SUPERFAMILY 1.73 HMM library and genome assignments server


Class I glutamine amidotransferase-like superfamily

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   Alpha and beta proteins (a/b) [ 51349] (141)
  Mainly parallel beta sheets (beta-alpha-beta units)
Fold:   Flavodoxin-like [ 52171] (15)
  3 layers, a/b/a; parallel beta-sheet of 5 strand, order 21345
Superfamily:   Class I glutamine amidotransferase-like [ 52317] (8)
Families:   Class I glutamine amidotransferases (GAT) [ 52318] (11)
  contains a catalytic Cys-His-Glu triad
  A4 beta-galactosidase middle domain [ 82351]
  probable non-catalytic branch of the class I GAT family; overall fold is very similar but the active site is not conserved
  DJ-1/PfpI [ 52325] (9)
  contains a catalytic triad or dyad different from the class I GAT triad
  Catalase, C-terminal domain [ 52328]
  Aspartyl dipeptidase PepE [ 52331]
  probable circular permutation in the common core; contains a catalytic Ser-His-Glu triad
  ThuA-like [ 110486]
  Pfam 06283; overall fold is very similar the class I GAT family but the putative active site has a different structure
  LD-carboxypeptidase A N-terminal domain-like [ 142074]
  N-terminal half of Pfam 02016
  HTS-like [ 142077]
  Pfam 04204


Superfamily statistics
Genomes (1,234) UniProt 15.0 PDB chains (SCOP 1.73)
Domains 17,921 21,731 66
Proteins 17,818 21,649 66


Functional annotation
General category Metabolism
Detailed category Transferases

Function annotation of SCOP domain superfamilies

Jump to [ Top of page · SCOP classification · Functional annotation ]

Internal database links

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


Alignments of sequences to 34 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Browse and view proteins in genomes which have different domain combinations including a Class I glutamine amidotransferase-like domain.


Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Explore domain occurrence network where nodes represent genomes and edges are domain architectures (shared between genomes) containing the superfamily of interest.

There are 34 hidden Markov models representing the Class I glutamine amidotransferase-like superfamily. Information on how the models are built, and plots showing hydrophobicity, match emmission probabilities and insertion/deletion probabilities can be inspected.


Jump to [ Top of page · SCOP classification · Functional annotation · Internal database links ]