SUPERFAMILY 1.75 HMM library and genome assignments server

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EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain family

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   All beta proteins [ 48724] (174)
Fold:   Elongation factor/aminomethyltransferase common domain [ 50464] (2)
Superfamily:   EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain [ 50465]
Family:   EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain [ 50466] (6)


Family statistics
Genomes (3,251) Uniprot 2018_03 genome PDB chains (SCOP 1.75)
Domains 6,392 47,597 24
Proteins 6,383 47,585 24


Enzyme Commission (EC)

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show details)
EC termFDR (all)SDEO levelAnnotation (direct or inherited)
Enzyme Commission (EC)Nucleotidyltransferases0Least InformativeDirect
Enzyme Commission (EC)Phosphotransferases with an alcohol group as accep1Moderately InformativeInherited
Enzyme Commission (EC)Sulfate adenylyltransferase0Highly InformativeDirect
Enzyme Commission (EC)Adenylyl-sulfate kinase0Highly InformativeDirect

Document: EC annotation of SCOP domains

Human Phenotype (HP)

(show details)
HP termFDR (all)SDHP levelAnnotation (direct or inherited)
Phenotypic Abnormality (PA)Abnormality of the eye0Least InformativeDirect
Phenotypic Abnormality (PA)Abnormality of the musculature0Least InformativeDirect
Phenotypic Abnormality (PA)Abnormality of skeletal morphology0Least InformativeDirect
Phenotypic Abnormality (PA)Abnormality of nervous system physiology0Least InformativeDirect
Phenotypic Abnormality (PA)Abnormality of nervous system morphology0Least InformativeDirect
Phenotypic Abnormality (PA)Abnormality of skull size0Moderately InformativeDirect
Phenotypic Abnormality (PA)Aplasia/Hypoplasia involving the central nervous system0Moderately InformativeDirect
Phenotypic Abnormality (PA)Abnormal muscle tone0Moderately InformativeDirect
Phenotypic Abnormality (PA)Abnormality of central motor function0Moderately InformativeDirect
Phenotypic Abnormality (PA)Abnormal eye physiology0Moderately InformativeDirect
Phenotypic Abnormality (PA)Abnormality of forebrain morphology0Moderately InformativeDirect
Phenotypic Abnormality (PA)Microcephaly0InformativeDirect
Phenotypic Abnormality (PA)Hypertonia0InformativeDirect
Phenotypic Abnormality (PA)Spasticity0Highly InformativeDirect

Document: HP annotation of SCOP domains

Worm Phenotype (WP)

(show details)
WP termFDR (all)SDWP levelAnnotation (direct or inherited)
Worm Phenotype (WP)cell physiology variant0.008946Least InformativeInherited
Worm Phenotype (WP)blast cell physiology variant0.008946Least InformativeInherited
Worm Phenotype (WP)organism metabolism processing variant0.02014Least InformativeInherited
Worm Phenotype (WP)cell morphology variant0.06209Least InformativeInherited
Worm Phenotype (WP)cell development variant0.2373Least InformativeInherited
Worm Phenotype (WP)cell homeostasis metabolism variant0.0000434Moderately InformativeDirect
Worm Phenotype (WP)protein protein interaction variant0.0002712Moderately InformativeDirect
Worm Phenotype (WP)germ cell differentiation variant0.006966Moderately InformativeInherited
Worm Phenotype (WP)early embryonic lethal0.0335Moderately InformativeInherited
Worm Phenotype (WP)germ cell development variant0.03737Moderately InformativeInherited
Worm Phenotype (WP)reproductive system morphology variant0.0439Moderately InformativeInherited
Worm Phenotype (WP)pattern of transgene expression variant0.1361Moderately InformativeInherited
Worm Phenotype (WP)cell division variant0.2831Moderately InformativeInherited
Worm Phenotype (WP)cell type morphology variant0.4919Moderately InformativeInherited
Worm Phenotype (WP)pachytene progression during oogenesis variant0.0001639InformativeDirect
Worm Phenotype (WP)diplotene progression during oogenesis variant0.0001639InformativeDirect
Worm Phenotype (WP)germ cell compartment expansion variant0.000541InformativeDirect
Worm Phenotype (WP)rachis morphology variant0.0005714InformativeDirect
Worm Phenotype (WP)oocyte morphology variant0.002428InformativeInherited
Worm Phenotype (WP)gonad vesiculated0.00004757Highly InformativeDirect
Worm Phenotype (WP)rachis narrow0.0001236Highly InformativeDirect
Worm Phenotype (WP)oocyte number decreased0.0001608Highly InformativeDirect

Document: WP annotation of SCOP domains

Fly Anatomy (FA)

(show details) Document: FA annotation of SCOP domains

Zebrafish Anatomy (ZA)

(show details)
ZA termFDR (all)SDZA levelAnnotation (direct or inherited)
Zebrafish Anatomy (ZA)organism subdivision0Least InformativeDirect
Zebrafish Anatomy (ZA)cavitated compound organ0Least InformativeDirect

Document: ZA annotation of SCOP domains

Xenopus Anatomy (XA)

(show details)
XA termFDR (all)SDXA levelAnnotation (direct or inherited)
Xenopus ANatomical entity (XAN)embryo0Least InformativeDirect
Xenopus ANatomical entity (XAN)urogenital system0Least InformativeDirect
Xenopus ANatomical entity (XAN)nervous system0Least InformativeDirect
Xenopus ANatomical entity (XAN)head0Least InformativeDirect
Xenopus ANatomical entity (XAN)trunk0Least InformativeDirect
Xenopus ANatomical entity (XAN)cavitated compound organ0Least InformativeDirect
Xenopus ANatomical entity (XAN)brain0Moderately InformativeDirect
Xenopus ANatomical entity (XAN)testis0Moderately InformativeDirect
Xenopus ANatomical entity (XAN)germ cell0.6435Moderately InformativeInherited
Xenopus DEvelopment stage (XDE)post-embryonic stage0Least InformativeDirect

Document: XA annotation of SCOP domains

Arabidopsis Plant Ontology (AP)

(show details) Document: AP annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEC levelAnnotation (direct or inherited)
Enzyme Commission (EC)Transferases0Least InformativeDirect
Enzyme Commission (EC)Nucleotidyltransferases0Moderately InformativeDirect
Enzyme Commission (EC)Phosphotransferases with an alcohol group as acceptor1Moderately InformativeInherited

Document: EC annotation of SCOP domains

Jump to [ Top of page · SCOP classification · Enzyme Commission (EC) · Human Phenotype (HP) · Worm Phenotype (WP) · Fly Anatomy (FA) · Zebrafish Anatomy (ZA) · Xenopus Anatomy (XA) · Arabidopsis Plant Ontology (AP) · Enzyme Commission (EC) ]

Internal database links

   
Superfamily level     Family level

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


   
Superfamily level     Family level

Alignments of sequences to 15 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Superfamily level

Browse and view proteins in genomes which have different domain combinations including a EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain domain.


   
Superfamily level     Family level

Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Jump to [ Top of page · SCOP classification · Enzyme Commission (EC) · Human Phenotype (HP) · Worm Phenotype (WP) · Fly Anatomy (FA) · Zebrafish Anatomy (ZA) · Xenopus Anatomy (XA) · Arabidopsis Plant Ontology (AP) · Enzyme Commission (EC) · Internal database links ]