SUPERFAMILY 1.73 HMM library and genome assignments server


CRAL/TRIO N-terminal domain superfamily

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   All alpha proteins [ 46456] (258)
Fold:   RuvA C-terminal domain-like [ 46928] (9)
  3 helices; bundle, right-handed twist
Superfamily:   CRAL/TRIO N-terminal domain [ 46938]
Families:   CRAL/TRIO N-terminal domain [ 46939] (3)


Superfamily statistics
Genomes (257) UniProt 15.0 PDB chains (SCOP 1.73)
Domains 2,644 1,444 5
Proteins 2,638 1,440 5


Functional annotation
General category Processes_IC
Detailed category Phospholipid metabolism and transport

Function annotation of SCOP domain superfamilies
InterPro annotation
Cross references IPR011074 SSF46938 Protein matches
Abstract

This entry contains the phosphatidylinositol transfer protein, Sec14p, which catalyses the exchange of phosphatidylinositol and phosphatidylcholine between membrane bilayers in vitro [PubMed9461221]. Other related proteins include the retinaldehyde/retinal-binding proteins, which are functional components of the visual cycle, guanine nucleotide exchange factor, and alpha-tocopherol transfer protein, which enhances the transfer of ligand between separate membranes, as well as several hypothetical proteins.


InterPro database

PDBeMotif information about ligands, sequence and structure motifs
Cross references PDB entries
Ligand binding statistics
Nucleic-acid binding statistics
Occurrence of secondary structure elements
Occurrence of small 3D structural motifs

PDBeMotif resource

Jump to [ Top of page · SCOP classification · InterPro annotation · PDBeMotif links · Functional annotation ]

Internal database links

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


Alignments of sequences to 3 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Browse and view proteins in genomes which have different domain combinations including a CRAL/TRIO N-terminal domain domain.


Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Explore domain occurrence network where nodes represent genomes and edges are domain architectures (shared between genomes) containing the superfamily of interest.

There are 3 hidden Markov models representing the CRAL/TRIO N-terminal domain superfamily. Information on how the models are built, and plots showing hydrophobicity, match emmission probabilities and insertion/deletion probabilities can be inspected.


Jump to [ Top of page · SCOP classification · InterPro annotation · PDBeMotif links · Functional annotation · Internal database links ]