SUPERFAMILY 1.75 HMM library and genome assignments server

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BC N-terminal domain-like family

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   Alpha and beta proteins (a/b) [ 51349] (147)
Fold:   PreATP-grasp domain [ 52439]
Superfamily:   PreATP-grasp domain [ 52440] (8)
Family:   BC N-terminal domain-like [ 52441] (6)


Family statistics
Genomes (3,101) Uniprot 2018_03 genome PDB chains (SCOP 1.75)
Domains 16,916 131,762 19
Proteins 13,688 107,951 16


Enzyme Commission (EC)

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show details)
EC termFDR (all)SDEO levelAnnotation (direct or inherited)
Enzyme Commission (EC)Ligases0Least InformativeDirect
Enzyme Commission (EC)Lyases1Least InformativeInherited
Enzyme Commission (EC)Transferring one-carbon groups1Least InformativeInherited
Enzyme Commission (EC)Forming carbon-nitrogen bonds0Moderately InformativeDirect
Enzyme Commission (EC)Carboxy-lyases0.5299Moderately InformativeInherited
Enzyme Commission (EC)Acting on carbon-nitrogen bonds, other than peptid1Moderately InformativeInherited
Enzyme Commission (EC)Carbon--nitrogen ligases with glutamine as amido-N0InformativeDirect
Enzyme Commission (EC)Other carbon--nitrogen ligases0.0000008974InformativeDirect
Enzyme Commission (EC)In cyclic amides0.02203InformativeInherited
Enzyme Commission (EC)Hydroxymethyl-, formyl- and related transferases0.4651InformativeInherited
Enzyme Commission (EC)Carbamoyl-phosphate synthase (glutamine-hydrolyzin0Highly InformativeDirect
Enzyme Commission (EC)Phosphoribosylamine--glycine ligase0Highly InformativeDirect
Enzyme Commission (EC)Phosphoribosylaminoimidazole carboxylase0Highly InformativeDirect
Enzyme Commission (EC)Biotin carboxylase0Highly InformativeDirect
Enzyme Commission (EC)Pyruvate carboxylase0.000000000000002579Highly InformativeDirect
Enzyme Commission (EC)Phosphoribosylglycinamide formyltransferase0.000000000000006154Highly InformativeDirect
Enzyme Commission (EC)Phosphoribosylformylglycinamidine cyclo-ligase0.00000000411Highly InformativeDirect
Enzyme Commission (EC)Methylcrotonoyl-CoA carboxylase0.00001139Highly InformativeDirect
Enzyme Commission (EC)Dihydroorotase0.0003129Highly InformativeDirect
Enzyme Commission (EC)Carboxyl- and carbamoyltransferases0.002062Highly InformativeInherited

Document: EC annotation of SCOP domains

Disease Ontology (DO)

(show details)
DO termFDR (all)SDDO levelAnnotation (direct or inherited)
Disease Ontology (DO)disease of metabolism0.001386Moderately InformativeInherited
Disease Ontology (DO)glucose metabolism disease1InformativeInherited

Document: DO annotation of SCOP domains

Human Phenotype (HP)

(show details)
HP termFDR (all)SDHP levelAnnotation (direct or inherited)
Phenotypic Abnormality (PA)Abnormality of the musculature0Least InformativeDirect
Phenotypic Abnormality (PA)Abnormality of metabolism/homeostasis0.04788Least InformativeInherited
Phenotypic Abnormality (PA)Abnormality of the genitourinary system0.04961Least InformativeInherited
Phenotypic Abnormality (PA)Abnormality of nervous system physiology0.2092Least InformativeInherited
Phenotypic Abnormality (PA)Abnormality of the digestive system0.2695Least InformativeInherited
Phenotypic Abnormality (PA)Abnormal muscle tone0Moderately InformativeDirect
Phenotypic Abnormality (PA)Abnormality of the urinary system physiology0.0008848Moderately InformativeDirect
Phenotypic Abnormality (PA)Abnormal circulating metabolite concentration0.001531Moderately InformativeInherited
Phenotypic Abnormality (PA)Abnormal homeostasis0.005369Moderately InformativeInherited
Phenotypic Abnormality (PA)Abnormality of higher mental function0.0514Moderately InformativeInherited
Phenotypic Abnormality (PA)Behavioral abnormality0.07379Moderately InformativeInherited
Phenotypic Abnormality (PA)Abnormality of digestive system physiology0.412Moderately InformativeInherited
Phenotypic Abnormality (PA)Azotemia0.000001253InformativeDirect
Phenotypic Abnormality (PA)Aciduria0.0006932InformativeDirect
Phenotypic Abnormality (PA)Abnormal circulating carboxylic acid concentration0.0008559InformativeDirect
Phenotypic Abnormality (PA)Nausea and vomiting0.007107InformativeInherited
Phenotypic Abnormality (PA)Reduced consciousness/confusion0.01151InformativeInherited
Phenotypic Abnormality (PA)Abnormal glucose homeostasis0.2102InformativeInherited
Phenotypic Abnormality (PA)Hyperammonemia0.00000004298Highly InformativeDirect
Phenotypic Abnormality (PA)Coma0.00006225Highly InformativeDirect
Phenotypic Abnormality (PA)Psychomotor retardation0.0001791Highly InformativeDirect
Phenotypic Abnormality (PA)Vomiting0.0008592Highly InformativeDirect

Document: HP annotation of SCOP domains

Worm Phenotype (WP)

(show details)
WP termFDR (all)SDWP levelAnnotation (direct or inherited)
Worm Phenotype (WP)slow growth0Least InformativeDirect

Document: WP annotation of SCOP domains

Yeast Phenotype (YP)

(show details)
YP termFDR (all)SDYP levelAnnotation (direct or inherited)
Yeast Phenotype (YP)metabolism and growth0.2501Least InformativeInherited
Yeast Phenotype (YP)nutrient utilization0.1135Moderately InformativeInherited
Yeast Phenotype (YP)utilization of nitrogen source0.000636InformativeDirect

Document: YP annotation of SCOP domains

Fly Phenotype (FP)

(show details) Document: FP annotation of SCOP domains

Fly Anatomy (FA)

(show details)
FA termFDR (all)SDFA levelAnnotation (direct or inherited)
Fly Anatomy (FA)tagma0Least InformativeDirect
Fly Anatomy (FA)segment0Least InformativeDirect
Fly Anatomy (FA)multi-tissue structure0Least InformativeDirect
Fly Anatomy (FA)organ system subdivision0Least InformativeDirect

Document: FA annotation of SCOP domains

Xenopus Anatomy (XA)

(show details) Document: XA annotation of SCOP domains

Arabidopsis Plant Ontology (AP)

(show details)
AP termFDR (all)SDAP levelAnnotation (direct or inherited)
Plant structure DEvelopment stage (PDE)E expanded cotyledon stage0Least InformativeDirect
Plant structure DEvelopment stage (PDE)F mature embryo stage0Least InformativeDirect
Plant structure DEvelopment stage (PDE)C globular stage0Least InformativeDirect
Plant structure DEvelopment stage (PDE)D bilateral stage0Least InformativeDirect
Plant structure DEvelopment stage (PDE)LP.04 four leaves visible stage0Least InformativeDirect

Document: AP annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEC levelAnnotation (direct or inherited)
Enzyme Commission (EC)Transferases1Least InformativeInherited
Enzyme Commission (EC)Hydrolases1Least InformativeInherited
Enzyme Commission (EC)Ligases0Moderately InformativeDirect
Enzyme Commission (EC)Transferring one-carbon groups1Moderately InformativeInherited
Enzyme Commission (EC)Acting on carbon-nitrogen bonds, other than peptide bonds1Moderately InformativeInherited
Enzyme Commission (EC)Lyases1Moderately InformativeInherited
Enzyme Commission (EC)Forming carbon-nitrogen bonds0InformativeDirect
Enzyme Commission (EC)Carboxy-lyases0.5153InformativeInherited
Enzyme Commission (EC)Carbon--nitrogen ligases with glutamine as amido-N-donor0Highly InformativeDirect
Enzyme Commission (EC)In cyclic amides0.004386Highly InformativeInherited
Enzyme Commission (EC)Hydroxymethyl-, formyl- and related transferases0.3844Highly InformativeInherited
Enzyme Commission (EC)Cyclo-ligases1Highly InformativeInherited

Document: EC annotation of SCOP domains

Jump to [ Top of page · SCOP classification · Enzyme Commission (EC) · Disease Ontology (DO) · Human Phenotype (HP) · Worm Phenotype (WP) · Yeast Phenotype (YP) · Fly Phenotype (FP) · Fly Anatomy (FA) · Xenopus Anatomy (XA) · Arabidopsis Plant Ontology (AP) · Enzyme Commission (EC) ]

Internal database links

   
Superfamily level     Family level

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


   
Superfamily level     Family level

Alignments of sequences to 51 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Superfamily level

Browse and view proteins in genomes which have different domain combinations including a PreATP-grasp domain domain.


   
Superfamily level     Family level

Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Jump to [ Top of page · SCOP classification · Enzyme Commission (EC) · Disease Ontology (DO) · Human Phenotype (HP) · Worm Phenotype (WP) · Yeast Phenotype (YP) · Fly Phenotype (FP) · Fly Anatomy (FA) · Xenopus Anatomy (XA) · Arabidopsis Plant Ontology (AP) · Enzyme Commission (EC) · Internal database links ]