SUPERFAMILY 1.75 HMM library and genome assignments server

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Calmodulin-like family

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   All alpha proteins [ 46456] (284)
Fold:   EF Hand-like [ 47472] (4)
Superfamily:   EF-hand [ 47473] (11)
Family:   Calmodulin-like [ 47502] (23)


Family statistics
Genomes (510) Uniprot 2018_03 genome PDB chains (SCOP 1.75)
Domains 9,043 27,069 92
Proteins 9,027 27,017 92


Enzyme Commission (EC)

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show details)
EC termFDR (all)SDEO levelAnnotation (direct or inherited)
Enzyme Commission (EC)Oxidoreductases0.6008Least InformativeInherited
Enzyme Commission (EC)Protein-serine/threonine kinases0Moderately InformativeDirect
Enzyme Commission (EC)Transferring groups other than amino-acyl groups0.006783Moderately InformativeInherited
Enzyme Commission (EC)Non-specific serine/threonine protein kinase0.00008592InformativeDirect

Document: EC annotation of SCOP domains

Disease Ontology (DO)

(show details)
DO termFDR (all)SDDO levelAnnotation (direct or inherited)
Disease Ontology (DO)nervous system disease0.4835Least InformativeInherited
Disease Ontology (DO)epilepsy0.0006348InformativeDirect

Document: DO annotation of SCOP domains

Human Phenotype (HP)

(show details)
HP termFDR (all)SDHP levelAnnotation (direct or inherited)
Phenotypic Abnormality (PA)Abnormality of the cardiovascular system0.6305Least InformativeInherited
Phenotypic Abnormality (PA)Abnormal cardiovascular system physiology0.2945Moderately InformativeInherited
Phenotypic Abnormality (PA)Arrhythmia0.007566InformativeInherited
Phenotypic Abnormality (PA)Abnormal cardiac test0.0001465Highly InformativeDirect
Phenotypic Abnormality (PA)Syncope0.0007808Highly InformativeDirect
Phenotypic Abnormality (PA)Ventricular arrhythmia0.005066Highly InformativeInherited
Phenotypic Abnormality (PA)Tachycardia0.06159Highly InformativeInherited

Document: HP annotation of SCOP domains

Mouse Phenotype (MP)

(show details)
MP termFDR (all)SDMP levelAnnotation (direct or inherited)
Mammalian Phenotype (MP)nervous system phenotype0.2187Least InformativeInherited
Mammalian Phenotype (MP)abnormal somatic sensory system morphology0.07692Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal neuron morphology0.2303Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal eye morphology0.9507Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal retinal neuronal layer morphology0.07031InformativeInherited

Document: MP annotation of SCOP domains

Worm Phenotype (WP)

(show details)
WP termFDR (all)SDWP levelAnnotation (direct or inherited)
Worm Phenotype (WP)organism metabolism processing variant0.5376Least InformativeInherited
Worm Phenotype (WP)cell morphology variant0.6048Least InformativeInherited
Worm Phenotype (WP)protein protein interaction variant0.0000497Moderately InformativeDirect
Worm Phenotype (WP)cuticle morphology variant0.01498Highly InformativeInherited

Document: WP annotation of SCOP domains

Fly Phenotype (FP)

(show details) Document: FP annotation of SCOP domains

Fly Anatomy (FA)

(show details) Document: FA annotation of SCOP domains

Zebrafish Anatomy (ZA)

(show details) Document: ZA annotation of SCOP domains

Xenopus Anatomy (XA)

(show details)
XA termFDR (all)SDXA levelAnnotation (direct or inherited)
Xenopus ANatomical entity (XAN)anatomical cluster0.7Least InformativeInherited
Xenopus ANatomical entity (XAN)trunk0.9246Least InformativeInherited
Xenopus ANatomical entity (XAN)embryo0.9839Least InformativeInherited
Xenopus ANatomical entity (XAN)tissue1Least InformativeInherited
Xenopus ANatomical entity (XAN)cavitated compound organ1Least InformativeInherited
Xenopus ANatomical entity (XAN)multi-tissue structure0.7217Moderately InformativeInherited
Xenopus ANatomical entity (XAN)viscus0.8151Moderately InformativeInherited
Xenopus ANatomical entity (XAN)ectoderm1Moderately InformativeInherited
Xenopus ANatomical entity (XAN)cardiovascular system0.0121InformativeInherited
Xenopus ANatomical entity (XAN)epithelium0.06028InformativeInherited
Xenopus ANatomical entity (XAN)dermal system0.1373InformativeInherited
Xenopus ANatomical entity (XAN)surface structure0.4501InformativeInherited
Xenopus ANatomical entity (XAN)epithelial cell0.0007187Highly InformativeDirect
Xenopus ANatomical entity (XAN)ciliated cell0.001948Highly InformativeInherited
Xenopus ANatomical entity (XAN)epidermis0.3301Highly InformativeInherited

Document: XA annotation of SCOP domains

Arabidopsis Plant Ontology (AP)

(show details)
AP termFDR (all)SDAP levelAnnotation (direct or inherited)
Plant ANatomical entity (PAN)pollen tube cell0.00004258InformativeDirect

Document: AP annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEC levelAnnotation (direct or inherited)
Enzyme Commission (EC)Transferases0Least InformativeDirect
Enzyme Commission (EC)Oxidoreductases0.9723Least InformativeInherited
Enzyme Commission (EC)Acyltransferases1Moderately InformativeInherited
Enzyme Commission (EC)Protein-serine/threonine kinases0InformativeDirect
Enzyme Commission (EC)Transferring groups other than amino-acyl groups0.05745InformativeInherited

Document: EC annotation of SCOP domains

Jump to [ Top of page · SCOP classification · Enzyme Commission (EC) · Disease Ontology (DO) · Human Phenotype (HP) · Mouse Phenotype (MP) · Worm Phenotype (WP) · Fly Phenotype (FP) · Fly Anatomy (FA) · Zebrafish Anatomy (ZA) · Xenopus Anatomy (XA) · Arabidopsis Plant Ontology (AP) · Enzyme Commission (EC) ]

Internal database links

   
Superfamily level     Family level

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


   
Superfamily level     Family level

Alignments of sequences to 174 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Superfamily level

Browse and view proteins in genomes which have different domain combinations including a EF-hand domain.


   
Superfamily level     Family level

Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Jump to [ Top of page · SCOP classification · Enzyme Commission (EC) · Disease Ontology (DO) · Human Phenotype (HP) · Mouse Phenotype (MP) · Worm Phenotype (WP) · Fly Phenotype (FP) · Fly Anatomy (FA) · Zebrafish Anatomy (ZA) · Xenopus Anatomy (XA) · Arabidopsis Plant Ontology (AP) · Enzyme Commission (EC) · Internal database links ]