SUPERFAMILY 1.75 HMM library and genome assignments server

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ARID domain family

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   All alpha proteins [ 46456] (284)
Fold:   DNA/RNA-binding 3-helical bundle [ 46688] (14)
Superfamily:   ARID-like [ 46774]
Family:   ARID domain [ 46775] (4)


Family statistics
Genomes (167) Uniprot 2018_03 genome PDB chains (SCOP 1.75)
Domains 754 2,357 5
Proteins 754 2,356 5


Human Phenotype (HP)

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show details)
HP termFDR (all)SDHP levelAnnotation (direct or inherited)
Phenotypic Abnormality (PA)Abnormality of the genitourinary system0Least InformativeDirect
Phenotypic Abnormality (PA)Abnormality of the musculature0.0736Least InformativeInherited
Phenotypic Abnormality (PA)Abnormality of the face0.08579Least InformativeInherited
Phenotypic Abnormality (PA)Abnormality of nervous system morphology0.09129Least InformativeInherited
Phenotypic Abnormality (PA)Abnormality of skeletal morphology0.09924Least InformativeInherited
Phenotypic Abnormality (PA)Abnormality of the eye0.1004Least InformativeInherited
Phenotypic Abnormality (PA)Abnormality of limbs0.1124Least InformativeInherited
Phenotypic Abnormality (PA)Abnormality of nervous system physiology0.2166Least InformativeInherited
Phenotypic Abnormality (PA)Abnormality of the integument0.2184Least InformativeInherited
Phenotypic Abnormality (PA)Abnormality of the cardiovascular system0.225Least InformativeInherited
Phenotypic Abnormality (PA)Abnormal ocular adnexa morphology0.002818Moderately InformativeInherited
Phenotypic Abnormality (PA)Abnormality of skull size0.003095Moderately InformativeInherited
Phenotypic Abnormality (PA)Aplasia/Hypoplasia involving the central nervous system0.005306Moderately InformativeInherited
Phenotypic Abnormality (PA)Abnormality of the cerebrum0.008939Moderately InformativeInherited
Phenotypic Abnormality (PA)Neurodevelopmental delay0.01741Moderately InformativeInherited
Phenotypic Abnormality (PA)Abnormality of the ear0.02247Moderately InformativeInherited
Phenotypic Abnormality (PA)Abnormality of skin adnexa morphology0.02385Moderately InformativeInherited
Phenotypic Abnormality (PA)Abnormality of the hand0.02707Moderately InformativeInherited
Phenotypic Abnormality (PA)Abnormal joint morphology0.03353Moderately InformativeInherited
Phenotypic Abnormality (PA)Abnormality of limb bone morphology0.03685Moderately InformativeInherited
Phenotypic Abnormality (PA)Abnormal eye physiology0.03915Moderately InformativeInherited
Phenotypic Abnormality (PA)Abnormality of the lower limb0.04225Moderately InformativeInherited
Phenotypic Abnormality (PA)Abnormality of skeletal physiology0.08157Moderately InformativeInherited
Phenotypic Abnormality (PA)Abnormal skeletal muscle morphology0.2052Moderately InformativeInherited
Phenotypic Abnormality (PA)Abnormality of the upper urinary tract0.345Moderately InformativeInherited
Phenotypic Abnormality (PA)Abnormality of the vertebral column0.3923Moderately InformativeInherited
Phenotypic Abnormality (PA)Abnormal reproductive system morphology0.641Moderately InformativeInherited
Phenotypic Abnormality (PA)Abnormal oral cavity morphology1Moderately InformativeInherited
Phenotypic Abnormality (PA)Abnormality of the palm0.0001127InformativeDirect
Phenotypic Abnormality (PA)Abnormal conjugate eye movement0.0004232InformativeDirect
Phenotypic Abnormality (PA)Abnormal lip morphology0.000541InformativeDirect
Phenotypic Abnormality (PA)Abnormality of the outer ear0.0008026InformativeDirect
Phenotypic Abnormality (PA)Abnormality of male external genitalia0.0008575InformativeDirect
Phenotypic Abnormality (PA)Microcephaly0.0008575InformativeDirect
Phenotypic Abnormality (PA)Aplasia/hypoplasia involving bones of the extremities0.001307InformativeInherited
Phenotypic Abnormality (PA)Abnormal finger phalanx morphology0.001402InformativeInherited
Phenotypic Abnormality (PA)Abnormal lower limb bone morphology0.00155InformativeInherited
Phenotypic Abnormality (PA)Abnormal hair quantity0.001565InformativeInherited
Phenotypic Abnormality (PA)Abnormality of the nose0.0066InformativeInherited
Phenotypic Abnormality (PA)Regional abnormality of skin0.007676InformativeInherited
Phenotypic Abnormality (PA)Vascular skin abnormality0.01113InformativeInherited
Phenotypic Abnormality (PA)Joint hypermobility0.02769InformativeInherited
Phenotypic Abnormality (PA)Abnormal renal morphology0.04702InformativeInherited
Phenotypic Abnormality (PA)Joint dislocation0.05677InformativeInherited
Phenotypic Abnormality (PA)Abnormality of toe0.05928InformativeInherited
Phenotypic Abnormality (PA)Abnormality of the cerebral ventricles0.0857InformativeInherited
Phenotypic Abnormality (PA)Abnormality of the cerebral subcortex0.1068InformativeInherited
Phenotypic Abnormality (PA)Slow-growing hair0.000003115Highly InformativeDirect
Phenotypic Abnormality (PA)Abnormality of the 5th toe0.000003514Highly InformativeDirect
Phenotypic Abnormality (PA)Cutis marmorata0.00001922Highly InformativeDirect
Phenotypic Abnormality (PA)Spina bifida occulta0.00002731Highly InformativeDirect
Phenotypic Abnormality (PA)Aplasia/Hypoplasia of the phalanges of the hand0.00002751Highly InformativeDirect
Phenotypic Abnormality (PA)Upper extremity joint dislocation0.00004247Highly InformativeDirect
Phenotypic Abnormality (PA)Thick eyebrow0.00006302Highly InformativeDirect
Phenotypic Abnormality (PA)Lacrimation abnormality0.00007463Highly InformativeDirect
Phenotypic Abnormality (PA)Cryptorchidism0.00009619Highly InformativeDirect
Phenotypic Abnormality (PA)Aplasia/Hypoplasia of fingers0.0001077Highly InformativeDirect
Phenotypic Abnormality (PA)Abnormality of the phalanges of the toes0.0001129Highly InformativeDirect
Phenotypic Abnormality (PA)Delayed speech and language development0.0001187Highly InformativeDirect
Phenotypic Abnormality (PA)Abnormal toenail morphology0.0001227Highly InformativeDirect
Phenotypic Abnormality (PA)Abnormality of the diaphragm0.0001487Highly InformativeDirect
Phenotypic Abnormality (PA)Abnormality of the femoral neck0.0001516Highly InformativeDirect
Phenotypic Abnormality (PA)Abnormal hand morphology0.0001691Highly InformativeDirect
Phenotypic Abnormality (PA)Wide mouth0.0001991Highly InformativeDirect
Phenotypic Abnormality (PA)Hypoplasia of the corpus callosum0.0002053Highly InformativeDirect
Phenotypic Abnormality (PA)Dilatation of the renal pelvis0.0002911Highly InformativeDirect
Phenotypic Abnormality (PA)Abnormal fingernail morphology0.0003512Highly InformativeDirect
Phenotypic Abnormality (PA)Aplasia/Hypoplasia of the cerebellar vermis0.0003861Highly InformativeDirect
Phenotypic Abnormality (PA)Aplasia/Hypoplasia of the nails0.0004464Highly InformativeDirect
Phenotypic Abnormality (PA)Abnormality of the nasal bridge0.0004718Highly InformativeDirect
Phenotypic Abnormality (PA)Abnormal dermatoglyphics0.0006886Highly InformativeDirect
Phenotypic Abnormality (PA)Short digit0.0009289Highly InformativeDirect
Phenotypic Abnormality (PA)Abnormality of the knee0.002312Highly InformativeInherited
Phenotypic Abnormality (PA)Ventriculomegaly0.009471Highly InformativeInherited
Phenotypic Abnormality (PA)Aplasia/Hypoplasia of toe0.01357Highly InformativeInherited
Phenotypic Abnormality (PA)Abnormal eyelash morphology0.01381Highly InformativeInherited
Phenotypic Abnormality (PA)Abnormal 5th finger morphology0.06183Highly InformativeInherited
Phenotypic Abnormality (PA)Agenesis of corpus callosum0.09083Highly InformativeInherited
Phenotypic Abnormality (PA)Abnormality of the external nose0.128Highly InformativeInherited
Phenotypic Abnormality (PA)Abnormality of the elbow0.1429Highly InformativeInherited

Document: HP annotation of SCOP domains

Mouse Phenotype (MP)

(show details)
MP termFDR (all)SDMP levelAnnotation (direct or inherited)
Mammalian Phenotype (MP)hematopoietic system phenotype0.003989Least InformativeInherited
Mammalian Phenotype (MP)abnormal hematopoietic stem cell morphology0.0002416Highly InformativeDirect

Document: MP annotation of SCOP domains

Worm Phenotype (WP)

(show details)
WP termFDR (all)SDWP levelAnnotation (direct or inherited)
Worm Phenotype (WP)slow growth0Least InformativeDirect
Worm Phenotype (WP)larval lethal0Least InformativeDirect
Worm Phenotype (WP)larval arrest0Least InformativeDirect
Worm Phenotype (WP)progeny variant0Least InformativeDirect
Worm Phenotype (WP)organism behavior variant0.006058Least InformativeInherited
Worm Phenotype (WP)organism environmental stimulus response variant0.006782Least InformativeInherited
Worm Phenotype (WP)organism stress response variant0.000338Moderately InformativeDirect
Worm Phenotype (WP)organism UV response variant0.000000000889Highly InformativeDirect

Document: WP annotation of SCOP domains

Fly Phenotype (FP)

(show details)
FP termFDR (all)SDFP levelAnnotation (direct or inherited)
Fly Phenotype (FP)increased mortality0Least InformativeDirect
Fly Phenotype (FP)modifier of variegation0.00003999InformativeDirect
Fly Phenotype (FP)some die during pupal stage0.00006327Highly InformativeDirect

Document: FP annotation of SCOP domains

Fly Anatomy (FA)

(show details)
FA termFDR (all)SDFA levelAnnotation (direct or inherited)
Fly Anatomy (FA)tagma0Least InformativeDirect
Fly Anatomy (FA)segment0Least InformativeDirect
Fly Anatomy (FA)adult0Least InformativeDirect
Fly Anatomy (FA)organ system subdivision0Least InformativeDirect

Document: FA annotation of SCOP domains

Xenopus Anatomy (XA)

(show details)
XA termFDR (all)SDXA levelAnnotation (direct or inherited)
Xenopus ANatomical entity (XAN)nervous system0Least InformativeDirect
Xenopus ANatomical entity (XAN)head0Least InformativeDirect
Xenopus ANatomical entity (XAN)cavitated compound organ0Least InformativeDirect
Xenopus ANatomical entity (XAN)embryo0.08654Least InformativeInherited
Xenopus ANatomical entity (XAN)tissue0.101Least InformativeInherited
Xenopus ANatomical entity (XAN)urogenital system0.1516Least InformativeInherited
Xenopus ANatomical entity (XAN)trunk0.2697Least InformativeInherited
Xenopus ANatomical entity (XAN)germ cell0.0007061Moderately InformativeDirect
Xenopus ANatomical entity (XAN)multi-tissue structure0.01267Moderately InformativeInherited
Xenopus ANatomical entity (XAN)anatomical space0.01187InformativeInherited
Xenopus ANatomical entity (XAN)urinary system0.02121InformativeInherited
Xenopus ANatomical entity (XAN)pronephric tubule0.0005629Highly InformativeDirect

Document: XA annotation of SCOP domains

Arabidopsis Plant Ontology (AP)

(show details)
AP termFDR (all)SDAP levelAnnotation (direct or inherited)
Plant ANatomical entity (PAN)seed0Least InformativeDirect
Plant ANatomical entity (PAN)microsporophyll0Least InformativeDirect
Plant structure DEvelopment stage (PDE)E expanded cotyledon stage0Least InformativeDirect

Document: AP annotation of SCOP domains

Jump to [ Top of page · SCOP classification · Human Phenotype (HP) · Mouse Phenotype (MP) · Worm Phenotype (WP) · Fly Phenotype (FP) · Fly Anatomy (FA) · Xenopus Anatomy (XA) · Arabidopsis Plant Ontology (AP) ]

Internal database links

   
Superfamily level     Family level

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


   
Superfamily level     Family level

Alignments of sequences to 10 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Superfamily level

Browse and view proteins in genomes which have different domain combinations including a ARID-like domain.


   
Superfamily level     Family level

Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Jump to [ Top of page · SCOP classification · Human Phenotype (HP) · Mouse Phenotype (MP) · Worm Phenotype (WP) · Fly Phenotype (FP) · Fly Anatomy (FA) · Xenopus Anatomy (XA) · Arabidopsis Plant Ontology (AP) · Internal database links ]