SUPERFAMILY 1.75 HMM library and genome assignments server

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Glutathione S-transferase (GST), C-terminal domain family

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   All alpha proteins [ 46456] (284)
Fold:   GST C-terminal domain-like [ 47615]
Superfamily:   GST C-terminal domain-like [ 47616] (2)
Family:   Glutathione S-transferase (GST), C-terminal domain [ 47617] (18)


Family statistics
Genomes (726) Uniprot 2018_03 genome PDB chains (SCOP 1.75)
Domains 5,152 13,810 102
Proteins 5,085 13,641 102


Enzyme Commission (EC)

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show details)
EC termFDR (all)SDEO levelAnnotation (direct or inherited)
Enzyme Commission (EC)Isomerases0.6021Least InformativeInherited
Enzyme Commission (EC)Lyases1Least InformativeInherited
Enzyme Commission (EC)Oxidoreductases1Least InformativeInherited
Enzyme Commission (EC)Intramolecular oxidoreductases0.3396Moderately InformativeInherited
Enzyme Commission (EC)Transferring alkyl or aryl groups, other than meth1Moderately InformativeInherited
Enzyme Commission (EC)Acting on a sulfur group of donors0.000007889InformativeDirect
Enzyme Commission (EC)Cis-trans Isomerases1InformativeInherited
Enzyme Commission (EC)Glutathione transferase0Highly InformativeDirect
Enzyme Commission (EC)Other intramolecular oxidoreductases0.000000000000001381Highly InformativeDirect

Document: EC annotation of SCOP domains

Disease Ontology (DO)

(show details)
DO termFDR (all)SDDO levelAnnotation (direct or inherited)
Disease Ontology (DO)hematopoietic system disease0.06715Moderately InformativeInherited
Disease Ontology (DO)gastrointestinal system disease0.4202Moderately InformativeInherited
Disease Ontology (DO)Barrett's esophagus0.0006684Highly InformativeDirect
Disease Ontology (DO)anemia0.0109Highly InformativeInherited

Document: DO annotation of SCOP domains

Human Phenotype (HP)

(show details)
HP termFDR (all)SDHP levelAnnotation (direct or inherited)
Phenotypic Abnormality (PA)Abnormality of nervous system morphology0.2023Least InformativeInherited

Document: HP annotation of SCOP domains

Worm Phenotype (WP)

(show details)
WP termFDR (all)SDWP levelAnnotation (direct or inherited)
Worm Phenotype (WP)organism environmental stimulus response variant0.003192Least InformativeInherited
Worm Phenotype (WP)organism metabolism processing variant0.3266Least InformativeInherited
Worm Phenotype (WP)organism stress response variant0.0005923Moderately InformativeDirect
Worm Phenotype (WP)chemical response variant0.9225Moderately InformativeInherited
Worm Phenotype (WP)metal response variant0.0008257InformativeDirect
Worm Phenotype (WP)chemical hypersensitive0.001476InformativeInherited
Worm Phenotype (WP)organism temperature response variant0.8054InformativeInherited
Worm Phenotype (WP)enzyme activity reduced0Highly InformativeDirect
Worm Phenotype (WP)cadmium hypersensitive0.0008538Highly InformativeDirect
Worm Phenotype (WP)organism heat response variant0.01475Highly InformativeInherited

Document: WP annotation of SCOP domains

Yeast Phenotype (YP)

(show details) Document: YP annotation of SCOP domains

Zebrafish Anatomy (ZA)

(show details) Document: ZA annotation of SCOP domains

Xenopus Anatomy (XA)

(show details)
XA termFDR (all)SDXA levelAnnotation (direct or inherited)
Xenopus ANatomical entity (XAN)tail region0.000359Moderately InformativeDirect
Xenopus ANatomical entity (XAN)dermal system0.00003724InformativeDirect
Xenopus ANatomical entity (XAN)surface structure0.0003364InformativeDirect
Xenopus DEvelopment stage (XDE)unspecified stage0.0006053Moderately InformativeDirect

Document: XA annotation of SCOP domains

Arabidopsis Plant Ontology (AP)

(show details)
AP termFDR (all)SDAP levelAnnotation (direct or inherited)
Plant ANatomical entity (PAN)vascular system0.0177InformativeInherited
Plant ANatomical entity (PAN)phloem0.0006081Highly InformativeDirect

Document: AP annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEC levelAnnotation (direct or inherited)
Enzyme Commission (EC)Transferases0Least InformativeDirect
Enzyme Commission (EC)Oxidoreductases1Least InformativeInherited
Enzyme Commission (EC)Isomerases0.3785Moderately InformativeInherited
Enzyme Commission (EC)Lyases1Moderately InformativeInherited
Enzyme Commission (EC)Transferring alkyl or aryl groups, other than methyl groups0InformativeDirect
Enzyme Commission (EC)Intramolecular oxidoreductases0.1936InformativeInherited
Enzyme Commission (EC)Cis-trans isomerases1Highly InformativeInherited

Document: EC annotation of SCOP domains

UniProtKB KeyWords (KW)

(show details)
KW termFDR (all)SDKW levelAnnotation (direct or inherited)
Post-translational modificationTransferase0.000000000000001172Moderately InformativeDirect
Post-translational modificationEye lens protein0InformativeDirect

Document: KW annotation of SCOP domains

Jump to [ Top of page · SCOP classification · Enzyme Commission (EC) · Disease Ontology (DO) · Human Phenotype (HP) · Worm Phenotype (WP) · Yeast Phenotype (YP) · Zebrafish Anatomy (ZA) · Xenopus Anatomy (XA) · Arabidopsis Plant Ontology (AP) · Enzyme Commission (EC) · UniProtKB KeyWords (KW) ]

Internal database links

   
Superfamily level     Family level

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


   
Superfamily level     Family level

Alignments of sequences to 146 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Superfamily level

Browse and view proteins in genomes which have different domain combinations including a GST C-terminal domain-like domain.


   
Superfamily level     Family level

Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Jump to [ Top of page · SCOP classification · Enzyme Commission (EC) · Disease Ontology (DO) · Human Phenotype (HP) · Worm Phenotype (WP) · Yeast Phenotype (YP) · Zebrafish Anatomy (ZA) · Xenopus Anatomy (XA) · Arabidopsis Plant Ontology (AP) · Enzyme Commission (EC) · UniProtKB KeyWords (KW) · Internal database links ]