SUPERFAMILY 1.75 HMM library and genome assignments server

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Ephrin receptor ligand binding domain family

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   All beta proteins [ 48724] (174)
Fold:   Galactose-binding domain-like [ 49784]
Superfamily:   Galactose-binding domain-like [ 49785] (32)
Family:   Ephrin receptor ligand binding domain [ 49800] (2)


Family statistics
Genomes (112) Uniprot 2018_03 genome PDB chains (SCOP 1.75)
Domains 1,303 3,063 5
Proteins 1,303 3,062 5


Enzyme Commission (EC)

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show details)
EC termFDR (all)SDEO levelAnnotation (direct or inherited)
Enzyme Commission (EC)Receptor protein-tyrosine kinase0InformativeDirect

Document: EC annotation of SCOP domains

Disease Ontology (DO)

(show details)
DO termFDR (all)SDDO levelAnnotation (direct or inherited)
Disease Ontology (DO)organ system cancer0Least InformativeDirect
Disease Ontology (DO)cell type cancer0.003064Moderately InformativeInherited
Disease Ontology (DO)gastrointestinal system cancer0.04092Moderately InformativeInherited
Disease Ontology (DO)breast carcinoma0.00005558InformativeDirect
Disease Ontology (DO)large intestine cancer0.000139InformativeDirect
Disease Ontology (DO)endocrine gland cancer0.001888InformativeInherited
Disease Ontology (DO)pancreatic ductal adenocarcinoma0.0000001807Highly InformativeDirect
Disease Ontology (DO)invasive ductal carcinoma0.0000006899Highly InformativeDirect

Document: DO annotation of SCOP domains

Mouse Phenotype (MP)

(show details)
MP termFDR (all)SDMP levelAnnotation (direct or inherited)
Mammalian Phenotype (MP)nervous system phenotype0.09697Least InformativeInherited
Mammalian Phenotype (MP)cellular phenotype0.4435Least InformativeInherited
Mammalian Phenotype (MP)abnormal nervous system development0.01197Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal neuron morphology0.0523Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal brain morphology0.5151Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal nervous system tract morphology0.0001173InformativeDirect
Mammalian Phenotype (MP)abnormal innervation0.000367InformativeDirect
Mammalian Phenotype (MP)abnormal brain white matter morphology0.0005095InformativeDirect
Mammalian Phenotype (MP)abnormal neuron differentiation0.003737InformativeInherited
Mammalian Phenotype (MP)abnormal cerebral hemisphere morphology0.01329InformativeInherited
Mammalian Phenotype (MP)abnormal neurite morphology0.01383InformativeInherited
Mammalian Phenotype (MP)abnormal axon guidance0.00000005405Highly InformativeDirect
Mammalian Phenotype (MP)abnormal axon morphology0.00001586Highly InformativeDirect
Mammalian Phenotype (MP)abnormal dorsal telencephalic commissure morphology0.559Highly InformativeInherited

Document: MP annotation of SCOP domains

Xenopus Anatomy (XA)

(show details)
XA termFDR (all)SDXA levelAnnotation (direct or inherited)
Xenopus ANatomical entity (XAN)nervous system0Least InformativeDirect
Xenopus ANatomical entity (XAN)head0Least InformativeDirect
Xenopus ANatomical entity (XAN)cavitated compound organ0Least InformativeDirect
Xenopus ANatomical entity (XAN)embryo0.5156Least InformativeInherited
Xenopus ANatomical entity (XAN)tissue0.8498Least InformativeInherited
Xenopus ANatomical entity (XAN)brain0Moderately InformativeDirect
Xenopus ANatomical entity (XAN)ectoderm0.2309Moderately InformativeInherited
Xenopus ANatomical entity (XAN)neuroectoderm0.09428InformativeInherited
Xenopus ANatomical entity (XAN)cranial neural crest0.002029Highly InformativeInherited

Document: XA annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEC levelAnnotation (direct or inherited)
Enzyme Commission (EC)Transferases0Least InformativeDirect
Enzyme Commission (EC)Receptor protein-tyrosine kinase0Highly InformativeDirect

Document: EC annotation of SCOP domains

Jump to [ Top of page · SCOP classification · Enzyme Commission (EC) · Disease Ontology (DO) · Mouse Phenotype (MP) · Xenopus Anatomy (XA) · Enzyme Commission (EC) ]

Internal database links

   
Superfamily level     Family level

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


   
Superfamily level     Family level

Alignments of sequences to 111 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Superfamily level

Browse and view proteins in genomes which have different domain combinations including a Galactose-binding domain-like domain.


   
Superfamily level     Family level

Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Jump to [ Top of page · SCOP classification · Enzyme Commission (EC) · Disease Ontology (DO) · Mouse Phenotype (MP) · Xenopus Anatomy (XA) · Enzyme Commission (EC) · Internal database links ]