SUPERFAMILY 1.75 HMM library and genome assignments server

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Third domain of FERM family

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   All beta proteins [ 48724] (174)
Fold:   PH domain-like barrel [ 50728] (2)
Superfamily:   PH domain-like [ 50729] (13)
Family:   Third domain of FERM [ 50776] (8)


Family statistics
Genomes (152) Uniprot 2018_03 genome PDB chains (SCOP 1.75)
Domains 1,619 5,703 22
Proteins 1,618 5,697 22


Enzyme Commission (EC)

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show details)
EC termFDR (all)SDEO levelAnnotation (direct or inherited)
Enzyme Commission (EC)Acting on ester bonds0.000000000007268Least InformativeDirect
Enzyme Commission (EC)Phosphoric monoester hydrolases0Moderately InformativeDirect
Enzyme Commission (EC)Protein-tyrosine-phosphatase0InformativeDirect
Enzyme Commission (EC)Non-specific protein-tyrosine kinase0Highly InformativeDirect

Document: EC annotation of SCOP domains

Disease Ontology (DO)

(show details)
DO termFDR (all)SDDO levelAnnotation (direct or inherited)
Disease Ontology (DO)organ system cancer0.9908Least InformativeInherited
Disease Ontology (DO)nervous system cancer0.04996Moderately InformativeInherited
Disease Ontology (DO)meningioma0.0005504InformativeDirect

Document: DO annotation of SCOP domains

Worm Phenotype (WP)

(show details)
WP termFDR (all)SDWP levelAnnotation (direct or inherited)
Worm Phenotype (WP)cell morphology variant0.02534Least InformativeInherited
Worm Phenotype (WP)cell development variant0.1196Least InformativeInherited
Worm Phenotype (WP)cell physiology variant0.232Least InformativeInherited
Worm Phenotype (WP)blast cell physiology variant0.232Least InformativeInherited
Worm Phenotype (WP)organism behavior variant0.3047Least InformativeInherited
Worm Phenotype (WP)organism metabolism processing variant0.6489Least InformativeInherited
Worm Phenotype (WP)protein expression variant0.003717Moderately InformativeInherited
Worm Phenotype (WP)cell type morphology variant0.006807Moderately InformativeInherited
Worm Phenotype (WP)movement variant0.01855Moderately InformativeInherited
Worm Phenotype (WP)locomotion variant0.1075Moderately InformativeInherited
Worm Phenotype (WP)muscle cell physiology variant0.000003298InformativeDirect
Worm Phenotype (WP)mitochondria morphology variant0.00004405InformativeDirect
Worm Phenotype (WP)body wall muscle sarcomere morphology variant0.00007056InformativeDirect
Worm Phenotype (WP)level of protein expression variant0.00008384InformativeDirect
Worm Phenotype (WP)cell component localization variant0.0003974InformativeDirect
Worm Phenotype (WP)muscle cell attachment variant0.0000007061Highly InformativeDirect
Worm Phenotype (WP)protein expression reduced0.00002597Highly InformativeDirect

Document: WP annotation of SCOP domains

Fly Anatomy (FA)

(show details)
FA termFDR (all)SDFA levelAnnotation (direct or inherited)
Fly Anatomy (FA)tagma0Least InformativeDirect
Fly Anatomy (FA)adult0Least InformativeDirect
Fly Anatomy (FA)nervous system0Least InformativeDirect
Fly Anatomy (FA)anatomical group0Least InformativeDirect
Fly Anatomy (FA)organ system subdivision0Least InformativeDirect
Fly Anatomy (FA)adult head0.0006917Moderately InformativeDirect
Fly Anatomy (FA)multi-cell-component structure0.00143Moderately InformativeInherited
Fly Anatomy (FA)peripheral nervous system0.01035Moderately InformativeInherited
Fly Anatomy (FA)nerve0.1079InformativeInherited
Fly Anatomy (FA)embryonic/larval optic stalk0.00001013Highly InformativeDirect

Document: FA annotation of SCOP domains

Zebrafish Anatomy (ZA)

(show details) Document: ZA annotation of SCOP domains

Xenopus Anatomy (XA)

(show details)
XA termFDR (all)SDXA levelAnnotation (direct or inherited)
Xenopus ANatomical entity (XAN)nervous system0.002032Least InformativeInherited

Document: XA annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEC levelAnnotation (direct or inherited)
Enzyme Commission (EC)Hydrolases0.0005106Least InformativeDirect
Enzyme Commission (EC)Transferases0.03182Least InformativeInherited
Enzyme Commission (EC)Acting on ester bonds0.0000000003832Moderately InformativeDirect
Enzyme Commission (EC)Acyltransferases0.00384Moderately InformativeInherited
Enzyme Commission (EC)Phosphoric monoester hydrolases0InformativeDirect
Enzyme Commission (EC)Aminoacyltransferases0.0000002185InformativeDirect
Enzyme Commission (EC)Non-specific protein-tyrosine kinase0Highly InformativeDirect
Enzyme Commission (EC)Protein-tyrosine-phosphatase0Highly InformativeDirect

Document: EC annotation of SCOP domains

Jump to [ Top of page · SCOP classification · Enzyme Commission (EC) · Disease Ontology (DO) · Worm Phenotype (WP) · Fly Anatomy (FA) · Zebrafish Anatomy (ZA) · Xenopus Anatomy (XA) · Enzyme Commission (EC) ]

Internal database links

   
Superfamily level     Family level

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


   
Superfamily level     Family level

Alignments of sequences to 129 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Superfamily level

Browse and view proteins in genomes which have different domain combinations including a PH domain-like domain.


   
Superfamily level     Family level

Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Jump to [ Top of page · SCOP classification · Enzyme Commission (EC) · Disease Ontology (DO) · Worm Phenotype (WP) · Fly Anatomy (FA) · Zebrafish Anatomy (ZA) · Xenopus Anatomy (XA) · Enzyme Commission (EC) · Internal database links ]