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RecA protein-like (ATPase-domain) family

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   Alpha and beta proteins (a/b) [ 51349] (147)
Fold:   P-loop containing nucleoside triphosphate hydrolases [ 52539]
Superfamily:   P-loop containing nucleoside triphosphate hydrolases [ 52540] (24)
Family:   RecA protein-like (ATPase-domain) [ 52670] (17)


Family statistics
Genomes (3,253) Uniprot 2018_03 genome PDB chains (SCOP 1.75)
Domains 22,810 220,760 43
Proteins 22,637 219,710 41


Enzyme Commission (EC)

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show details)
EC termFDR (all)SDEO levelAnnotation (direct or inherited)
Enzyme Commission (EC)Acting on acid anhydrides0Least InformativeDirect
Enzyme Commission (EC)In phosphorous-containing anhydrides1Moderately InformativeInherited
Enzyme Commission (EC)Nucleoside-triphosphatase0InformativeDirect
Enzyme Commission (EC)Acting on acid anhydrides; catalyzing transmembran0InformativeDirect

Document: EC annotation of SCOP domains

Disease Ontology (DO)

(show details)
DO termFDR (all)SDDO levelAnnotation (direct or inherited)
Disease Ontology (DO)genetic disease0.005723Moderately InformativeInherited
Disease Ontology (DO)hereditary breast ovarian cancer syndrome0.00002391InformativeDirect

Document: DO annotation of SCOP domains

Human Phenotype (HP)

(show details)
HP termFDR (all)SDHP levelAnnotation (direct or inherited)
Phenotypic Abnormality (PA)Abnormality of the genitourinary system0.03657Least InformativeInherited
Phenotypic Abnormality (PA)Abnormality of metabolism/homeostasis0.1153Least InformativeInherited
Phenotypic Abnormality (PA)Abnormality of limbs0.1333Least InformativeInherited
Phenotypic Abnormality (PA)Abnormality of the cardiovascular system0.1384Least InformativeInherited
Phenotypic Abnormality (PA)Abnormality of the digestive system0.1881Least InformativeInherited
Phenotypic Abnormality (PA)Abnormality of skeletal morphology0.2357Least InformativeInherited
Phenotypic Abnormality (PA)Abnormality of the eye0.2396Least InformativeInherited
Phenotypic Abnormality (PA)Abnormality of the immune system0.4308Least InformativeInherited
Phenotypic Abnormality (PA)Abnormality of the integument0.4997Least InformativeInherited
Phenotypic Abnormality (PA)Abnormality of the face0.6523Least InformativeInherited
Phenotypic Abnormality (PA)Abnormal reproductive system morphology0.005431Moderately InformativeInherited
Phenotypic Abnormality (PA)Neoplasm0.006312Moderately InformativeInherited
Phenotypic Abnormality (PA)Abnormal anterior eye segment morphology0.01453Moderately InformativeInherited
Phenotypic Abnormality (PA)Abnormality of the lower limb0.04077Moderately InformativeInherited
Phenotypic Abnormality (PA)Abnormality of the gastrointestinal tract0.0652Moderately InformativeInherited
Phenotypic Abnormality (PA)Localized skin lesion0.07405Moderately InformativeInherited
Phenotypic Abnormality (PA)Abnormal ocular adnexa morphology0.0752Moderately InformativeInherited
Phenotypic Abnormality (PA)Abnormality of digestive system morphology0.07955Moderately InformativeInherited
Phenotypic Abnormality (PA)Abnormality of the nose0.1362Moderately InformativeInherited
Phenotypic Abnormality (PA)Abnormality of the urinary system physiology0.1384Moderately InformativeInherited
Phenotypic Abnormality (PA)Abnormal vascular morphology0.1432Moderately InformativeInherited
Phenotypic Abnormality (PA)Unusual infection0.147Moderately InformativeInherited
Phenotypic Abnormality (PA)Abnormal joint morphology0.1712Moderately InformativeInherited
Phenotypic Abnormality (PA)Abnormality of the respiratory system0.1942Moderately InformativeInherited
Phenotypic Abnormality (PA)Abnormality of blood and blood-forming tissues0.227Moderately InformativeInherited
Phenotypic Abnormality (PA)Abnormality of the upper limb0.2289Moderately InformativeInherited
Phenotypic Abnormality (PA)Abnormality of the upper urinary tract0.2624Moderately InformativeInherited
Phenotypic Abnormality (PA)Abnormal heart morphology0.363Moderately InformativeInherited
Phenotypic Abnormality (PA)Abnormality of limb bone morphology0.7465Moderately InformativeInherited
Phenotypic Abnormality (PA)Abnormal oral cavity morphology1Moderately InformativeInherited
Phenotypic Abnormality (PA)Abnormal myocardium morphology0.001373InformativeInherited
Phenotypic Abnormality (PA)Abnormality of the synovia0.001722InformativeInherited
Phenotypic Abnormality (PA)Joint dislocation0.004112InformativeInherited
Phenotypic Abnormality (PA)Abnormal palate morphology0.006207InformativeInherited
Phenotypic Abnormality (PA)Abnormality of the palpebral fissures0.006212InformativeInherited
Phenotypic Abnormality (PA)Abnormality of skin pigmentation0.007417InformativeInherited
Phenotypic Abnormality (PA)Abnormal finger phalanx morphology0.02023InformativeInherited
Phenotypic Abnormality (PA)Abnormal cellular physiology0.02282InformativeInherited
Phenotypic Abnormality (PA)Abnormality of pelvic girdle bone morphology0.02324InformativeInherited
Phenotypic Abnormality (PA)Abnormality of long bone morphology0.03798InformativeInherited
Phenotypic Abnormality (PA)Aplasia/hypoplasia of the extremities0.04294InformativeInherited
Phenotypic Abnormality (PA)Abnormality of prenatal development or birth0.04908InformativeInherited
Phenotypic Abnormality (PA)Abnormality of lower limb joint0.05591InformativeInherited
Phenotypic Abnormality (PA)Abnormality of the upper respiratory tract0.05916InformativeInherited
Phenotypic Abnormality (PA)Abnormality of toe0.07986InformativeInherited
Phenotypic Abnormality (PA)Anemia0.08101InformativeInherited
Phenotypic Abnormality (PA)Recurrent infections0.1229InformativeInherited
Phenotypic Abnormality (PA)Abnormality of the uterus0.1494InformativeInherited
Phenotypic Abnormality (PA)Abnormality of reproductive system physiology0.1918InformativeInherited
Phenotypic Abnormality (PA)Abnormal intestine morphology0.2078InformativeInherited
Phenotypic Abnormality (PA)Abnormal systemic arterial morphology0.2162InformativeInherited
Phenotypic Abnormality (PA)Abnormality of calvarial morphology0.548InformativeInherited
Phenotypic Abnormality (PA)Abnormality of male external genitalia0.9669InformativeInherited
Phenotypic Abnormality (PA)Breast carcinoma0.0000048Highly InformativeDirect
Phenotypic Abnormality (PA)Prostate neoplasm0.00001488Highly InformativeDirect
Phenotypic Abnormality (PA)Abnormality of the uvula0.00004084Highly InformativeDirect
Phenotypic Abnormality (PA)Hydroureter0.00005404Highly InformativeDirect
Phenotypic Abnormality (PA)Triangular shaped phalanges of the hand0.0001278Highly InformativeDirect
Phenotypic Abnormality (PA)Decreased fertility in males0.0001597Highly InformativeDirect
Phenotypic Abnormality (PA)High palate0.0003701Highly InformativeDirect
Phenotypic Abnormality (PA)Choanal atresia0.0006151Highly InformativeDirect
Phenotypic Abnormality (PA)Azoospermia0.0006455Highly InformativeDirect
Phenotypic Abnormality (PA)Hyperpigmentation of the skin0.0007784Highly InformativeDirect
Phenotypic Abnormality (PA)Abnormal trachea morphology0.001378Highly InformativeInherited
Phenotypic Abnormality (PA)Anemia of inadequate production0.001534Highly InformativeInherited
Phenotypic Abnormality (PA)Abnormality of the ulna0.001829Highly InformativeInherited
Phenotypic Abnormality (PA)Abnormal thumb morphology0.001877Highly InformativeInherited
Phenotypic Abnormality (PA)Cafe-au-lait spot0.002352Highly InformativeInherited
Phenotypic Abnormality (PA)Abnormality of the anus0.002356Highly InformativeInherited
Phenotypic Abnormality (PA)Syndactyly0.002436Highly InformativeInherited
Phenotypic Abnormality (PA)Abnormality of the radius0.004551Highly InformativeInherited
Phenotypic Abnormality (PA)Abnormality of the phalanges of the toes0.01459Highly InformativeInherited
Phenotypic Abnormality (PA)Abnormal esophagus morphology0.01961Highly InformativeInherited
Phenotypic Abnormality (PA)Abnormality of the penis0.02663Highly InformativeInherited
Phenotypic Abnormality (PA)Hematological neoplasm0.03481Highly InformativeInherited
Phenotypic Abnormality (PA)Aplasia/Hypoplasia affecting the eye0.04579Highly InformativeInherited
Phenotypic Abnormality (PA)Abnormality of the small intestine0.04663Highly InformativeInherited
Phenotypic Abnormality (PA)Abnormality of the amniotic fluid0.07614Highly InformativeInherited
Phenotypic Abnormality (PA)Ocular anterior segment dysgenesis0.07617Highly InformativeInherited

Document: HP annotation of SCOP domains

Mouse Phenotype (MP)

(show details)
MP termFDR (all)SDMP levelAnnotation (direct or inherited)
Mammalian Phenotype (MP)mortality/aging0.09022Least InformativeInherited
Mammalian Phenotype (MP)prenatal lethality0.0005909Moderately InformativeDirect

Document: MP annotation of SCOP domains

Worm Phenotype (WP)

(show details)
WP termFDR (all)SDWP levelAnnotation (direct or inherited)
Worm Phenotype (WP)organism metabolism processing variant0Least InformativeDirect
Worm Phenotype (WP)cell morphology variant0.0003615Least InformativeDirect
Worm Phenotype (WP)cell development variant0.0005114Least InformativeDirect
Worm Phenotype (WP)cell physiology variant0.001666Least InformativeInherited
Worm Phenotype (WP)blast cell physiology variant0.001666Least InformativeInherited
Worm Phenotype (WP)organism behavior variant0.03209Least InformativeInherited
Worm Phenotype (WP)cell organization biogenesis variant0.000001303Moderately InformativeDirect
Worm Phenotype (WP)cell death variant0.000001911Moderately InformativeDirect
Worm Phenotype (WP)cell division variant0.000009008Moderately InformativeDirect
Worm Phenotype (WP)early embryonic lethal0.00001002Moderately InformativeDirect
Worm Phenotype (WP)germ cell development variant0.00001228Moderately InformativeDirect
Worm Phenotype (WP)protein protein interaction variant0.000217Moderately InformativeDirect
Worm Phenotype (WP)reproductive system morphology variant0.000581Moderately InformativeDirect
Worm Phenotype (WP)organ system development variant0.01278Moderately InformativeInherited
Worm Phenotype (WP)germ cell differentiation variant0.1196Moderately InformativeInherited
Worm Phenotype (WP)pattern of transgene expression variant0.187Moderately InformativeInherited
Worm Phenotype (WP)level of transgene expression variant0.2643Moderately InformativeInherited
Worm Phenotype (WP)cell type morphology variant0.4009Moderately InformativeInherited
Worm Phenotype (WP)diplotene progression during oogenesis variant0.0000002778InformativeDirect
Worm Phenotype (WP)vesicle morphology variant0.0000005876InformativeDirect
Worm Phenotype (WP)accumulated germline cell corpses0.0000006267InformativeDirect
Worm Phenotype (WP)oocyte morphology variant0.000009863InformativeDirect
Worm Phenotype (WP)avoids bacterial lawn0.00009915InformativeDirect
Worm Phenotype (WP)transgene expression increased0.0001388InformativeDirect
Worm Phenotype (WP)gonad development variant0.0001614InformativeDirect
Worm Phenotype (WP)cell component localization variant0.008332InformativeInherited
Worm Phenotype (WP)mitosis variant0.02113InformativeInherited
Worm Phenotype (WP)meiotic chromosome organization variant0.2149InformativeInherited
Worm Phenotype (WP)diplotene region organization variant0.00000003168Highly InformativeDirect
Worm Phenotype (WP)germ cell compartment anucleate0.0000008145Highly InformativeDirect
Worm Phenotype (WP)oocyte septum formation variant0.000002284Highly InformativeDirect
Worm Phenotype (WP)RAB-11 recycling endosome localization variant0.000007015Highly InformativeDirect
Worm Phenotype (WP)chromosome condensation variant0.00000801Highly InformativeDirect
Worm Phenotype (WP)lysosome-related organelle morphology variant0.0001396Highly InformativeDirect

Document: WP annotation of SCOP domains

Yeast Phenotype (YP)

(show details)
YP termFDR (all)SDYP levelAnnotation (direct or inherited)
Yeast Phenotype (YP)metabolism and growth0Least InformativeDirect
Yeast Phenotype (YP)resistance to chemicals0.6505Least InformativeInherited
Yeast Phenotype (YP)development0Moderately InformativeDirect
Yeast Phenotype (YP)oxidative stress resistance0.000196InformativeDirect
Yeast Phenotype (YP)desiccation resistance0.0004088InformativeDirect
Yeast Phenotype (YP)sexual cycle0.01197InformativeInherited
Yeast Phenotype (YP)sporulation0.00001857Highly InformativeDirect
Yeast Phenotype (YP)alkaline pH resistance0.00007058Highly InformativeDirect
Yeast Phenotype (YP)starvation resistance0.0003333Highly InformativeDirect
Yeast Phenotype (YP)resistance to enzymatic treatment0.0003885Highly InformativeDirect

Document: YP annotation of SCOP domains

Fly Phenotype (FP)

(show details)
FP termFDR (all)SDFP levelAnnotation (direct or inherited)
Fly Phenotype (FP)cell cycle defective0.0008381InformativeDirect

Document: FP annotation of SCOP domains

Fly Anatomy (FA)

(show details)
FA termFDR (all)SDFA levelAnnotation (direct or inherited)
Fly Anatomy (FA)multi-tissue structure0Least InformativeDirect
Fly Anatomy (FA)female organism0.0342Moderately InformativeInherited
Fly Anatomy (FA)gonad0.05479Moderately InformativeInherited
Fly Anatomy (FA)acellular anatomical structure0.06689Moderately InformativeInherited
Fly Anatomy (FA)egg0.003075InformativeInherited
Fly Anatomy (FA)female germline cyst0.01448InformativeInherited
Fly Anatomy (FA)germline cell0.01863InformativeInherited
Fly Anatomy (FA)cell component0.02467InformativeInherited
Fly Anatomy (FA)dorsal appendage0.0002044Highly InformativeDirect
Fly Anatomy (FA)female germline cell0.0002754Highly InformativeDirect
Fly Anatomy (FA)oocyte0.0005553Highly InformativeDirect

Document: FA annotation of SCOP domains

Zebrafish Anatomy (ZA)

(show details) Document: ZA annotation of SCOP domains

Xenopus Anatomy (XA)

(show details) Document: XA annotation of SCOP domains

Arabidopsis Plant Ontology (AP)

(show details)
AP termFDR (all)SDAP levelAnnotation (direct or inherited)
Plant structure DEvelopment stage (PDE)seed development stage0.00024InformativeDirect

Document: AP annotation of SCOP domains

Enzyme Commission (EC)

(show details)
EC termFDR (all)SDEC levelAnnotation (direct or inherited)
Enzyme Commission (EC)Transferases1Least InformativeInherited
Enzyme Commission (EC)Hydrolases1Least InformativeInherited
Enzyme Commission (EC)Acting on acid anhydrides0.6624Moderately InformativeInherited
Enzyme Commission (EC)Phosphotransferases with an alcohol group as acceptor1Moderately InformativeInherited
Enzyme Commission (EC)Nucleotidyltransferases1Moderately InformativeInherited
Enzyme Commission (EC)Translocases0InformativeDirect
Enzyme Commission (EC)In phosphorus-containing anhydrides0.05219InformativeInherited
Enzyme Commission (EC)Transferring alkyl or aryl groups, other than methyl groups1InformativeInherited
Enzyme Commission (EC)Nucleoside-triphosphate phosphatase0Highly InformativeDirect
Enzyme Commission (EC)Catalysing the translocation of inorganic cations1Highly InformativeInherited

Document: EC annotation of SCOP domains

Jump to [ Top of page · SCOP classification · Enzyme Commission (EC) · Disease Ontology (DO) · Human Phenotype (HP) · Mouse Phenotype (MP) · Worm Phenotype (WP) · Yeast Phenotype (YP) · Fly Phenotype (FP) · Fly Anatomy (FA) · Zebrafish Anatomy (ZA) · Xenopus Anatomy (XA) · Arabidopsis Plant Ontology (AP) · Enzyme Commission (EC) ]

Internal database links

   
Superfamily level     Family level

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


   
Superfamily level     Family level

Alignments of sequences to 512 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Superfamily level

Browse and view proteins in genomes which have different domain combinations including a P-loop containing nucleoside triphosphate hydrolases domain.


   
Superfamily level     Family level

Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Jump to [ Top of page · SCOP classification · Enzyme Commission (EC) · Disease Ontology (DO) · Human Phenotype (HP) · Mouse Phenotype (MP) · Worm Phenotype (WP) · Yeast Phenotype (YP) · Fly Phenotype (FP) · Fly Anatomy (FA) · Zebrafish Anatomy (ZA) · Xenopus Anatomy (XA) · Arabidopsis Plant Ontology (AP) · Enzyme Commission (EC) · Internal database links ]