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RNA polymerase subunit RPB10 superfamily
SCOP classification
Superfamily statistics
Functional annotation
| General category | Information |
| Detailed category | RNA processing |
Function annotation of SCOP domain superfamilies
InterPro annotation
| Cross references | IPR000268 SSF46924 Protein matches |
| Abstract | In eukaryotes, there are three different forms of DNA-dependent RNA polymerases transcribing different sets of genes. Each class of RNA polymerase is an assemblage of ten to twelve different polypeptides. In archaebacteria, there is generally a single form of RNA polymerase which also consists of an oligomeric assemblage of 10 to 13 polypeptides.
Archaebacterial subunit N (gene rpoN) [ 7597027] is a small protein of about 8 kDa, it
is evolutionary related [8045907] to a 8.3 kDa component shared by all three forms of
eukaryotic RNA polymerases (gene RPB10 in yeast and POLR2J in mammals) as well
as to African swine fever virus protein CP80R [11831707].
There is a conserved region which is located at the
N-terminal extremity of these polymerase subunits; this region contains two
cysteines that binds a zinc ion [10841539]. |
InterPro database
PDBeMotif information about ligands, sequence and structure motifs
PDBeMotif resource
Jump to [ Top of page · SCOP classification · InterPro annotation · PDBeMotif links · Functional annotation ]
Internal database links
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Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry
out SCOP domain assignments to all genomes at the superfamily level.
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Alignments of sequences to 2 models
in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical
are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.
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Browse and view proteins in genomes which have
different domain combinations including a RNA polymerase subunit RPB10 domain.
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Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.
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Explore domain occurrence network where nodes represent genomes and edges are domain architectures (shared between genomes) containing the superfamily of interest.
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There are 2 hidden Markov models representing the RNA polymerase subunit RPB10 superfamily. Information on how the models are built, and plots showing hydrophobicity, match emmission probabilities and insertion/deletion probabilities can be inspected.
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Jump to [ Top of page · SCOP classification · InterPro annotation · PDBeMotif links · Functional annotation · Internal database links ]
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