SUPERFAMILY 1.75 HMM library and genome assignments server

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Laminin G-like module family

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   All beta proteins [ 48724] (174)
Fold:   Concanavalin A-like lectins/glucanases [ 49898]
Superfamily:   Concanavalin A-like lectins/glucanases [ 49899] (25)
Family:   Laminin G-like module [ 49944] (6)

Family statistics
Genomes (96) Uniprot 2018_03 genome PDB chains (SCOP 1.75)
Domains 1,194 3,714 22
Proteins 949 3,113 19

Human Phenotype (HP)

show details)
HP termFDR (all)SDHP levelAnnotation (direct or inherited)
Phenotypic Abnormality (PA)Abnormality of the eye0.01597Least InformativeInherited
Phenotypic Abnormality (PA)Abnormal eye physiology0.1304Moderately InformativeInherited
Phenotypic Abnormality (PA)Abnormality of the voice0.03392InformativeInherited
Phenotypic Abnormality (PA)Abnormal fundus morphology0.2116InformativeInherited
Phenotypic Abnormality (PA)Weak cry0.00011Highly InformativeDirect
Phenotypic Abnormality (PA)Abnormality of retinal pigmentation0.1267Highly InformativeInherited

Document: HP annotation of SCOP domains

Mouse Phenotype (MP)

(show details)
MP termFDR (all)SDMP levelAnnotation (direct or inherited)
Mammalian Phenotype (MP)nervous system phenotype0.000001358Least InformativeDirect
Mammalian Phenotype (MP)mortality/aging0.03749Least InformativeInherited
Mammalian Phenotype (MP)cellular phenotype0.1905Least InformativeInherited
Mammalian Phenotype (MP)lethality during fetal growth through weaning0.01737Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal nervous system development0.07408Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal synaptic transmission0.09168Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal axial skeleton morphology0.09311Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal behavior1Moderately InformativeInherited
Mammalian Phenotype (MP)perinatal lethality0.0002358InformativeDirect
Mammalian Phenotype (MP)abnormal nervous system tract morphology0.04928InformativeInherited
Mammalian Phenotype (MP)abnormal vertebral column morphology0.2314InformativeInherited
Mammalian Phenotype (MP)abnormal glial cell morphology0.3023InformativeInherited
Mammalian Phenotype (MP)abnormal spinal cord morphology0.3938InformativeInherited
Mammalian Phenotype (MP)abnormal CNS synaptic transmission0.5025InformativeInherited
Mammalian Phenotype (MP)abnormal spinal cord ventral commissure morphology0.000001152Highly InformativeDirect
Mammalian Phenotype (MP)abnormal basement membrane morphology0.00001338Highly InformativeDirect
Mammalian Phenotype (MP)abnormal spine curvature0.00002993Highly InformativeDirect
Mammalian Phenotype (MP)decreased excitatory postsynaptic current amplitude0.000092Highly InformativeDirect
Mammalian Phenotype (MP)abnormal GABA-mediated receptor currents0.0007522Highly InformativeDirect
Mammalian Phenotype (MP)abnormal spinal cord white matter morphology0.00141Highly InformativeInherited
Mammalian Phenotype (MP)abnormal glutamate-mediated receptor currents0.01129Highly InformativeInherited
Mammalian Phenotype (MP)abnormal neurotransmitter secretion0.03324Highly InformativeInherited

Document: MP annotation of SCOP domains

Worm Phenotype (WP)

(show details)
WP termFDR (all)SDWP levelAnnotation (direct or inherited)
Worm Phenotype (WP)larval lethal0Least InformativeDirect
Worm Phenotype (WP)larval arrest0Least InformativeDirect
Worm Phenotype (WP)cell development variant0.0023Least InformativeInherited
Worm Phenotype (WP)cell morphology variant0.04269Least InformativeInherited
Worm Phenotype (WP)organ system development variant0.006278Moderately InformativeInherited
Worm Phenotype (WP)cell type morphology variant0.01215Moderately InformativeInherited
Worm Phenotype (WP)neuronal outgrowth variant0.0000005841InformativeDirect
Worm Phenotype (WP)nervous system morphology variant0.009074InformativeInherited
Worm Phenotype (WP)axon guidance variant0.00000003725Highly InformativeDirect
Worm Phenotype (WP)myopodia present0.000001036Highly InformativeDirect
Worm Phenotype (WP)axon morphology variant0.000006167Highly InformativeDirect
Worm Phenotype (WP)muscle system development variant0.0001908Highly InformativeDirect

Document: WP annotation of SCOP domains

Fly Phenotype (FP)

(show details)
FP termFDR (all)SDFP levelAnnotation (direct or inherited)
Fly Phenotype (FP)cell polarity defective0.0000009922InformativeDirect
Fly Phenotype (FP)decreased cell number0.00009262InformativeDirect

Document: FP annotation of SCOP domains

Fly Anatomy (FA)

(show details)
FA termFDR (all)SDFA levelAnnotation (direct or inherited)
Fly Anatomy (FA)somatic cell0Least InformativeDirect
Fly Anatomy (FA)embryo0.02449Least InformativeInherited
Fly Anatomy (FA)anatomical group0.04783Least InformativeInherited
Fly Anatomy (FA)nervous system0.06778Least InformativeInherited
Fly Anatomy (FA)larva0.1299Least InformativeInherited
Fly Anatomy (FA)organ system subdivision0.1787Least InformativeInherited
Fly Anatomy (FA)embryonic/larval nervous system0.01642Moderately InformativeInherited
Fly Anatomy (FA)central nervous system0.02024Moderately InformativeInherited
Fly Anatomy (FA)neuron0.077Moderately InformativeInherited
Fly Anatomy (FA)photoreceptor cell0.002532InformativeInherited
Fly Anatomy (FA)embryonic/larval circulatory system0.02245InformativeInherited
Fly Anatomy (FA)embryonic/larval dorsal vessel0.0008082Highly InformativeDirect

Document: FA annotation of SCOP domains

Zebrafish Anatomy (ZA)

(show details) Document: ZA annotation of SCOP domains

Xenopus Anatomy (XA)

(show details)
XA termFDR (all)SDXA levelAnnotation (direct or inherited)
Xenopus ANatomical entity (XAN)nervous system0.01163Least InformativeInherited
Xenopus ANatomical entity (XAN)urogenital system0.0339Least InformativeInherited
Xenopus ANatomical entity (XAN)cavitated compound organ0.2276Least InformativeInherited
Xenopus ANatomical entity (XAN)trunk0.4803Least InformativeInherited
Xenopus ANatomical entity (XAN)spinal cord0.0003285InformativeDirect

Document: XA annotation of SCOP domains

Jump to [ Top of page · SCOP classification · Human Phenotype (HP) · Mouse Phenotype (MP) · Worm Phenotype (WP) · Fly Phenotype (FP) · Fly Anatomy (FA) · Zebrafish Anatomy (ZA) · Xenopus Anatomy (XA) ]

Internal database links

Superfamily level     Family level

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.

Superfamily level     Family level

Alignments of sequences to 253 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.

Superfamily level

Browse and view proteins in genomes which have different domain combinations including a Concanavalin A-like lectins/glucanases domain.

Superfamily level     Family level

Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.

Jump to [ Top of page · SCOP classification · Human Phenotype (HP) · Mouse Phenotype (MP) · Worm Phenotype (WP) · Fly Phenotype (FP) · Fly Anatomy (FA) · Zebrafish Anatomy (ZA) · Xenopus Anatomy (XA) · Internal database links ]