SUPERFAMILY 1.75 HMM library and genome assignments server

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p53 tetramerization domain family

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   All alpha proteins [ 46456] (284)
Fold:   p53 tetramerization domain [ 47718]
Superfamily:   p53 tetramerization domain [ 47719]
Family:   p53 tetramerization domain [ 47720]


Family statistics
Genomes (0) Uniprot 2018_03 genome PDB chains (SCOP 1.75)
Domains 0 0 0
Proteins 0 0 0


Disease Ontology (DO)

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show details)
DO termFDR (all)SDDO levelAnnotation (direct or inherited)
Disease Ontology (DO)organ system cancer0Least InformativeDirect
Disease Ontology (DO)nervous system disease0Least InformativeDirect
Disease Ontology (DO)disease by infectious agent0Moderately InformativeDirect
Disease Ontology (DO)cell type cancer0Moderately InformativeDirect
Disease Ontology (DO)benign neoplasm0Moderately InformativeDirect
Disease Ontology (DO)disease of mental health0Moderately InformativeDirect
Disease Ontology (DO)hematologic cancer0Moderately InformativeDirect
Disease Ontology (DO)gastrointestinal system cancer0Moderately InformativeDirect
Disease Ontology (DO)genetic disease0Moderately InformativeDirect
Disease Ontology (DO)hematopoietic system disease0Moderately InformativeDirect
Disease Ontology (DO)gastrointestinal system disease0Moderately InformativeDirect
Disease Ontology (DO)cell type benign neoplasm0InformativeDirect
Disease Ontology (DO)lymphoblastic leukemia0InformativeDirect
Disease Ontology (DO)head and neck carcinoma0InformativeDirect
Disease Ontology (DO)endocrine gland cancer0InformativeDirect
Disease Ontology (DO)lung carcinoma0InformativeDirect
Disease Ontology (DO)hereditary breast ovarian cancer syndrome0InformativeDirect
Disease Ontology (DO)liver carcinoma0InformativeDirect
Disease Ontology (DO)substance dependence0InformativeDirect
Disease Ontology (DO)squamous cell carcinoma0Highly InformativeDirect
Disease Ontology (DO)melanoma0Highly InformativeDirect
Disease Ontology (DO)laryngeal carcinoma0Highly InformativeDirect
Disease Ontology (DO)adenocarcinoma0Highly InformativeDirect
Disease Ontology (DO)lung adenocarcinoma0Highly InformativeDirect
Disease Ontology (DO)progressive multifocal leukoencephalopathy0Highly InformativeDirect

Document: DO annotation of SCOP domains

Mouse Phenotype (MP)

(show details)
MP termFDR (all)SDMP levelAnnotation (direct or inherited)
Mammalian Phenotype (MP)abnormal homeostasis0Least InformativeDirect
Mammalian Phenotype (MP)growth/size/body region phenotype0Least InformativeDirect
Mammalian Phenotype (MP)endocrine/exocrine gland phenotype0Least InformativeDirect
Mammalian Phenotype (MP)cellular phenotype0Least InformativeDirect
Mammalian Phenotype (MP)cardiovascular system phenotype0Least InformativeDirect
Mammalian Phenotype (MP)immune system phenotype0Least InformativeDirect
Mammalian Phenotype (MP)mortality/aging0Least InformativeDirect
Mammalian Phenotype (MP)abnormal cell death0Moderately InformativeDirect
Mammalian Phenotype (MP)abnormal craniofacial morphology0Moderately InformativeDirect
Mammalian Phenotype (MP)abnormal head morphology0Moderately InformativeDirect
Mammalian Phenotype (MP)abnormal digestive system morphology0Moderately InformativeDirect
Mammalian Phenotype (MP)abnormal cardiovascular system physiology0Moderately InformativeDirect
Mammalian Phenotype (MP)abnormal inflammatory response0Moderately InformativeDirect
Mammalian Phenotype (MP)abnormal reproductive system physiology0Moderately InformativeDirect
Mammalian Phenotype (MP)neoplasm0Moderately InformativeDirect
Mammalian Phenotype (MP)prenatal lethality0Moderately InformativeDirect
Mammalian Phenotype (MP)abnormal eye morphology0Moderately InformativeDirect
Mammalian Phenotype (MP)abnormal axial skeleton morphology0Moderately InformativeDirect
Mammalian Phenotype (MP)abnormal reproductive system morphology0Moderately InformativeDirect
Mammalian Phenotype (MP)abnormal body size0Moderately InformativeDirect
Mammalian Phenotype (MP)respiratory system phenotype0Moderately InformativeDirect
Mammalian Phenotype (MP)abnormal body composition0Moderately InformativeDirect
Mammalian Phenotype (MP)abnormal skin adnexa morphology0Moderately InformativeDirect
Mammalian Phenotype (MP)lethality during fetal growth through weaning0Moderately InformativeDirect
Mammalian Phenotype (MP)abnormal behavior1Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal cartilage morphology0InformativeDirect
Mammalian Phenotype (MP)abnormal intestine morphology0InformativeDirect
Mammalian Phenotype (MP)abnormal mammary gland morphology0InformativeDirect
Mammalian Phenotype (MP)abnormal ovary morphology0InformativeDirect
Mammalian Phenotype (MP)decreased body size0InformativeDirect
Mammalian Phenotype (MP)abnormal fluid regulation0InformativeDirect
Mammalian Phenotype (MP)hemorrhage0InformativeDirect
Mammalian Phenotype (MP)increased malignant tumor incidence0InformativeDirect
Mammalian Phenotype (MP)premature death0InformativeDirect
Mammalian Phenotype (MP)abnormal voluntary movement0InformativeDirect
Mammalian Phenotype (MP)abnormal vertebral column morphology0InformativeDirect
Mammalian Phenotype (MP)increased gland tumor incidence0InformativeDirect
Mammalian Phenotype (MP)increased hemolymphoid system tumor incidence0InformativeDirect
Mammalian Phenotype (MP)altered tumor pathology0InformativeDirect
Mammalian Phenotype (MP)decreased total tissue mass0InformativeDirect
Mammalian Phenotype (MP)weight loss0Highly InformativeDirect
Mammalian Phenotype (MP)increased T cell derived lymphoma incidence0Highly InformativeDirect
Mammalian Phenotype (MP)increased leukemia incidence0Highly InformativeDirect
Mammalian Phenotype (MP)increased sarcoma incidence0Highly InformativeDirect
Mammalian Phenotype (MP)abnormal cell nucleus morphology0Highly InformativeDirect
Mammalian Phenotype (MP)premature aging0Highly InformativeDirect
Mammalian Phenotype (MP)abnormal intervertebral disk morphology0Highly InformativeDirect
Mammalian Phenotype (MP)decreased apoptosis0Highly InformativeDirect
Mammalian Phenotype (MP)decreased sensitivity to induced cell death0Highly InformativeDirect
Mammalian Phenotype (MP)increased adenocarcinoma incidence0Highly InformativeDirect
Mammalian Phenotype (MP)increased alimentary system tumor incidence0Highly InformativeDirect
Mammalian Phenotype (MP)increased respiratory system tumor incidence0Highly InformativeDirect
Mammalian Phenotype (MP)increased mammary gland tumor incidence0Highly InformativeDirect

Document: MP annotation of SCOP domains

Zebrafish Anatomy (ZA)

(show details)
ZA termFDR (all)SDZA levelAnnotation (direct or inherited)
Zebrafish Anatomy (ZA)organism subdivision0Least InformativeDirect

Document: ZA annotation of SCOP domains

Xenopus Anatomy (XA)

(show details) Document: XA annotation of SCOP domains

Jump to [ Top of page · SCOP classification · Disease Ontology (DO) · Mouse Phenotype (MP) · Zebrafish Anatomy (ZA) · Xenopus Anatomy (XA) ]

Internal database links

   
Superfamily level     Family level

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


   
Superfamily level     Family level

Alignments of sequences to 7 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Superfamily level

Browse and view proteins in genomes which have different domain combinations including a p53 tetramerization domain domain.


   
Superfamily level     Family level

Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Jump to [ Top of page · SCOP classification · Disease Ontology (DO) · Mouse Phenotype (MP) · Zebrafish Anatomy (ZA) · Xenopus Anatomy (XA) · Internal database links ]