SUPERFAMILY 1.75 HMM library and genome assignments server

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Nucleosome core histones family

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   All alpha proteins [ 46456] (284)
Fold:   Histone-fold [ 47112]
Superfamily:   Histone-fold [ 47113] (4)
Family:   Nucleosome core histones [ 47114] (5)

Family statistics
Genomes (506) Uniprot 2018_03 genome PDB chains (SCOP 1.75)
Domains 15,422 50,897 62
Proteins 15,342 50,583 61

Worm Phenotype (WP)

show details)
WP termFDR (all)SDWP levelAnnotation (direct or inherited)
Worm Phenotype (WP)cell physiology variant0.00000000000002425Least InformativeDirect
Worm Phenotype (WP)blast cell physiology variant0.00000000000002425Least InformativeDirect
Worm Phenotype (WP)cell morphology variant0.000000000001105Least InformativeDirect
Worm Phenotype (WP)organism behavior variant0.0000002952Least InformativeDirect
Worm Phenotype (WP)organism metabolism processing variant0.000006504Least InformativeDirect
Worm Phenotype (WP)cell development variant0.2789Least InformativeInherited
Worm Phenotype (WP)cell homeostasis metabolism variant0Moderately InformativeDirect
Worm Phenotype (WP)cell division variant0Moderately InformativeDirect
Worm Phenotype (WP)early embryonic lethal0Moderately InformativeDirect
Worm Phenotype (WP)germ cell development variant0.000301Moderately InformativeDirect
Worm Phenotype (WP)pattern of transgene expression variant0.0005048Moderately InformativeDirect
Worm Phenotype (WP)organ system development variant0.05445Moderately InformativeInherited
Worm Phenotype (WP)reproductive system morphology variant0.07162Moderately InformativeInherited
Worm Phenotype (WP)body region morphology variant0.4485Moderately InformativeInherited
Worm Phenotype (WP)organism segment morphology variant0.4485Moderately InformativeInherited
Worm Phenotype (WP)developmental morphology variant0.4494Moderately InformativeInherited
Worm Phenotype (WP)cell death variant0.4505Moderately InformativeInherited
Worm Phenotype (WP)adult body morphology variant0.4506Moderately InformativeInherited
Worm Phenotype (WP)body morphology variant0.4712Moderately InformativeInherited
Worm Phenotype (WP)germ cell differentiation variant1Moderately InformativeInherited
Worm Phenotype (WP)cytokinesis variant emb0InformativeDirect
Worm Phenotype (WP)vesicle morphology variant0InformativeDirect
Worm Phenotype (WP)cell component localization variant0InformativeDirect
Worm Phenotype (WP)avoids bacterial lawn6.242e-16InformativeDirect
Worm Phenotype (WP)meiotic chromosome organization variant0.0000000000006497InformativeDirect
Worm Phenotype (WP)organism pathogen response variant0.00000000009498InformativeDirect
Worm Phenotype (WP)dauer arrest variant0.000000005635InformativeDirect
Worm Phenotype (WP)alimentary system development variant0.00000006815InformativeDirect
Worm Phenotype (WP)vulva morphology variant0.0004938InformativeDirect
Worm Phenotype (WP)mitosis variant0.0207InformativeInherited
Worm Phenotype (WP)diplotene progression during oogenesis variant0.2278InformativeInherited
Worm Phenotype (WP)organism stress response variant1InformativeInherited
Worm Phenotype (WP)lysosome-related organelle morphology variant0Highly InformativeDirect
Worm Phenotype (WP)RAB-11 recycling endosome localization variant0Highly InformativeDirect
Worm Phenotype (WP)no induction of antimicrobial peptide expression after infection0Highly InformativeDirect
Worm Phenotype (WP)embryonic arrest0.0000000002288Highly InformativeDirect
Worm Phenotype (WP)chromosome condensation variant0.000002949Highly InformativeDirect
Worm Phenotype (WP)alimentary system morphology variant0.09669Highly InformativeInherited

Document: WP annotation of SCOP domains

Yeast Phenotype (YP)

(show details)
YP termFDR (all)SDYP levelAnnotation (direct or inherited)
Yeast Phenotype (YP)development0.01979Moderately InformativeInherited
Yeast Phenotype (YP)cell cycle progression0.00006802InformativeDirect
Yeast Phenotype (YP)cell cycle progression in G2 phase0.0000000004388Highly InformativeDirect
Yeast Phenotype (YP)budding index0.000000003121Highly InformativeDirect

Document: YP annotation of SCOP domains

Fly Anatomy (FA)

(show details)
FA termFDR (all)SDFA levelAnnotation (direct or inherited)
Fly Anatomy (FA)larva0Least InformativeDirect

Document: FA annotation of SCOP domains

Xenopus Anatomy (XA)

(show details) Document: XA annotation of SCOP domains

Arabidopsis Plant Ontology (AP)

(show details)
AP termFDR (all)SDAP levelAnnotation (direct or inherited)
Plant ANatomical entity (PAN)root0.3098Least InformativeInherited
Plant ANatomical entity (PAN)shoot apex0.3288Least InformativeInherited
Plant ANatomical entity (PAN)portion of meristem tissue0.753Least InformativeInherited
Plant ANatomical entity (PAN)root tip0.0006523InformativeDirect
Plant ANatomical entity (PAN)lateral root primordium0.0000003089Highly InformativeDirect
Plant ANatomical entity (PAN)lateral root0.0000005644Highly InformativeDirect
Plant ANatomical entity (PAN)shoot meristem0.00005496Highly InformativeDirect
Plant ANatomical entity (PAN)apical meristem0.000141Highly InformativeDirect
Plant structure DEvelopment stage (PDE)seedling development stage0.00000001105InformativeDirect

Document: AP annotation of SCOP domains

Jump to [ Top of page · SCOP classification · Worm Phenotype (WP) · Yeast Phenotype (YP) · Fly Anatomy (FA) · Xenopus Anatomy (XA) · Arabidopsis Plant Ontology (AP) ]

Internal database links

Superfamily level     Family level

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.

Superfamily level     Family level

Alignments of sequences to 46 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.

Superfamily level

Browse and view proteins in genomes which have different domain combinations including a Histone-fold domain.

Superfamily level     Family level

Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.

Jump to [ Top of page · SCOP classification · Worm Phenotype (WP) · Yeast Phenotype (YP) · Fly Anatomy (FA) · Xenopus Anatomy (XA) · Arabidopsis Plant Ontology (AP) · Internal database links ]