SUPERFAMILY 1.75 HMM library and genome assignments server

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Group II chaperonin (CCT, TRIC), apical domain family

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   Alpha and beta proteins (a/b) [ 51349] (147)
Fold:   The "swivelling" beta/beta/alpha domain [ 52008] (10)
Superfamily:   GroEL apical domain-like [ 52029] (2)
Family:   Group II chaperonin (CCT, TRIC), apical domain [ 52034]


Family statistics
Genomes (656) Uniprot 2018_03 genome PDB chains (SCOP 1.75)
Domains 1,031 4,204 8
Proteins 1,031 4,202 8


Enzyme Commission (EC)

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show details)
EC termFDR (all)SDEO levelAnnotation (direct or inherited)
Enzyme Commission (EC)Phosphotransferases with an alcohol group as accep0Moderately InformativeDirect

Document: EC annotation of SCOP domains

Human Phenotype (HP)

(show details)
HP termFDR (all)SDHP levelAnnotation (direct or inherited)
Phenotypic Abnormality (PA)Abnormality of nervous system physiology0Least InformativeDirect

Document: HP annotation of SCOP domains

Mouse Phenotype (MP)

(show details)
MP termFDR (all)SDMP levelAnnotation (direct or inherited)
Mammalian Phenotype (MP)mortality/aging0Least InformativeDirect
Mammalian Phenotype (MP)prenatal lethality0Moderately InformativeDirect

Document: MP annotation of SCOP domains

Worm Phenotype (WP)

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WP termFDR (all)SDWP levelAnnotation (direct or inherited)
Worm Phenotype (WP)organism metabolism processing variant0Least InformativeDirect
Worm Phenotype (WP)larval arrest0Least InformativeDirect
Worm Phenotype (WP)cell development variant0.000008235Least InformativeDirect
Worm Phenotype (WP)cell physiology variant0.00004463Least InformativeDirect
Worm Phenotype (WP)organism behavior variant0.001314Least InformativeInherited
Worm Phenotype (WP)organism environmental stimulus response variant0.001564Least InformativeInherited
Worm Phenotype (WP)germ cell differentiation variant0.0000000003349Moderately InformativeDirect
Worm Phenotype (WP)early embryonic lethal0.0000000008215Moderately InformativeDirect
Worm Phenotype (WP)cell organization biogenesis variant0.000000001049Moderately InformativeDirect
Worm Phenotype (WP)germ cell development variant0.00000001583Moderately InformativeDirect
Worm Phenotype (WP)reproductive system morphology variant0.00000004955Moderately InformativeDirect
Worm Phenotype (WP)level of transgene expression variant0.0000004493Moderately InformativeDirect
Worm Phenotype (WP)pattern of transgene expression variant0.000004652Moderately InformativeDirect
Worm Phenotype (WP)cell cycle variant0.00006551Moderately InformativeDirect
Worm Phenotype (WP)cell death variant0.0002713Moderately InformativeDirect
Worm Phenotype (WP)cell division variant0.001067Moderately InformativeInherited
Worm Phenotype (WP)organ system development variant0.0134Moderately InformativeInherited
Worm Phenotype (WP)organism stress response variant0.04798Moderately InformativeInherited
Worm Phenotype (WP)cell type morphology variant0.144Moderately InformativeInherited
Worm Phenotype (WP)cell homeostasis metabolism variant0.3802Moderately InformativeInherited
Worm Phenotype (WP)chemical response variant0.4659Moderately InformativeInherited
Worm Phenotype (WP)protein protein interaction variant0.9893Moderately InformativeInherited
Worm Phenotype (WP)pachytene progression during oogenesis variant0.00000000000982InformativeDirect
Worm Phenotype (WP)germ cell compartment expansion variant0.0000000001243InformativeDirect
Worm Phenotype (WP)oocyte morphology variant0.000000003301InformativeDirect
Worm Phenotype (WP)transgene expression increased0.000000003636InformativeDirect
Worm Phenotype (WP)endocytic transport defect0.00000004208InformativeDirect
Worm Phenotype (WP)accumulated germline cell corpses0.0000002908InformativeDirect
Worm Phenotype (WP)vesicle organization variant0.000000355InformativeDirect
Worm Phenotype (WP)hermaphrodite physiology variant0.000000399InformativeDirect
Worm Phenotype (WP)avoids bacterial lawn0.00000123InformativeDirect
Worm Phenotype (WP)germ cell physiology variant0.000001314InformativeDirect
Worm Phenotype (WP)vulva morphology variant0.00000374InformativeDirect
Worm Phenotype (WP)nuclear positioning variant0.000008964InformativeDirect
Worm Phenotype (WP)protein metabolism variant0.0002449InformativeDirect
Worm Phenotype (WP)sick0.0003722InformativeDirect
Worm Phenotype (WP)gonad development variant0.001153InformativeInherited
Worm Phenotype (WP)cell stress response variant0.001208InformativeInherited
Worm Phenotype (WP)organism temperature response variant0.002944InformativeInherited
Worm Phenotype (WP)cell component localization variant0.003262InformativeInherited
Worm Phenotype (WP)life span variant0.005931InformativeInherited
Worm Phenotype (WP)rachis morphology variant0.09307InformativeInherited
Worm Phenotype (WP)mitosis variant0.1112InformativeInherited
Worm Phenotype (WP)organism pathogen response variant0.287InformativeInherited
Worm Phenotype (WP)meiotic chromosome organization variant0.6993InformativeInherited
Worm Phenotype (WP)oocytes small0.00000000000001374Highly InformativeDirect
Worm Phenotype (WP)pleiotropic defects severe early emb0.000000000005098Highly InformativeDirect
Worm Phenotype (WP)germline nuclear positioning variant0.0000000003367Highly InformativeDirect
Worm Phenotype (WP)rachis narrow0.0000000007949Highly InformativeDirect
Worm Phenotype (WP)RAB-11 recycling endosome localization variant0.00000001961Highly InformativeDirect
Worm Phenotype (WP)unfolded protein response variant0.00000004692Highly InformativeDirect
Worm Phenotype (WP)germ cell compartment anucleate0.00000007772Highly InformativeDirect
Worm Phenotype (WP)organism heat response variant0.0000001685Highly InformativeDirect
Worm Phenotype (WP)organism pigmentation variant0.0000006473Highly InformativeDirect
Worm Phenotype (WP)extended life span0.00001435Highly InformativeDirect
Worm Phenotype (WP)male somatic gonad development variant0.00002728Highly InformativeDirect
Worm Phenotype (WP)gonad arm morphology variant0.000049Highly InformativeDirect
Worm Phenotype (WP)chromosome condensation variant0.00005899Highly InformativeDirect
Worm Phenotype (WP)no induction of antimicrobial peptide expression after infection0.0001267Highly InformativeDirect
Worm Phenotype (WP)no oocytes0.0001952Highly InformativeDirect
Worm Phenotype (WP)cell membrane organization biogenesis variant0.0002525Highly InformativeDirect
Worm Phenotype (WP)diakinesis progression during oogenesis variant0.1559Highly InformativeInherited

Document: WP annotation of SCOP domains

Yeast Phenotype (YP)

(show details)
YP termFDR (all)SDYP levelAnnotation (direct or inherited)
Yeast Phenotype (YP)chromosome/plasmid maintenance0.0006238InformativeDirect

Document: YP annotation of SCOP domains

Fly Phenotype (FP)

(show details)
FP termFDR (all)SDFP levelAnnotation (direct or inherited)
Fly Phenotype (FP)visible0Moderately InformativeDirect

Document: FP annotation of SCOP domains

Fly Anatomy (FA)

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FA termFDR (all)SDFA levelAnnotation (direct or inherited)
Fly Anatomy (FA)tagma0Least InformativeDirect
Fly Anatomy (FA)adult0Least InformativeDirect
Fly Anatomy (FA)multi-tissue structure0.1656Least InformativeInherited
Fly Anatomy (FA)adult head0Moderately InformativeDirect
Fly Anatomy (FA)circulatory system0.000001335Moderately InformativeDirect
Fly Anatomy (FA)adult heart0.0000000001626InformativeDirect

Document: FA annotation of SCOP domains

Zebrafish Anatomy (ZA)

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ZA termFDR (all)SDZA levelAnnotation (direct or inherited)
Zebrafish Anatomy (ZA)cell0.2784Least InformativeInherited
Zebrafish Anatomy (ZA)electrically active cell0.0105Moderately InformativeInherited
Zebrafish Anatomy (ZA)portion of tissue0.04918Moderately InformativeInherited
Zebrafish Anatomy (ZA)skeletal muscle0.00000226InformativeDirect
Zebrafish Anatomy (ZA)muscle cell0.00002547InformativeDirect
Zebrafish Anatomy (ZA)myotome0.0000002585Highly InformativeDirect
Zebrafish Anatomy (ZA)solid compound organ0.0009898Highly InformativeDirect

Document: ZA annotation of SCOP domains

Xenopus Anatomy (XA)

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XA termFDR (all)SDXA levelAnnotation (direct or inherited)
Xenopus ANatomical entity (XAN)nervous system0Least InformativeDirect
Xenopus ANatomical entity (XAN)head0Least InformativeDirect
Xenopus ANatomical entity (XAN)cavitated compound organ0Least InformativeDirect
Xenopus ANatomical entity (XAN)embryo0.05246Least InformativeInherited
Xenopus ANatomical entity (XAN)tissue0.2059Least InformativeInherited
Xenopus ANatomical entity (XAN)brain0Moderately InformativeDirect
Xenopus ANatomical entity (XAN)tail region0.0004866Moderately InformativeDirect
Xenopus ANatomical entity (XAN)musculoskeletal system0.001583Moderately InformativeInherited
Xenopus ANatomical entity (XAN)embryonic structure0.01038Moderately InformativeInherited
Xenopus ANatomical entity (XAN)muscle0.00001227InformativeDirect
Xenopus ANatomical entity (XAN)endocrine system0.00006095InformativeDirect
Xenopus ANatomical entity (XAN)tail0.0002369InformativeDirect
Xenopus ANatomical entity (XAN)mesoderm0.06354InformativeInherited
Xenopus ANatomical entity (XAN)thymus0.00004282Highly InformativeDirect
Xenopus ANatomical entity (XAN)lateral plate mesoderm0.003613Highly InformativeInherited
Xenopus DEvelopment stage (XDE)post-embryonic stage0.143Least InformativeInherited
Xenopus DEvelopment stage (XDE)NF stage 660.0009945InformativeDirect

Document: XA annotation of SCOP domains

Arabidopsis Plant Ontology (AP)

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AP termFDR (all)SDAP levelAnnotation (direct or inherited)
Plant ANatomical entity (PAN)shoot apex0Least InformativeDirect
Plant ANatomical entity (PAN)shoot internode0Least InformativeDirect
Plant ANatomical entity (PAN)root0Least InformativeDirect
Plant ANatomical entity (PAN)plant embryo0Least InformativeDirect
Plant ANatomical entity (PAN)seed0Least InformativeDirect
Plant ANatomical entity (PAN)portion of meristem tissue0Least InformativeDirect
Plant ANatomical entity (PAN)vascular leaf0Least InformativeDirect
Plant ANatomical entity (PAN)megasporophyll0Least InformativeDirect
Plant ANatomical entity (PAN)microsporophyll0Least InformativeDirect
Plant ANatomical entity (PAN)sepal0Least InformativeDirect
Plant ANatomical entity (PAN)petal0Least InformativeDirect
Plant ANatomical entity (PAN)stem0Least InformativeDirect
Plant ANatomical entity (PAN)inflorescence0Least InformativeDirect
Plant ANatomical entity (PAN)androecium0Least InformativeDirect
Plant ANatomical entity (PAN)gynoecium0Least InformativeDirect
Plant ANatomical entity (PAN)leaf lamina0Least InformativeDirect
Plant ANatomical entity (PAN)collective leaf structure0Least InformativeDirect
Plant ANatomical entity (PAN)branch0Least InformativeDirect
Plant ANatomical entity (PAN)sporangium0Least InformativeDirect
Plant ANatomical entity (PAN)phyllome apex0Least InformativeDirect
Plant ANatomical entity (PAN)microgametophyte0Least InformativeDirect
Plant structure DEvelopment stage (PDE)4 leaf senescence stage0Least InformativeDirect
Plant structure DEvelopment stage (PDE)E expanded cotyledon stage0Least InformativeDirect
Plant structure DEvelopment stage (PDE)F mature embryo stage0Least InformativeDirect
Plant structure DEvelopment stage (PDE)C globular stage0Least InformativeDirect
Plant structure DEvelopment stage (PDE)D bilateral stage0Least InformativeDirect
Plant structure DEvelopment stage (PDE)LP.08 eight leaves visible stage0Least InformativeDirect
Plant structure DEvelopment stage (PDE)LP.10 ten leaves visible stage0Least InformativeDirect
Plant structure DEvelopment stage (PDE)LP.04 four leaves visible stage0Least InformativeDirect
Plant structure DEvelopment stage (PDE)LP.06 six leaves visible stage0Least InformativeDirect
Plant structure DEvelopment stage (PDE)seed development stage0.0001592InformativeDirect

Document: AP annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEC levelAnnotation (direct or inherited)
Enzyme Commission (EC)Transferases0Least InformativeDirect
Enzyme Commission (EC)Phosphotransferases with an alcohol group as acceptor0Moderately InformativeDirect

Document: EC annotation of SCOP domains

Jump to [ Top of page · SCOP classification · Enzyme Commission (EC) · Human Phenotype (HP) · Mouse Phenotype (MP) · Worm Phenotype (WP) · Yeast Phenotype (YP) · Fly Phenotype (FP) · Fly Anatomy (FA) · Zebrafish Anatomy (ZA) · Xenopus Anatomy (XA) · Arabidopsis Plant Ontology (AP) · Enzyme Commission (EC) ]

Internal database links

   
Superfamily level     Family level

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


   
Superfamily level     Family level

Alignments of sequences to 11 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Superfamily level

Browse and view proteins in genomes which have different domain combinations including a GroEL apical domain-like domain.


   
Superfamily level     Family level

Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Jump to [ Top of page · SCOP classification · Enzyme Commission (EC) · Human Phenotype (HP) · Mouse Phenotype (MP) · Worm Phenotype (WP) · Yeast Phenotype (YP) · Fly Phenotype (FP) · Fly Anatomy (FA) · Zebrafish Anatomy (ZA) · Xenopus Anatomy (XA) · Arabidopsis Plant Ontology (AP) · Enzyme Commission (EC) · Internal database links ]