SUPERFAMILY 1.73 HMM library and genome assignments server


Adenine nucleotide alpha hydrolases-like superfamily

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   Alpha and beta proteins (a/b) [ 51349] (141)
  Mainly parallel beta sheets (beta-alpha-beta units)
Fold:   Adenine nucleotide alpha hydrolase-like [ 52373] (3)
  core: 3 layers, a/b/a ; parallel beta-sheet of 5 strands, order 32145
Superfamily:   Adenine nucleotide alpha hydrolases-like [ 52402] (6)
Families:   N-type ATP pyrophosphatases [ 52403] (7)
  PP-loop ATPase [ 82359] (2)
  PAPS reductase-like [ 52410] (2)
  ETFP subunits [ 52432] (2)
  alpha/beta heterodimer of homologous subunits; contains additional strands on both edges of the core sheet
  Universal stress protein-like [ 52436] (6)
  Pfam 00582
  ThiI-like [ 142093] (2)
  Pfam 02568


Superfamily statistics
Genomes (1,234) UniProt 15.0 PDB chains (SCOP 1.73)
Domains 21,094 23,775 32
Proteins 20,201 22,684 32


Functional annotation
General category Metabolism
Detailed category Nucleotide metabolism and transport

Function annotation of SCOP domain superfamilies

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Internal database links

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


Alignments of sequences to 30 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Browse and view proteins in genomes which have different domain combinations including a Adenine nucleotide alpha hydrolases-like domain.


Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Explore domain occurrence network where nodes represent genomes and edges are domain architectures (shared between genomes) containing the superfamily of interest.

There are 30 hidden Markov models representing the Adenine nucleotide alpha hydrolases-like superfamily. Information on how the models are built, and plots showing hydrophobicity, match emmission probabilities and insertion/deletion probabilities can be inspected.


Jump to [ Top of page · SCOP classification · Functional annotation · Internal database links ]