SUPERFAMILY 1.75 HMM library and genome assignments server

Superfamily is undergoing a server migration - you are now browsing on the new server. Please contact us if you experience any problems.


Hedgehog C-terminal (Hog) autoprocessing domain family

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   All beta proteins [ 48724] (174)
Fold:   Hedgehog/intein (Hint) domain [ 51293]
Superfamily:   Hedgehog/intein (Hint) domain [ 51294] (2)
Family:   Hedgehog C-terminal (Hog) autoprocessing domain [ 51295]


Family statistics
Genomes (22) Uniprot 2018_03 genome PDB chains (SCOP 1.75)
Domains 24 70 1
Proteins 24 70 1


Human Phenotype (HP)

(
show details)
HP termFDR (all)SDHP levelAnnotation (direct or inherited)
Phenotypic Abnormality (PA)Abnormality of limbs0Least InformativeDirect
Phenotypic Abnormality (PA)Abnormality of the lower limb0Moderately InformativeDirect

Document: HP annotation of SCOP domains

Mouse Phenotype (MP)

(show details)
MP termFDR (all)SDMP levelAnnotation (direct or inherited)
Mammalian Phenotype (MP)nervous system phenotype0Least InformativeDirect
Mammalian Phenotype (MP)endocrine/exocrine gland phenotype0Least InformativeDirect
Mammalian Phenotype (MP)cellular phenotype0Least InformativeDirect
Mammalian Phenotype (MP)abnormal digestive system morphology0Moderately InformativeDirect

Document: MP annotation of SCOP domains

Worm Phenotype (WP)

(show details)
WP termFDR (all)SDWP levelAnnotation (direct or inherited)
Worm Phenotype (WP)larval arrest0Least InformativeDirect
Worm Phenotype (WP)larval lethal0Least InformativeDirect
Worm Phenotype (WP)slow growth0Least InformativeDirect
Worm Phenotype (WP)organism behavior variant0.004481Least InformativeInherited
Worm Phenotype (WP)cell physiology variant0.01888Least InformativeInherited
Worm Phenotype (WP)pericellular component development variant0.00000007479Moderately InformativeDirect
Worm Phenotype (WP)organism segment morphology variant0.000000514Moderately InformativeDirect
Worm Phenotype (WP)body region morphology variant0.000000529Moderately InformativeDirect
Worm Phenotype (WP)movement variant0.0001567Moderately InformativeDirect
Worm Phenotype (WP)small0.00000000006234InformativeDirect
Worm Phenotype (WP)molt variant0Highly InformativeDirect
Worm Phenotype (WP)cuticle morphology variant0.0000000000009842Highly InformativeDirect
Worm Phenotype (WP)pericellular component physiology variant0.0000000000102Highly InformativeDirect
Worm Phenotype (WP)body region development variant0.00000000002984Highly InformativeDirect
Worm Phenotype (WP)epithelial system physiology variant0.000000001672Highly InformativeDirect
Worm Phenotype (WP)cell secretion variant0.000000003225Highly InformativeDirect
Worm Phenotype (WP)alimentary system morphology variant0.0000007282Highly InformativeDirect

Document: WP annotation of SCOP domains

Zebrafish Anatomy (ZA)

(show details) Document: ZA annotation of SCOP domains

Jump to [ Top of page · SCOP classification · Human Phenotype (HP) · Mouse Phenotype (MP) · Worm Phenotype (WP) · Zebrafish Anatomy (ZA) ]

Internal database links

   
Superfamily level     Family level

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


   
Superfamily level     Family level

Alignments of sequences to 7 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Superfamily level

Browse and view proteins in genomes which have different domain combinations including a Hedgehog/intein (Hint) domain domain.


   
Superfamily level     Family level

Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Jump to [ Top of page · SCOP classification · Human Phenotype (HP) · Mouse Phenotype (MP) · Worm Phenotype (WP) · Zebrafish Anatomy (ZA) · Internal database links ]