammalian Phenotype (MP)hearing/vestibular/ear phenotype0.0000004438Moderately InformativeDirect
Mammalian Phenotype (MP)abnormal axial skeleton morphology0.0000006201Moderately InformativeDirect
Mammalian Phenotype (MP)abnormal head morphology0.0000008728Moderately InformativeDirect
Mammalian Phenotype (MP)respiratory system phenotype0.000001773Moderately InformativeDirect
Mammalian Phenotype (MP)abnormal digestive system morphology0.001173Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal muscle morphology0.004293Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal embryo morphology0.03993Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal eye morphology0.04759Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal nervous system development0.06466Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal endocrine gland morphology0.06677Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal blood vessel morphology0.1264Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal neuron morphology0.2899Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal skin adnexa morphology0.3449Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal renal/urinary system morphology0.562Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal brain morphology0.8155Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal immune system organ morphology0.8368Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal reproductive system morphology0.959Moderately InformativeInherited
Mammalian Phenotype (MP)liver/biliary system phenotype0.9615Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal muscle physiology1Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal behavior1Moderately InformativeInherited
Mammalian Phenotype (MP)perinatal lethality0.0000000000983InformativeDirect
Mammalian Phenotype (MP)abnormal spinal cord morphology0.00002961InformativeDirect
Mammalian Phenotype (MP)abnormal gas homeostasis0.00007527InformativeDirect
Mammalian Phenotype (MP)normal phenotype0.00007784InformativeDirect
Mammalian Phenotype (MP)postnatal lethality0.00008458InformativeDirect
Mammalian Phenotype (MP)abnormal cranial nerve morphology0.0001503InformativeDirect
Mammalian Phenotype (MP)abnormal systemic artery morphology0.0005729InformativeDirect
Mammalian Phenotype (MP)abnormal neuron differentiation0.0007599InformativeDirect
Mammalian Phenotype (MP)abnormal cartilage morphology0.001379InformativeInherited
Mammalian Phenotype (MP)abnormal thoracic cage morphology0.004526InformativeInherited
Mammalian Phenotype (MP)abnormal consumption behavior0.01152InformativeInherited
Mammalian Phenotype (MP)abnormal mouth morphology0.0234InformativeInherited
Mammalian Phenotype (MP)abnormal developmental patterning0.0279InformativeInherited
Mammalian Phenotype (MP)abnormal brain development0.04715InformativeInherited
Mammalian Phenotype (MP)abnormal nervous system tract morphology0.08198InformativeInherited
Mammalian Phenotype (MP)abnormal hearing physiology0.08445InformativeInherited
Mammalian Phenotype (MP)abnormal brain white matter morphology0.1015InformativeInherited
Mammalian Phenotype (MP)abnormal neural tube morphology0.1083InformativeInherited
Mammalian Phenotype (MP)abnormal skeleton development0.128InformativeInherited
Mammalian Phenotype (MP)abnormal anterior eye segment morphology0.1508InformativeInherited
Mammalian Phenotype (MP)abnormal thymus morphology0.2069InformativeInherited
Mammalian Phenotype (MP)abnormal pancreas morphology0.2082InformativeInherited
Mammalian Phenotype (MP)abnormal skeletal muscle morphology0.2435InformativeInherited
Mammalian Phenotype (MP)abnormal autopod morphology0.2579InformativeInherited
Mammalian Phenotype (MP)abnormal limb bone morphology0.4028InformativeInherited
Mammalian Phenotype (MP)abnormal primary sex determination0.4896InformativeInherited
Mammalian Phenotype (MP)abnormal mammary gland morphology0.5109InformativeInherited
Mammalian Phenotype (MP)abnormal limbic system morphology0.5966InformativeInherited
Mammalian Phenotype (MP)abnormal jaw morphology0.6207InformativeInherited
Mammalian Phenotype (MP)abnormal vertebral column morphology0.6371InformativeInherited
Mammalian Phenotype (MP)abnormal ovary morphology0.7668InformativeInherited
Mammalian Phenotype (MP)abnormal cerebral hemisphere morphology0.8268InformativeInherited
Mammalian Phenotype (MP)abnormal testis morphology0.8593InformativeInherited
Mammalian Phenotype (MP)abnormal metencephalon morphology0.9845InformativeInherited
Mammalian Phenotype (MP)abnormal spleen morphology1InformativeInherited
Mammalian Phenotype (MP)abnormal digestive system physiology1InformativeInherited
Mammalian Phenotype (MP)abnormal long bone morphology1InformativeInherited
Mammalian Phenotype (MP)vertebral transformation0.0000000007577Highly InformativeDirect
Mammalian Phenotype (MP)cyanosis0.000000001052Highly InformativeDirect
Mammalian Phenotype (MP)abnormal middle ear morphology0.00000000626Highly InformativeDirect
Mammalian Phenotype (MP)taste/olfaction phenotype0.0000002561Highly InformativeDirect
Mammalian Phenotype (MP)abnormal rib joint0.000002178Highly InformativeDirect
Mammalian Phenotype (MP)distended abdomen0.000003959Highly InformativeDirect
Mammalian Phenotype (MP)abnormal neuroendocrine gland morphology0.000005701Highly InformativeDirect
Mammalian Phenotype (MP)abnormal secondary palate development0.00009816Highly InformativeDirect
Mammalian Phenotype (MP)abnormal diencephalon morphology0.0001318Highly InformativeDirect
Mammalian Phenotype (MP)abnormal pancreas development0.0003502Highly InformativeDirect
Mammalian Phenotype (MP)abnormal telencephalon development0.00054Highly InformativeDirect
Mammalian Phenotype (MP)microphthalmia0.0005831Highly InformativeDirect
Mammalian Phenotype (MP)abnormal temporal bone morphology0.0008147Highly InformativeDirect
Mammalian Phenotype (MP)abnormal vas deferens morphology0.0008484Highly InformativeDirect
Mammalian Phenotype (MP)abnormal eye development0.00228Highly InformativeInherited
Mammalian Phenotype (MP)abnormal urinary system development0.005306Highly InformativeInherited
Mammalian Phenotype (MP)abnormal hindbrain development0.0101Highly InformativeInherited
Mammalian Phenotype (MP)abnormal midbrain morphology0.01133Highly InformativeInherited
Mammalian Phenotype (MP)abnormal thyroid gland morphology0.01181Highly InformativeInherited
Mammalian Phenotype (MP)abnormal thoracic aorta morphology0.01638Highly InformativeInherited
Mammalian Phenotype (MP)impaired hearing0.01971Highly InformativeInherited
Mammalian Phenotype (MP)abnormal rib morphology0.02652Highly InformativeInherited
Mammalian Phenotype (MP)abnormal sternum morphology0.03188Highly InformativeInherited
Mammalian Phenotype (MP)abnormal lens morphology0.05376Highly InformativeInherited
Mammalian Phenotype (MP)abnormal anterior uvea morphology0.06262Highly InformativeInherited
Mammalian Phenotype (MP)abnormal hypaxial muscle morphology0.101Highly InformativeInherited
Mammalian Phenotype (MP)abnormal pancreatic beta cell morphology0.112Highly InformativeInherited
Mammalian Phenotype (MP)abnormal mandible morphology0.1738Highly InformativeInherited
Mammalian Phenotype (MP)abnormal food intake0.4466Highly InformativeInherited
Mammalian Phenotype (MP)abnormal secondary palate morphology0.5381Highly InformativeInherited
Mammalian Phenotype (MP)abnormal forelimb stylopod morphology0.8534Highly InformativeInherited
Mammalian Phenotype (MP)abnormal dorsal telencephalic commissure morphology0.8828Highly InformativeInherited
Mammalian Phenotype (MP)abnormal femur morphology0.9767Highly InformativeInherited

Document: MP annotation of SCOP domains

Worm Phenotype (WP)

(show details)
WP termFDR (all)SDWP levelAnnotation (direct or inherited)
Worm Phenotype (WP)organism behavior variant0.000000005084Least InformativeDirect
Worm Phenotype (WP)cell development variant0.00000001079Least InformativeDirect
Worm Phenotype (WP)organism metabolism processing variant0.0000003798Least InformativeDirect
Worm Phenotype (WP)cell physiology variant0.2281Least InformativeInherited
Worm Phenotype (WP)blast cell physiology variant0.2281Least InformativeInherited
Worm Phenotype (WP)larval lethal0.3679Least InformativeInherited
Worm Phenotype (WP)body region morphology variant0.000000002016Moderately InformativeDirect
Worm Phenotype (WP)organism segment morphology variant0.000000002016Moderately InformativeDirect
Worm Phenotype (WP)developmental morphology variant0.000000002068Moderately InformativeDirect
Worm Phenotype (WP)adult body morphology variant0.000000002122Moderately InformativeDirect
Worm Phenotype (WP)body morphology variant0.000000003102Moderately InformativeDirect
Worm Phenotype (WP)organ system development variant0.0000000871Moderately InformativeDirect
Worm Phenotype (WP)level of transgene expression variant0.000002442Moderately InformativeDirect
Worm Phenotype (WP)movement variant0.002449Moderately InformativeInherited
Worm Phenotype (WP)locomotion variant0.5493Moderately InformativeInherited
Worm Phenotype (WP)cell division variant0.6881Moderately InformativeInherited
Worm Phenotype (WP)pattern of transgene expression variant1Moderately InformativeInherited
Worm Phenotype (WP)tail morphology variant0.0000000002053InformativeDirect
Worm Phenotype (WP)male morphology variant0.0000000009734InformativeDirect
Worm Phenotype (WP)cell fate specification variant0.000004758InformativeDirect
Worm Phenotype (WP)nervous system morphology variant0.00001046InformativeDirect
Worm Phenotype (WP)directionality variant0.03238InformativeInherited
Worm Phenotype (WP)foraging behavior variant0.06276InformativeInherited
Worm Phenotype (WP)forward locomotion variant0.08459InformativeInherited
Worm Phenotype (WP)body posture variant0.1563InformativeInherited
Worm Phenotype (WP)vulva development variant0.5199InformativeInherited
Worm Phenotype (WP)locomotion reduced0.5978InformativeInherited
Worm Phenotype (WP)cell number increased1InformativeInherited
Worm Phenotype (WP)lineage variant0.000001398Highly InformativeDirect
Worm Phenotype (WP)carbon dioxide avoidance variant0.00001627Highly InformativeDirect
Worm Phenotype (WP)neuronal cell fate specification variant0.00001833Highly InformativeDirect
Worm Phenotype (WP)forward locomotion decreased0.00003517Highly InformativeDirect
Worm Phenotype (WP)multiple anchor cells0.0001448Highly InformativeDirect
Worm Phenotype (WP)cell number decreased0.0002494Highly InformativeDirect
Worm Phenotype (WP)ectopic expression transgene0.0004081Highly InformativeDirect
Worm Phenotype (WP)loss of left right asymmetry0.0004308Highly InformativeDirect
Worm Phenotype (WP)coiling frequency0.000464Highly InformativeDirect
Worm Phenotype (WP)roaming variant0.009228Highly InformativeInherited

Document: WP annotation of SCOP domains

Fly Phenotype (FP)

(show details)
FP termFDR (all)SDFP levelAnnotation (direct or inherited)
Fly Phenotype (FP)increased mortality0.03862Least InformativeInherited
Fly Phenotype (FP)lethal - all die before end of P-stage0.07108Moderately InformativeInherited
Fly Phenotype (FP)visible0InformativeDirect
Fly Phenotype (FP)lethal - all die before end of first instar larval stage0.00000001848InformativeDirect
Fly Phenotype (FP)lethal - all die before end of embryonic stage0.000000001337Highly InformativeDirect
Fly Phenotype (FP)pair rule phenotype0.00000003327Highly InformativeDirect
Fly Phenotype (FP)homeotic0.00000009631Highly InformativeDirect
Fly Phenotype (FP)some die during embryonic stage0.0001223Highly InformativeDirect

Document: FP annotation of SCOP domains

Fly Anatomy (FA)

(show details)
FA termFDR (all)SDFA levelAnnotation (direct or inherited)
Fly Anatomy (FA)organ system subdivision0.000000000004316Least InformativeDirect
Fly Anatomy (FA)tagma0.00000000001572Least InformativeDirect
Fly Anatomy (FA)adult0.000000148Least InformativeDirect
Fly Anatomy (FA)segment0.0000007701Least InformativeDirect
Fly Anatomy (FA)anatomical group0.0004541Least InformativeDirect
Fly Anatomy (FA)embryo0.004321Least InformativeInherited
Fly Anatomy (FA)multi-tissue structure0.006975Least InformativeInherited
Fly Anatomy (FA)larva0.01002Least InformativeInherited
Fly Anatomy (FA)nervous system0.108Least InformativeInherited
Fly Anatomy (FA)somatic cell0.253Least InformativeInherited
Fly Anatomy (FA)larval tagma0.00000001734Moderately InformativeDirect
Fly Anatomy (FA)multi-cell-component structure0.0000001093Moderately InformativeDirect
Fly Anatomy (FA)appendage0.000003552Moderately InformativeDirect
Fly Anatomy (FA)ganglion0.00001221Moderately InformativeDirect
Fly Anatomy (FA)embryonic/larval nervous system0.0001705Moderately InformativeDirect
Fly Anatomy (FA)abdomen0.0003387Moderately InformativeDirect
Fly Anatomy (FA)acellular anatomical structure0.001312Moderately InformativeInherited
Fly Anatomy (FA)adult mesothoracic segment0.001376Moderately InformativeInherited
Fly Anatomy (FA)cell cluster organ0.001522Moderately InformativeInherited
Fly Anatomy (FA)sense organ0.006215Moderately InformativeInherited
Fly Anatomy (FA)neuron0.02102Moderately InformativeInherited
Fly Anatomy (FA)central nervous system0.02752Moderately InformativeInherited
Fly Anatomy (FA)adult external thorax0.1993Moderately InformativeInherited
Fly Anatomy (FA)somatic precursor cell0.5308Moderately InformativeInherited
Fly Anatomy (FA)peripheral nervous system0.7913Moderately InformativeInherited
Fly Anatomy (FA)female organism0.8945Moderately InformativeInherited
Fly Anatomy (FA)head0.9852Moderately InformativeInherited
Fly Anatomy (FA)interneuron0.0000003243InformativeDirect
Fly Anatomy (FA)embryonic/larval neuron0.00004256InformativeDirect
Fly Anatomy (FA)primordium0.00006988InformativeDirect
Fly Anatomy (FA)extended germ band embryo0.0002056InformativeDirect
Fly Anatomy (FA)mesothoracic tergum0.0002188InformativeDirect
Fly Anatomy (FA)adult external head0.0005809InformativeDirect
Fly Anatomy (FA)segmental subdivision of organ system0.0005891InformativeDirect
Fly Anatomy (FA)syncytium0.0008578InformativeDirect
Fly Anatomy (FA)synaptic neuropil0.000865InformativeDirect
Fly Anatomy (FA)muscle cell0.001021InformativeInherited
Fly Anatomy (FA)larval abdominal segment0.00153InformativeInherited
Fly Anatomy (FA)nerve0.003706InformativeInherited
Fly Anatomy (FA)adult procephalic segment0.006924InformativeInherited
Fly Anatomy (FA)presumptive embryonic/larval system0.007752InformativeInherited
Fly Anatomy (FA)dorsal closure embryo0.01144InformativeInherited
Fly Anatomy (FA)chemosensory system0.01583InformativeInherited
Fly Anatomy (FA)tract0.1037InformativeInherited
Fly Anatomy (FA)integumentary specialisation0.1438InformativeInherited
Fly Anatomy (FA)adult head sensillum0.1575InformativeInherited
Fly Anatomy (FA)brain0.2005InformativeInherited
Fly Anatomy (FA)somatic stem cell0.23InformativeInherited
Fly Anatomy (FA)leg0.2736InformativeInherited
Fly Anatomy (FA)adult central nervous system0.3885InformativeInherited
Fly Anatomy (FA)sensory organ cell0.4009InformativeInherited
Fly Anatomy (FA)eye0.4987InformativeInherited
Fly Anatomy (FA)embryonic/larval peripheral nervous system0.5308InformativeInherited
Fly Anatomy (FA)optic lobe neuron0.6404InformativeInherited
Fly Anatomy (FA)photoreceptor cell0.6934InformativeInherited
Fly Anatomy (FA)wing blade0.7661InformativeInherited
Fly Anatomy (FA)chaeta0.7686InformativeInherited
Fly Anatomy (FA)histaminergic neuron0.8251InformativeInherited
Fly Anatomy (FA)cuticle0.8274InformativeInherited
Fly Anatomy (FA)anatomical space0.8772InformativeInherited
Fly Anatomy (FA)labral segment0.898InformativeInherited
Fly Anatomy (FA)adult peripheral nervous system0.9004InformativeInherited
Fly Anatomy (FA)commissure0.00000187Highly InformativeDirect
Fly Anatomy (FA)head bristle0.00001268Highly InformativeDirect
Fly Anatomy (FA)U neuron0.00002432Highly InformativeDirect
Fly Anatomy (FA)embryonic head0.00004141Highly InformativeDirect
Fly Anatomy (FA)presumptive embryonic/larval central nervous system0.00004455Highly InformativeDirect
Fly Anatomy (FA)embryonic/larval sensillum0.00004579Highly InformativeDirect
Fly Anatomy (FA)ventral nervous system0.00007153Highly InformativeDirect
Fly Anatomy (FA)tagmatic subdivision of organ system0.0003201Highly InformativeDirect
Fly Anatomy (FA)maxillary palp olfactory receptor neuron0.0003227Highly InformativeDirect
Fly Anatomy (FA)larval abdominal segment 20.0006077Highly InformativeDirect
Fly Anatomy (FA)adult antennal lobe glomerulus0.001185Highly InformativeInherited
Fly Anatomy (FA)denticle belt0.00197Highly InformativeInherited
Fly Anatomy (FA)prothoracic segment0.01025Highly InformativeInherited
Fly Anatomy (FA)segment of antenna0.01734Highly InformativeInherited
Fly Anatomy (FA)embryonic/larval head sense organ0.03048Highly InformativeInherited
Fly Anatomy (FA)visceral mesoderm derivative0.04703Highly InformativeInherited
Fly Anatomy (FA)mushroom body extrinsic neuron0.07042Highly InformativeInherited
Fly Anatomy (FA)embryonic/larval hypodermal muscle0.1197Highly InformativeInherited
Fly Anatomy (FA)adult antennal sense organ0.3427Highly InformativeInherited
Fly Anatomy (FA)sensory cluster0.4039Highly InformativeInherited
Fly Anatomy (FA)wing vein0.9036Highly InformativeInherited

Document: FA annotation of SCOP domains

Zebrafish Anatomy (ZA)

(show details)
ZA termFDR (all)SDZA levelAnnotation (direct or inherited)
Zebrafish Anatomy (ZA)multi-tissue structure0.002284Least InformativeInherited
Zebrafish Anatomy (ZA)nervous system0.1199Least InformativeInherited
Zebrafish Anatomy (ZA)cell0.2126Least InformativeInherited
Zebrafish Anatomy (ZA)anatomical cluster0.5518Least InformativeInherited
Zebrafish Anatomy (ZA)cavitated compound organ0.9605Least InformativeInherited
Zebrafish Anatomy (ZA)portion of tissue0.0008921Moderately InformativeDirect
Zebrafish Anatomy (ZA)central nervous system0.2768Moderately InformativeInherited
Zebrafish Anatomy (ZA)diencephalon0.00006809InformativeDirect
Zebrafish Anatomy (ZA)digestive system0.1739InformativeInherited
Zebrafish Anatomy (ZA)pleuroperitoneal region0.9374InformativeInherited
Zebrafish Anatomy (ZA)endocrine system0.009286Highly InformativeInherited
Zebrafish Anatomy (ZA)telencephalon0.05207Highly InformativeInherited
Zebrafish Anatomy (ZA)embryonic structure0.07368Highly InformativeInherited

Document: ZA annotation of SCOP domains

Xenopus Anatomy (XA)

(show details)
XA termFDR (all)SDXA levelAnnotation (direct or inherited)
Xenopus ANatomical entity (XAN)embryo0.00000000009157Least InformativeDirect
Xenopus ANatomical entity (XAN)tissue0.0002707Least InformativeDirect
Xenopus ANatomical entity (XAN)nervous system0.002553Least InformativeInherited
Xenopus ANatomical entity (XAN)head0.381Least InformativeInherited
Xenopus ANatomical entity (XAN)urogenital system1Least InformativeInherited
Xenopus ANatomical entity (XAN)trunk1Least InformativeInherited
Xenopus ANatomical entity (XAN)anatomical cluster1Least InformativeInherited
Xenopus ANatomical entity (XAN)cavitated compound organ1Least InformativeInherited
Xenopus ANatomical entity (XAN)multi-tissue structure0Moderately InformativeDirect
Xenopus ANatomical entity (XAN)embryonic structure0Moderately InformativeDirect
Xenopus ANatomical entity (XAN)sensory system0Moderately InformativeDirect
Xenopus ANatomical entity (XAN)ectoderm0.006977Moderately InformativeInherited
Xenopus ANatomical entity (XAN)musculoskeletal system0.008341Moderately InformativeInherited
Xenopus ANatomical entity (XAN)brain0.1327Moderately InformativeInherited
Xenopus ANatomical entity (XAN)alimentary system1Moderately InformativeInherited
Xenopus ANatomical entity (XAN)viscus1Moderately InformativeInherited
Xenopus ANatomical entity (XAN)spinal cord0InformativeDirect
Xenopus ANatomical entity (XAN)neuroectoderm0InformativeDirect
Xenopus ANatomical entity (XAN)mesenchyme0InformativeDirect
Xenopus ANatomical entity (XAN)anatomical direction0InformativeDirect
Xenopus ANatomical entity (XAN)anatomical space0InformativeDirect
Xenopus ANatomical entity (XAN)neural tube0InformativeDirect
Xenopus ANatomical entity (XAN)pharyngeal region0InformativeDirect
Xenopus ANatomical entity (XAN)eye0.000000000002205InformativeDirect
Xenopus ANatomical entity (XAN)mesoderm0.000000000005439InformativeDirect
Xenopus ANatomical entity (XAN)peripheral nervous system0.0000000005104InformativeDirect
Xenopus ANatomical entity (XAN)cardiovascular system0.00000002037InformativeDirect
Xenopus ANatomical entity (XAN)epithelium0.0000002032InformativeDirect
Xenopus ANatomical entity (XAN)surface structure0.00000272InformativeDirect
Xenopus ANatomical entity (XAN)notochord0.00004845InformativeDirect
Xenopus ANatomical entity (XAN)skeletal system0.04574InformativeInherited
Xenopus ANatomical entity (XAN)vestibuloauditory system0.04622InformativeInherited
Xenopus ANatomical entity (XAN)urinary system0.6811InformativeInherited
Xenopus ANatomical entity (XAN)tail0.9114InformativeInherited
Xenopus ANatomical entity (XAN)endocrine system1InformativeInherited
Xenopus ANatomical entity (XAN)limb1InformativeInherited
Xenopus ANatomical entity (XAN)solid compound organ1InformativeInherited
Xenopus ANatomical entity (XAN)hindbrain0Highly InformativeDirect
Xenopus ANatomical entity (XAN)chordal neural plate0Highly InformativeDirect
Xenopus ANatomical entity (XAN)presumptive midbrain-hindbrain boundary0Highly InformativeDirect
Xenopus ANatomical entity (XAN)forebrain5.634e-16Highly InformativeDirect
Xenopus ANatomical entity (XAN)midbrain0.000000000000001126Highly InformativeDirect
Xenopus ANatomical entity (XAN)anterior neural fold0.00000000000004163Highly InformativeDirect
Xenopus ANatomical entity (XAN)neuron0.0000000000005985Highly InformativeDirect
Xenopus ANatomical entity (XAN)head mesenchyme0.000000000001732Highly InformativeDirect
Xenopus ANatomical entity (XAN)cranial neural crest0.000000000007737Highly InformativeDirect
Xenopus ANatomical entity (XAN)pronephric tubule0.00000000001277Highly InformativeDirect
Xenopus ANatomical entity (XAN)neural plate border0.00000000005962Highly InformativeDirect
Xenopus ANatomical entity (XAN)foregut0.0000000001742Highly InformativeDirect
Xenopus ANatomical entity (XAN)anterior neural ridge0.0000000002156Highly InformativeDirect
Xenopus ANatomical entity (XAN)limb bud0.000000007519Highly InformativeDirect
Xenopus ANatomical entity (XAN)fin0.000000009269Highly InformativeDirect
Xenopus ANatomical entity (XAN)hindgut0.00000002257Highly InformativeDirect
Xenopus ANatomical entity (XAN)anatomical line0.00000002697Highly InformativeDirect
Xenopus ANatomical entity (XAN)retinal inner nuclear layer0.000000408Highly InformativeDirect
Xenopus ANatomical entity (XAN)involuted dorsal mesoderm0.0000006878Highly InformativeDirect
Xenopus ANatomical entity (XAN)blastema0.000001082Highly InformativeDirect
Xenopus ANatomical entity (XAN)optic field0.00000136Highly InformativeDirect
Xenopus ANatomical entity (XAN)cranial nerve0.000001617Highly InformativeDirect
Xenopus ANatomical entity (XAN)neural groove0.000005796Highly InformativeDirect
Xenopus ANatomical entity (XAN)presomitic mesoderm0.000009011Highly InformativeDirect
Xenopus ANatomical entity (XAN)primordium0.000009203Highly InformativeDirect
Xenopus ANatomical entity (XAN)ganglion0.00003166Highly InformativeDirect
Xenopus ANatomical entity (XAN)tail bud0.00008022Highly InformativeDirect
Xenopus ANatomical entity (XAN)retinal ganglion cell layer0.0001549Highly InformativeDirect
Xenopus ANatomical entity (XAN)intersomitic region0.0005876Highly InformativeDirect
Xenopus ANatomical entity (XAN)circulatory system0.0008003Highly InformativeDirect
Xenopus ANatomical entity (XAN)archenteron0.0211Highly InformativeInherited
Xenopus ANatomical entity (XAN)olfactory system0.04148Highly InformativeInherited
Xenopus ANatomical entity (XAN)neurogenic placode0.4856Highly InformativeInherited
Xenopus ANatomical entity (XAN)splanchnocranium0.8771Highly InformativeInherited
Xenopus ANatomical entity (XAN)skeletal tissue1Highly InformativeInherited
Xenopus DEvelopment stage (XDE)post-embryonic stage1Least InformativeInherited
Xenopus DEvelopment stage (XDE)embryonic stage5.563e-16Moderately InformativeDirect
Xenopus DEvelopment stage (XDE)tailbud stage1InformativeInherited
Xenopus DEvelopment stage (XDE)adult frog stage0.0000007003Highly InformativeDirect
Xenopus DEvelopment stage (XDE)premetamorphosis stage0.005601Highly InformativeInherited
Xenopus DEvelopment stage (XDE)gastrula stage0.06423Highly InformativeInherited

Document: XA annotation of SCOP domains

Arabidopsis Plant Ontology (AP)

(show details)
AP termFDR (all)SDAP levelAnnotation (direct or inherited)
Plant ANatomical entity (PAN)shoot apex0.06058Least InformativeInherited
Plant ANatomical entity (PAN)seed0.06646Least InformativeInherited
Plant ANatomical entity (PAN)portion of meristem tissue0.3056Least InformativeInherited
Plant ANatomical entity (PAN)vascular leaf0.339Least InformativeInherited
Plant ANatomical entity (PAN)megasporophyll0.6493Least InformativeInherited
Plant ANatomical entity (PAN)root1Least InformativeInherited
Plant ANatomical entity (PAN)microsporophyll1Least InformativeInherited
Plant ANatomical entity (PAN)androecium1Least InformativeInherited
Plant ANatomical entity (PAN)gynoecium1Least InformativeInherited
Plant ANatomical entity (PAN)stalk1Least InformativeInherited
Plant ANatomical entity (PAN)sporangium1Least InformativeInherited
Plant ANatomical entity (PAN)fruit0.0000000000985InformativeDirect
Plant ANatomical entity (PAN)root tip0.00000000172InformativeDirect
Plant ANatomical entity (PAN)portion of ground tissue0.00000005718InformativeDirect
Plant ANatomical entity (PAN)vascular system0.00004436InformativeDirect
Plant ANatomical entity (PAN)shoot meristem0Highly InformativeDirect
Plant ANatomical entity (PAN)apical meristem0Highly InformativeDirect
Plant ANatomical entity (PAN)vegetative shoot apex0.0000000000005581Highly InformativeDirect
Plant ANatomical entity (PAN)phyllome primordium0.00000000001989Highly InformativeDirect
Plant ANatomical entity (PAN)plant ovule0.0000000001787Highly InformativeDirect
Plant ANatomical entity (PAN)primary root0.000000009909Highly InformativeDirect
Plant ANatomical entity (PAN)plant axis elongation zone0.0000008839Highly InformativeDirect
Plant ANatomical entity (PAN)filament0.0002885Highly InformativeDirect
Plant ANatomical entity (PAN)trichome0.000415Highly InformativeDirect
Plant ANatomical entity (PAN)stele0.001098Highly InformativeInherited
Plant ANatomical entity (PAN)cortex0.291Highly InformativeInherited
Plant structure DEvelopment stage (PDE)seedling development stage0.000003301InformativeDirect

Document: AP annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEC levelAnnotation (direct or inherited)
Enzyme Commission (EC)Transferases0Least InformativeDirect
Enzyme Commission (EC)Acyltransferases0Moderately InformativeDirect
Enzyme Commission (EC)Transferring groups other than amino-acyl groups0InformativeDirect

Document: EC annotation of SCOP domains

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Internal database links

   
Superfamily level     Family level

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


   
Superfamily level     Family level

Alignments of sequences to 187 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Superfamily level

Browse and view proteins in genomes which have different domain combinations including a Homeodomain-like domain.


   
Superfamily level     Family level

Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Jump to [ Top of page · SCOP classification · Disease Ontology (DO) · Human Phenotype (HP) · Mouse Phenotype (MP) · Worm Phenotype (WP) · Fly Phenotype (FP) · Fly Anatomy (FA) · Zebrafish Anatomy (ZA) · Xenopus Anatomy (XA) · Arabidopsis Plant Ontology (AP) · Enzyme Commission (EC) · Internal database links ]