SUPERFAMILY 1.75 HMM library and genome assignments server

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Single strand DNA-binding domain, SSB family

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   All beta proteins [ 48724] (174)
Fold:   OB-fold [ 50198] (16)
Superfamily:   Nucleic acid-binding proteins [ 50249] (16)
Family:   Single strand DNA-binding domain, SSB [ 50263] (12)


Family statistics
Genomes (1,874) Uniprot 2018_03 genome PDB chains (SCOP 1.75)
Domains 4,597 23,300 59
Proteins 3,506 20,336 40


Disease Ontology (DO)

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show details)
DO termFDR (all)SDDO levelAnnotation (direct or inherited)
Disease Ontology (DO)genetic disease0.0031Moderately InformativeInherited
Disease Ontology (DO)hereditary breast ovarian cancer syndrome0.00006591InformativeDirect

Document: DO annotation of SCOP domains

Human Phenotype (HP)

(show details) Document: HP annotation of SCOP domains

Mouse Phenotype (MP)

(show details)
MP termFDR (all)SDMP levelAnnotation (direct or inherited)
Mammalian Phenotype (MP)cellular phenotype0.009723Least InformativeInherited
Mammalian Phenotype (MP)endocrine/exocrine gland phenotype0.0477Least InformativeInherited
Mammalian Phenotype (MP)abnormal reproductive system morphology0.006076Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal reproductive system physiology0.01442Moderately InformativeInherited
Mammalian Phenotype (MP)neoplasm0.01965Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal cell death0.1762Moderately InformativeInherited
Mammalian Phenotype (MP)abnormal primary sex determination0.0002488InformativeDirect
Mammalian Phenotype (MP)abnormal spermatogenesis0.0002944InformativeDirect
Mammalian Phenotype (MP)abnormal testis morphology0.0004744InformativeDirect
Mammalian Phenotype (MP)increased hemolymphoid system tumor incidence0.0005729InformativeDirect
Mammalian Phenotype (MP)abnormal male reproductive system physiology0.001534InformativeInherited
Mammalian Phenotype (MP)abnormal germ cell morphology0.08567InformativeInherited
Mammalian Phenotype (MP)chromosomal instability0.000000188Highly InformativeDirect
Mammalian Phenotype (MP)decreased male germ cell number0.00005484Highly InformativeDirect
Mammalian Phenotype (MP)small testis0.0001544Highly InformativeDirect
Mammalian Phenotype (MP)abnormal cell nucleus morphology0.01197Highly InformativeInherited

Document: MP annotation of SCOP domains

Worm Phenotype (WP)

(show details)
WP termFDR (all)SDWP levelAnnotation (direct or inherited)
Worm Phenotype (WP)cell development variant0.03081Least InformativeInherited
Worm Phenotype (WP)early embryonic lethal0.0007508Moderately InformativeDirect
Worm Phenotype (WP)germ cell development variant0.0009454Moderately InformativeDirect

Document: WP annotation of SCOP domains

Yeast Phenotype (YP)

(show details)
YP termFDR (all)SDYP levelAnnotation (direct or inherited)
Yeast Phenotype (YP)cell cycle progression0.0005015InformativeDirect

Document: YP annotation of SCOP domains

Fly Phenotype (FP)

(show details)
FP termFDR (all)SDFP levelAnnotation (direct or inherited)
Fly Phenotype (FP)increased mortality0Least InformativeDirect

Document: FP annotation of SCOP domains

Fly Anatomy (FA)

(show details)
FA termFDR (all)SDFA levelAnnotation (direct or inherited)
Fly Anatomy (FA)larva0Least InformativeDirect
Fly Anatomy (FA)nervous system0Least InformativeDirect
Fly Anatomy (FA)organ system subdivision0Least InformativeDirect
Fly Anatomy (FA)central nervous system0Moderately InformativeDirect

Document: FA annotation of SCOP domains

Xenopus Anatomy (XA)

(show details) Document: XA annotation of SCOP domains

Arabidopsis Plant Ontology (AP)

(show details) Document: AP annotation of SCOP domains

UniProtKB KeyWords (KW)

(show details)
KW termFDR (all)SDKW levelAnnotation (direct or inherited)
Post-translational modificationDNA-binding0InformativeDirect

Document: KW annotation of SCOP domains

Jump to [ Top of page · SCOP classification · Disease Ontology (DO) · Human Phenotype (HP) · Mouse Phenotype (MP) · Worm Phenotype (WP) · Yeast Phenotype (YP) · Fly Phenotype (FP) · Fly Anatomy (FA) · Xenopus Anatomy (XA) · Arabidopsis Plant Ontology (AP) · UniProtKB KeyWords (KW) ]

Internal database links

   
Superfamily level     Family level

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


   
Superfamily level     Family level

Alignments of sequences to 186 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Superfamily level

Browse and view proteins in genomes which have different domain combinations including a Nucleic acid-binding proteins domain.


   
Superfamily level     Family level

Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Jump to [ Top of page · SCOP classification · Disease Ontology (DO) · Human Phenotype (HP) · Mouse Phenotype (MP) · Worm Phenotype (WP) · Yeast Phenotype (YP) · Fly Phenotype (FP) · Fly Anatomy (FA) · Xenopus Anatomy (XA) · Arabidopsis Plant Ontology (AP) · UniProtKB KeyWords (KW) · Internal database links ]