SUPERFAMILY 1.73 HMM library and genome assignments server


Aminoacid dehydrogenase-like, N-terminal domain superfamily

SCOP classification
Root:   SCOP hierarchy in SUPERFAMILY [ 0] (11)
Class:   Alpha and beta proteins (a/b) [ 51349] (141)
  Mainly parallel beta sheets (beta-alpha-beta units)
Fold:   Aminoacid dehydrogenase-like, N-terminal domain [ 53222]
  core: 3 layers: a/b/a; parallel beta-sheet of 4 strands; 2134
Superfamily:   Aminoacid dehydrogenase-like, N-terminal domain [ 53223] (5)
Families:   Aminoacid dehydrogenases [ 53224] (3)
  dimerisation domain; contains additional structures including two extra N-terminal strands in the beta-sheet
  Tetrahydrofolate dehydrogenase/cyclohydrolase [ 53235]
  Methylene-tetrahydromethanopterin dehydrogenase [ 82333]
  Shikimate dehydrogenase-like [ 82336] (3)
  Malic enzyme N-domain [ 53240] (2)
  Pfam 00390; decorated with additional structures; includes N-terminal additional subdomains and extra N-terminal strand


Superfamily statistics
Genomes (1,224) UniProt 15.0 PDB chains (SCOP 1.73)
Domains 7,060 8,185 42
Proteins 7,053 8,177 42


Functional annotation
General category Metabolism
Detailed category Redox

Function annotation of SCOP domain superfamilies

Jump to [ Top of page · SCOP classification · Functional annotation ]

Internal database links

Browse genome assignments for this superfamily. The SUPERFAMILY hidden Markov model library has been used to carry out SCOP domain assignments to all genomes at the superfamily level.


Alignments of sequences to 22 models in this superfamily are available by clicking on the 'Alignments' icon above. PDB sequences less than 40% identical are shown by default, but any other sequence(s) may be aligned. Select PDB sequences, genome sequences, or paste in or upload your own sequences.


Browse and view proteins in genomes which have different domain combinations including a Aminoacid dehydrogenase-like, N-terminal domain domain.


Examine the distribution of domain superfamilies, or families, across the major taxonomic kingdoms or genomes within a kingdom. This gives an immediate impression of how superfamilies, or families, are restricted to certain kingdoms of life.


Explore domain occurrence network where nodes represent genomes and edges are domain architectures (shared between genomes) containing the superfamily of interest.

There are 22 hidden Markov models representing the Aminoacid dehydrogenase-like, N-terminal domain superfamily. Information on how the models are built, and plots showing hydrophobicity, match emmission probabilities and insertion/deletion probabilities can be inspected.


Jump to [ Top of page · SCOP classification · Functional annotation · Internal database links ]